High-throughput screening normalized to biological response: Application to antiviral drug discovery

Journal of Biomolecular Screening

Volumn 19, Issue 1, 2014, Pages 119-130

  Patel, Dhara A ^a   Patel, Anand C ^a   Nolan, William C ^a   Huang, Guangming ^a   Romero, Arthur G ^a   Charlton, Nichole ^a   Agapov, Eugene ^a   Zhang, Yong ^a   Holtzman, Michael J ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

cell based assay; interferon signal enhancer; phenotypic drug discovery; quantitative HTS; statin

Indexed keywords

ANTIVIRUS AGENT; INTERFERON; STAT1 PROTEIN; STAT2 PROTEIN;

ARTICLE; AUTOMATION; CHEMICAL STRUCTURE; GENE EXPRESSION; HIGH THROUGHPUT SCREENING; PRIORITY JOURNAL; TREATMENT RESPONSE;

CELL-BASED ASSAY; INTERFERON SIGNAL ENHANCER; PHENOTYPIC DRUG DISCOVERY; QUANTITATIVE HTS; STATIN;

ANTIVIRAL AGENTS; DRUG DISCOVERY; DRUG EVALUATION, PRECLINICAL; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENES, REPORTER; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; INTERFERON REGULATORY FACTORS; REPRODUCIBILITY OF RESULTS; RESPONSE ELEMENTS; SMALL MOLECULE LIBRARIES;

EID: 84890834997     PISSN: 10870571     EISSN: 1552454X     Source Type: Journal    
DOI: 10.1177/1087057113496848     Document Type: Article

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