New concepts in endothelin control of sodium balance

Clinical and Experimental Pharmacology and Physiology

Volumn 39, Issue 1, 2012, Pages 104-110

  Nakano, Daisuke ^a   Pollock, David ^b  

^a KAGAWA UNIVERSITY   (Japan)

^b MEDICAL COLLEGE OF GEORGIA   (United States)

Author keywords

Endothelin; Renal medulla; Sodium handling

Indexed keywords

ARGIPRESSIN; CYCLIC GMP DEPENDENT PROTEIN KINASE; DIPEPTIDYL CARBOXYPEPTIDASE; ENDOTHELIN 1; ENDOTHELIN A RECEPTOR; ENDOTHELIN B RECEPTOR; HYPOXIA INDUCIBLE FACTOR 1ALPHA; NEURONAL NITRIC OXIDE SYNTHASE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE INHIBITOR; PHOSPHATIDYLINOSITOL 3 KINASE; SARAFOTOXIN S6C; SODIUM POTASSIUM CHLORIDE COTRANSPORTER;

ARTICLE; BLOOD PRESSURE REGULATION; DAHL SALT SENSITIVE RAT; DIURESIS; DIURETIC ACTIVITY; ENZYME INHIBITION; HORMONE SYNTHESIS; HUMAN; HYPERTENSION; HYPOXIA; KIDNEY BLOOD FLOW; KIDNEY MEDULLA; NATRIURESIS; OSMOLALITY; PROTEIN EXPRESSION; PROTEIN SECRETION; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; SODIUM BALANCE; SODIUM RESTRICTION; SODIUM URINE LEVEL; UPREGULATION; WATER ABSORPTION;

ANIMALS; ENDOTHELIN-1; HUMANS; HYPERTENSION; KIDNEY MEDULLA; NATRIURESIS; RECEPTOR, ENDOTHELIN A; RECEPTOR, ENDOTHELIN B; RENIN-ANGIOTENSIN SYSTEM; SECOND MESSENGER SYSTEMS; SODIUM CHLORIDE, DIETARY; WATER-ELECTROLYTE BALANCE; WATER-ELECTROLYTE IMBALANCE;

EID: 84855167142     PISSN: 03051870     EISSN: 14401681     Source Type: Journal    
DOI: 10.1111/j.1440-1681.2011.05517.x     Document Type: Article

References (78)

1. D'Angelo G, Loria AS, Pollock DM, Pollock JS. Endothelin activation of reactive oxygen species mediates stress-induced pressor response in Dahl salt-sensitive prehypertensive rats. Hypertension 2010; 56: 282-9.
2. Matsumura Y, Kuro T, Kobayashi Y, Umekawa K, Ohashi N, Takaoka M. Protective effect of SM-19712, a novel and potent endothelin converting enzyme inhibitor, on ischemic acute renal failure in rats. Jpn. J. Pharmacol. 2000; 84: 16-24.
3. Martin C, Cameron J, McGrath B. Mechanical and circulating biomarkers in isolated clinic hypertension. Clin. Exp. Pharmacol. Physiol. 2008; 35: 402-8.
4. Dhaun N, Goddard J, Kohan DE, Pollock DM, Schiffrin EL, Webb DJ. Role of endothelin-1 in clinical hypertension: 20 years on. Hypertension 2008; 52: 452-9.
5. 2 abrogates endothelin-induced vasoconstriction in renal outer medullary descending vasa recta of the rat. J. Clin. Invest. 1995; 95: 2734-40.
6. Williams JM, Pollock DM. Contribution of prostanoid tp receptors to the pressor and intrarenal haemodynamic response to endothelin. Clin. Exp. Pharmacol. Physiol. 2006; 33: 253-7.
7. Schneider MP, Inscho EW, Pollock DM. Attenuated vasoconstrictor responses to endothelin in afferent arterioles during a high-salt diet. Am. J. Physiol. Renal Physiol. 2007; 292: F1208-14.
8. B receptor subtypes in the regulation of intrarenal blood flow and oxygen tension in rats. Clin. Exp. Pharmacol. Physiol. 2008; 35: 1227-32.
9. Thai TL, Churchill GC, Arendshorst WJ. NAADP receptors mediate calcium signaling stimulated by endothelin-1 and norepinephrine in renal afferent arterioles. Am. J. Physiol. Renal Physiol. 2009; 297: F510-16.
10. Evans RG, Madden AC, Denton KM. Diversity of responses of renal cortical and medullary blood flow to vasoconstrictors in conscious rabbits. Acta Physiol. Scand. 2000; 169: 297-308.
11. Sullivan JC, Wang B, Boesen EI, D'Angelo G, Pollock JS, Pollock DM. Novel use of ultrasound to examine regional blood flow in the mouse kidney. Am. J. Physiol. Renal Physiol. 2009; 297: F228-35.
12. Morigi M, Buelli S, Zanchi C et al. Shigatoxin-induced endothelin-1 expression in cultured podocytes autocrinally mediates actin remodeling. Am. J. Pathol. 2006; 169: 1965-75.
13. Tahara A, Tsukada J, Tomura Y, Suzuki T, Yatsu T, Shibasaki M. Vasopressin stimulates the production of extracellular matrix by cultured rat mesangial cells. Clin. Exp. Pharmacol. Physiol. 2008; 35: 586-93.
14. Gagliardini E, Corna D, Zoja C et al. Unlike each drug alone, lisinopril if combined with avosentan promotes regression of renal lesions in experimental diabetes. Am. J. Physiol. Renal Physiol. 2009; 297: F1448-56.
15. Saleh MA, Boesen EI, Pollock JS, Savin VJ, Pollock DM. Endothelin-1 increases glomerular permeability and inflammation independent of blood pressure in the rat. Hypertension 2010; 56: 942-9.
16. Romano G, Giagu P, Favret G, Bartoli E. Effect of endothelin 1 on proximal reabsorption and tubuloglomerular feedback. Kidney Blood Press. Res. 2000; 23: 360-5.
17. 2+ exchanger type 1 in renal epithelial cells. J. Cardiovasc. Pharmacol. 2004; 44(Suppl. 1): S239-43.
18. Khanna A, Simoni J, Wesson DE. Endothelin-induced increased aldosterone activity mediates augmented distal nephron acidification as a result of dietary protein. J. Am. Soc. Nephrol. 2005; 16: 1929-35.
19. Grenz A, Klein J, Kohle C et al. Effect of endothelin-1 on erythropoietin production in a rat model under normoxia and functional carbon monoxide-induced hypoxia. Naunyn Schmiedebergs Arch. Pharmacol. 2006; 373: 342-8.
20. Wang Y, Chen AF, Wang DH. ET(A) receptor blockade prevents renal dysfunction in salt-sensitive hypertension induced by sensory denervation. Am. J. Physiol. Heart Circ. Physiol. 2005; 289: H2005-11.
21. Kopp UC, Cicha MZ, Smith LA. Differential effects of endothelin on activation of renal mechanosensory nerves: Stimulatory in high-sodium diet and inhibitory in low-sodium diet. Am. J. Physiol. Regul. Integr. Comp. Physiol. 2006; 291: R1545-56.
22. Terada Y, Tomita K, Nonoguchi H, Marumo F. Different localization of two types of endothelin receptor mRNA in microdissected rat nephron segments using reverse transcription and polymerase chain reaction assay. J. Clin. Invest. 1992; 90: 107-12.
23. Kuc RE, Maguire JJ, Davenport AP. Quantification of endothelin receptor subtypes in peripheral tissues reveals downregulation of ET(A) receptors in ET(B)-deficient mice. Exp. Biol. Med. 2006; 231: 741-5.
24. Takemoto F, Uchida S, Ogata E, Kurokawa K. Endothelin-1 and endothelin-3 binding to rat nephrons. Am. J. Physiol. 1993; 264: F827-32.
25. Karet FE, Davenport AP. Localization of endothelin peptides in human kidney. Kidney Int. 1996; 49: 382-7.
26. Herrera M, Garvin JL. Endothelin stimulates endothelial nitric oxide synthase expression in the thick ascending limb. Am. J. Physiol. Renal Physiol. 2004; 287: F231-5.
27. B receptors produce diuresis and natriuresis via NOS1. Am. J. Physiol. Renal Physiol. 2008; 294: F1205-11.
28. Boesen EI, Sasser JM, Saleh MA et al. Interleukin-1beta, but not interleukin-6, enhances renal and systemic endothelin production in vivo. Am. J. Physiol. Renal Physiol. 2008; 295: F446-53.
29. Schneider MP, Ge Y, Pollock DM, Pollock JS, Kohan DE. Collecting duct-derived endothelin regulates arterial pressure and Na excretion via nitric oxide. Hypertension 2008; 51: 1605-10.
30. Nakano D, Pollock DM. Contribution of endothelin A receptors in endothelin 1-dependent natriuresis in female rats. Hypertension 2009; 53: 324-30.
31. Herrera M, Hong NJ, Ortiz PA, Garvin JL. Endothelin-1 inhibits thick ascending limb transport via Akt-stimulated nitric oxide production. J. Biol. Chem. 2009; 284: 1454-60.
32. Herrera M, Garvin JL. A high-salt diet stimulates thick ascending limb eNOS expression by raising medullary osmolality and increasing release of endothelin-1. Am. J. Physiol. Renal Physiol. 2005; 288: F58-64.
33. Ujiie K, Terada Y, Nonoguchi H, Shinohara M, Tomita K, Marumo F. Messenger RNA expression and synthesis of endothelin-1 along rat nephron segments. J. Clin. Invest. 1992; 90: 1043-8.
34. Kitamura K, Tanaka T, Kato J, Ogawa T, Eto T, Tanaka K. Immunoreactive endothelin in rat kidney inner medulla: Marked decrease in spontaneously hypertensive rats. Biochem. Biophys. Res. Commun. 1989; 162: 38-44.
35. Kohan DE. Endothelin production by human inner medullary collecting duct cells. J. Am. Soc. Nephrol. 1993; 3: 1719-21.
36. Kohan DE, Padilla E. Osmolar regulation of endothelin-1 production by rat inner medullary collecting duct. J. Clin. Invest. 1993; 91: 1235-40.
37. Tomita K, Nonoguchi H, Marumo F. Effects of endothelin on peptide-dependent cyclic adenosine monophosphate accumulation along the nephron segments of the rat. J. Clin. Invest. 1990; 85: 2014-18.
38. Stricklett PK, Hughes AK, Kohan DE. Endothelin-1 stimulates NO production and inhibits cAMP accumulation in rat inner medullary collecting duct through independent pathways. Am. J. Physiol. Renal Physiol. 2006; 290: F1315-19.
39. Tomita K, Nonoguchi H, Terada Y, Marumo F. Effects of ET-1 on water and chloride transport in cortical collecting ducts of the rat. Am. J. Physiol. 1993; 264: F690-6.
40. Oishi R, Nonoguchi H, Tomita K, Marumo F. Endothelin-1 inhibits AVP-stimulated osmotic water permeability in rat inner medullary collecting duct. Am. J. Physiol. 1991; 261: F951-6.
41. + channel by endothelin-1 in rat collecting duct. Am. J. Physiol. Renal Physiol. 2008; 295: F1063-70.
42. Ahn D, Ge Y, Stricklett PK et al. Collecting duct-specific knockout of endothelin-1 causes hypertension and sodium retention. J. Clin. Invest. 2004; 114: 504-11.
43. Ge Y, Bagnall A, Stricklett PK et al. Collecting duct-specific knockout of the endothelin B receptor causes hypertension and sodium retention. Am. J. Physiol. Renal Physiol. 2006; 291: F1274-80.
44. Modesti PA, Cecioni I, Migliorini A et al. Increased renal endothelin formation is associated with sodium retention and increased free water clearance. Am. J. Physiol. 1998; 275: H1070-7.
45. Vanni S, Polidori G, Cecioni I, Serni S, Carini M, Modesti PA. ET(B) receptor in renal medulla is enhanced by local sodium during low salt intake. Hypertension 2002; 40: 179-85.
46. 2 accumulation in rat IMCD. Am. J. Physiol. 1993; 265: F670-6.
47. Ge Y, Stricklett PK, Hughes AK, Yanagisawa M, Kohan DE. Collecting duct-specific knockout of the endothelin A receptor alters renal vasopressin responsiveness, but not sodium excretion or blood pressure. Am. J. Physiol. Renal Physiol. 2005; 289: F692-8.
48. Ge Y, Bagnall A, Stricklett PK, Webb D, Kotelevtsev Y, Kohan DE. Combined knockout of collecting duct endothelin A and B receptors causes hypertension and sodium retention. Am. J. Physiol. Renal Physiol. 2008; 295: F1635-40.
49. Ge Y, Ahn D, Stricklett PK et al. Collecting duct-specific knockout of endothelin-1 alters vasopressin regulation of urine osmolality. Am. J. Physiol. Renal Physiol. 2005; 288: F912-20.
50. Mori T, Ogawa S, Cowley AJ, Ito S. Role of renal medullary oxidative/carbonyl stress in salt sensitive hypertension and diabetes. Clin. Exp. Pharmacol. Physiol. 2012; 39: 125-31.
51. Pallone TL, Silldorff EP. Pericyte regulation of renal medullary blood flow. Exp. Nephrol. 2001; 9: 165-70.
52. Liss P, Carlsson PO, Nygren A, Palm F, Hansell P. Et-A receptor antagonist BQ123 prevents radiocontrast media-induced renal medullary hypoxia. Acta Radiol. 2003; 44: 111-17.
53. B receptors in mediating the diuretic response to intramedullary hyperosmotic NaCl infusion. Am. J. Physiol. Renal Physiol. 2010; 299: F1424-32.
54. Yang T, Terada Y, Nonoguchi H, Ujiie K, Tomita K, Marumo F. Effect of hyperosmolality on production and mRNA expression of ET-1 in inner medullary collecting duct. Am. J. Physiol. 1993; 264: F684-9.
55. Boesen EI, Pollock DM. Acute increases of renal medullary osmolality stimulate endothelin release from the kidney. Am. J. Physiol. Renal Physiol. 2007; 292: F185-91.
56. Todd-Turla KM, Zhu XL, Shu X et al. Synthesis and secretion of endothelin in a cortical collecting duct cell line. Am. J. Physiol. 1996; 271: F330-9.
57. Hale TM, Bushfield TL, Woolard J, Pang JJ, Rees-Milton KJ, Adams MA. Changes critical to persistent lowering of arterial pressure in spontaneously hypertensive rat occur early in antihypertensive treatment. J. Hypertens. 2011; 29: 113-22.
58. Wong WH, Wong BP, Wong EF, Huang MH, Wong NL. Downregulation of endothelin B receptors in cardiomyopathic hamsters. Cardiology 1998; 89: 195-201.
59. Wong NL, Tsui JK. Angiotensin regulates endothelin-B receptor in rat inner medullary collecting duct. Metabolism 2001; 50: 661-6.
60. Kittikulsuth W, Pollock JS, Pollock DM. Angiotensin II. hypertension reduces endothelin receptor binding in the renal medulla. Hypertension 2010; 56: E165.
61. Kittikulsuth W, Boesen EI, Pollock DM. Natriuretic response to renal medullary endothelin B receptor activation is blunted in chronic angiotensin II-infused rats. FASEB J. 2009; 23(Suppl.): LB145. (Abstract).
62. Kujal P, Chabova VC, Vernerova Z et al. Similar renoprotection after renin-angiotensin-dependent and -independent antihypertensive therapy in 5/6-nephrectomized Ren-2 transgenic rats: Are there blood pressure-independent effects? Clin. Exp. Pharmacol. Physiol. 2010; 37: 1159-69.
63. Kobori H, Urushihara M, Xu JH, Berenson GS, Navar LG. Urinary angiotensinogen is correlated with blood pressure in men (Bogalusa Heart Study). J. Hypertens. 2010; 28: 1422-8.
64. Fan YY, Kohno M, Nakano D et al. Inhibitory effects of a dihydropyridine calcium channel blocker on renal injury in aldosterone-infused rats. J. Hypertens. 2009; 27: 1855-62.
65. Fan YY, Kohno M, Nakano D et al. Cilnidipine suppresses podocyte injury and proteinuria in metabolic syndrome rats: Possible involvement of N-type calcium channel in podocyte. J. Hypertens. 2010; 28: 1034-43.
66. Wong S, Brennan FE, Young MJ, Fuller PJ, Cole TJ. A direct effect of aldosterone on endothelin-1 gene expression in vivo. Endocrinology 2007; 148: 1511-17.
67. Stow LR, Gumz ML, Lynch IJ et al. Aldosterone modulates steroid receptor binding to the endothelin-1 gene (edn1). J. Biol. Chem. 2009; 284: 30.
68. Luther JM, Wang Z, Ma J, Makhanova N, Kim HS, Brown NJ. Endogenous aldosterone contributes to acute angiotensin II-stimulated plasminogen activator inhibitor-1 and preproendothelin-1 expression in heart but not aorta. Endocrinology 2009; 150: 2229-36.
69. Prieto-Carrasquero MC, Botros FT, Pagan J et al. Collecting duct renin is upregulated in both kidneys of 2-kidney, 1-clip goldblatt hypertensive rats. Hypertension 2008; 51: 1590-6.
70. Prokai A, Peti-Peterdi J. Recent advances in tissue (pro)renin imaging. Front. Biosci. 2010; 2: 1227-33.
71. Miller RL, Kohan DE. Hypoxia regulates endothelin-1 production by the inner medullary collecting duct. J. Lab. Clin. Med. 1998; 131: 45-8.
72. Nir A, Clavell AL, Heublein D, Aarhus LL, Burnett JC Jr. Acute hypoxia and endogenous renal endothelin. J. Am. Soc. Nephrol. 1994; 4: 1920-4.
73. Knowles HJ, Tian YM, Mole DR, Harris AL. Novel mechanism of action for hydralazine: Induction of hypoxia-inducible factor-1alpha, vascular endothelial growth factor, and angiogenesis by inhibition of prolyl hydroxylases. Circ. Res. 2004; 95: 162-9.
74. Li N, Chen L, Yi F, Xia M, Li PL. Salt-sensitive hypertension induced by decoy of transcription factor hypoxia-inducible factor-1alpha in the renal medulla. Circ. Res. 2008; 102: 1101-8.
75. Ikeda T, Ohta H, Okada M et al. Pathophysiological roles of endothelin-1 in Dahl salt-sensitive hypertension. Hypertension 1999; 34: 514-19.
76. Hsieh TJ, Lin SR, Lee YJ et al. Increased renal medullary endothelin-1 synthesis in prehypertensive DOCA- and salt-treated rats. Am. J. Physiol. Renal Physiol. 2000; 279: F112-21.
77. Matsumura Y, Kuro T, Konishi F, Takaoka M, Gariepy CE, Yanagisawa M. Enhanced blood pressure sensitivity to DOCA-salt treatment in endothelin ET(B) receptor-deficient rats. Br. J. Pharmacol. 2000; 129: 1060-2.
78. B receptor in gender differences in deoxycorticosterone acetate-salt-induced hypertension. Clin. Exp. Pharmacol. Physiol. 2007; 34: 280-5.