Control of oxygen free radical formation from mitochondrial complex I: Roles for protein kinase A and pyruvate dehydrogenase kinase

Free Radical Biology and Medicine

Volumn 32, Issue 5, 2002, Pages 421-430

  Raha, Sandeep ^a   Myint, A Tomoko ^a   Johnstone, Leslie ^a   Robinson, Brian H ^a,b  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

Coelenterazine; Complex I; Free radicals; Mitochondria; Protein kinase A; Pyruvate dehydrogenase kinase; Reactive oxygen species

Indexed keywords

ADENOSINE TRIPHOSPHATE; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; CYCLIC AMP DERIVATIVE; OXYGEN RADICAL; PROTEIN; PROTEIN NDUFA1; PROTEIN NDUFS4; PROTEIN SUBUNIT; PYRUVATE DEHYDROGENASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); SUPEROXIDE; UNCLASSIFIED DRUG; (PYRUVATE DEHYDROGENASE (LIPOAMIDE))KINASE; COELENTERAZINE; CYCLIC AMP; IMIDAZOLE DERIVATIVE; LUCIFERIN; MEMBRANE PROTEIN; NDUFA1 PROTEIN, HUMAN; NDUFA1 PROTEIN, MAMMALIAN; NDUFS4 PROTEIN, HUMAN; NICOTINAMIDE ADENINE DINUCLEOTIDE; OXIDOREDUCTASE; PROTEIN KINASE; PROTEIN KINASE INHIBITOR; PYRAZINE DERIVATIVE; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ELECTRON TRANSPORT; ENZYME ACTIVITY; ENZYME REGULATION; HEART MITOCHONDRION; INCUBATION TIME; MITOCHONDRIAL MEMBRANE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; ANIMAL; COMPARATIVE STUDY; DRUG ANTAGONISM; DRUG EFFECT; ENZYME ACTIVATION; ENZYMOLOGY; HUMAN; METABOLISM; OXYGEN CONSUMPTION; PHOSPHORYLATION; WESTERN BLOTTING; WISTAR RAT;

ADENOSINE TRIPHOSPHATE; ANIMAL; BLOTTING, WESTERN; COMPARATIVE STUDY; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; ENZYME ACTIVATION; HUMAN; LUCIFERINS; MEMBRANE PROTEINS; MITOCHONDRIA, HEART; NAD; NADH DEHYDROGENASE; NADH, NADPH OXIDOREDUCTASES; OXYGEN CONSUMPTION; PHOSPHORYLATION; PROTEIN KINASES; PYRAZINES; RATS; RATS, WISTAR; REACTIVE OXYGEN SPECIES; SUPEROXIDES; SUPPORT, NON-U.S. GOV'T; ANIMALS; ELECTRON TRANSPORT COMPLEX I; FIREFLY LUCIFERIN; HUMANS; IMIDAZOLES; PROTEIN KINASE INHIBITORS;

EID: 0036489190     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-5849(01)00816-4     Document Type: Article

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