Increased antitumor efficacy by the combined administration of swainsonine and cisplatin in vivo

Phytomedicine

Volumn 18, Issue 12, 2011, Pages 1096-1101

  Santos, Felipe M ^a   Latorre, Andreia O ^a   Hueza, Isis M ^b   Sanches, Daniel S ^a   Lippi, Luciana L ^a   Gardner, Dale R ^c   Spinosa, Helenice S ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^c Poisonous Plant Research Laboratory   (United States)

Author keywords

Mannosidase inhibitor; Astragalus lentiginosus; Cancer chemotherapy; Cell cycle; Cis diamminedichloroplatinum (II); Golgi mannosidase II; Swainsonine

Indexed keywords

ALPHA MANNOSIDASE; CISPLATIN; GLYCAN; SWAINSONINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL CYCLE G1 PHASE; CONTROLLED STUDY; DRUG EFFICACY; DRUG POTENTIATION; DRUG STRUCTURE; EHRLICH ASCITES TUMOR; ENZYME ACTIVITY; MALE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; SURVIVAL; TREATMENT DURATION;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; BLOOD CELL COUNT; CARCINOMA, EHRLICH TUMOR; CELL CYCLE; CISPLATIN; DRUG SYNERGISM; DRUG THERAPY, COMBINATION; MALE; MICE; MICE, INBRED C57BL; SURVIVAL ANALYSIS; SWAINSONINE; WEIGHT GAIN;

ASTRAGALUS LENTIGINOSUS; MUS;

EID: 80052505362     PISSN: 09447113     EISSN: 1618095X     Source Type: Journal    
DOI: 10.1016/j.phymed.2011.06.005     Document Type: Article

References (22)

1. V. Draheim, A. Reichel, W. Weitschies, and U. Moenning N-glycosylation of ABC transporters is associated with functional activity in sandwich-cultured rat hepatocytes Eur. J. Pharm. Sci. 41 2010 201 209
2. M.M. Fuster, and J.D. Esko The sweet and sour of cancer: glycans as novel therapeutic targets Nat. Rev. Cancer 5 2005 526 542 (Pubitemid 40942829)
3. C. Galustian, S. Foulds, J.F. Dye, and P.J. Guillou Swainsonine, a glycosylation inhibitor, enhances both lymphocyte efficacy and tumour susceptibility in LAK and NK cytotoxicity Immunopharmacology 27 1994 165 172 (Pubitemid 24073727)
4. D.R. Gardner, S.T. Lee, R.J. Molyneux, and J.A. Edgar Preparative isolation of swainsonine from locoweed: extraction and purification procedures Phytochem. Anal. 14 2003 259 266 (Pubitemid 36926572)
5. S. Gerber-Lemaire, and L. Juillerat-Jeanneret Studies toward new anti-cancer strategies based on α-mannosidase inhibition Chimia 64 2010 634 639
6. P.E. Goss, J. Baptiste, B. Fernandes, M. Baker, and J.W. Dennis A phase I study of swainsonine in patients with advanced malignancies Cancer Res. 54 1994 1450 1457 (Pubitemid 24106405)
7. P.E. Goss, C.L. Reid, D. Bailey, and J.W. Dennis Phase IB clinical trial of the oligosaccharide processing inhibitor swainsonine in patients with advanced malignancies Clin. Cancer Res. 3 1997 1077 1086 (Pubitemid 27319753)
8. M.M. Gottesman, T. Fojo, and S.E. Bates Multidrug resistance in cancer: role of ATP-dependent transporters Nat. Rev. Cancer 2 2002 48 58 (Pubitemid 37328807)
9. J. Hamaguchi, H. Nakagawa, M. Takahashi, T. Kudo, N. Kamiyama, B. Sun, T. Oshima, Y. Sato, K. Deguchi, S. Todo, and S.I. Nishimura Swainsonine reduces 5-fluorouracil tolerance in the multistage resistance of colorectal cancer cell lines Mol. Cancer 6 2007 1 9
10. M.E. Janik, A. Lityńska, and P. Vereecken Cell migration - the role of integrin glycosylation Biochim. Biophys. Acta: Gen. Subjects 1800 2010 545 555
11. G. Klein Comparative studies of mouse tumors with respect to their capacity for growth as "ascites tumors" and their average nucleic acid content per cell Exp. Cell Res. 2 1951 518 573
12. R.J. Molyneux, and L.F. James Loco intoxication: indolizidine alkaloids of spotted locoweed (Astragalus lentiginosus) Science 216 1982 190 191 (Pubitemid 12089842)
13. D.O. Morgan The DNA damage response E. Lawrence, The Cell Cycle. Principles of Control 2007 New Science Press Ltd. London 228 244
14. O. Oredipe, P. Furbert-Harris, W. Green, S. White, K. Olden, I. Laniyan, D. Parish-Gause, T. Vaughn, W. Griffin, and R. Sridhar Swainsonine stimulates bone marrow cell proliferation and differentiation in different strains of inbred mice Pharmacol. Res. 47 2003 69 74 (Pubitemid 36259624)
15. N. Pabla, and Z. Dong Cisplatin nephrotoxicity: mechanisms and renoprotective strategies Kidney Int. 73 2008 994 1007 (Pubitemid 351543900)
16. P.E. Shaheen, W. Stadler, P. Elson, J. Knox, E. Winquist, and R.M. Bukowski Phase II study of the efficacy and safety of oral GD0039 in patients with locally advanced or metastatic renal cell carcinoma Invest. New Drugs 23 2005 577 581 (Pubitemid 43162478)
17. Z.H. Siddik Cisplatin: mode of cytotoxic action and molecular basis of resistance Oncogene 22 2003 7265 7279 (Pubitemid 37487159)
18. J.Y. Sun, H. Yang, S. Miao, J.P. Li, S.W. Wang, M.Z. Zhu, Y.H. Xie, J.B. Wang, Z. Liu, and Q. Yang Suppressive effects of swainsonine on C6 glioma cell in vitro and in vivo Phytomedicine 16 2009 1070 1074
19. J.Y. Sun, M.Z. Zhu, S.W. Wang, S. Miao, Y.H. Xie, and J.B. Wang Inhibition of the growth of human gastric carcinoma in vivo and in vitro by swainsonine Phytomedicine 14 2007 353 359 (Pubitemid 46654787)
20. S. Veneroni, N. Zaffaroni, M.G. Daidone, E. Benini, R. Villa, and R. Silvestrini Expression of P-glycoprotein and in vitro or in vivo resistance to doxorubicin and cisplatin in breast and ovarian cancers Eur. J. Cancer Part A: Gen. Top. 30 1994 1002 1007 (Pubitemid 24256252)
21. T.M. Wrodnigg, A.J. Steiner, and B.J. Ueberbacher Natural and synthetic iminosugars as carbohydrate processing enzyme inhibitors for cancer therapy Anti-Cancer Agents Med. Chem. 8 2008 77 85 (Pubitemid 351445062)
22. Y.Y. Zhao, M. Takahashi, J.G. Gu, E. Miyoshi, A. Matsumoto, S. Kitazume, and N. Taniguchi Functional roles of N-glycans in cell signaling and cell adhesion in cancer Cancer Sci. 99 2008 1304 1310 (Pubitemid 351761717)