Age- and sex-associated plasma proteomic changes in growth hormone receptor gene - Disrupted mice

Journals of Gerontology - Series A Biological Sciences and Medical Sciences

Volumn 67 A, Issue 8, 2012, Pages 830-840

  Ding, Juan ^a   Berryman, Darlene E ^a,b   Jara, Adam ^a   Kopchick, John J ^a  

^a OHIO UNIVERSITY   (United States)

^b School of Applied Health Sciences and Wellness   (United States)

Author keywords

Aging; Growth hormone receptor; Plasma; Proteomics; Sex

Indexed keywords

MUS;

APOLIPOPROTEIN A; APOLIPOPROTEIN A-IV; APOLIPOPROTEIN A4; CARRIER PROTEIN; CYTOKINE; GROWTH HORMONE RECEPTOR; PLASMA RETINOL BINDING PROTEIN; RBP4 PROTEIN, MOUSE; SOMATOTROPIN BINDING PROTEIN; SOMATOTROPIN-BINDING PROTEIN;

AGE; ANIMAL; ARTICLE; BLOOD; BODY COMPOSITION; FEMALE; GENETICS; LONGEVITY; MALE; METABOLISM; MOUSE; PHYSIOLOGY; PROTEOMICS; REAL TIME POLYMERASE CHAIN REACTION; SEX DIFFERENCE;

AGE FACTORS; ANIMALS; APOLIPOPROTEINS A; BODY COMPOSITION; CARRIER PROTEINS; CYTOKINES; FEMALE; LONGEVITY; MALE; MICE; PROTEOMICS; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, SOMATOTROPIN; RETINOL-BINDING PROTEINS, PLASMA; SEX FACTORS;

EID: 84866384631     PISSN: 10795006     EISSN: 1758535X     Source Type: Journal    
DOI: 10.1093/gerona/glr212     Document Type: Article

References (57)

1. Fontana L, Partridge L, Longo VD. Extending healthy life span - from yeast to humans. Science. 2010; 328: 321 - 326.
2. Shimokawa I, Chiba T, Yamaza H, Komatsu T. Longevity genes: insights from calorie restriction and genetic longevity models. Mol Cells. 2008; 26: 427 - 435.
3. Coschigano KT, Holland AN, Riders ME, List EO, Flyvbjerg A, Kopchick JJ. Deletion, but not antagonism, of the mouse growth hormone receptor results in severely decreased body weights, insulin, and insulinlike growth factor I levels and increased life span. Endocrinology. 2003; 144: 3799 - 3810.
4. Berryman DE, List EO, Coschigano KT, Behar K, Kim JK, Kopchick JJ. Comparing adiposity profi les in three mouse models with altered GH signaling. Growth Horm IGF Res. 2004; 14: 309 - 318.
5. Berryman DE, List EO, Palmer AJ, et al. Two-year body composition analyses of long-lived GHR null mice. J Gerontol A Biol Sci Med Sci. 2010; 65: 31 - 40.
6. Liu JL, Coschigano KT, Robertson K, et al. Disruption of growth hormone receptor gene causes diminished pancreatic islet size and increased insulin sensitivity in mice. Am J Physiol Endocrinol Metab. 2004; 287: E405 - E413.
7. Thorner MO. Statement by the Growth Hormone Research Society on the GH/IGF-I axis in extending health span. J Gerontol A Biol Sci Med Sci. 2009; 64: 1039 - 1044.
8. Kinney BA, Coschigano KT, Kopchick JJ, Steger RW, Bartke A. Evidence that age-induced decline in memory retention is delayed in growth hormone resistant GH-R-KO (Laron) mice. Physiol Behav. 2001; 72: 653 - 660.
9. Bellush LL, Doublier S, Holland AN, Striker LJ, Striker GE, Kopchick JJ. Protection against diabetes-induced nephropathy in growth hormone receptor/binding protein gene-disrupted mice. Endocrinology. 2000; 141: 163 - 168.
10. Ikeno Y, Hubbard GB, Lee S, et al. Reduced incidence and delayed occurrence of fatal neoplastic diseases in growth hormone receptor/ binding protein knockout mice. J Gerontol A Biol Sci Med Sci. 2009; 64: 522 - 529.
11. Miller RA, Chang Y, Galecki AT, Al-Regaiey K, Kopchick JJ, Bartke A. Gene expression patterns in calorically restricted mice: partial overlap with long-lived mutant mice. Mol Endocrinol. 2002; 16: 2657 - 2666.
12. Bonkowski MS, Dominici FP, Arum O, et al. Disruption of growth hormone receptor prevents calorie restriction from improving insulin action and longevity. PLoS One. 2009; 4: e4567.
13. Gesing A, Masternak MM, Wang F, et al. Expression of key regulators of mitochondrial biogenesis in growth hormone receptor knockout (GHRKO) mice is enhanced but is not further improved by other potential life-extending interventions. J Gerontol A Biol Sci Med Sci. 2011; 66: 1062 - 1076.
14. Laron Z, Kowadlo-Silbergeld A, Eshet R, Pertzelan A. Growth hormone resistance. Ann Clin Res. 1980; 12: 269 - 277.
15. Guevara-Aguirre J, Balasubramanian P, Guevara-Aguirre M, et al. Growth hormone receptor defi ciency is associated with a major reduction in pro-aging signaling, cancer, and diabetes in humans. Sci Transl Med. 2011; 3: 70ra13.
16. Steuerman R, Shevah O, Laron Z. Congenital IGF1 defi ciency tends to confer protection against post-natal development of malignancies. Eur J Endocrinol. 2011; 164: 485 - 489.
17. List EO, Sackmann-Sala L, Berryman DE, et al. Endocrine parameters and phenotypes of the growth hormone receptor gene disrupted (GHR-/-) mouse. Endocr Rev. 2011; 32: 356 - 386.
18. Baudet ML, Hassanali Z, Sawicki G, List EO, Kopchick JJ, Harvey S. Growth hormone action in the developing neural retina: a proteomic analysis. Proteomics. 2008; 8: 389 - 401.
19. Zhou Y, Xu BC, Maheshwari HG, et al. A mammalian model for Laron syndrome produced by targeted disruption of the mouse growth hormone receptor/binding protein gene (the Laron†‰ mouse). Proc Natl Acad Sci U S A. 1997; 94: 13215 - 13220.
20. Miller RA, Nadon NL. Principles of animal use for gerontological research. J Gerontol A Biol Sci Med Sci. 2000; 55: B117 - B123.
21. Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem. 1976; 72: 248 - 254.
22. Ding J, Kopchick JJ. Plasma biomarkers of mouse aging. Age (Dordr). 2010; 33: 291 - 307.
23. Ding J, Berryman DE, Kopchick JJ. Plasma proteomic profi les of bovine growth hormone transgenic mice as they age. Transgenic Res. 2011; 20:1305e1320.
24. Berryman DE, List EO, Kohn DT, Coschigano KT, Seeley RJ, Kopchick JJ. Effect of growth hormone on susceptibility to diet-induced obesity. Endocrinology. 2006; 147: 2801 - 2808.
25. Egecioglu E, Bjursell M, Ljungberg A, et al. Growth hormone receptor defi ciency results in blunted ghrelin feeding response, obesity and hypolipidemia in mice. Am J Physiol Endocrinol Metab. 2005; 292: E1418 - E1425.
26. Masternak MM, Al-Regaiey KA, Del Rosario Lim MM, et al. Caloric restriction results in decreased expression of peroxisome proliferatoractivated receptor superfamily in muscle of normal and long-lived growth hormone receptor/binding protein knockout mice. J Gerontol A Biol Sci Med Sci. 2005; 60: 1238 - 1245.
27. Wong W-MR, Gerry AB, Putt W, et al. Common variants of apolipoprotein A-IV differ in their ability to inhibit low density lipoprotein oxidation. Atherosclerosis. 2007; 192: 266 - 274.
28. Recalde D, Ostos MA, Badell E, et al. Human apolipoprotein A-IV reduces secretion of proinfl ammatory cytokines and atherosclerotic effects of a chronic infection mimicked by lipopolysaccharide. Arterioscler Thromb Vasc Biol. 2004; 24: 756 - 761.
29. Duverger N, Tremp G, Caillaud JM, et al. Protection against atherogenesis in mice mediated by human apolipoprotein A-IV. Science. 1996; 273: 966 - 968.
30. Araki S, Okazaki M, Goto S. Impaired lipid metabolism in aged mice as revealed by fasting-induced expression of apolipoprotein mRNAs in the liver and changes in serum lipids. Gerontology. 2004; 50: 206 - 215.
31. Warner MM, Guo J, Zhao Y. The relationship between plasma apolipoprotein A-IV levels and coronary heart disease. Chin Med J (Engl). 2001; 114: 275 - 279.
32. Omori M, Watanabe M, Matsumoto K, Honda H, Hattori H, Akizawa T. Impact of serum apolipoprotein A-IV as a marker of cardiovascular disease in maintenance hemodialysis patients. Ther Apher Dial. 2010; 14: 341 - 348.
33. Ding J, List EO, Bower B, Kopchick J. Differential effects of growth hormone versus insulin-like growth factor-I on the mouse plasma proteome. Endocrinology. 2011; 152: 3791 - 3802.
34. Nicklas BJ, Cesari M, Penninx BW, et al. Abdominal obesity is an independent risk factor for chronic heart failure in older people. J Am Geriatr Soc. 2006; 54: 413 - 420.
35. Tanko LB, Bagger YZ, Alexandersen P, Larsen PJ, Christiansen C. Peripheral adiposity exhibits an independent dominant antiatherogenic effect in elderly women. Circulation. 2003; 107: 1626 - 1631.
36. Tran TT, Yamamoto Y, Gesta S, Kahn CR. Benefi cial effects of subcutaneous fat transplantation on metabolism. Cell Metab. 2008; 7: 410 - 420.
37. Kloting N, Graham TE, Berndt J, et al. Serum retinol-binding protein is more highly expressed in visceral than in subcutaneous adipose tissue and is a marker of intra-abdominal fat mass. Cell Metab. 2007; 6: 79 - 87.
38. Bajzova M, Kovacikova M, Vitkova M, et al. Retinol-binding protein 4 expression in visceral and subcutaneous fat in human obesity. Physiol Res. 2008; 57: 927 - 934.
39. Yang Q, Graham TE, Mody N, et al. Serum retinol binding protein 4 contributes to insulin resistance in obesity and type 2 diabetes. Nature. 2005; 436: 356 - 362.
40. Rabinowitz D, Klassen GA, Zierler KL. Effect of human growth hormone on muscle and adipose tissue metabolism in the forearm of man. J Clin Invest. 1965; 44: 51 - 61.
41. Bartke A, Brown-Borg H. Life extension in the dwarf mouse. Curr Top Dev Biol. 2004; 63: 189 - 225.
42. Fleck A. Clinical and nutritional aspects of changes in acute-phase proteins during infl ammation. Proc Nutr Soc. 1989; 48: 347 - 354.
43. Dowling DK, Simmons LW. Reactive oxygen species as universal constraints in life-history evolution. Proc Biol Sci. 2009; 276: 1737 - 1745.
44. Bindon C, Czerniecki M, Ruell P, et al. Clearance rates and systemic effects of intravenously administered interleukin 2 (IL-2) containing preparations in human subjects. Br J Cancer. 1983; 47: 123 - 133.
45. Goetzl EJ, Huang MC, Kon J, et al. Gender specifi city of altered human immune cytokine profi les in aging. FASEB J. 2010; 24: 3580 - 3589.
46. Guo Y, Lu Y, Houle D, et al. Pancreatic islet-specifi c expression of an insulin-like growth factor-I transgene compensates islet cell growth in growth hormone receptor gene-defi cient mice. Endocrinology. 2005; 146: 2602 - 2609.
47. Lee DC, Lee JW, Im JA. Association of serum retinol binding protein 4 and insulin resistance in apparently healthy adolescents. Metabolism. 2007; 56: 327 - 331.
48. Promislow DEL. Costs of sexual selection in natural populations of mammals. Proc Biol Sci. 1992; 247: 203 - 210.
49. Yang Y, Kozloski M. Sex differences in age trajectories of physiological dysregulation: infl ammation, metabolic syndrome, and allostatic load. J Gerontol A Biol Sci Med Sci. 2011; 66: 493 - 500.
50. Bonkowski MS, Rocha JS, Masternak MM, Al Regaiey KA, Bartke A. Targeted disruption of growth hormone receptor interferes with the benefi cial actions of calorie restriction. Proc Natl Acad Sci U S A. 2006; 103: 7901 - 7905.
51. Estep PW 3rd, Warner JB, Bulyk ML. Short-term calorie restriction in male mice feminizes gene expression and alters key regulators of conserved aging regulatory pathways. PLoS One. 2009; 4: e5242.
52. Baumgartner RN, Stauber PM, McHugh D, Koehler KM, Garry PJ. Cross-sectional age differences in body composition in persons 60+ years of age. J Gerontol A Biol Sci Med Sci. 1995; 50: M307 - M316.
53. MacLeod JN, Pampori NA, Shapiro BH. Sex differences in the ultradian pattern of plasma growth hormone concentrations in mice. J Endocrinol. 1991; 131: 395 - 399.
54. Meinhardt UJ, Ho KK. Regulation of growth hormone action by gonadal steroids. Endocrinol Metab Clin North Am. 2007; 36: 57 - 73.
55. Waxman DJ, O'Connor C. Growth hormone regulation of sex-dependent liver gene expression. Mol Endocrinol. 2006; 20: 2613 - 2629.
56. Wiwi CA, Waxman DJ. Role of hepatocyte nuclear factors in growth hormone-regulated, sexually dimorphic expression of liver cytochromes P450. Growth Factors. 2004; 22: 79 - 88.
57. Ling G, Sugathan A, Mazor T, Fraenkel E, Waxman DJ. Unbiased, genome-wide in vivo mapping of transcriptional regulatory elements reveals sex differences in chromatin structure associated with sexspecifi c liver gene expression. Mol Cell Biol. 2011; 30: 5531 - 5544.