Disruption of actin cytoskeleton induces chondrogenesis of mesenchymal cells by activating protein kinase C-α signaling

Biochemical and Biophysical Research Communications

Volumn 273, Issue 2, 2000, Pages 609-613

  Lim, Young Bin ^a   Kang, Shin Sung ^a   Park, Tae Kyu ^a   Lee, Young Sup ^a   Chun, Jang Soo ^b   Sonn, Jong Kyung ^a  

^a Kyungpook National University   (South Korea)

^b Gwangju Institute of Science and Technology (GIST)   (South Korea)

Author keywords

Chondrogenesis; Cytoskeleton; MAP kinase; PKC

Indexed keywords

ACTIN; COLLAGEN TYPE 2; CYTOCHALASIN D; ISOPROTEIN; LATRUNCULIN B; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE C;

ANIMAL CELL; ARTICLE; CELL DENSITY; CHICK EMBRYO; CHONDROGENESIS; CONTROLLED STUDY; CYTOSKELETON; DOSE RESPONSE; GENE EXPRESSION REGULATION; MESENCHYME; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

ANIMALIA;

EID: 0033871679     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.2000.2987     Document Type: Article

References (19)

1. Marchesi V. T. Stabilizing infrastructure of cell membranes. Annu. Rev. Cell Biol. 1:1985;531-561.
2. Wezeman F. H. Morphological foundations of precartilage development in mesenchyme. Microsc. Res. Tech. 43:1998;91-101.
3. Gould R. P., Day A., Wolpert L. Mesenchymal condensation and cell contact in early morphogenesis of the chick limb. Exp. Cell Res. 72:1972;325-336.
4. Thorogood P. V., Hinchliffe J. R. An analysis of the condensation process during chondrogenesis in the embryonic chick hind limb. J. Embryol. Exp. Morphol. 33:1975;581-606.
5. Solursh M., Ahrens P. B., Reiter R. S. A tissue culture analysis of the steps in limb chondrogenesis. In Vitro. 14:1978;51-61.
6. Archer C. W., Rooney P., Wolpert L. Cell shape and cartilage differentiation of early chick limb bud cells in culture. Cell Differ. 11:1982;245-251.
7. Solursh M., Linsenmayer T. F., Jensen K. L. Chondrogenesis from single limb mesenchyme cells. Dev. Biol. 94:1982;259-264.
8. Zanetti N. C., Solursh M. Induction of chondrogenesis in limb mesenchymal cultures by disruption of the actin cytoskeleton. J. Cell Biol. 99:1984;115-123.
9. Loty S., Forest N., Boulekbache H., Sautier J. M. Cytochalasin D induces changes in cell shape and promotes in vitro chondrogenesis: A morphological study. Biol. Cell. 83:1995;149-161.
10. Sonn J. K., Solursh M. Activity of protein kinase C during the differentiation of chick limb bud mesenchymal cells. Differentiation. 53:1993;155-162.
11. Choi B., Chun J.-S., Lee Y.-S., Sonn J. K., Kang S.-S. Expression of protein kinase C isozymes that are required for chondrogenesis of chick limb bud mesenchymal cells. Biochem. Biophys. Res. Commun. 216:1995;1034-1040.
12. Yang M.-S., Chang S.-H., Sonn J. K., Lee Y.-S., Kang S.-S., Park T.-K., Chun J.-S. Regulation of chondrogenic differentiation of mesenchymes by protein kinase Cα Mol. Cells. 8:1998;266-271.
13. Chang S.-H., Oh C.-D., Yang M.-S., Kang S.-S., Lee Y.-S., Sonn J.-K., Chun J.-S. Protein kinase C regulates chondrogenesis of mesenchymes via mitogen-activated protein kinase signaling. J. Biol. Chem. 273:1998;19213-19219.
14. Hamburger V., Hamilton H. W. A series of normal stages in the development of the chick embryo. J. Morphol. 88:1951;49-92.
15. Ahrens P.-B., Solursh M., Reiter R.-S. Stage-related capacity for limb chondrogenesis in cell culture. Dev. Biol. 60:1977;69-82.
16. Lev R., Spicer S. S. Specific staining of sulfate groups with Alcian blue at low pH. J. Histochem. Cytochem. 12:1964;309.
17. Spector I., Shochet N. R., Kashman Y., Groweiss A. Latrunculins: Novel marine toxins that disrupt microfilament organization in cultured cells. Science. 219:1983;493-495.
18. Martiny-Baron G., Kazanietz M. G., Mischak H., Blumberg P. M., Kochs G., Hug H., Marme D., Schachtele C. Selective inhibition of protein kinase C isozymes by the indolocarbazole Go 6976. J. Biol. Chem. 268:1993;9194-9197.
19. Irigoyen J. P., Besser D., Nagamine Y. Cytoskeleton reorganization induces the urokinase-type plasminogen activator gene via the Ras/extracellular signal-regulated kinase (ERK) signaling pathway. J. Biol. Chem. 272:1997;1904-1909.