In Vitro and in Vivo Safety Evaluation of Biodegradable Self-Assembled Monomethyl Poly (Ethylene Glycol)-Poly (ε-Caprolactone)-Poly (Trimethylene Carbonate) Micelles

Journal of Pharmaceutical Sciences

Volumn 103, Issue 1, 2014, Pages 305-313

  Yang, Xi ^a   Cao, Dan ^a   Wang, Ning ^a   Sun, Lu ^a   Li, Ling ^a   Nie, Shihong ^a   Wu, Qinjie ^a   Liu, Xinyu ^a   Yi, Cheng ^a   Gong, Changyang ^a  

^a SICHUAN UNIVERSITY   (China)

Author keywords

biocompatibility; biodegradable; micelle; MPEG P(CL co TMC); nanotechnology; polymers; self assembly; synthesis; toxicity evaluation

Indexed keywords

COPOLYMER; MACROGOL; MONOMETHYLPOLY(ETHYLENE GLYCOL)POLY(EPSILON CAPROLACTONE)POLY(TRIMETHYLENE CARBONATE)COPOLYMER; ORGANIC SOLVENT; POLY(TRIMETHYLENE CARBONATE); POLYCAPROLACTONE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIODEGRADATION; BLOOD CELL COUNT; BODY WEIGHT; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG SAFETY; DRUG TOLERANCE; FEMALE; GEL PERMEATION CHROMATOGRAPHY; HEMOLYSIS; HISTOPATHOLOGY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INFRARED SPECTROSCOPY; MALE; MICELLE; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PARTICLE SIZE; RABBIT; SYNTHESIS; TOXICITY TESTING; ZETA POTENTIAL;

BIOCOMPATIBILITY; BIODEGRADABLE; MICELLE; MPEG-P(CL-CO-TMC); NANOTECHNOLOGY; POLYMERS; SELF-ASSEMBLY; SYNTHESIS; TOXICITY EVALUATION;

ANIMALS; CAPROATES; CHEMISTRY, PHARMACEUTICAL; DIOXANES; DRUG DELIVERY SYSTEMS; FEMALE; LACTONES; LIPOSOMES; MALE; MICE; MICE, INBRED BALB C; MICELLES; PARTICLE SIZE; POLYETHYLENE GLYCOLS; POLYMERS;

EID: 84890520706     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.23800     Document Type: Article

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