Acute oral toxicity evaluation of biodegradable and pH-sensitive hydrogel based on polycaprolactone, poly(ethylene glycol) and methylacrylic acid (MAA)

Journal of Biomedical Materials Research - Part A

Volumn 84, Issue 3, 2008, Pages 589-597

  Chen, Xian ^a,b   Qian, ZhiYong ^a   Gou, MaLing ^b   Chao, GuoTao ^b   Zhang, YangDe ^c   Gu, YingChun ^b   Huang, MeiJuan ^a   Wang, JiWei ^c   Pan, YiFeng ^c   Wei, YuQuan ^a   Chen, JianPing ^b   Tu, MingJing ^b  

^a SICHUAN UNIVERSITY   (China)

^b SICHUAN UNIVERSITY   (China)

^c CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

Acute oral toxicity evaluation; Biocompatible; Biodegradable; Histopathologic examination; pH sensitive hydrogel

Indexed keywords

BIOCOMPATIBILITY; BIODEGRADABLE POLYMERS; PH EFFECTS; POLYCAPROLACTONE; POLYETHYLENE GLYCOLS; TOXICITY;

ACUTE ORAL TOXICITY EVALUATION; HISTOPATHOLOGIC EXAMINATION; METHYLACRYLIC ACID;

HYDROGELS;

ACRYLIC ACID METHYL ESTER; EOSIN; FREE RADICAL; HEMATOXYLIN; MACROGOL; POLYCAPROLACTONE;

ACUTE TOXICITY; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIODEGRADABILITY; FEMALE; HEART; HISTOPATHOLOGY; HYDROGEL; INFRARED SPECTROSCOPY; INTESTINE; KIDNEY; LIVER; LUNG; MALE; MAXIMUM TOLERATED DOSE; MOUSE; NONHUMAN; PH; POLYMERIZATION; PROTON NUCLEAR MAGNETIC RESONANCE; SPLEEN; STOMACH; TOXICITY TESTING; ULTRAVIOLET RADIATION;

ABSORBABLE IMPLANTS; ADMINISTRATION, ORAL; ANIMALS; FEMALE; HYDROGELS; HYDROGEN-ION CONCENTRATION; MALE; MICE; MICE, INBRED BALB C; ORGAN SPECIFICITY; POLYESTERS; POLYETHYLENE GLYCOLS; POLYMETHACRYLIC ACIDS;

EID: 39049125574     PISSN: 15493296     EISSN: 15524965     Source Type: Journal    
DOI: 10.1002/jbm.a.31350     Document Type: Article

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