Interference with the contractile machinery of the fibroblastic chondrocyte cytoskeleton induces re-expression of the cartilage phenotype through involvement of PI3K, PKC and MAPKs

Experimental Cell Research

Volumn 320, Issue 2, 2014, Pages 175-187

  Rottmar, Markus ^a   Mhanna, Rami ^b   Guimond Lischer, Stefanie ^a   Vogel, Viola ^b   Zenobi Wong, Marcy ^b   Maniura Weber, Katharina ^a  

^a Laboratory for Materials Biology Interactions   (Switzerland)

^b ETH ZURICH   (Switzerland)

Author keywords

Actin cytoskeleton; Cell contractility; Chondrocyte; PI3K, PKC, MAPK, ILK; Re differentiation; Staurosporine

Indexed keywords

ACTIN; BLEBBISTATIN; CELL MARKER; COLLAGEN TYPE 2; CYTOCHALASIN D; GLYCOSAMINOGLYCAN; INTEGRIN LINKED KINASE; MIDOSTAURIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; MYOSIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE C; SMALL INTERFERING RNA; STAUROSPORINE;

ACTIN FILAMENT; ANIMAL CELL; ARTICLE; CARTILAGE; CARTILAGE CELL; CELL ACTIVITY; CELL CULTURE; CELL DIFFERENTIATION; CHONDROGENESIS; CONTROLLED STUDY; CYTOARCHITECTURE; CYTOSKELETON; DOWN REGULATION; FIBROBLAST; GLYCOSAMINOGLYCAN METABOLISM; INTRACELLULAR SIGNALING; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION;

ACTIN CYTOSKELETON; CELL CONTRACTILITY; CHONDROCYTE; ERK; EXTRACELLULAR SIGNALING REGULATED KINASE; GAG; GLYCOSAMINOGLYCAN; ILK; INTEGRIN-LINKED KINASE; MAPK; MEK; MITOGEN-ACTIVATED PROTEIN KINASE; MITOGEN-ACTIVATED PROTEIN KINASE KINASE; PHOSPHOINOSITIDE-3-KINASE; PI3K; PI3K, PKC, MAPK, ILK; PKC; PROTEIN KINASE C; RE-DIFFERENTIATION; STAUROSPORINE;

ACTININ; ANIMALS; CARTILAGE; CATTLE; CELL DIFFERENTIATION; CELLS, CULTURED; CHONDROCYTES; CYTOCHALASIN D; CYTOSKELETON; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FIBROBLASTS; GENE EXPRESSION REGULATION; MYOSINS; PHENOTYPE; PHOSPHATIDYLINOSITOL 3-KINASES; PROTEIN KINASE C; STAUROSPORINE;

EID: 84890858742     PISSN: 00144827     EISSN: 10902422     Source Type: Journal    
DOI: 10.1016/j.yexcr.2013.11.004     Document Type: Article

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