Silencing of HIF prolyl-hydroxylase 2 gene in the renal medulla attenuates salt-sensitive hypertension in dahl S rats

American Journal of Hypertension

Volumn 27, Issue 1, 2014, Pages 107-113

  Zhu, Qing ^a   Hu, Junping ^a   Han, Wei Qing ^a,b   Zhang, Fan ^a   Li, Pin Lan ^a   Wang, Zhengchao ^a,c   Li, Ningjun ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^b SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^c FUJIAN NORMAL UNIVERSITY   (China)

Author keywords

Blood pressure; Cyclooxygenase 2; Heme oxygenase 1; Hypertension; Hypoxia inducible factor; Pressure natriuresis; Sodium excretion

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1ALPHA; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE; PROLYL HYDROXYLASE 2; SHORT HAIRPIN RNA; SODIUM; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERIAL PRESSURE; ARTICLE; ATTENUATION; CONTROLLED STUDY; DAHL SALT SENSITIVE RAT; GENE SILENCING; GENE TARGETING; HYPERTENSION; HYPOTHESIS; KIDNEY BLOOD FLOW; KIDNEY MEDULLA; KIDNEY PERFUSION; KIDNEY TUBULE PRESSURE; MALE; NATRIURESIS; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EXTRACTION; SALT INTAKE; SALT LOADING; SODIUM BALANCE; SODIUM EXCRETION; SODIUM URINE LEVEL; TISSUE HOMOGENATE; WESTERN BLOTTING;

BLOOD PRESSURE; CYCLOOXYGENASE 2; HEME OXYGENASE 1; HYPERTENSION; HYPOXIA-INDUCIBLE FACTOR; PRESSURE NATRIURESIS; SODIUM EXCRETION.;

ANIMALS; BLOOD PRESSURE; DISEASE MODELS, ANIMAL; DOWN-REGULATION; GENE SILENCING; GENETIC THERAPY; HYPERTENSION; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; HYPOXIA-INDUCIBLE FACTOR-PROLINE DIOXYGENASES; KIDNEY MEDULLA; MALE; NATRIURESIS; RATS; RATS, INBRED DAHL; RENAL CIRCULATION; RNA, SMALL INTERFERING; SODIUM CHLORIDE, DIETARY; TIME FACTORS; TRANSFECTION;

EID: 84890505292     PISSN: 08957061     EISSN: 19417225     Source Type: Journal    
DOI: 10.1093/ajh/hpt207     Document Type: Article

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