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Volumn 8, Issue 4, 2013, Pages 271-280

Gastric cancer (GC) patients with hedgehog pathway activation: PTCH1 and GLI2 as independent prognostic factors

Author keywords

Gastric cancer; Hedgehog pathway; Prognosis; PTCH1; SMO

Indexed keywords

HEPATOCYTE NUCLEAR FACTOR 3BETA; MESSENGER RNA; PROTEIN PATCHED 1; SMOOTHENED PROTEIN; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR GLI2; TUMOR MARKER; VISMODEGIB;

EID: 84890572199     PISSN: 17762596     EISSN: 1776260X     Source Type: Journal    
DOI: 10.1007/s11523-013-0253-1     Document Type: Article
Times cited : (28)

References (33)
  • 1
    • 0345059765 scopus 로고    scopus 로고
    • Hedgehog signalling in cancer formation and maintenance
    • 14737121 10.1038/nrc1229
    • Pasca Di Magliano M, Hebrok M (2003) Hedgehog signalling in cancer formation and maintenance. Nat Rev Cancer 3:903-911
    • (2003) Nat Rev Cancer , vol.3 , pp. 903-911
    • Pasca Di Magliano, M.1    Hebrok, M.2
  • 2
    • 0035902140 scopus 로고    scopus 로고
    • The Hedgehog and Wnt signalling pathways in cancer
    • 11357142 10.1038/35077219 1:CAS:528:DC%2BD3MXktVSjsrw%3D
    • Taipale J, Beachy PA (2001) The Hedgehog and Wnt signalling pathways in cancer. Nature 411:349-354
    • (2001) Nature , vol.411 , pp. 349-354
    • Taipale, J.1    Beachy, P.A.2
  • 3
    • 50649088457 scopus 로고    scopus 로고
    • Pattern formation in the vertebrate neural tube: A sonic hedgehog morphogen-regulated transcriptional network
    • 18621990 10.1242/dev.009324 1:CAS:528:DC%2BD1cXhtVGqt73E
    • Dessaud E, McMahon AP, Briscoe J (2008) Pattern formation in the vertebrate neural tube: a sonic hedgehog morphogen-regulated transcriptional network. Development 135:2489-2503
    • (2008) Development , vol.135 , pp. 2489-2503
    • Dessaud, E.1    McMahon, A.P.2    Briscoe, J.3
  • 4
    • 0033916281 scopus 로고    scopus 로고
    • Hedgehog signals regulate multiple aspects of gastrointestinal development
    • 10821773 1:CAS:528:DC%2BD3cXkslOrs70%3D
    • Ramalho-Santos M, Melton DA, McMahon AP (2000) Hedgehog signals regulate multiple aspects of gastrointestinal development. Development 127:2763-2772
    • (2000) Development , vol.127 , pp. 2763-2772
    • Ramalho-Santos, M.1    Melton, D.A.2    McMahon, A.P.3
  • 5
    • 0029777408 scopus 로고    scopus 로고
    • Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function
    • 8837770 10.1038/383407a0 1:CAS:528:DyaK28Xmt1ykt7k%3D
    • Chiang C, Litingtung Y, Lee E, Young KE, Corden JL, Westphal H, Beachy PA (1996) Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function. Nature 383:407-413
    • (1996) Nature , vol.383 , pp. 407-413
    • Chiang, C.1    Litingtung, Y.2    Lee, E.3    Young, K.E.4    Corden, J.L.5    Westphal, H.6    Beachy, P.A.7
  • 6
    • 0029948270 scopus 로고    scopus 로고
    • Biochemical evidence that patched is the Hedgehog receptor
    • 8906794 10.1038/384176a0 1:CAS:528:DyaK28XmvFGgsrk%3D
    • Marigo V, Davey RA, Zuo Y, Cunningham JM, Tabin CJ (1996) Biochemical evidence that patched is the Hedgehog receptor. Nature 384:176-179
    • (1996) Nature , vol.384 , pp. 176-179
    • Marigo, V.1    Davey, R.A.2    Zuo, Y.3    Cunningham, J.M.4    Tabin, C.J.5
  • 8
    • 0034721665 scopus 로고    scopus 로고
    • Transducing the hedgehog signal
    • 11081624 10.1016/S0092-8674(00)00129-X 1:CAS:528:DC%2BD3cXnvF2ksrg%3D
    • Kalderon D (2000) Transducing the hedgehog signal. Cell 103:371-374
    • (2000) Cell , vol.103 , pp. 371-374
    • Kalderon, D.1
  • 9
    • 0031679850 scopus 로고    scopus 로고
    • Gli2 is required for induction of floor plate and adjacent cells, but not most ventral neurons in the mouse central nervous system
    • 9655799 1:CAS:528:DyaK1cXls1Sntbg%3D
    • Matise MP, Epstein DJ, Park HL, Platt KA, Joyner AL (1998) Gli2 is required for induction of floor plate and adjacent cells, but not most ventral neurons in the mouse central nervous system. Development 125:2759-2770
    • (1998) Development , vol.125 , pp. 2759-2770
    • Matise, M.P.1    Epstein, D.J.2    Park, H.L.3    Platt, K.A.4    Joyner, A.L.5
  • 11
    • 0037439152 scopus 로고    scopus 로고
    • Sonic hedgehog-dependent activation of Gli2 is essential for embryonic hair follicle development
    • 12533516 10.1101/gad.1038103 1:CAS:528:DC%2BD3sXmtFyhtg%3D%3D
    • Mill P, Mo R, Fu H, Grachtchouk M, Kim PC, Dlugosz AA, Hui CC (2003) Sonic hedgehog-dependent activation of Gli2 is essential for embryonic hair follicle development. Genes Dev 17:282-294
    • (2003) Genes Dev , vol.17 , pp. 282-294
    • Mill, P.1    Mo, R.2    Fu, H.3    Grachtchouk, M.4    Kim, P.C.5    Dlugosz, A.A.6    Hui, C.C.7
  • 12
    • 0031683165 scopus 로고    scopus 로고
    • Essential function of Gli2 and Gli3 in the formation of lung, trachea and oesophagus
    • 9731531 10.1038/1711 1:CAS:528:DyaK1cXmtVOmtLg%3D
    • Motoyama J, Liu J, Mo R, Ding Q, Post M, Hui CC (1998) Essential function of Gli2 and Gli3 in the formation of lung, trachea and oesophagus. Nat Genet 20:54-57
    • (1998) Nat Genet , vol.20 , pp. 54-57
    • Motoyama, J.1    Liu, J.2    Mo, R.3    Ding, Q.4    Post, M.5    Hui, C.C.6
  • 16
    • 0030802458 scopus 로고    scopus 로고
    • Induction of basal cell carcinoma features in transgenic human skin expressing Sonic Hedgehog
    • 9212109 10.1038/nm0797-788 1:CAS:528:DyaK2sXkt1Kqsbk%3D
    • Fan H, Oro AE, Scott MP, Khavari PA (1997) Induction of basal cell carcinoma features in transgenic human skin expressing Sonic Hedgehog. Nat Med 3:788-792
    • (1997) Nat Med , vol.3 , pp. 788-792
    • Fan, H.1    Oro, A.E.2    Scott, M.P.3    Khavari, P.A.4
  • 20
    • 0242669237 scopus 로고    scopus 로고
    • Hedgehog signalling within airway epithelial progenitors and in small-cell lung cancer
    • 12629553 10.1038/nature01493 1:CAS:528:DC%2BD3sXitFKmu7s%3D
    • Watkins DN, Berman DM, Burkholder SG, Wang B, Beachy PA, Baylin SB (2003) Hedgehog signalling within airway epithelial progenitors and in small-cell lung cancer. Nature 422:313-317
    • (2003) Nature , vol.422 , pp. 313-317
    • Watkins, D.N.1    Berman, D.M.2    Burkholder, S.G.3    Wang, B.4    Beachy, P.A.5    Baylin, S.B.6
  • 21
    • 27144541492 scopus 로고    scopus 로고
    • Frequent activation of the hedgehog pathway in advanced gastric adenocarcinomas
    • 15905200 10.1093/carcin/bgi130 1:CAS:528:DC%2BD2MXhtVWnt7bO
    • Ma X, Chen K, Huang S, Zhang X, Adegboyega PA, Evers BM, Zhang H, Xie J (2005) Frequent activation of the hedgehog pathway in advanced gastric adenocarcinomas. Carcinogenesis 26:1698-1705
    • (2005) Carcinogenesis , vol.26 , pp. 1698-1705
    • Ma, X.1    Chen, K.2    Huang, S.3    Zhang, X.4    Adegboyega, P.A.5    Evers, B.M.6    Zhang, H.7    Xie, J.8
  • 23
    • 33746266049 scopus 로고    scopus 로고
    • Study of Sonic hedgehog signaling pathway related molecules in gastric carcinoma
    • 16810741 1:CAS:528:DC%2BD28XotFaqsro%3D
    • Ma XL, Sun HJ, Wang YS, Huang SH, Xie JW, Zhang HW (2006) Study of Sonic hedgehog signaling pathway related molecules in gastric carcinoma. World J Gastroenterol 12:3965-3969
    • (2006) World J Gastroenterol , vol.12 , pp. 3965-3969
    • Ma, X.L.1    Sun, H.J.2    Wang, Y.S.3    Huang, S.H.4    Xie, J.W.5    Zhang, H.W.6
  • 27
    • 77956262693 scopus 로고    scopus 로고
    • Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): A phase 3, open-label, randomised controlled trial
    • 20728210 10.1016/S0140-6736(10)61121-X 1:CAS:528:DC%2BC3cXhtVymt7zO
    • Bang YJ, Van Cutsem E, Feyereislova A, Chung HC, Shen L, Sawaki A, Lordick F, Ohtsu A, Omuro Y, Satoh T, Aprile G, Kulikov E, Hill J, Lehle M, Ruschoff J, Kang YK (2010) Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): a phase 3, open-label, randomised controlled trial. Lancet 376:687-697
    • (2010) Lancet , vol.376 , pp. 687-697
    • Bang, Y.J.1    Van Cutsem, E.2    Feyereislova, A.3    Chung, H.C.4    Shen, L.5    Sawaki, A.6    Lordick, F.7    Ohtsu, A.8    Omuro, Y.9    Satoh, T.10    Aprile, G.11    Kulikov, E.12    Hill, J.13    Lehle, M.14    Ruschoff, J.15    Kang, Y.K.16
  • 30
    • 34249011892 scopus 로고    scopus 로고
    • Gas1 extends the range of Hedgehog action by facilitating its signaling
    • 17504940 10.1101/gad.1546307 1:CAS:528:DC%2BD2sXls1aqu7Y%3D
    • Martinelli DC, Fan CM (2007) Gas1 extends the range of Hedgehog action by facilitating its signaling. Genes Dev 21:1231-1243
    • (2007) Genes Dev , vol.21 , pp. 1231-1243
    • Martinelli, D.C.1    Fan, C.M.2
  • 31
    • 79958210024 scopus 로고    scopus 로고
    • Boc and Gas1 each form distinct Shh receptor complexes with Ptch1 and are required for Shh-mediated cell proliferation
    • 21664577 10.1016/j.devcel.2011.04.017 1:CAS:528:DC%2BC3MXnsVCns7w%3D
    • Izzi L, Levesque M, Morin S, Laniel D, Wilkes BC, Mille F, Krauss RS, McMahon AP, Allen BL, Charron F (2011) Boc and Gas1 each form distinct Shh receptor complexes with Ptch1 and are required for Shh-mediated cell proliferation. Dev Cell 20:788-801
    • (2011) Dev Cell , vol.20 , pp. 788-801
    • Izzi, L.1    Levesque, M.2    Morin, S.3    Laniel, D.4    Wilkes, B.C.5    Mille, F.6    Krauss, R.S.7    McMahon, A.P.8    Allen, B.L.9    Charron, F.10
  • 32
    • 79958207835 scopus 로고    scopus 로고
    • Overlapping roles and collective requirement for the coreceptors GAS1, CDO, and BOC in SHH pathway function
    • 21664576 10.1016/j.devcel.2011.04.018 1:CAS:528:DC%2BC3MXnsVCns78%3D
    • Allen BL, Song JY, Izzi L, Althaus IW, Kang JS, Charron F, Krauss RS, McMahon AP (2011) Overlapping roles and collective requirement for the coreceptors GAS1, CDO, and BOC in SHH pathway function. Dev Cell 20:775-787
    • (2011) Dev Cell , vol.20 , pp. 775-787
    • Allen, B.L.1    Song, J.Y.2    Izzi, L.3    Althaus, I.W.4    Kang, J.S.5    Charron, F.6    Krauss, R.S.7    McMahon, A.P.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.