Transcriptional repression by methylation: Cooperativity between a CpG cluster in the promoter and remote CpG-rich regions

FEBS Letters

Volumn 379, Issue 3, 1996, Pages 251-254

  Hug, Martin ^a   Silke, John ^a   Georgiev, Oleg ^a   Rusconi, Sandro ^a   Schaffner, Water ^a   Matsuo, Koichi ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

Cooperativity; CpG islands; CpG methylation; Transcriptional silencing

Indexed keywords

TRANSCRIPTION FACTOR;

ARTICLE; BINDING SITE; CONTROLLED STUDY; DNA BINDING; DNA METHYLATION; DNA TRANSCRIPTION; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; HELA CELL; HUMAN; HUMAN CELL; PLASMID; PRIORITY JOURNAL; PROMOTER REGION; TATA BOX;

EID: 0030060367     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/0014-5793(95)01521-3     Document Type: Article

References (37)

1. Bird, A. (1995) Trends Genet. 11, 94-100.
2. Busslinger, M., Hurst, J. and Flavell, R.A. (1983) Cell 34, 197-206.
3. Murray, E.J. and Grosveld, F. (1987) EMBO J. 6, 2329-2335.
4. Iguchi-Ariga, S.M.M. and Schaffner, W. (1989) Genes Dev. 3, 612-619.
5. Hergersberg, M. (1991) Experientia 47, 1171-1181.
6. Buschhausen, G., Wittig, B., Graessmann, M. and Graessmann, A. (1987) Proc. Natl. Acad. Sci. USA 84, 1177-1181.
7. Bird, A. (1992) Cell 70, 5-8.
8. Levine, A., Cantoni, G.L. and Razin, A. (1992) Proc. Natl. Acad. Sci. USA 89, 10119-10123.
9. Kass, S.U., Goddard, J.P. and Adams, R.L.P. (1993) Mol. Cell. Biol. 13, 7372-7279.
10. Boyes, J. and Bird, A. (1992) EMBO J. 11, 327-333.
11. Hsieh, C.-L. (1994) Mol. Cell. Biol. 14, 5487-5494.
12. Jost, J.-P. and Hofsteenge, J. (1992) Proc. Natl. Acad. Sci. USA 89, 9499-9503.
13. Levine, A., Yeivin, A., Ben-Asher, E., Aloni, Y. and Razin, A. (1993) J. Biol. Chem. 268, 21754-21759.
14. Meehan, R.R., Lewis, J.D., McKay, S., Kleiner, E.L. and Bird, A.P. (1989) Cell 58, 499-507.
15. Boyes, J. and Bird, A. (1991) Cell 64, 1123-1134.
16. Bird, A.P. (1986) Nature 321, 209-213.
17. Gardiner-Garden, M. and Frommer, M. (1987) J. Mol. Biol. 196, 261-281.
18. Macleod, D., Charlton, J., Mullins, J. and Bird, A.P. (1994) Genes Dev. 8, 2282-2292.
19. Brandeis, M., Franck, D., Keshet, I., Siegfried, Z., Mendelsohn, M., Nemes, A., Temper, V., Razin, A. and Cedar, H. (1994) Nature 371, 435-438.
20. Silke, J., Rother, K.I., Georgiev, O., Schaffner, W. and Matsuo, K. (1995) FEBS Lett. 370, 170-174.
21. Singer-Sam, J. and Riggs, A.D. (1993) in: DNA Methylation: Molecular Biology and Biological Significance (Jost, J.P. and Saluz, H.P., Eds.) pp. 358-384, Birkhäuser, Basel.
22. Stöger, R., Kubicka, P., Liu, C.-G., Kafri, T., Razin, A., Cedar, H. and Barlow, D.P. (1993) Cell 73, 61-71.
23. Choi, Y.-C. and Chae, C.-B. (1991) J. Biol. Chem. 266, 20504-20511.
24. Matsuo, K., Clay, O., Takahashi, T., Silke, J. and Schaffner, W. (1993) Som. Cell Mol. Genet. 19, 543-555.
25. Aissani, B. and Bernardi, G. (1991) Gene 106, 173-183.
26. Aissani, B. and Bernardi, G. (1991) Gene 106, 185-195.
27. Antequera, F. and Bird, A. (1993) Proc. Natl. Acad. Sci. USA 90, 11995-11999.
28. Höller, M., Westin, G., Jiricny, J. and Schaffner, W. (1988) Genes Dev. 2, 1127-1135.
29. Ebina, Y., Takahara, Y., Kishi, F., Nakazawa, A. and Brent, R. (1983) J. Biol. Chem. 258, 13258-13261.
30. Westin, G., Gerster, T., Müller, M.M., Schaffner, G., and Schaffner, W. (1987) Nucleic Acids Res. 15, 6787-6798.
31. Renbaum, P., Abrahamove, D., Fainsod, A., Wilson, G.G., Rottem, S. and Razin, A. (1990) Nucleic Acids Res. 18, 1145-1152.
32. Matsuo, K., Silke, J., Gramatikoff, K. and Schaffner, W. (1994) Nucleic Acids Res. 22, 5354-5359.
33. Antequera, F., Boyes, J. and Bird, A. (1990) Cell 62, 503-514.
34. Radtke, F., Hug, M., Georgiev, O., Matsuo, K. and Schaffner, W. (1996) Biol. Chem. Hoppe-Seyler 377, in press.
35. Furutani, Y., Notake, M., Fukui, T., Ohue, M., Nomura, H., Yamada, M. and Nakamura, S. (1986) Nucleic Aids Res. 14, 3167-3179.
36. Schatt, M., Rusconi, S. and Schaffner, W. (1990) EMBO J. 9, 481-487.
37. Seipel, K., Georgiev, O. and Schaffner, W. (1992) EMBO J. 11, 4961-4968.