Modulation of HERG K channels by chronic exposure to activators and inhibitors of PKA and PKC: Actions independent of PKA and PKC phosphorylation

Cellular Physiology and Biochemistry

Volumn 32, Issue 6, 2013, Pages 1830-1844

  Shu, Liliang ^a   Zhang, Wanzhe ^b   Su, Gang ^a   Zhang, Jingchao ^a   Liu, Chao ^a   Xu, Jing ^a  

^a THE FIRST AFFILIATED HOSPITAL OF ZHENGZHOU UNIVERSITY   (China)

^b ZHENGZHOU UNIVERSITY   (China)

Author keywords

HERG; MnTBAP; Protein kinase A; Protein kinase C; Reactive oxygen species (ROS); Vitamin E

Indexed keywords

ALPHA TOCOPHEROL; ANTIOXIDANT; BISINDOLYLMALEIMIDE; CYCLIC AMP DEPENDENT PROTEIN KINASE; FORSKOLIN; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; PHOSPHATE P 32; POTASSIUM CHANNEL HERG; PROTEIN KINASE C; PROTEIN KINASE C ACTIVATOR; REACTIVE OXYGEN METABOLITE; CYCLIC AMP DEPENDENT PROTEIN KINASE ACTIVATOR; CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; ENZYME ACTIVATOR; PROTEIN KINASE C INHIBITOR; UNCLASSIFIED DRUG;

ANTIOXIDANT ACTIVITY; ARTICLE; CELL STRAIN HEK293; CONTROLLED STUDY; ENZYME ACTIVITY; LONG TERM EXPOSURE; MITOCHONDRIAL MEMBRANE POTENTIAL; MODULATION; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; STEADY STATE; WHOLE CELL PATCH CLAMP; ASSAY; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; INCUBATION TIME; PROTEIN EXPRESSION; PROTEIN FUNCTION;

COLFORSIN; CYCLIC AMP-DEPENDENT PROTEIN KINASES; ETHER-A-GO-GO POTASSIUM CHANNELS; HEK293 CELLS; HUMANS; INDOLES; ISOQUINOLINES; MALEIMIDES; MEMBRANE POTENTIAL, MITOCHONDRIAL; METALLOPORPHYRINS; PATCH-CLAMP TECHNIQUES; PHOSPHORYLATION; PROTEIN KINASE C; REACTIVE OXYGEN SPECIES; SULFONAMIDES; TETRADECANOYLPHORBOL ACETATE;

EID: 84890480714     PISSN: 10158987     EISSN: 14219778     Source Type: Journal    
DOI: 10.1159/000356616     Document Type: Article

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