The proinflammatory peptide substance P promotes blood-brain barrier breaching by breast cancer cells through changes in microvascular endothelial cell tight junctions

International Journal of Cancer

Volumn 134, Issue 5, 2014, Pages 1034-1044

  Rodriguez, Pedro L ^a   Jiang, Shuxian ^a   Fu, Yigong ^a   Avraham, Shalom ^a   Avraham, Hava Karsenty ^a  

^a BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

Author keywords

BBB; BMECs; breast tumor metastasis; claudin 5; SP; TJ ZO 1

Indexed keywords

ANGIOPOIETIN 2; CLAUDIN 5; GELATINASE B; PROTEIN ZO1; SPANTIDE; SUBSTANCE P; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL MODEL; ARTICLE; BLOOD BRAIN BARRIER; BREAST CANCER; BREAST METASTASIS; CANCER CELL; CELL ADHESION; CELL CULTURE; CELL MIGRATION; CELL PERMEABILIZATION; COCULTURE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOKINE RELEASE; ELECTRIC RESISTANCE; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MICROVASCULAR ENDOTHELIAL CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN SECRETION; PROTEIN STRUCTURE; PROTEIN TRANSPORT; TIGHT JUNCTION; TUMOR INVASION;

BBB; BMECS; BREAST TUMOR METASTASIS; CLAUDIN-5; SP; TJ ZO-1;

ANIMALS; BLOOD-BRAIN BARRIER; BREAST NEOPLASMS; CELL ADHESION; CELL MOVEMENT; CYTOSKELETON; ENDOTHELIAL CELLS; FEMALE; HUMANS; MICE; MICROVESSELS; PERMEABILITY; SUBSTANCE P; TIGHT JUNCTIONS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84890553647     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.28433     Document Type: Article

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