High-dose atorvastatin reduces periodontal inflammation: A novel pleiotropic effect of statins

Journal of the American College of Cardiology

Volumn 62, Issue 25, 2013, Pages 2382-2391

  Subramanian, Sharath ^a   Emami, Hamed ^a   Vucic, Esad ^a   Singh, Parmanand ^a   Vijayakumar, Jayanthi ^a   Fifer, Kenneth M ^a   Alon, Achilles ^b   Shankar, Sudha S ^b   Farkouh, Michael ^c   Rudd, James H F ^d   Fayad, Zahi A ^e   Van Dyke, Thomas E ^f   Tawakol, Ahmed ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b MERCK RESEARCH LABORATORIES   (United States)

^c UNIVERSITY OF TORONTO   (Canada)

^d UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^e MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^f FORSYTH INSTITUTE   (United States)

Author keywords

atherosclerosis; imaging; inflammation; nuclear medicine; statins

Indexed keywords

ATORVASTATIN; FLUORODEOXYGLUCOSE F 18; PLACEBO;

ADULT; AGED; ARTICLE; ATHEROSCLEROSIS; CLINICAL EVALUATION; COMPUTER ASSISTED EMISSION TOMOGRAPHY; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE ASSOCIATION; DISEASE SEVERITY; DOSE RESPONSE; DOUBLE BLIND PROCEDURE; DRUG ACTIVITY; DRUG EFFECT; DRUG MEGADOSE; DRUG WITHDRAWAL; FEMALE; HUMAN; IMAGE ANALYSIS; LOW DRUG DOSE; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; MULTICENTER STUDY; OSTEOLYSIS; PERIODONTITIS; PLEIOTROPY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RISK ASSESSMENT; RISK FACTOR; RISK REDUCTION; TREATMENT DURATION; UNSPECIFIED SIDE EFFECT; VERY ELDERLY;

EID: 84890627997     PISSN: 07351097     EISSN: 15583597     Source Type: Journal    
DOI: 10.1016/j.jacc.2013.08.1627     Document Type: Article

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