A bi-modal function of Wnt signalling directs an FGF activity gradient to spatially regulate neuronal differentiation in the midbrain

Development (Cambridge)

Volumn 141, Issue 1, 2014, Pages 63-72

  Dyer, Carlene ^a   Blanc, Eric ^b   Hanisch, Anja ^c   Roehl, Henry ^d   Otto, Georg W ^e   Yu, Tian ^a   Basson, M A ^a   Knight, Robert ^a  

^a GUY S HOSPITAL   (United Kingdom)

^b KING'S COLLEGE LONDON   (United Kingdom)

^c IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^d UNIVERSITY OF SHEFFIELD   (United Kingdom)

^e UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Chemical genetics; Hairy; Mathematical modelling; Neurogenesis; Sprouty; Zebrafish

Indexed keywords

3 [4 METHYL 2 (2 OXO 3 INDOLINYLMETHYLIDENYL) 3 PYRROLYL]PROPIONIC ACID; FIBROBLAST GROWTH FACTOR; SPROUTY PROTEIN; WNT1 PROTEIN;

ANIMAL CELL; ANTERIOR POSTERIOR AXIS; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; GENE EXPRESSION; MESENCEPHALIC TRIGEMINAL NUCLEUS; MESENCEPHALON; MOUSE; NEGATIVE FEEDBACK; NERVE CELL DIFFERENTIATION; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; PRIORITY JOURNAL; WNT SIGNALING PATHWAY; ZEBRA FISH;

CHEMICAL GENETICS; HAIRY; MATHEMATICAL MODELLING; NEUROGENESIS; SPROUTY; ZEBRAFISH;

ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CELL MOVEMENT; FIBROBLAST GROWTH FACTORS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; MESENCEPHALON; MICE; MICE, KNOCKOUT; NERVE TISSUE PROTEINS; NEURAL STEM CELLS; NEUROGENESIS; WNT SIGNALING PATHWAY; ZEBRAFISH; ZEBRAFISH PROTEINS;

EID: 84890533405     PISSN: 09501991     EISSN: 14779129     Source Type: Journal    
DOI: 10.1242/dev.099507     Document Type: Article

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