메뉴 건너뛰기




Volumn 12, Issue 12, 2013, Pages 2874-2884

Tunicamycin potentiates cisplatin anticancer efficacy through the dpagt1/akt/abcg2 pathway in mouse xenograft models of human hepatocellular carcinoma

Author keywords

[No Author keywords available]

Indexed keywords

BREAST CANCER RESISTANCE PROTEIN; CD133 ANTIGEN; CISPLATIN; CYCLINE; DOXORUBICIN; PROTEIN KINASE B; TUNICAMYCIN; UDP GLCNAC DOLICHOL PHOSPHATE N ACETYLGLUCOSAMINE 1 PHOSPHATE TRANSFERASE; UNCLASSIFIED DRUG; URIDINE DIPHOSPHATE N ACETYLGLUCOSAMINE; VINCRISTINE;

EID: 84890492751     PISSN: 15357163     EISSN: 15388514     Source Type: Journal    
DOI: 10.1158/1535-7163.MCT-13-0201     Document Type: Article
Times cited : (52)

References (45)
  • 1
    • 0036364467 scopus 로고    scopus 로고
    • Multidrug resistance in cancer: Role of ATP-dependent transporters
    • Gottesman MM, Fojo T, Bates SE. Multidrug resistance in cancer: role of ATP-dependent transporters. Nat Rev Cancer 2002;2:48-58.
    • (2002) Nat Rev Cancer , vol.2 , pp. 48-58
    • Gottesman, M.M.1    Fojo, T.2    Bates, S.E.3
  • 2
    • 84856501335 scopus 로고    scopus 로고
    • The developing cancer stem-cell model: Clinical challenges and opportunities
    • Vermeulen L, de Sousa EMF, Richel DJ, Medema JP. The developing cancer stem-cell model: Clinical challenges and opportunities. Lancet Oncol 2012;13:e83-9.
    • (2012) Lancet Oncol , vol.13
    • Vermeulen, L.1    De Sousa, E.M.F.2    Richel, D.J.3    Medema, J.P.4
  • 4
    • 79960006754 scopus 로고    scopus 로고
    • CD24(+) liver tumor-initiating cells drive self-renewal and tumor initiation through STAT3-mediated NANOG regulation
    • Lee TK, Castilho A, Cheung VC, Tang KH, Ma S, Ng IO. CD24(+) liver tumor-initiating cells drive self-renewal and tumor initiation through STAT3-mediated NANOG regulation. Cell Stem Cell 2011; 9:50-63
    • (2011) Cell Stem Cell , vol.9 , pp. 50-63
    • Lee, T.K.1    Castilho, A.2    Cheung, V.C.3    Tang, K.H.4    Ma, S.5    Ng, I.O.6
  • 5
    • 84865203983 scopus 로고    scopus 로고
    • A restricted cell population propagates glioblastoma growth after chemotherapy
    • Chen J, Li Y, Yu TS, McKay RM, Burns DK, Kernie SG, et al. A restricted cell population propagates glioblastoma growth after chemotherapy. Nature 2012;488:522-6.
    • (2012) Nature , vol.488 , pp. 522-526
    • Chen, J.1    Li, Y.2    Yu, T.S.3    Mckay, R.M.4    Burns, D.K.5    Kernie, S.G.6
  • 6
    • 33847686753 scopus 로고    scopus 로고
    • CD133 positive hepatocellular carcinoma cells possess high capacity for tumorigenicity
    • Yin S, Li J, Hu C, Chen X, Yao M, Yan M, et al. CD133 positive hepatocellular carcinoma cells possess high capacity for tumorigenicity. Int J Cancer 2007;120:1444-50.
    • (2007) Int J Cancer , vol.120 , pp. 1444-1450
    • Yin, S.1    Li, J.2    Hu, C.3    Chen, X.4    Yao, M.5    Yan, M.6
  • 8
    • 34250903640 scopus 로고    scopus 로고
    • Histological and culture studies with respect to ABCG2 expression support the existence of a cancer cell hierarchy in human hepatocellular carcinoma
    • Zen Y, Fujii T, Yoshikawa S, Takamura H, Tani T, Ohta T, et al. Histological and culture studies with respect to ABCG2 expression support the existence of a cancer cell hierarchy in human hepatocellular carcinoma. Am J Pathol 2007;170:1750-62.
    • (2007) Am J Pathol , vol.170 , pp. 1750-1762
    • Zen, Y.1    Fujii, T.2    Yoshikawa, S.3    Takamura, H.4    Tani, T.5    Ohta, T.6
  • 9
    • 0034795256 scopus 로고    scopus 로고
    • The ABC transporter Bcrp1/ABCG2 is expressed in a wide varietyof stem cells and is a molecular determinant of the side-population phenotype
    • Zhou S, Schuetz JD, Bunting KD, Colapietro AM,Sampath J, Morris JJ, et al. The ABC transporter Bcrp1/ABCG2 is expressed in a wide varietyof stem cells and is a molecular determinant of the side-population phenotype. Nat Med 2001;7:1028-34.
    • (2001) Nat Med , vol.7 , pp. 1028-1034
    • Zhou, S.1    Schuetz, J.D.2    Bunting, K.D.3    Colapietro, A.M.4    Sampath, J.5    Morris, J.J.6
  • 11
    • 34548253014 scopus 로고    scopus 로고
    • Maintenance of retinal stem cells by ABCG2 is regulated by notch signaling
    • Bhattacharya S, Das A, Mallya K, Ahmad I. Maintenance of retinal stem cells by ABCG2 is regulated by notch signaling. J Cell Sci 2007; 120:2652-62.
    • (2007) J Cell Sci , vol.120 , pp. 2652-2662
    • Bhattacharya, S.1    Das, A.2    Mallya, K.3    Ahmad, I.4
  • 12
    • 33745953739 scopus 로고    scopus 로고
    • Complex interaction of bcrp/abcg2 and imatinib in bcr-abl-expressing cells: Bcrpmediated resistance to imatinib is attenuated by imatinib-induced reduction of bcrp expression
    • Nakanishi T, Shiozawa K, Hassel BA, Ross DD. Complex interaction of BCRP/ABCG2 and imatinib in BCR-ABL-expressing cells: BCRPmediated resistance to imatinib is attenuated by imatinib-induced reduction of BCRP expression. Blood 2006;108:678-84.
    • (2006) Blood , vol.108 , pp. 678-684
    • Nakanishi, T.1    Shiozawa, K.2    Hassel, B.A.3    Ross, D.D.4
  • 13
    • 78751552761 scopus 로고    scopus 로고
    • Lupeol targets liver tumor-initiating cells through phosphatase and tensin homolog modulation
    • Lee TK, Castilho A, Cheung VC, Tang KH, Ma S, Ng IO. Lupeol targets liver tumor-initiating cells through phosphatase and tensin homolog modulation. Hepatology 2011;53:160-70.
    • (2011) Hepatology , vol.53 , pp. 160-170
    • Lee, T.K.1    Castilho, A.2    Cheung, V.C.3    Tang, K.H.4    Ma, S.5    Ng, I.O.6
  • 14
    • 60849117508 scopus 로고    scopus 로고
    • Pten/pi3k/akt pathway regulates the side population phenotype and abcg2 activity in glioma tumor stem-like cells
    • Bleau AM, Hambardzumyan D, Ozawa T, Fomchenko EI, Huse JT, Brennan CW, et al. PTEN/PI3K/Akt pathway regulates the side population phenotype and ABCG2 activity in glioma tumor stem-like cells.Cell Stem Cell 2009;4:226-35
    • (2009) Cell Stem Cell , vol.4 , pp. 226-235
    • Bleau, A.M.1    Hambardzumyan, D.2    Ozawa, T.3    Fomchenko, E.I.4    Huse, J.T.5    Brennan, C.W.6
  • 15
    • 57349094741 scopus 로고    scopus 로고
    • Analysis ofabcg2expression and side population identifies intrinsic drug efflux in the hcc cell line mhcc-97l and its modulation by akt signaling
    • HuC, Li H, Li J, Zhu Z, Yin S,Hao X, et al. Analysis ofABCG2expression and side population identifies intrinsic drug efflux in the HCC cell line MHCC-97L and its modulation by Akt signaling. Carcinogenesis 2008;29:2289-97.
    • (2008) Carcinogenesis , vol.29 , pp. 2289-2297
    • Hu, C.1    Li, H.2    Li, J.3    Zhu, Z.4    Yin, S.5    Hao, X.6
  • 16
    • 0034657712 scopus 로고    scopus 로고
    • Role of N-oligosaccharide endoplasmic reticulum processing reactions in glycoprotein folding and degradation
    • Parodi AJ. Role of N-oligosaccharide endoplasmic reticulum processing reactions in glycoprotein folding and degradation. Biochem J 2000;348:1-13.
    • (2000) Biochem J , vol.348 , pp. 1-13
    • Parodi, A.J.1
  • 17
    • 71949113235 scopus 로고    scopus 로고
    • Disruption of n-linked glycosylation enhances ubiquitinmediated proteasomal degradation of the human atp-binding cassette transporter abcg2
    • Nakagawa H, Wakabayashi-Nakao K, Tamura A, Toyoda Y, Koshiba S, Ishikawa T. Disruption of N-linked glycosylation enhances ubiquitinmediated proteasomal degradation of the human ATP-binding cassette transporter ABCG2. FEBS J 2009;276:7237-52.
    • (2009) FEBS J , vol.276 , pp. 7237-7252
    • Nakagawa, H.1    Wakabayashi-Nakao, K.2    Tamura, A.3    Toyoda, Y.4    Koshiba, S.5    Ishikawa, T.6
  • 18
    • 80051698302 scopus 로고    scopus 로고
    • Unfolded protein response is required in nu/nu mice microvasculature for treating breast tumor with tunicamycin
    • Banerjee A, Lang JY, Hung MC, Sengupta K, Banerjee SK, Baksi K, et al. Unfolded protein response is required in nu/nu mice microvasculature for treating breast tumor with tunicamycin. J Biol Chem 2011;286:29127-38.
    • (2011) J Biol Chem , vol.286 , pp. 29127-29138
    • Banerjee, A.1    Lang, J.Y.2    Hung, M.C.3    Sengupta, K.4    Banerjee, S.K.5    Baksi, K.6
  • 20
    • 22244472001 scopus 로고    scopus 로고
    • Tunicamycin enhances tumor necrosis factor-related apoptosisinducing ligand-induced apoptosis in human prostate cancer cells
    • Shiraishi T, Yoshida T, Nakata S, Horinaka M, Wakada M, Mizutani Y, et al. Tunicamycin enhances tumor necrosis factor-related apoptosisinducing ligand-induced apoptosis in human prostate cancer cells. Cancer Res 2005;65:6364-70.
    • (2005) Cancer Res , vol.65 , pp. 6364-6370
    • Shiraishi, T.1    Yoshida, T.2    Nakata, S.3    Horinaka, M.4    Wakada, M.5    Mizutani, Y.6
  • 21
    • 34547487284 scopus 로고    scopus 로고
    • Combination of tunicamycin with anticancer drugs synergistically enhances their toxicity in multidrugresistant human ovarian cystadenocarcinoma cells
    • Hiss DC, Gabriels GA, Folb PI. Combination of tunicamycin with anticancer drugs synergistically enhances their toxicity in multidrugresistant human ovarian cystadenocarcinoma cells. Cancer Cell Int 2007;7:5.
    • (2007) Cancer Cell Int , vol.7 , pp. 5
    • Hiss, D.C.1    Gabriels, G.A.2    Folb, P.I.3
  • 22
    • 0029128356 scopus 로고
    • Inhibitors of carbohydrate processing: A new class of anticancer agents
    • Goss PE, Baker MA, Carver JP, Dennis JW. Inhibitors of carbohydrate processing: A new class of anticancer agents. Clin Cancer Res 1995; 1:935-44.
    • (1995) Clin Cancer Res , vol.1 , pp. 935-944
    • Goss, P.E.1    Baker, M.A.2    Carver, J.P.3    Dennis, J.W.4
  • 23
    • 80052505362 scopus 로고    scopus 로고
    • Increased antitumor efficacy by the combined administration of swainsonine and cisplatin in vivo
    • Santos FM, Latorre AO, Hueza IM, Sanches DS, Lippi LL, Gardner DR, et al. Increased antitumor efficacy by the combined administration of swainsonine and cisplatin in vivo. Phytomedicine 2011; 18:1096-101.
    • (2011) Phytomedicine , vol.18 , pp. 1096-1101
    • Santos, F.M.1    Latorre, A.O.2    Hueza, I.M.3    Sanches, D.S.4    Lippi, L.L.5    Gardner, D.R.6
  • 24
    • 36749078674 scopus 로고    scopus 로고
    • Under normoxia, 2-deoxy-d-glucose elicits cell death in select tumor types not by inhibition of glycolysis but by interfering with nlinked glycosylation
    • Kurtoglu M, Gao N, Shang J, Maher JC, Lehrman MA, Wangpaichitr M, et al. Under normoxia, 2-deoxy-D-glucose elicits cell death in select tumor types not by inhibition of glycolysis but by interfering with Nlinked glycosylation. Mol Cancer Ther 2007;6:3049-58.
    • (2007) Mol Cancer Ther , vol.6 , pp. 3049-3058
    • Kurtoglu, M.1    Gao, N.2    Shang, J.3    Maher, J.C.4    Lehrman, M.A.5    Wangpaichitr, M.6
  • 25
    • 1642494855 scopus 로고    scopus 로고
    • 2-deoxy-D-glucose increases the efficacy of adriamycin and paclitaxel in human osteosarcoma and non-small cell lung cancers in vivo
    • Maschek G, Savaraj N, Priebe W, Braunschweiger P, Hamilton K, Tidmarsh GF, et al. 2-deoxy-D-glucose increases the efficacy of adriamycin and paclitaxel in human osteosarcoma and non-small cell lung cancers in vivo. Cancer Res 2004;64:31-4.
    • (2004) Cancer Res , vol.64 , pp. 31-34
    • Maschek, G.1    Savaraj, N.2    Priebe, W.3    Braunschweiger, P.4    Hamilton, K.5    Tidmarsh, G.F.6
  • 26
    • 80052015345 scopus 로고    scopus 로고
    • Hypoxia-inducible factor 1 alpha-activated angiopoietin-like protein 4 contributes to tumor metastasis via vascular cell adhesion molecule-1/integrin beta1 signaling in human hepatocellular carcinoma
    • Li H, Ge C, Zhao F, Yan M, Hu C, Jia D, et al. Hypoxia-inducible factor 1 alpha-activated angiopoietin-like protein 4 contributes to tumor metastasis via vascular cell adhesion molecule-1/integrin beta1 signaling in human hepatocellular carcinoma. Hepatology 2011;54:910-9.
    • (2011) Hepatology , vol.54 , pp. 910-919
    • Li, H.1    Ge, C.2    Zhao, F.3    Yan, M.4    Hu, C.5    Jia, D.6
  • 27
    • 0029682322 scopus 로고    scopus 로고
    • Site-directed mutagenesis in vitro by megaprimer PCR
    • Barik S. Site-directed mutagenesis in vitro by megaprimer PCR. Methods Mol Biol 1996;57:203-15.
    • (1996) Methods Mol Biol , vol.57 , pp. 203-215
    • Barik, S.1
  • 28
    • 23244455106 scopus 로고    scopus 로고
    • Absence of n-linked glycosylation does not affect plasma membrane localization of breast cancer resistance protein (bcrp/abcg2)
    • Mohrmann K, van Eijndhoven MA, Schinkel AH, Schellens JH. Absence of N-linked glycosylation does not affect plasma membrane localization of breast cancer resistance protein (BCRP/ABCG2). Cancer Chemother Pharmacol 2005;56:344-50.
    • (2005) Cancer Chemother Pharmacol , vol.56 , pp. 344-350
    • Mohrmann, K.1    Van Eijndhoven, M.A.2    Schinkel, A.H.3    Schellens, J.H.4
  • 29
    • 80054920730 scopus 로고    scopus 로고
    • Possibilities to increase the effectiveness of doxorubicin in cancer cells killing
    • Hanusova V, Bousova I, Skalova L. Possibilities to increase the effectiveness of doxorubicin in cancer cells killing. Drug Metab Rev 2011;43:540-57.
    • (2011) Drug Metab Rev , vol.43 , pp. 540-557
    • Hanusova, V.1    Bousova, I.2    Skalova, L.3
  • 30
    • 40749150740 scopus 로고    scopus 로고
    • Cd133+ hcc cancer stem cells confer chemoresistance by preferential expression of the akt/pkb survival pathway
    • Ma S, Lee TK, Zheng BJ, Chan KW, Guan XY. CD133+ HCC cancer stem cells confer chemoresistance by preferential expression of the Akt/PKB survival pathway. Oncogene 2008;27:1749-58.
    • (2008) Oncogene , vol.27 , pp. 1749-1758
    • Ma, S.1    Lee, T.K.2    Zheng, B.J.3    Chan, K.W.4    Guan, X.Y.5
  • 31
    • 0037308133 scopus 로고    scopus 로고
    • Systematic review of randomized trials for unresectable hepatocellular carcinoma: Chemoembolization improves survival
    • Llovet JM, Bruix J. Systematic review of randomized trials for unresectable hepatocellular carcinoma: Chemoembolization improves survival. Hepatology 2003;37:429-42.
    • (2003) Hepatology , vol.37 , pp. 429-442
    • Llovet, J.M.1    Bruix, J.2
  • 32
    • 78049252349 scopus 로고    scopus 로고
    • Simultaneous color-coded imaging to distinguish cancer "stem-like" and non-stem cells in the same tumor
    • Suetsugu A, Osawa Y, Nagaki M, Moriwaki H, Saji S, Bouvet M, et al. Simultaneous color-coded imaging to distinguish cancer "stem-like" and non-stem cells in the same tumor. J Cell Biochem 2010;111:1035-41
    • (2010) J Cell Biochem , vol.111 , pp. 1035-1041
    • Suetsugu, A.1    Osawa, Y.2    Nagaki, M.3    Moriwaki, H.4    Saji, S.5    Bouvet, M.6
  • 33
    • 67349279892 scopus 로고    scopus 로고
    • Activation of er stress and inhibition of egfr n-glycosylation by tunicamycin enhances susceptibility of human non-small cell lung cancer cells to erlotinib
    • Ling YH, Li T, Perez-Soler R, Haigentz MJ. Activation of ER stress and inhibition of EGFR N-glycosylation by tunicamycin enhances susceptibility of human non-small cell lung cancer cells to erlotinib. Cancer Chemother Pharmacol 2009;64:539-48.
    • (2009) Cancer Chemother Pharmacol , vol.64 , pp. 539-548
    • Ling, Y.H.1    Li, T.2    Perez-Soler, R.3    Haigentz, M.J.4
  • 34
    • 78149306403 scopus 로고    scopus 로고
    • Prolonged drug selection of breast cancer cells and enrichment of cancer stem cell characteristics
    • Calcagno AM, Salcido CD, Gillet JP, Wu CP, Fostel JM, Mumau MD, et al. Prolonged drug selection of breast cancer cells and enrichment of cancer stem cell characteristics. J Natl Cancer Inst 2010;102:1637-52.
    • (2010) J Natl Cancer Inst , vol.102 , pp. 1637-1652
    • Calcagno, A.M.1    Salcido, C.D.2    Gillet, J.P.3    Wu, C.P.4    Fostel, J.M.5    Mumau, M.D.6
  • 35
    • 84871965129 scopus 로고    scopus 로고
    • Molecular imaging reveals a role for AKT in resistance to cisplatin for ovarian endometrioid adenocarcinoma
    • Wang H, Galban S,WuR, Bowman B, Witte A, Vetter K, et al. Molecular imaging reveals a role for AKT in resistance to cisplatin for ovarian endometrioid adenocarcinoma. Clin Cancer Res 2013;19:158-69.
    • (2013) Clin Cancer Res , vol.19 , pp. 158-169
    • Wang, H.1    Galban, S.2    Wu, R.3    Bowman, B.4    Witte, A.5    Vetter, K.6
  • 36
    • 84864220149 scopus 로고    scopus 로고
    • Low molecular weight heparin ablates lung cancer cisplatin-resistance by inducing proteasome-mediatedABCG2protein degradation
    • Niu Q, Wang W, Li Y, Ruden DM, Wang F, Li Y, et al. Low molecular weight heparin ablates lung cancer cisplatin-resistance by inducing proteasome-mediatedABCG2protein degradation. PLoS One 2012;7: e41035
    • (2012) PLoS One , vol.7
    • Niu, Q.1    Wang, W.2    Li, Y.3    Ruden, D.M.4    Wang, F.5    Li, Y.6
  • 37
    • 84878258852 scopus 로고    scopus 로고
    • Effect of tunicamycin combined with cisplatin on proliferation and apoptosis of human nasopharyngeal carcinoma cells in vitro
    • Song L, Ma L, Zhang X, Jiang Z, Liu H, Jiang C. Effect of tunicamycin combined with cisplatin on proliferation and apoptosis of human nasopharyngeal carcinoma cells in vitro. Nan Fang Yi Ke Da Xue Xue Bao 2012;32:766-71.
    • (2012) Nan Fang Yi Ke Da Xue Xue Bao , vol.32 , pp. 766-771
    • Song, L.1    Ma, L.2    Zhang, X.3    Jiang, Z.4    Liu, H.5    Jiang, C.6
  • 38
    • 67650999377 scopus 로고    scopus 로고
    • Overexpression of DPAGT1 leads to aberrant N-glycosylation of E-cadherin and cellular discohesion in oral cancer
    • Nita-Lazar M, Noonan V, Rebustini I, Walker J, Menko AS, Kukuruzinska MA. Overexpression of DPAGT1 leads to aberrant N-glycosylation of E-cadherin and cellular discohesion in oral cancer. Cancer Res 2009;69:5673-80.
    • (2009) Cancer Res , vol.69 , pp. 5673-5680
    • Nita-Lazar, M.1    Noonan, V.2    Rebustini, I.3    Walker, J.4    Menko, A.S.5    Kukuruzinska, M.A.6
  • 39
    • 84861647963 scopus 로고    scopus 로고
    • Aberrant amplification of the crosstalk between canonical Wnt signaling and N-glycosylation gene DPAGT1 promotes oral cancer
    • Jamal B, Sengupta PK, Gao ZN, Nita-Lazar M, Amin B, Jalisi S, et al. Aberrant amplification of the crosstalk between canonical Wnt signaling and N-glycosylation gene DPAGT1 promotes oral cancer. Oral Oncol 2012;48:523-9.
    • (2012) Oral Oncol , vol.48 , pp. 523-529
    • Jamal, B.1    Sengupta, P.K.2    Gao, Z.N.3    Nita-Lazar, M.4    Amin, B.5    Jalisi, S.6
  • 40
    • 79958146175 scopus 로고    scopus 로고
    • Role of Wnt/beta-catenin signaling in liver metabolism and cancer
    • Monga SP. Role of Wnt/beta-catenin signaling in liver metabolism and cancer. Int J Biochem Cell Biol 2011;43:1021-9.
    • (2011) Int J Biochem Cell Biol , vol.43 , pp. 1021-1029
    • Monga, S.P.1
  • 41
    • 33846212284 scopus 로고    scopus 로고
    • Sorafenib blocks the RAF/MEK/ERK pathway, inhibits tumor angiogenesis, and induces tumor cell apoptosis in hepatocellular carcinoma model PLC/ PRF/5
    • Liu L, Cao Y, Chen C, Zhang X, McNabola A, Wilkie D, et al. Sorafenib blocks the RAF/MEK/ERK pathway, inhibits tumor angiogenesis, and induces tumor cell apoptosis in hepatocellular carcinoma model PLC/ PRF/5. Cancer Res 2006;66:11851-8.
    • (2006) Cancer Res , vol.66 , pp. 11851-11858
    • Liu, L.1    Cao, Y.2    Chen, C.3    Zhang, X.4    McNabola, A.5    Wilkie, D.6
  • 43
    • 84869758057 scopus 로고    scopus 로고
    • Sorafenib down-regulates expression of HTATIP2 to promote invasiveness and metastasis of orthotopic hepatocellular carcinoma tumors in mice
    • Zhang W, Sun HC, Wang WQ, Zhang QB, Zhuang PY, Xiong YQ, et al. Sorafenib down-regulates expression of HTATIP2 to promote invasiveness and metastasis of orthotopic hepatocellular carcinoma tumors in mice. Gastroenterology 2012;143:1641-9.
    • (2012) Gastroenterology , vol.143 , pp. 1641-1649
    • Zhang, W.1    Sun, H.C.2    Wang, W.Q.3    Zhang, Q.B.4    Zhuang, P.Y.5    Xiong, Y.Q.6
  • 44
    • 0020569657 scopus 로고
    • Biochemical effects and therapeutic potential of tunicamycin in murine L1210 leukemia
    • Morin MJ, Bernacki RJ. Biochemical effects and therapeutic potential of tunicamycin in murine L1210 leukemia. Cancer Res 1983;43: 1669-74.
    • (1983) Cancer Res , vol.43 , pp. 1669-1674
    • Morin, M.J.1    Bernacki, R.J.2
  • 45
    • 45549099309 scopus 로고    scopus 로고
    • Inhibition of N-linked glycosylation disrupts receptor tyrosine kinase signaling in tumor cells
    • Contessa JN, Bhojani MS, Freeze HH, Rehemtulla A, Lawrence TS. Inhibition of N-linked glycosylation disrupts receptor tyrosine kinase signaling in tumor cells. Cancer Res 2008;68:3803-9.
    • (2008) Cancer Res , vol.68 , pp. 3803-3809
    • Contessa, J.N.1    Bhojani, M.S.2    Freeze, H.H.3    Rehemtulla, A.4    Lawrence, T.S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.