Evolution of structure and properties of granules containing microcrystalline cellulose and polyvinylpyrrolidone during high-shear wet granulation

Journal of Pharmaceutical Sciences

Volumn 103, Issue 1, 2014, Pages 207-215

  Osei Yeboah, Frederick ^a   Feng, Yushi ^b   Sun, Changquan Calvin ^a  

^a UNIVERSITY OF MINNESOTA   (United States)

^b ELI LILLY AND COMPANY   (United States)

Author keywords

compaction; excipients; formulation; granulation; mechanical properties; oral drug delivery; particle engineering; powder flow; powder technology; tableting

Indexed keywords

MICROCRYSTALLINE CELLULOSE; POVIDONE;

ARTICLE; DRUG FORMULATION; DRUG GRANULATION; DRUG GRANULE; DRUG STRUCTURE; PARTICLE SIZE; POROSITY; POWDER FLOW; SURFACE PROPERTY; TABLET COMPRESSION; TENSILE STRENGTH;

COMPACTION; EXCIPIENTS; FORMULATION; GRANULATION; MECHANICAL PROPERTIES; ORAL DRUG DELIVERY; PARTICLE ENGINEERING; POWDER FLOW; POWDER TECHNOLOGY; TABLETING;

CELLULOSE; PARTICLE SIZE; POROSITY; POVIDONE; POWDERS; TABLETS; TECHNOLOGY, PHARMACEUTICAL; TENSILE STRENGTH; WATER;

EID: 84890558496     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.23776     Document Type: Article

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