Age-related and depot-specific changes in white adipose tissue of growth hormone receptor-null mice

Journals of Gerontology - Series A Biological Sciences and Medical Sciences

Volumn 69, Issue 1, 2014, Pages 34-43

  Sackmann Sala, Lucila ^a,c   Berryman, Darlene E ^a,b   Lubbers, Ellen R ^a   Zhang, Han ^a   Vesel, Clare B ^a   Troike, Katie M ^a   Gosney, Elahu S ^a   List, Edward O ^a   Kopchick, John J ^a,b  

^a OHIO UNIVERSITY   (United States)

^b OHIO UNIVERSITY   (United States)

^c INSERM   (France)

Author keywords

Adipose tissue depots; Aging; Endocytosis; Glut4; Growth hormone receptor

Indexed keywords

DNA; GROWTH HORMONE RECEPTOR;

ADIPOCYTE; AGING; ANIMAL; C57BL MOUSE; COMPARATIVE STUDY; CYTOLOGY; DISEASE MODEL; GENE EXPRESSION REGULATION; GENETICS; INSULIN RESISTANCE; MALE; METABOLISM; MOUSE; OBESITY; PHYSIOLOGY; TWO DIMENSIONAL GEL ELECTROPHORESIS; WESTERN BLOTTING; WHITE ADIPOSE TISSUE; ADIPOSE TISSUE DEPOTS; ARTICLE; ENDOCYTOSIS; GLUT4.;

ADIPOCYTES; ADIPOSE TISSUE, WHITE; AGING; ANIMALS; BLOTTING, WESTERN; DISEASE MODELS, ANIMAL; DNA; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; GENE EXPRESSION REGULATION, DEVELOPMENTAL; INSULIN RESISTANCE; MALE; MICE; MICE, INBRED C57BL; OBESITY; RECEPTORS, SOMATOTROPIN;

ADIPOSE TISSUE DEPOTS; AGING; ENDOCYTOSIS; GLUT4.; GROWTH HORMONE RECEPTOR;

EID: 84890545592     PISSN: 10795006     EISSN: 1758535X     Source Type: Journal    
DOI: 10.1093/gerona/glt110     Document Type: Article

References (43)

1. Trayhurn P. Endocrine and signalling role of adipose tissue: new perspectives on fat. Acta Physiol Scand. 2005;184:285-293.
2. Gil A, Olza J, Gil-Campos M, Gomez-Llorente C, Aguilera CM. Is adipose tissue metabolically different at different sites?. Int J Pediatr Obes. 2011;6(suppl 1):13-20.
3. Sepe A, Tchkonia T, Thomou T, Zamboni M, Kirkland JL. Aging and regional differences in fat cell progenitors - a mini-review. Gerontology. 2011;57:66-75.
4. Wronska A, Kmiec Z. Structural and biochemical characteristics of various white adipose tissue depots. Acta Physiol (Oxf). 2012;205:194-208.
5. List EO, Sackmann-Sala L, Berryman DE, et al. Endocrine parameters and phenotypes of the growth hormone receptor gene disrupted (GHR-/-) mouse. Endocr Rev. 2011;32:356-386.
6. Berryman DE, List EO, Sackmann-Sala L, Lubbers E, Munn R, Kopchick JJ. Growth hormone and adipose tissue: beyond the adipocyte. Growth Horm IGF Res. 2011;21:113-123.
7. Masternak MM, Bartke A, Wang F, et al. Metabolic effects of intraabdominal fat in GHRKO mice. Aging Cell. 2012;11:73-81.
8. Sackmann-Sala L, Berryman DE, Munn RD, Lubbers ER, Kopchick JJ. Heterogeneity among white adipose tissue depots in male C57BL/6J mice. Obesity (Silver Spring). 2012;20:101-111.
9. Sackmann-Sala L, Berryman DE, Lubbers ER, et al. Decreased insulin sensitivity and increased oxidative damage in wasting adipose tissue depots of wild-type mice. Age (Dordr). 2012;34:1225-1237.
10. Park SY, Ha BG, Choi GH, et al. EHD2 interacts with the insulinresponsive glucose transporter (GLUT4) in rat adipocytes and may participate in insulin-induced GLUT4 recruitment. Biochemistry. 2004;43:7552-7562.
11. Berryman DE, List EO, Palmer AJ, et al. Two-year body composition analyses of long-lived GHR null mice. J Gerontol A Biol Sci Med Sci. 2010;65:31-40.
12. Coschigano KT, Holland AN, Riders ME, List EO, Flyvbjerg A, Kopchick JJ. Deletion, but not antagonism, of the mouse growth hormone receptor results in severely decreased body weights, insulin, and insulin-like growth factor I levels and increased life span. Endocrinology. 2003;144:3799-3810.
13. Lubbers ER, List EO, Jara A, et al. Adiponectin in mice with altered GH action: links to insulin sensitivity and longevity?. J Endocrinol. 2013;216:363-374.
14. Kaser S, Tatarczyk T, Stadlmayr A, et al. Effect of obesity and insulin sensitivity on adiponectin isoform distribution. Eur J Clin Invest. 2008;38:827-834.
15. Blanpied TA, Scott DB, Ehlers MD. Age-related regulation of dendritic endocytosis associated with altered clathrin dynamics. Neurobiol Aging. 2003;24:1095-1104.
16. Simon-Santamaria J, Malovic I, Warren A, et al. Age-related changes in scavenger receptor-mediated endocytosis in rat liver sinusoidal endothelial cells. J Gerontol A Biol Sci Med Sci. 2010;65:951-960.
17. Guilherme A, Soriano NA, Bose S, et al. EHD2 and the novel EH domain binding protein EHBP1 couple endocytosis to the actin cytoskeleton. J Biol Chem. 2004;279:10593-10605.
18. Morén B, Shah C, Howes MT, et al. EHD2 regulates caveolar dynamics via ATP-driven targeting and oligomerization. Mol Biol Cell. 2012;23:1316-1329.
19. Stoeber M, Stoeck IK, Hänni C, Bleck CK, Balistreri G, Helenius A. Oligomers of the ATPase EHD2 confine caveolae to the plasma membrane through association with actin. EMBO J. 2012;31:2350-2364.
20. Kilgour E, Baldwin SA, Flint DJ. Divergent regulation of rat adipocyte GLUT1 and GLUT4 glucose transporters by GH. J Endocrinol. 1995;145:27-33.
21. Giani JF, Bonkowski MS, Muñoz MC, et al. Insulin signaling cascade in the hearts of long-lived growth hormone receptor knockout mice: effects of calorie restriction. J Gerontol A Biol Sci Med Sci. 2008;63:788-797.
22. Masternak MM, Al-Regaiey KA, Del Rosario Lim MM, et al. Effects of caloric restriction on insulin pathway gene expression in the skeletal muscle and liver of normal and long-lived GHR-KO mice. Exp Gerontol. 2005;40:679-684.
23. Chrétien A, Delaive E, Dieu M, et al. Upregulation of annexin A2 in H(2)O(2)-induced premature senescence as evidenced by 2D-DIGE proteome analysis. Exp Gerontol. 2008;43:353-359.
24. Surette AP, Madureira PA, Phipps KD, Miller VA, Svenningsson P, Waisman DM. Regulation of fibrinolysis by S100A10 in vivo. Blood. 2011;118:3172-3181.
25. Phipps KD, Surette AP, O'Connell PA, Waisman DM. Plasminogen receptor S100A10 is essential for the migration of tumor-promoting macrophages into tumor sites. Cancer Res. 2011;71:6676-6683.
26. Chung L, Nelson AE, Ho KK, Baxter RC. Proteomic profiling of growth hormone-responsive proteins in human peripheral blood leukocytes. J Clin Endocrinol Metab. 2009;94:3038-3043.
27. Andree HA, Stuart MC, Hermens WT, et al. Clustering of lipidbound annexin V may explain its anticoagulant effect. J Biol Chem. 1992;267:17907-17912.
28. Kondo T, Sakaguchi M, Namba M. Two-dimensional gel electrophoretic studies on the cellular aging: accumulation of alpha-2-macroglobulin in human fibroblasts with aging. Exp Gerontol. 2001;36:487-495.
29. Mayot G, Vidal K, Martin JF, et al. Prognostic values of alpha2-macroglobulin, fibrinogen and albumin in regards to mortality and frailty in old rats. Exp Gerontol. 2007;42:498-505.
30. Wagner V, Wagnerová M, Zvára K. Age correlation of alpha- 2-macroglobulin levels in healthy subjects. Physiol Bohemoslov. 1982;31:359-364.
31. Li X, Masliah E, Reixach N, Buxbaum JN. Neuronal production of transthyretin in human and murine Alzheimer's disease: is it protective?. J Neurosci. 2011;31:12483-12490.
32. Reynolds CA, Prince JA, Feuk L, Brookes AJ, Gatz M, Pedersen NL. Longitudinal memory performance during normal aging: twin association models of APOE and other Alzheimer candidate genes. Behav Genet. 2006;36:185-194.
33. Teoh CL, Griffin MD, Howlett GJ. Apolipoproteins and amyloid fibril formation in atherosclerosis. Protein Cell. 2011;2:116-127.
34. Ramella NA, Rimoldi OJ, Prieto ED, et al. Human apolipoprotein A-I-derived amyloid: its association with atherosclerosis. PLoS One. 2011;6:e22532.
35. Campbell GS, Meyer DJ, Raz R, Levy DE, Schwartz J, Carter-Su C. Activation of acute phase response factor (APRF)/Stat3 transcription factor by growth hormone. J Biol Chem. 1995;270:3974-3979.
36. Samadani U, Costa RH. The transcriptional activator hepatocyte nuclear factor 6 regulates liver gene expression. Mol Cell Biol. 1996;16:6273-6284.
37. Ding J, Berryman DE, Jara A, Kopchick JJ. Age- and sex-associated plasma proteomic changes in growth hormone receptor gene-disrupted mice. J Gerontol A Biol Sci Med Sci. 2012;67:830-840.
38. Cartwright MJ, Schlauch K, Lenburg ME, et al. Aging, depot origin, and preadipocyte gene expression. J Gerontol A Biol Sci Med Sci. 2010;65:242-251.
39. Tran TT, Yamamoto Y, Gesta S, Kahn CR. Beneficial effects of subcutaneous fat transplantation on metabolism. Cell Metab. 2008;7:410-420.
40. List EO, Berryman DE, Funk K, et al. The role of GH in adipose tissue: lessons from adipose-specific GH receptor gene-disrupted mice. Mol Endocrinol. 2013;27:524-535.
41. Ikeno Y, Hubbard GB, Lee S, et al. Reduced incidence and delayed occurrence of fatal neoplastic diseases in growth hormone receptor/ binding protein knockout mice. J Gerontol A Biol Sci Med Sci. 2009;64:522-529.
42. Tchkonia T, Morbeck DE, Von Zglinicki T, et al. Fat tissue, aging, and cellular senescence. Aging Cell. 2010;9:667-684.
43. Baker DJ, Wijshake T, Tchkonia T, et al. Clearance of p16Ink4apositive senescent cells delays ageing-associated disorders. Nature. 2011;479:232-236.