Expression of heme oxygenase-1 in thick ascending loop of Henle attenuates angiotensin II-dependent hypertension

Journal of the American Society of Nephrology

Volumn 23, Issue 5, 2012, Pages 834-841

  Stec, David E ^a   Drummond, Heather A ^a   Gousette, Monette U ^a   Storm, Megan V ^a   Abraham, Nader G ^b   Csongradi, Eva ^a,c  

^a UNIVERSITY OF MISSISSIPPI SCHOOL OF MEDICINE   (United States)

^b MEDICAL COLLEGE OF OHIO   (United States)

^c UNIVERSITY OF DEBRECEN   (Hungary)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); ANGIOTENSIN II; FUROSEMIDE; HEME OXYGENASE 1; INTERLEUKIN 1BETA; OUABAIN; POTASSIUM CHANNEL; RENAL OUTER MEDULLARY POTASSIUM CHANNEL; SODIUM POTASSIUM CHLORIDE COTRANSPORTER; SODIUM PROTON EXCHANGE PROTEIN 3; TAMM HORSFALL GLYCOPROTEIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD PRESSURE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME LOCALIZATION; GENE EXPRESSION; HENLE LOOP; HYPERTENSION; IMMUNOFLUORESCENCE TEST; KIDNEY MEDULLA; MEAN ARTERIAL PRESSURE; MOUSE; NEPHRON; NONHUMAN; OSMOTIC MINIPUMP; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SODIUM ABSORPTION; TRANSGENIC MOUSE; TREATMENT DURATION; WESTERN BLOTTING;

EID: 84860630714     PISSN: 10466673     EISSN: 15333450     Source Type: Journal    
DOI: 10.1681/ASN.2011050455     Document Type: Article

References (34)

1. Zou AP, Billington H, Su N, Cowley AW Jr: Expression and actions of heme oxygenase in the renal medulla of rats. Hypertension 35: 342-347, 2000 (Pubitemid 30054197)
2. da Silva JL, Zand BA, Yang LM, Sabaawy HE, Lianos E, Abraham NG: Heme oxygenase isoform-specific expression and distribution in the rat kidney. Kidney Int 59: 1448-1457, 2001 (Pubitemid 32281234)
3. Li N, Yi F, dos Santos EA, Donley DK, Li PL: Role of renal medullary heme oxygenase in the regulation of pressure natriuresis and arterial blood pressure. Hypertension 49: 148-154, 2007 (Pubitemid 46360354)
4. Sacerdoti D, Escalante B, Abraham NG, McGiff JC, Levere RD, Schwartzman ML: Treatment with tin prevents the development of hypertension in spontaneously hypertensive rats. Science 243: 388-390, 1989 (Pubitemid 19047515)
5. Levere RD, Martasek P, Escalante B, Schwartzman ML, Abraham NG: Effect of heme arginate administration on blood pressure in spontaneously hypertensive rats. J Clin Invest 86: 213-219, 1990 (Pubitemid 20226994)
6. Sabaawy HE, Zhang F, Nguyen X, El Hosseiny A, Nasjletti A, Schwartzman M, Dennery P, Kappas A, Abraham NG: Human heme oxygenase-1 gene transfer lowers blood pressure and promotes growth in spontaneously hypertensive rats. Hypertension 38: 210-215, 2001 (Pubitemid 34224746)
7. Yang L, Quan S, Nasjletti A, Laniado-Schwartzman M, Abraham NG: Heme oxygenase-1 gene expression modulates angiotensin II-induced increase in blood pressure. Hypertension 43: 1221-1226, 2004 (Pubitemid 38691743)
8. Botros FT, Schwartzman ML, Stier CT Jr, Goodman AI, Abraham NG: Increase in heme oxygenase-1 levels ameliorates renovascular hypertension. Kidney Int 68: 2745-2755, 2005 (Pubitemid 43251019)
9. Vera T, Kelsen S, Yanes LL, Reckelhoff JF, Stec DE: HO-1 induction lowers blood pressure and superoxide production in the renal medulla of angiotensin II hypertensive mice. Am J Physiol Regul Integr Comp Physiol 292: R1472-R1478, 2007 (Pubitemid 46557809)
10. Vera T, Kelsen S, StecDE: Kidney-specific induction of heme oxygenase-1 prevents angiotensin II hypertension. Hypertension 52: 660-665, 2008
11. Hoyer JR, Seiler MW: Pathophysiology of Tamm-Horsfall protein. Kidney Int 16: 279-289, 1979 (Pubitemid 10208489)
12. Liu H, Mount DB, Nasjletti A, Wang W: Carbonmonoxide stimulates the apical 70-pS K+ channel of the rat thick ascending limb. J Clin Invest 103: 963-970, 1999 (Pubitemid 29169603)
13. Quan S, Yang L, Shnouda S, Schwartzman ML, Nasjletti A, Goodman AI, Abraham NG: Expression of human heme oxygenase-1 in the thick ascending limb attenuates angiotensin II-mediated increase in oxidative injury. Kidney Int 65: 1628-1639, 2004 (Pubitemid 38591010)
14. Kelsen S, Patel BJ, Parker LB, Vera T, Rimoldi JM, Gadepalli RS, Drummond HA, Stec DE: Heme oxygenase attenuates angiotensin II-mediated superoxide production in cultured mouse thick ascending loop of Henle cells. Am J Physiol Renal Physiol 295: F1158-F1165, 2008
15. Ortiz PA, Garvin JL: Superoxide stimulates NaCl absorption by the thick ascending limb. Am J Physiol Renal Physiol 283: F957-F962, 2002 (Pubitemid 35192462)
16. Juncos R, Garvin JL: Superoxide enhances Na-K-2Cl cotransporter activity in the thick ascending limb. Am J Physiol Renal Physiol 288: F982-F987, 2005 (Pubitemid 40569764)
17. Herrera M, Ortiz PA, Garvin JL: Regulation of thick ascending limb transport: Role of nitric oxide. Am J Physiol Renal Physiol 290: F1279-F1284, 2006 (Pubitemid 43830750)
18. Mori T, Cowley AW Jr: Angiotensin II-NAD(P)H oxidase-stimulated superoxide modifies tubulovascular nitric oxide cross-talk in renal outer medulla. Hypertension 42: 588-593, 2003 (Pubitemid 37237358)
19. Mori T, O'Connor PM, Abe M, Cowley AW Jr: Enhanced superoxide production in renal outer medulla of Dahl salt-sensitive rats reduces nitric oxide tubular-vascular cross-talk. Hypertension 49: 1336-1341, 2007 (Pubitemid 46809377)
20. Aizawa T, Ishizaka N, Taguchi J, Nagai R, Mori I, Tang SS, Ingelfinger JR, Ohno M: Heme oxygenase-1 is upregulated in the kidney of angiotensin II-induced hypertensive rats: Possible role in renoprotection. Hypertension 35: 800-806, 2000 (Pubitemid 30165329)
21. Haugen EN, Croatt AJ, Nath KA: Angiotensin II induces renal oxidant stress in vivo and heme oxygenase-1 in vivo and in vitro. Kidney Int 58: 144-152, 2000 (Pubitemid 30429859)
22. Li P, Jiang H, Yang L, Quan S, Dinocca S, Rodriguez F, Abraham NG, Nasjletti A: Angiotensin II induces carbon monoxide production in the perfused kidney: Relationship to protein kinase C activation. Am J Physiol Renal Physiol 287: F914-F920, 2004 (Pubitemid 39391088)
23. Ares GR, Caceres P, Alvarez-Leefmans FJ, Ortiz PA: cGMP decreases surface NKCC2 levels in the thick ascending limb: Role of phosphodiesterase 2 (PDE2). Am J Physiol Renal Physiol 295: F877-F887, 2008
24. Abraham NG, Quan S, Mieyal PA, Yang L, Burke-Wolin T, Mingone CJ, Goodman AI, Nasjletti A, Wolin MS: Modulation of cGMP by human HO-1 retrovirus gene transfer in pulmonary microvessel endothelial cells. Am J Physiol Lung Cell Mol Physiol 283: L1117-L1124, 2002 (Pubitemid 35204905)
25. Ferreri NR, Escalante BA, Zhao Y, An SJ, McGiff JC: Angiotensin II induces TNF production by the thick ascending limb: Functional implications. Am J Physiol 274: F148-F155, 1998
26. Lerolle N, Bourgeois S, Leviel F, Lebrun G, Paillard M, Houillier P: Angiotensin II inhibits NaCl absorption in the rat medullary thick ascending limb. Am J Physiol Renal Physiol 287: F404-F410, 2004 (Pubitemid 39095953)
27. Silva GB, Garvin JL: Angiotensin II-dependent hypertension increases Na transport-related oxygen consumption by the thick ascending limb. Hypertension 52: 1091-1098, 2008
28. Zbikowska HM, Soukhareva N, Behnam R, Chang R, Drews R, Lubon H, Hammond D, Soukharev S: The use of the uromodulin promoter to target production of recombinant proteins into urine of transgenic animals. Transgenic Res 11: 425-435, 2002 (Pubitemid 35301751)
29. Zbikowska HM, Soukhareva N, Behnam R, Lubon H, Hammond D, Soukharev S: Uromodulin promoter directs high-level expression of biologically active human alpha1-antitrypsin into mouse urine. Biochem J 365: 7-11, 2002 (Pubitemid 34756134)
30. Goodman AI, Quan S, Yang L, Synghal A, Abraham NG: Functional expression of human heme oxygenase-1 gene in renal structure of spontaneously hypertensive rats. Exp Biol Med (Maywood) 228: 454-458, 2003 (Pubitemid 37203659)
31. Stec DE, Davisson RL, Haskell RE, Davidson BL, Sigmund CD: Efficient liver-specific deletion of a floxed human angiotensinogen transgene by adenoviral delivery of Cre recombinase in vivo. J Biol Chem 274: 21285-21290, 1999
32. Stec DE, Flasch A, Roman RJ, White JA: Distribution of cytochrome P-450 4A and 4F isoforms along the nephron in mice. Am J Physiol Renal Physiol 284: F95-F102, 2003 (Pubitemid 35471289)
33. Ecelbarger CA, Kim GH, Knepper MA, Liu J, Tate M, Welling PA, Wade JB: Regulation of potassium channel Kir 1.1 (ROMK) abundance in the thick ascending limb of Henle's loop. J Am Soc Nephrol 12: 10-18, 2001 (Pubitemid 32056784)
34. Yu M, Lopez B, Dos Santos EA, Falck JR, Roman RJ: Effects of 20-HETE on Na+ transport and Na+ -K+ -ATPase activity in the thick ascending loop of Henle. Am J Physiol Regul Integr Comp Physiol 292: R2400-R2405, 2007 (Pubitemid 47080703)