-
1
-
-
0035064760
-
Adrenal and sex steroid receptor evolution: Environmental implications
-
11241163 1:CAS:528:DC%2BD3MXis1Kls78%3D 10.1677/jme.0.0260119
-
Baker ME (2001) Adrenal and sex steroid receptor evolution: environmental implications. J Mol Endocrinol 26:119-125
-
(2001)
J Mol Endocrinol
, vol.26
, pp. 119-125
-
-
Baker, M.E.1
-
2
-
-
80053380047
-
Long-term use of low-dose spironolactone in spontaneously hypertensive rats: Effects on left ventricular hypertrophy and stiffness
-
22001985 1:CAS:528:DC%2BC38XitlOgtr8%3D
-
Baldo MP, Forechi L, Morra EA, Zaniqueli D, Machado RC, Lunz W, Rodrigues SL, Mill JG (2011) Long-term use of low-dose spironolactone in spontaneously hypertensive rats: effects on left ventricular hypertrophy and stiffness. Pharmacol Rep 63(4):975-982
-
(2011)
Pharmacol Rep
, vol.63
, Issue.4
, pp. 975-982
-
-
Baldo, M.P.1
Forechi, L.2
Morra, E.A.3
Zaniqueli, D.4
Machado, R.C.5
Lunz, W.6
Rodrigues, S.L.7
Mill, J.G.8
-
4
-
-
35348887226
-
Prehypertensive renin-angiotensin-aldosterone system blockade in spontaneously hypertensive rats ameliorates the loss of long-term vascular function
-
18037779 1:CAS:528:DC%2BD2sXhsVyjtrvN 10.1291/hypres.30.853
-
Baumann M, Megens R, Bartholome R, Dolff S, van Zandvoort MA, Smits JF, Struijker-Boudier HA, De Mey JG (2007) Prehypertensive renin-angiotensin- aldosterone system blockade in spontaneously hypertensive rats ameliorates the loss of long-term vascular function. Hypertens Res 30(9):853-861
-
(2007)
Hypertens Res
, vol.30
, Issue.9
, pp. 853-861
-
-
Baumann, M.1
Megens, R.2
Bartholome, R.3
Dolff, S.4
Van Zandvoort, M.A.5
Smits, J.F.6
Struijker-Boudier, H.A.7
De Mey, J.G.8
-
5
-
-
65349128571
-
Disruption of the Ang II type 1 receptor promotes longevity in mice
-
19197138 1:CAS:528:DC%2BD1MXivF2kt7k%3D 10.1172/JCI36703
-
Benigni A, Corna D, Zoja C, Sonzogni A, Latini R, Salio M, Conti S, Rottoli D, Longaretti L, Cassis P et al (2009) Disruption of the Ang II type 1 receptor promotes longevity in mice. J Clin Invest 119(3):524-530
-
(2009)
J Clin Invest
, vol.119
, Issue.3
, pp. 524-530
-
-
Benigni, A.1
Corna, D.2
Zoja, C.3
Sonzogni, A.4
Latini, R.5
Salio, M.6
Conti, S.7
Rottoli, D.8
Longaretti, L.9
Cassis, P.10
-
6
-
-
13144251124
-
Mineralocorticoid receptor knockout mice: Pathophysiology of Na + metabolism
-
9689096 1:CAS:528:DyaK1cXltlClsrg%3D 10.1073/pnas.95.16.9424
-
Berger S, Bleich M, Schmid W, Cole TJ, Peters J, Watanabe H, Kriz W, Warth R, Greger R, Schutz G (1998) Mineralocorticoid receptor knockout mice: pathophysiology of Na + metabolism. Proc Natl Acad Sci U S A 95(16):9424-9429
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, Issue.16
, pp. 9424-9429
-
-
Berger, S.1
Bleich, M.2
Schmid, W.3
Cole, T.J.4
Peters, J.5
Watanabe, H.6
Kriz, W.7
Warth, R.8
Greger, R.9
Schutz, G.10
-
7
-
-
0034079744
-
Mineralocorticoid receptor knockout mice: Lessons on Na + metabolism
-
10760057 1:CAS:528:DC%2BD3cXjtVOrsbw%3D 10.1046/j.1523-1755.2000.00965.x
-
Berger S, Bleich M, Schmid W, Greger R, Schutz G (2000) Mineralocorticoid receptor knockout mice: lessons on Na + metabolism. Kidney Int 57(4):1295-1298
-
(2000)
Kidney Int
, vol.57
, Issue.4
, pp. 1295-1298
-
-
Berger, S.1
Bleich, M.2
Schmid, W.3
Greger, R.4
Schutz, G.5
-
8
-
-
59849099633
-
Arterial stiffness, intima-media thickness and carotid artery fibrosis in patients with primary aldosteronism
-
19008719 1:CAS:528:DC%2BD1cXhtlKrtrjE 10.1097/HJH.0b013e32831286fd
-
Bernini G, Galetta F, Franzoni F, Bardini M, Taurino C, Bernardini M, Ghiadoni L, Bernini M, Santoro G, Salvetti A (2008) Arterial stiffness, intima-media thickness and carotid artery fibrosis in patients with primary aldosteronism. J Hypertens 26(12):2399-2405
-
(2008)
J Hypertens
, vol.26
, Issue.12
, pp. 2399-2405
-
-
Bernini, G.1
Galetta, F.2
Franzoni, F.3
Bardini, M.4
Taurino, C.5
Bernardini, M.6
Ghiadoni, L.7
Bernini, M.8
Santoro, G.9
Salvetti, A.10
-
9
-
-
2342477841
-
Regulation of epithelial ion transport by aldosterone through changes in gene expression
-
15134817 1:CAS:528:DC%2BD2cXjvVequ7w%3D 10.1016/j.mce.2003.10.020
-
Bhargava A, Wang J, Pearce D (2004) Regulation of epithelial ion transport by aldosterone through changes in gene expression. Mol Cell Endocrinol 217(1-2):189-196
-
(2004)
Mol Cell Endocrinol
, vol.217
, Issue.1-2
, pp. 189-196
-
-
Bhargava, A.1
Wang, J.2
Pearce, D.3
-
10
-
-
73749085801
-
Angiotensin receptors as determinants of life span
-
19763608 1:CAS:528:DC%2BC3cXisVSktg%3D%3D 10.1007/s00424-009-0725-4
-
Cassis P, Conti S, Remuzzi G, Benigni A (2010) Angiotensin receptors as determinants of life span. Pflugers Arch 459(2):325-332
-
(2010)
Pflugers Arch
, vol.459
, Issue.2
, pp. 325-332
-
-
Cassis, P.1
Conti, S.2
Remuzzi, G.3
Benigni, A.4
-
11
-
-
84860221324
-
Altered functioning of both renal dopamine D1 and angiotensin II type 1 receptors causes hypertension in old rats
-
22411927 1:CAS:528:DC%2BC38Xls12ks7w%3D 10.1161/HYPERTENSIONAHA.112. 192302
-
Chugh G, Lokhandwala MF, Asghar M (2012) Altered functioning of both renal dopamine D1 and angiotensin II type 1 receptors causes hypertension in old rats. Hypertension 59(5):1029-1036
-
(2012)
Hypertension
, vol.59
, Issue.5
, pp. 1029-1036
-
-
Chugh, G.1
Lokhandwala, M.F.2
Asghar, M.3
-
12
-
-
12744253849
-
Eplerenone: A review of its use in essential hypertension
-
15631538 1:CAS:528:DC%2BD2MXhsFekurk%3D 10.2165/00129784-200505010-00007
-
Croom KF, Perry CM (2005) Eplerenone: a review of its use in essential hypertension. Am J Cardiovasc Drugs 5(1):51-69
-
(2005)
Am J Cardiovasc Drugs
, vol.5
, Issue.1
, pp. 51-69
-
-
Croom, K.F.1
Perry, C.M.2
-
13
-
-
6944244066
-
Distinct endothelial phenotypes evoked by arterial waveforms derived from atherosclerosis-susceptible and -resistant regions of human vasculature
-
15466704 1:CAS:528:DC%2BD2cXovVyisrg%3D 10.1073/pnas.0406073101
-
Dai G, Kaazempur-Mofrad MR, Natarajan S, Zhang Y, Vaughn S, Blackman BR, Kamm RD, Garcia-Cardena G, Gimbrone MA Jr (2004) Distinct endothelial phenotypes evoked by arterial waveforms derived from atherosclerosis-susceptible and -resistant regions of human vasculature. Proc Natl Acad Sci U S A 101(41):14871-14876
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, Issue.41
, pp. 14871-14876
-
-
Dai, G.1
Kaazempur-Mofrad, M.R.2
Natarajan, S.3
Zhang, Y.4
Vaughn, S.5
Blackman, B.R.6
Kamm, R.D.7
Garcia-Cardena, G.8
Gimbrone, Jr.M.A.9
-
14
-
-
78650850729
-
11β-hydroxysteroid dehydrogenase type 2 deficiency accelerates atherogenesis and causes proinflammatory changes in the endothelium in apoe-/- mice
-
21106873 1:CAS:528:DC%2BC3MXitVCisL8%3D 10.1210/en.2010-0925
-
Deuchar GA, McLean D, Hadoke PW, Brownstein DG, Webb DJ, Mullins JJ, Chapman K, Seckl JR, Kotelevtsev YV (2011) 11β-hydroxysteroid dehydrogenase type 2 deficiency accelerates atherogenesis and causes proinflammatory changes in the endothelium in apoe-/- mice. Endocrinology 152(1):236-246
-
(2011)
Endocrinology
, vol.152
, Issue.1
, pp. 236-246
-
-
Deuchar, G.A.1
McLean, D.2
Hadoke, P.W.3
Brownstein, D.G.4
Webb, D.J.5
Mullins, J.J.6
Chapman, K.7
Seckl, J.R.8
Kotelevtsev, Y.V.9
-
15
-
-
60249096205
-
Aldosterone and mineralocorticoid receptors: Clinical studies and basic biology
-
19026715 1:CAS:528:DC%2BD1MXit1Ogs74%3D 10.1016/j.mce.2008.10.029
-
Funder JW, Mihailidou AS (2009) Aldosterone and mineralocorticoid receptors: clinical studies and basic biology. Mol Cell Endocrinol 301(1-2):2-6
-
(2009)
Mol Cell Endocrinol
, vol.301
, Issue.1-2
, pp. 2-6
-
-
Funder, J.W.1
Mihailidou, A.S.2
-
16
-
-
0024442132
-
Vascular type i aldosterone binding sites are physiological mineralocorticoid receptors
-
2551643 1:CAS:528:DyaL1MXmtV2gsb8%3D 10.1210/endo-125-4-2224
-
Funder JW, Pearce PT, Smith R, Campbell J (1989) Vascular type I aldosterone binding sites are physiological mineralocorticoid receptors. Endocrinology 125(4):2224-2226
-
(1989)
Endocrinology
, vol.125
, Issue.4
, pp. 2224-2226
-
-
Funder, J.W.1
Pearce, P.T.2
Smith, R.3
Campbell, J.4
-
17
-
-
84862874414
-
Smooth muscle cell phenotypic switching in atherosclerosis
-
22406749 1:CAS:528:DC%2BC38XhtVSht7%2FJ 10.1093/cvr/cvs115
-
Gomez D, Owens GK (2012) Smooth muscle cell phenotypic switching in atherosclerosis. Cardiovasc Res 95(2):156-164
-
(2012)
Cardiovasc Res
, vol.95
, Issue.2
, pp. 156-164
-
-
Gomez, D.1
Owens, G.K.2
-
18
-
-
69949125930
-
Role of angiotensin II type 1 receptor antagonists in the treatment of hypertension in patients aged >65 years
-
19728749 1:CAS:528:DC%2BD1MXhsVCkt77L 10.2165/11316790-000000000-00000
-
Gradman AH (2009) Role of angiotensin II type 1 receptor antagonists in the treatment of hypertension in patients aged >65 years. Drugs Aging 26(9):751-767
-
(2009)
Drugs Aging
, vol.26
, Issue.9
, pp. 751-767
-
-
Gradman, A.H.1
-
20
-
-
34447562739
-
Aldosterone-induced EGFR expression: Interaction between the human mineralocorticoid receptor and the human EGFR promoter
-
17311890 1:CAS:528:DC%2BD2sXmvF2mtb8%3D 10.1152/ajpendo.00708.2006
-
Grossmann C, Krug AW, Freudinger R, Mildenberger S, Voelker K, Gekle M (2007) Aldosterone-induced EGFR expression: interaction between the human mineralocorticoid receptor and the human EGFR promoter. Am J Physiol Endocrinol Metab 292(6):E1790-E1800
-
(2007)
Am J Physiol Endocrinol Metab
, vol.292
, Issue.6
-
-
Grossmann, C.1
Krug, A.W.2
Freudinger, R.3
Mildenberger, S.4
Voelker, K.5
Gekle, M.6
-
21
-
-
79951669207
-
The immune system in atherosclerosis
-
21321594 1:CAS:528:DC%2BC3MXhvFWks7k%3D 10.1038/ni.2001
-
Hansson GK, Hermansson A (2011) The immune system in atherosclerosis. Nat Immunol 12(3):204-212
-
(2011)
Nat Immunol
, vol.12
, Issue.3
, pp. 204-212
-
-
Hansson, G.K.1
Hermansson, A.2
-
22
-
-
65549143758
-
Human IL-8 regulates smooth muscle cell VCAM-1 expression in response to endothelial cells exposed to atheroprone flow
-
19229069 1:CAS:528:DC%2BD1MXktF2qtbs%3D 10.1161/ATVBAHA.109.184382
-
Hastings NE, Feaver RE, Lee MY, Wamhoff BR, Blackman BR (2009) Human IL-8 regulates smooth muscle cell VCAM-1 expression in response to endothelial cells exposed to atheroprone flow. Arterioscler Thromb Vasc Biol 29(5):725-731
-
(2009)
Arterioscler Thromb Vasc Biol
, vol.29
, Issue.5
, pp. 725-731
-
-
Hastings, N.E.1
Feaver, R.E.2
Lee, M.Y.3
Wamhoff, B.R.4
Blackman, B.R.5
-
23
-
-
84883294542
-
Aldosterone, atherosclerosis and vascular events in patients with stable coronary artery disease
-
10.1016/j.ijcard.2012.05.034 22727970
-
Hillaert M, Lentjes EG, Kemperman H, van der Graaf Y, Nathoe HM, Beygui F, Montalescot G, Doevendans PA, Wassink AM, Van Belle E et al (2012) Aldosterone, atherosclerosis and vascular events in patients with stable coronary artery disease. Int J Cardiol. doi: 10.1016/j.ijcard.2012.05.034
-
(2012)
Int J Cardiol
-
-
Hillaert, M.1
Lentjes, E.G.2
Kemperman, H.3
Van Der Graaf, Y.4
Nathoe, H.M.5
Beygui, F.6
Montalescot, G.7
Doevendans, P.A.8
Wassink, A.M.9
Van Belle, E.10
-
24
-
-
80053641993
-
Measuring and targeting aldosterone and renin in atherosclerosis - A review of clinical data
-
21982648 1:CAS:528:DC%2BC3MXht1OhsbfF 10.1016/j.ahj.2011.06.015
-
Hillaert MA, Lentjes EG, Beygui F, Kemperman H, Asselbergs FW, Nathoe HM, Agostoni P, Voskuil M, Ivanes F, Jude B et al (2011) Measuring and targeting aldosterone and renin in atherosclerosis - a review of clinical data. Am Heart J 162(4):585-596
-
(2011)
Am Heart J
, vol.162
, Issue.4
, pp. 585-596
-
-
Hillaert, M.A.1
Lentjes, E.G.2
Beygui, F.3
Kemperman, H.4
Asselbergs, F.W.5
Nathoe, H.M.6
Agostoni, P.7
Voskuil, M.8
Ivanes, F.9
Jude, B.10
-
25
-
-
84864541822
-
Initiation of angiogenesis in atherosclerosis: Smooth muscle cells as mediators of the angiogenic response to atheroma formation
-
22867696 1:CAS:528:DC%2BC38XhtFKnsLrJ 10.1016/j.tcm.2012.05.007
-
Ho-Tin-Noe B, Michel JB (2011) Initiation of angiogenesis in atherosclerosis: smooth muscle cells as mediators of the angiogenic response to atheroma formation. Trends Cardiovasc Med 21(7):183-187
-
(2011)
Trends Cardiovasc Med
, vol.21
, Issue.7
, pp. 183-187
-
-
Ho-Tin-Noe, B.1
Michel, J.B.2
-
26
-
-
12844256402
-
The biology of cyclic GMP-dependent protein kinases
-
15545263 1:CAS:528:DC%2BD2cXhtFGgu7zL
-
Hofmann F (2005) The biology of cyclic GMP-dependent protein kinases. J Biol Chem 280(1):1-4
-
(2005)
J Biol Chem
, vol.280
, Issue.1
, pp. 1-4
-
-
Hofmann, F.1
-
27
-
-
34250313556
-
Increased intima-media thickness of the common carotid artery in primary aldosteronism in comparison with essential hypertension
-
17563568 1:CAS:528:DC%2BD2sXmtlWntro%3D 10.1097/HJH.0b013e3281268532
-
Holaj R, Zelinka T, Wichterle D, Petrak O, Strauch B, Widimsky J Jr (2007) Increased intima-media thickness of the common carotid artery in primary aldosteronism in comparison with essential hypertension. J Hypertens 25(7):1451-1457
-
(2007)
J Hypertens
, vol.25
, Issue.7
, pp. 1451-1457
-
-
Holaj, R.1
Zelinka, T.2
Wichterle, D.3
Petrak, O.4
Strauch, B.5
Widimsky, Jr.J.6
-
28
-
-
70349653450
-
Blood pressure control in the elderly: Can you have too much of a good thing?
-
19737450 10.1007/s11906-009-0057-y
-
Hyman DJ, Taffet GE (2009) Blood pressure control in the elderly: can you have too much of a good thing? Curr Hypertens Rep 11(5):337-342
-
(2009)
Curr Hypertens Rep
, vol.11
, Issue.5
, pp. 337-342
-
-
Hyman, D.J.1
Taffet, G.E.2
-
29
-
-
84870197180
-
Contribution of endogenous glucocorticoids and their intravascular metabolism by 11beta-HSDs to postangioplasty neointimal proliferation in mice
-
23125311 1:CAS:528:DC%2BC38XhvVahtbjI 10.1210/en.2012-1481
-
Iqbal J, Macdonald LJ, Low L, Seckl JR, Yau CW, Walker BR, Hadoke PW (2012) Contribution of endogenous glucocorticoids and their intravascular metabolism by 11beta-HSDs to postangioplasty neointimal proliferation in mice. Endocrinology 153(12):5896-5905
-
(2012)
Endocrinology
, vol.153
, Issue.12
, pp. 5896-5905
-
-
Iqbal, J.1
Macdonald, L.J.2
Low, L.3
Seckl, J.R.4
Yau, C.W.5
Walker, B.R.6
Hadoke, P.W.7
-
30
-
-
84856143583
-
Aldosterone, mortality, and acute ischaemic events in coronary artery disease patients outside the setting of acute myocardial infarction or heart failure
-
21719456 1:CAS:528:DC%2BC38XhtVCnsrs%3D 10.1093/eurheartj/ehr176
-
Ivanes F, Susen S, Mouquet F, Pigny P, Cuilleret F, Sautiere K, Collet JP, Beygui F, Hennache B, Ennezat PV et al (2012) Aldosterone, mortality, and acute ischaemic events in coronary artery disease patients outside the setting of acute myocardial infarction or heart failure. Eur Heart J 33(2):191-202
-
(2012)
Eur Heart J
, vol.33
, Issue.2
, pp. 191-202
-
-
Ivanes, F.1
Susen, S.2
Mouquet, F.3
Pigny, P.4
Cuilleret, F.5
Sautiere, K.6
Collet, J.P.7
Beygui, F.8
Hennache, B.9
Ennezat, P.V.10
-
31
-
-
16444375794
-
Angiotensin II and aldosterone regulate gene transcription via functional mineralocortocoid receptors in human coronary artery smooth muscle cells
-
15718497 1:CAS:528:DC%2BD2MXis1elsL0%3D 10.1161/01.RES.0000159937.05502. d1
-
Jaffe IZ, Mendelsohn ME (2005) Angiotensin II and aldosterone regulate gene transcription via functional mineralocortocoid receptors in human coronary artery smooth muscle cells. Circ Res 96(6):643-650
-
(2005)
Circ Res
, vol.96
, Issue.6
, pp. 643-650
-
-
Jaffe, I.Z.1
Mendelsohn, M.E.2
-
32
-
-
78049438298
-
Placental growth factor mediates aldosterone-dependent vascular injury in mice
-
20921624 1:CAS:528:DC%2BC3cXhsVWgtbvN 10.1172/JCI40205
-
Jaffe IZ, Newfell BG, Aronovitz M, Mohammad NN, McGraw AP, Perreault RE, Carmeliet P, Ehsan A, Mendelsohn ME (2010) Placental growth factor mediates aldosterone-dependent vascular injury in mice. J Clin Invest 120(11):3891-3900
-
(2010)
J Clin Invest
, vol.120
, Issue.11
, pp. 3891-3900
-
-
Jaffe, I.Z.1
Newfell, B.G.2
Aronovitz, M.3
Mohammad, N.N.4
McGraw, A.P.5
Perreault, R.E.6
Carmeliet, P.7
Ehsan, A.8
Mendelsohn, M.E.9
-
33
-
-
34247209264
-
Mineralocorticoid receptor activation promotes vascular cell calcification
-
17234727 1:CAS:528:DC%2BD2sXislCku7o%3D 10.1161/01.ATV.0000258414.59393. 89
-
Jaffe IZ, Tintut Y, Newfell BG, Demer LL, Mendelsohn ME (2007) Mineralocorticoid receptor activation promotes vascular cell calcification. Arterioscler Thromb Vasc Biol 27(4):799-805
-
(2007)
Arterioscler Thromb Vasc Biol
, vol.27
, Issue.4
, pp. 799-805
-
-
Jaffe, I.Z.1
Tintut, Y.2
Newfell, B.G.3
Demer, L.L.4
Mendelsohn, M.E.5
-
34
-
-
33750904801
-
Vascular calcification: Pathobiological mechanisms and clinical implications
-
17095733 1:CAS:528:DC%2BD28XhtFKgurrN 10.1161/01.RES.0000249379.55535.21
-
Johnson RC, Leopold JA, Loscalzo J (2006) Vascular calcification: pathobiological mechanisms and clinical implications. Circ Res 99(10):1044-1059
-
(2006)
Circ Res
, vol.99
, Issue.10
, pp. 1044-1059
-
-
Johnson, R.C.1
Leopold, J.A.2
Loscalzo, J.3
-
35
-
-
0037780685
-
Effect of eplerenone, a selective aldosterone blocker, on blood pressure, serum and macrophage oxidative stress, and atherosclerosis in apolipoprotein E-deficient mice
-
12775976 1:CAS:528:DC%2BD3sXksVGju7c%3D 10.1097/00005344-200306000-00019
-
Keidar S, Hayek T, Kaplan M, Pavlotzky E, Hamoud S, Coleman R, Aviram M (2003) Effect of eplerenone, a selective aldosterone blocker, on blood pressure, serum and macrophage oxidative stress, and atherosclerosis in apolipoprotein E-deficient mice. J Cardiovasc Pharmacol 41(6):955-963
-
(2003)
J Cardiovasc Pharmacol
, vol.41
, Issue.6
, pp. 955-963
-
-
Keidar, S.1
Hayek, T.2
Kaplan, M.3
Pavlotzky, E.4
Hamoud, S.5
Coleman, R.6
Aviram, M.7
-
36
-
-
2442490850
-
Aldosterone administration to mice stimulates macrophage NADPH oxidase and increases atherosclerosis development: A possible role for angiotensin-converting enzyme and the receptors for angiotensin II and aldosterone
-
15123520 1:CAS:528:DC%2BD2cXjs1eis74%3D 10.1161/01.CIR.0000127949.05756. 9D
-
Keidar S, Kaplan M, Pavlotzky E, Coleman R, Hayek T, Hamoud S, Aviram M (2004) Aldosterone administration to mice stimulates macrophage NADPH oxidase and increases atherosclerosis development: a possible role for angiotensin-converting enzyme and the receptors for angiotensin II and aldosterone. Circulation 109(18):2213-2220
-
(2004)
Circulation
, vol.109
, Issue.18
, pp. 2213-2220
-
-
Keidar, S.1
Kaplan, M.2
Pavlotzky, E.3
Coleman, R.4
Hayek, T.5
Hamoud, S.6
Aviram, M.7
-
37
-
-
77952958303
-
Elevated mineralocorticoid receptor activity in aged rat vascular smooth muscle cells promotes a proinflammatory phenotype via extracellular signal-regulated kinase 1/2 mitogen-activated protein kinase and epidermal growth factor receptor-dependent pathways
-
20421514 1:CAS:528:DC%2BC3cXmt1alu78%3D 10.1161/HYPERTENSIONAHA.109. 148783
-
Krug AW, Allenhofer L, Monticone R, Spinetti G, Gekle M, Wang M, Lakatta EG (2010) Elevated mineralocorticoid receptor activity in aged rat vascular smooth muscle cells promotes a proinflammatory phenotype via extracellular signal-regulated kinase 1/2 mitogen-activated protein kinase and epidermal growth factor receptor-dependent pathways. Hypertension 55(6):1476-1483
-
(2010)
Hypertension
, vol.55
, Issue.6
, pp. 1476-1483
-
-
Krug, A.W.1
Allenhofer, L.2
Monticone, R.3
Spinetti, G.4
Gekle, M.5
Wang, M.6
Lakatta, E.G.7
-
38
-
-
0035131479
-
Prevention of aortic and cardiac fibrosis by spironolactone in old normotensive rats
-
11216994 1:CAS:528:DC%2BD3MXhsl2jurg%3D 10.1016/S0735-1097(00)01129-3
-
Lacolley P, Safar ME, Lucet B, Ledudal K, Labat C, Benetos A (2001) Prevention of aortic and cardiac fibrosis by spironolactone in old normotensive rats. J Am Coll Cardiol 37(2):662-667
-
(2001)
J Am Coll Cardiol
, vol.37
, Issue.2
, pp. 662-667
-
-
Lacolley, P.1
Safar, M.E.2
Lucet, B.3
Ledudal, K.4
Labat, C.5
Benetos, A.6
-
39
-
-
74949109381
-
Rapid aldosterone signaling and vascular reactivity: Relax or don't do it
-
19858736 1:CAS:528:DC%2BD1MXhsF2gsbnL 10.1097/FJC.0b013e3181c37ddc
-
Leopold JA (2009) Rapid aldosterone signaling and vascular reactivity: relax or don't do it. J Cardiovasc Pharmacol 54(6):465-467
-
(2009)
J Cardiovasc Pharmacol
, vol.54
, Issue.6
, pp. 465-467
-
-
Leopold, J.A.1
-
40
-
-
2942683383
-
Distinguishing the antihypertensive and electrolyte effects of eplerenone
-
15181050 1:CAS:528:DC%2BD2cXmtlGqur0%3D 10.1210/jc.2003-032149
-
Levy DG, Rocha R, Funder JW (2004) Distinguishing the antihypertensive and electrolyte effects of eplerenone. J Clin Endocrinol Metab 89(6):2736-2740
-
(2004)
J Clin Endocrinol Metab
, vol.89
, Issue.6
, pp. 2736-2740
-
-
Levy, D.G.1
Rocha, R.2
Funder, J.W.3
-
41
-
-
0034106595
-
Long-term angiotensin II type 1 receptor blockade with fonsartan doubles lifespan of hypertensive rats
-
10775560 1:CAS:528:DC%2BD3cXjtFWqu7k%3D 10.1161/01.HYP.35.4.908
-
Linz W, Heitsch H, Scholkens BA, Wiemer G (2000) Long-term angiotensin II type 1 receptor blockade with fonsartan doubles lifespan of hypertensive rats. Hypertension 35(4):908-913
-
(2000)
Hypertension
, vol.35
, Issue.4
, pp. 908-913
-
-
Linz, W.1
Heitsch, H.2
Scholkens, B.A.3
Wiemer, G.4
-
42
-
-
78650325348
-
Hypertension in aging patients
-
21166533 10.1586/erc.10.171
-
Logan AG (2011) Hypertension in aging patients. Expert Rev Cardiovasc Ther 9(1):113-120
-
(2011)
Expert Rev Cardiovasc Ther
, vol.9
, Issue.1
, pp. 113-120
-
-
Logan, A.G.1
-
43
-
-
0026689952
-
Immunohistochemical and biochemical evidence for a cardiovascular mineralocorticoid receptor
-
1323429 1:CAS:528:DyaK38Xls1Cis7k%3D 10.1161/01.RES.71.3.503
-
Lombes M, Oblin ME, Gasc JM, Baulieu EE, Farman N, Bonvalet JP (1992) Immunohistochemical and biochemical evidence for a cardiovascular mineralocorticoid receptor. Circ Res 71(3):503-510
-
(1992)
Circ Res
, vol.71
, Issue.3
, pp. 503-510
-
-
Lombes, M.1
Oblin, M.E.2
Gasc, J.M.3
Baulieu, E.E.4
Farman, N.5
Bonvalet, J.P.6
-
44
-
-
84859121214
-
Spironolactone lowers portal hypertension by inhibiting liver fibrosis, ROCK-2 activity and activating NO/PKG pathway in the bile-duct-ligated rat
-
22479572 1:CAS:528:DC%2BC38Xlslehtbc%3D 10.1371/journal.pone.0034230
-
Luo W, Meng Y, Ji HL, Pan CQ, Huang S, Yu CH, Xiao LM, Cui K, Ni SY, Zhang ZS et al (2012) Spironolactone lowers portal hypertension by inhibiting liver fibrosis, ROCK-2 activity and activating NO/PKG pathway in the bile-duct-ligated rat. PLoS One 7(3):e34230
-
(2012)
PLoS One
, vol.7
, Issue.3
, pp. 34230
-
-
Luo, W.1
Meng, Y.2
Ji, H.L.3
Pan, C.Q.4
Huang, S.5
Yu, C.H.6
Xiao, L.M.7
Cui, K.8
Ni, S.Y.9
Zhang, Z.S.10
-
45
-
-
84865790123
-
Aldosterone deficiency and mineralocorticoid receptor antagonism prevent angiotensin II-induced cardiac, renal, and vascular injury
-
22622494 1:CAS:528:DC%2BC38Xht1yqsr7O 10.1038/ki.2012.170
-
Luther JM, Luo P, Wang Z, Cohen SE, Kim HS, Fogo AB, Brown NJ (2012) Aldosterone deficiency and mineralocorticoid receptor antagonism prevent angiotensin II-induced cardiac, renal, and vascular injury. Kidney Int 82(6):643-651
-
(2012)
Kidney Int
, vol.82
, Issue.6
, pp. 643-651
-
-
Luther, J.M.1
Luo, P.2
Wang, Z.3
Cohen, S.E.4
Kim, H.S.5
Fogo, A.B.6
Brown, N.J.7
-
46
-
-
65549123191
-
Aldosterone increases oxidant stress to impair guanylyl cyclase activity by cysteinyl thiol oxidation in vascular smooth muscle cells
-
19141618 1:CAS:528:DC%2BD1MXjtVSmsb8%3D 10.1074/jbc.M809460200
-
Maron BA, Zhang YY, Handy DE, Beuve A, Tang SS, Loscalzo J, Leopold JA (2009) Aldosterone increases oxidant stress to impair guanylyl cyclase activity by cysteinyl thiol oxidation in vascular smooth muscle cells. J Biol Chem 284(12):7665-7672
-
(2009)
J Biol Chem
, vol.284
, Issue.12
, pp. 7665-7672
-
-
Maron, B.A.1
Zhang, Y.Y.2
Handy, D.E.3
Beuve, A.4
Tang, S.S.5
Loscalzo, J.6
Leopold, J.A.7
-
47
-
-
84856325649
-
Mineralocorticoid receptors in vascular function and disease
-
21723914 1:CAS:528:DC%2BC38Xhs1Giu7o%3D 10.1016/j.mce.2011.06.014
-
McCurley A, Jaffe IZ (2012) Mineralocorticoid receptors in vascular function and disease. Mol Cell Endocrinol 350(2):256-265
-
(2012)
Mol Cell Endocrinol
, vol.350
, Issue.2
, pp. 256-265
-
-
McCurley, A.1
Jaffe, I.Z.2
-
48
-
-
84868662652
-
Direct regulation of blood pressure by smooth muscle cell mineralocorticoid receptors
-
22922412 1:CAS:528:DC%2BC38Xht1GhsbnP 10.1038/nm.2891
-
McCurley A, Pires PW, Bender SB, Aronovitz M, Zhao MJ, Metzger D, Chambon P, Hill MA, Dorrance AM, Mendelsohn ME, Jaffe IZ (2012) Direct regulation of blood pressure by smooth muscle cell mineralocorticoid receptors. Nat Med 18(9):1429-1433
-
(2012)
Nat Med
, vol.18
, Issue.9
, pp. 1429-1433
-
-
McCurley, A.1
Pires, P.W.2
Bender, S.B.3
Aronovitz, M.4
Zhao, M.J.5
Metzger, D.6
Chambon, P.7
Hill, M.A.8
Dorrance, A.M.9
Mendelsohn, M.E.10
Jaffe, I.Z.11
-
49
-
-
84879499342
-
Aldosterone increases early atherosclerosis and promotes plaque inflammation through a placental growth factor-dependent mechanism
-
23525413
-
McGraw AP, Bagley J, Chen W, Galayda C, Nickerson H, Armani A, Caprio M, Carmeliet P, Jaffe IZ (2013) Aldosterone increases early atherosclerosis and promotes plaque inflammation through a placental growth factor-dependent mechanism. J Am Heart Assoc 2:e000018
-
(2013)
J Am Heart Assoc
, vol.2
, pp. 000018
-
-
McGraw, A.P.1
Bagley, J.2
Chen, W.3
Galayda, C.4
Nickerson, H.5
Armani, A.6
Caprio, M.7
Carmeliet, P.8
Jaffe, I.Z.9
-
50
-
-
16844382180
-
In hypertension, the kidney is not always the heart of the matter
-
15841174 1:CAS:528:DC%2BD2MXjtFylsbc%3D
-
Mendelsohn ME (2005) In hypertension, the kidney is not always the heart of the matter. J Clin Invest 115(4):840-844
-
(2005)
J Clin Invest
, vol.115
, Issue.4
, pp. 840-844
-
-
Mendelsohn, M.E.1
-
51
-
-
14244263221
-
Eplerenone blocks nongenomic effects of aldosterone on the Na+/H + exchanger, intracellular Ca2+ levels, and vasoconstriction in mesenteric resistance vessels
-
15550504 1:CAS:528:DC%2BD2MXitlehs70%3D 10.1210/en.2004-1130
-
Michea L, Delpiano AM, Hitschfeld C, Lobos L, Lavandero S, Marusic ET (2005) Eplerenone blocks nongenomic effects of aldosterone on the Na+/H + exchanger, intracellular Ca2+ levels, and vasoconstriction in mesenteric resistance vessels. Endocrinology 146(3):973-980
-
(2005)
Endocrinology
, vol.146
, Issue.3
, pp. 973-980
-
-
Michea, L.1
Delpiano, A.M.2
Hitschfeld, C.3
Lobos, L.4
Lavandero, S.5
Marusic, E.T.6
-
52
-
-
17144421237
-
Evidence for an increased rate of cardiovascular events in patients with primary aldosteronism
-
15837256 1:CAS:528:DC%2BD2MXjtlagt70%3D 10.1016/j.jacc.2005.01.015
-
Milliez P, Girerd X, Plouin PF, Blacher J, Safar ME, Mourad JJ (2005) Evidence for an increased rate of cardiovascular events in patients with primary aldosteronism. J Am Coll Cardiol 45(8):1243-1248
-
(2005)
J Am Coll Cardiol
, vol.45
, Issue.8
, pp. 1243-1248
-
-
Milliez, P.1
Girerd, X.2
Plouin, P.F.3
Blacher, J.4
Safar, M.E.5
Mourad, J.J.6
-
53
-
-
24744471859
-
Aldosterone and angiotensin II synergistically induce mitogenic response in vascular smooth muscle cells
-
16081869 1:CAS:528:DC%2BD2MXpsVWrtbw%3D 10.1161/01.RES.0000180753.63183. 95
-
Min LJ, Mogi M, Li JM, Iwanami J, Iwai M, Horiuchi M (2005) Aldosterone and angiotensin II synergistically induce mitogenic response in vascular smooth muscle cells. Circ Res 97(5):434-442
-
(2005)
Circ Res
, vol.97
, Issue.5
, pp. 434-442
-
-
Min, L.J.1
Mogi, M.2
Li, J.M.3
Iwanami, J.4
Iwai, M.5
Horiuchi, M.6
-
54
-
-
31544473558
-
Aldosterone stimulates reactive oxygen species production through activation of NADPH oxidase in rat mesangial cells
-
16135774 1:CAS:528:DC%2BD2MXhtFegtLnM 10.1681/ASN.2005040390
-
Miyata K, Rahman M, Shokoji T, Nagai Y, Zhang GX, Sun GP, Kimura S, Yukimura T, Kiyomoto H, Kohno M et al (2005) Aldosterone stimulates reactive oxygen species production through activation of NADPH oxidase in rat mesangial cells. J Am Soc Nephrol 16(10):2906-2912
-
(2005)
J Am Soc Nephrol
, vol.16
, Issue.10
, pp. 2906-2912
-
-
Miyata, K.1
Rahman, M.2
Shokoji, T.3
Nagai, Y.4
Zhang, G.X.5
Sun, G.P.6
Kimura, S.7
Yukimura, T.8
Kiyomoto, H.9
Kohno, M.10
-
55
-
-
52449122086
-
Aldosterone and angiotensin II synergistically stimulate migration in vascular smooth muscle cells through c-Src-regulated redox-sensitive RhoA pathways
-
18467645 1:CAS:528:DC%2BD1cXosVerurk%3D 10.1161/ATVBAHA.108.168021
-
Montezano AC, Callera GE, Yogi A, He Y, Tostes RC, He G, Schiffrin EL, Touyz RM (2008) Aldosterone and angiotensin II synergistically stimulate migration in vascular smooth muscle cells through c-Src-regulated redox-sensitive RhoA pathways. Arterioscler Thromb Vasc Biol 28(8):1511-1518
-
(2008)
Arterioscler Thromb Vasc Biol
, vol.28
, Issue.8
, pp. 1511-1518
-
-
Montezano, A.C.1
Callera, G.E.2
Yogi, A.3
He, Y.4
Tostes, R.C.5
He, G.6
Schiffrin, E.L.7
Touyz, R.M.8
-
56
-
-
0032514605
-
Increased carotid artery intimal-medial thickness in asymptomatic older subjects with exercise-induced myocardial ischemia
-
9769303 1:STN:280:DyaK1cvktlCqtQ%3D%3D 10.1161/01.CIR.98.15.1504
-
Nagai Y, Metter EJ, Earley CJ, Kemper MK, Becker LC, Lakatta EG, Fleg JL (1998) Increased carotid artery intimal-medial thickness in asymptomatic older subjects with exercise-induced myocardial ischemia. Circulation 98(15):1504-1509
-
(1998)
Circulation
, vol.98
, Issue.15
, pp. 1504-1509
-
-
Nagai, Y.1
Metter, E.J.2
Earley, C.J.3
Kemper, M.K.4
Becker, L.C.5
Lakatta, E.G.6
Fleg, J.L.7
-
57
-
-
33744981628
-
Podocyte injury underlies the glomerulopathy of Dahl salt-hypertensive rats and is reversed by aldosterone blocker
-
16636193 1:CAS:528:DC%2BD28XksVOmu7g%3D 10.1161/01.HYP.0000222003.28517. 99
-
Nagase M, Shibata S, Yoshida S, Nagase T, Gotoda T, Fujita T (2006) Podocyte injury underlies the glomerulopathy of Dahl salt-hypertensive rats and is reversed by aldosterone blocker. Hypertension 47(6):1084-1093
-
(2006)
Hypertension
, vol.47
, Issue.6
, pp. 1084-1093
-
-
Nagase, M.1
Shibata, S.2
Yoshida, S.3
Nagase, T.4
Gotoda, T.5
Fujita, T.6
-
58
-
-
33645816971
-
Mineralocorticoid receptor antagonism attenuates cardiac hypertrophy and failure in low-aldosterone hypertensive rats
-
16505208 1:CAS:528:DC%2BD28XitlSgtLo%3D 10.1161/01.HYP.0000203772.78696. 67
-
Nagata K, Obata K, Xu J, Ichihara S, Noda A, Kimata H, Kato T, Izawa H, Murohara T, Yokota M (2006) Mineralocorticoid receptor antagonism attenuates cardiac hypertrophy and failure in low-aldosterone hypertensive rats. Hypertension 47(4):656-664
-
(2006)
Hypertension
, vol.47
, Issue.4
, pp. 656-664
-
-
Nagata, K.1
Obata, K.2
Xu, J.3
Ichihara, S.4
Noda, A.5
Kimata, H.6
Kato, T.7
Izawa, H.8
Murohara, T.9
Yokota, M.10
-
59
-
-
84856505776
-
Antihypertensive and cardiorenal protective effects of SM-368229, a novel mineralocorticoid receptor antagonist, in aldosterone/salt-treated rats
-
22302095 1:CAS:528:DC%2BC38Xkt1CrtLo%3D 10.1159/000335559
-
Nariai T, Fujita K, Mori M, Katayama S, Hori S, Matsui K (2012) Antihypertensive and cardiorenal protective effects of SM-368229, a novel mineralocorticoid receptor antagonist, in aldosterone/salt-treated rats. Pharmacology 89(1-2):44-52
-
(2012)
Pharmacology
, vol.89
, Issue.1-2
, pp. 44-52
-
-
Nariai, T.1
Fujita, K.2
Mori, M.3
Katayama, S.4
Hori, S.5
Matsui, K.6
-
60
-
-
84861098413
-
SM-368229, a novel promising mineralocorticoid receptor antagonist, shows antihypertensive efficacy with minimal effect on serum potassium level in rats
-
22240917 1:CAS:528:DC%2BC38XmsFOjtr0%3D 10.1097/FJC.0b013e3182495543
-
Nariai T, Fujita K, Mori M, Katayama S, Hori S, Matsui K (2012) SM-368229, a novel promising mineralocorticoid receptor antagonist, shows antihypertensive efficacy with minimal effect on serum potassium level in rats. J Cardiovasc Pharmacol 59(5):458-464
-
(2012)
J Cardiovasc Pharmacol
, vol.59
, Issue.5
, pp. 458-464
-
-
Nariai, T.1
Fujita, K.2
Mori, M.3
Katayama, S.4
Hori, S.5
Matsui, K.6
-
61
-
-
80051552165
-
Aldosterone regulates vascular gene transcription via oxidative stress-dependent and -independent pathways
-
21617142 1:CAS:528:DC%2BC3MXptFCmsr8%3D 10.1161/ATVBAHA.111.229070
-
Newfell BG, Iyer LK, Mohammad NN, McGraw AP, Ehsan A, Rosano G, Huang PL, Mendelsohn ME, Jaffe IZ (2011) Aldosterone regulates vascular gene transcription via oxidative stress-dependent and -independent pathways. Arterioscler Thromb Vasc Biol 31(8):1871-1880
-
(2011)
Arterioscler Thromb Vasc Biol
, vol.31
, Issue.8
, pp. 1871-1880
-
-
Newfell, B.G.1
Iyer, L.K.2
Mohammad, N.N.3
McGraw, A.P.4
Ehsan, A.5
Rosano, G.6
Huang, P.L.7
Mendelsohn, M.E.8
Jaffe, I.Z.9
-
62
-
-
0033531215
-
Carotid-artery intima and media thickness as a risk factor for myocardial infarction and stroke in older adults. Cardiovascular Health Study Collaborative Research Group
-
9878640 10.1056/NEJM199901073400103
-
O'Leary DH, Polak JF, Kronmal RA, Manolio TA, Burke GL, Wolfson SK Jr (1999) Carotid-artery intima and media thickness as a risk factor for myocardial infarction and stroke in older adults. Cardiovascular Health Study Collaborative Research Group. N Engl J Med 340(1):14-22
-
(1999)
N Engl J Med
, vol.340
, Issue.1
, pp. 14-22
-
-
O'Leary, D.H.1
Polak, J.F.2
Kronmal, R.A.3
Manolio, T.A.4
Burke, G.L.5
Wolfson, Jr.S.K.6
-
63
-
-
77951297553
-
Progenitor cell-derived smooth muscle cells in vascular disease
-
20117099 1:CAS:528:DC%2BC3cXks1Wnu78%3D 10.1016/j.bcp.2010.01.027
-
Orlandi A, Bennett M (2010) Progenitor cell-derived smooth muscle cells in vascular disease. Biochem Pharmacol 79(12):1706-1713
-
(2010)
Biochem Pharmacol
, vol.79
, Issue.12
, pp. 1706-1713
-
-
Orlandi, A.1
Bennett, M.2
-
64
-
-
70350159878
-
Complex regulation and function of the inflammatory smooth muscle cell phenotype in atherosclerosis
-
19851078 10.1159/000250095
-
Orr AW, Hastings NE, Blackman BR, Wamhoff BR (2010) Complex regulation and function of the inflammatory smooth muscle cell phenotype in atherosclerosis. J Vasc Res 47(2):168-180
-
(2010)
J Vasc Res
, vol.47
, Issue.2
, pp. 168-180
-
-
Orr, A.W.1
Hastings, N.E.2
Blackman, B.R.3
Wamhoff, B.R.4
-
65
-
-
0034916015
-
The EPHESUS trial: Eplerenone in patients with heart failure due to systolic dysfunction complicating acute myocardial infarction. Eplerenone Post-AMI Heart Failure Efficacy and Survival Study
-
11504167 1:CAS:528:DC%2BD3MXmt1Sjs70%3D 10.1023/A:1011119003788
-
Pitt B, Williams G, Remme W, Martinez F, Lopez-Sendon J, Zannad F, Neaton J, Roniker B, Hurley S, Burns D et al (2001) The EPHESUS trial: eplerenone in patients with heart failure due to systolic dysfunction complicating acute myocardial infarction. Eplerenone Post-AMI Heart Failure Efficacy and Survival Study. Cardiovasc Drugs Ther 15(1):79-87
-
(2001)
Cardiovasc Drugs Ther
, vol.15
, Issue.1
, pp. 79-87
-
-
Pitt, B.1
Williams, G.2
Remme, W.3
Martinez, F.4
Lopez-Sendon, J.5
Zannad, F.6
Neaton, J.7
Roniker, B.8
Hurley, S.9
Burns, D.10
-
66
-
-
0033517302
-
The effect of spironolactone on morbidity and mortality in patients with severe heart failure. Randomized Aldactone Evaluation Study Investigators
-
10471456 1:CAS:528:DyaK1MXmtVyrurk%3D 10.1056/NEJM199909023411001
-
Pitt B, Zannad F, Remme WJ, Cody R, Castaigne A, Perez A, Palensky J, Wittes J (1999) The effect of spironolactone on morbidity and mortality in patients with severe heart failure. Randomized Aldactone Evaluation Study Investigators. N Engl J Med 341(10):709-717
-
(1999)
N Engl J Med
, vol.341
, Issue.10
, pp. 709-717
-
-
Pitt, B.1
Zannad, F.2
Remme, W.J.3
Cody, R.4
Castaigne, A.5
Perez, A.6
Palensky, J.7
Wittes, J.8
-
67
-
-
0038141826
-
Endothelin antagonism on aldosterone-induced oxidative stress and vascular remodeling
-
12782645 1:CAS:528:DC%2BD3sXkvVKmtrk%3D 10.1161/01.HYP.0000078357.92682. EC
-
Pu Q, Neves MF, Virdis A, Touyz RM, Schiffrin EL (2003) Endothelin antagonism on aldosterone-induced oxidative stress and vascular remodeling. Hypertension 42(1):49-55
-
(2003)
Hypertension
, vol.42
, Issue.1
, pp. 49-55
-
-
Pu, Q.1
Neves, M.F.2
Virdis, A.3
Touyz, R.M.4
Schiffrin, E.L.5
-
68
-
-
0037035471
-
Mineralocorticoid receptor antagonism in experimental atherosclerosis
-
11994257 1:CAS:528:DC%2BD38XktlOku7Y%3D 10.1161/01.CIR.0000015854.60710. 10
-
Rajagopalan S, Duquaine D, King S, Pitt B, Patel P (2002) Mineralocorticoid receptor antagonism in experimental atherosclerosis. Circulation 105(18):2212-2216
-
(2002)
Circulation
, vol.105
, Issue.18
, pp. 2212-2216
-
-
Rajagopalan, S.1
Duquaine, D.2
King, S.3
Pitt, B.4
Patel, P.5
-
69
-
-
79959871432
-
Cross-talk between aldosterone and angiotensin signaling in vascular smooth muscle cells
-
21371487 1:CAS:528:DC%2BC3MXosFWqtbc%3D
-
Rautureau Y, Paradis P, Schiffrin EL (2011) Cross-talk between aldosterone and angiotensin signaling in vascular smooth muscle cells. Steroids 76(9):834-839
-
(2011)
Steroids
, vol.76
, Issue.9
, pp. 834-839
-
-
Rautureau, Y.1
Paradis, P.2
Schiffrin, E.L.3
-
70
-
-
84871530951
-
Eplerenone reduced lesion size in early but not advanced atherosclerosis in apolipoprotein E-deficient mice
-
23232789 1:CAS:528:DC%2BC38XhvVWgsLrF 10.1097/FJC.0b013e31826f5535
-
Raz-Pasteur A, Gamliel-Lazarovich A, Coleman R, Keidar S (2012) Eplerenone reduced lesion size in early but not advanced atherosclerosis in apolipoprotein E-deficient mice. J Cardiovasc Pharmacol 60(6):508-512
-
(2012)
J Cardiovasc Pharmacol
, vol.60
, Issue.6
, pp. 508-512
-
-
Raz-Pasteur, A.1
Gamliel-Lazarovich, A.2
Coleman, R.3
Keidar, S.4
-
71
-
-
84869089106
-
Effects of aldosterone on human atherosclerosis: Plasma aldosterone and progression of carotid plaque
-
22717248 10.1016/j.cjca.2012.04.014
-
Rita OD, Hackam DG, Spence JD (2012) Effects of aldosterone on human atherosclerosis: plasma aldosterone and progression of carotid plaque. Can J Cardiol 28:706-711
-
(2012)
Can J Cardiol
, vol.28
, pp. 706-711
-
-
Rita, O.D.1
Hackam, D.G.2
Spence, J.D.3
-
72
-
-
0029907125
-
Vascular hypertrophy and remodeling in secondary hypertension
-
8901824 1:STN:280:DyaK2s%2FlslCrtw%3D%3D 10.1161/01.HYP.28.5.785
-
Rizzoni D, Porteri E, Castellano M, Bettoni G, Muiesan ML, Muiesan P, Giulini SM, Agabiti-Rosei E (1996) Vascular hypertrophy and remodeling in secondary hypertension. Hypertension 28(5):785-790
-
(1996)
Hypertension
, vol.28
, Issue.5
, pp. 785-790
-
-
Rizzoni, D.1
Porteri, E.2
Castellano, M.3
Bettoni, G.4
Muiesan, M.L.5
Muiesan, P.6
Giulini, S.M.7
Agabiti-Rosei, E.8
-
73
-
-
78651461701
-
HRG inhibits tumor growth and metastasis by inducing macrophage polarization and vessel normalization through downregulation of PlGF
-
21215706 1:CAS:528:DC%2BC3MXpvValtw%3D%3D 10.1016/j.ccr.2010.11.009
-
Rolny C, Mazzone M, Tugues S, Laoui D, Johansson I, Coulon C, Squadrito ML, Segura I, Li X, Knevels E et al (2011) HRG inhibits tumor growth and metastasis by inducing macrophage polarization and vessel normalization through downregulation of PlGF. Cancer Cell 19(1):31-44
-
(2011)
Cancer Cell
, vol.19
, Issue.1
, pp. 31-44
-
-
Rolny, C.1
Mazzone, M.2
Tugues, S.3
Laoui, D.4
Johansson, I.5
Coulon, C.6
Squadrito, M.L.7
Segura, I.8
Li, X.9
Knevels, E.10
-
74
-
-
77949380586
-
Short-term delivery of anti-PlGF antibody delays progression of atherosclerotic plaques to vulnerable lesions
-
19952000 1:CAS:528:DC%2BC3cXjt1GitLY%3D 10.1093/cvr/cvp380
-
Roncal C, Buysschaert I, Gerdes N, Georgiadou M, Ovchinnikova O, Fischer C, Stassen JM, Moons L, Collen D, De Bock K et al (2010) Short-term delivery of anti-PlGF antibody delays progression of atherosclerotic plaques to vulnerable lesions. Cardiovasc Res 86(1):29-36
-
(2010)
Cardiovasc Res
, vol.86
, Issue.1
, pp. 29-36
-
-
Roncal, C.1
Buysschaert, I.2
Gerdes, N.3
Georgiadou, M.4
Ovchinnikova, O.5
Fischer, C.6
Stassen, J.M.7
Moons, L.8
Collen, D.9
De Bock, K.10
-
75
-
-
34249897753
-
Impairment of sodium balance in mice deficient in renal principal cell mineralocorticoid receptor
-
17475815 1:CAS:528:DC%2BD2sXnt1Squro%3D 10.1681/ASN.2006090975
-
Ronzaud C, Loffing J, Bleich M, Gretz N, Grone HJ, Schutz G, Berger S (2007) Impairment of sodium balance in mice deficient in renal principal cell mineralocorticoid receptor. J Am Soc Nephrol 18(6):1679-1687
-
(2007)
J Am Soc Nephrol
, vol.18
, Issue.6
, pp. 1679-1687
-
-
Ronzaud, C.1
Loffing, J.2
Bleich, M.3
Gretz, N.4
Grone, H.J.5
Schutz, G.6
Berger, S.7
-
76
-
-
79954567190
-
Inducible renal principal cell-specific mineralocorticoid receptor gene inactivation in mice
-
21383102 1:CAS:528:DC%2BC3MXjs1Gqtbg%3D 10.1152/ajprenal.00728.2009
-
Ronzaud C, Loffing J, Gretz N, Schutz G, Berger S (2011) Inducible renal principal cell-specific mineralocorticoid receptor gene inactivation in mice. Am J Physiol Renal Physiol 300(3):F756-F760
-
(2011)
Am J Physiol Renal Physiol
, vol.300
, Issue.3
-
-
Ronzaud, C.1
Loffing, J.2
Gretz, N.3
Schutz, G.4
Berger, S.5
-
77
-
-
20844455790
-
Participation of aldosterone in the vascular inflammatory response of spontaneously hypertensive rats: Role of the NFkappaB/IkappaB system
-
15894892 1:CAS:528:DC%2BD2MXktFynsbw%3D 10.1097/01.hjh.0000170379.08214. 5a
-
Sanz-Rosa D, Cediel E, de las Heras N, Miana M, Balfagon G, Lahera V, Cachofeiro V (2005) Participation of aldosterone in the vascular inflammatory response of spontaneously hypertensive rats: role of the NFkappaB/IkappaB system. J Hypertens 23(6):1167-1172
-
(2005)
J Hypertens
, vol.23
, Issue.6
, pp. 1167-1172
-
-
Sanz-Rosa, D.1
Cediel, E.2
De Las Heras, N.3
Miana, M.4
Balfagon, G.5
Lahera, V.6
Cachofeiro, V.7
-
78
-
-
24144490658
-
Eplerenone reduces oxidative stress and enhances eNOS in SHR: Vascular functional and structural consequences
-
16115035 1:CAS:528:DC%2BD2MXos1erurg%3D 10.1089/ars.2005.7.1294
-
Sanz-Rosa D, Oubina MP, Cediel E, De las Heras N, Aragoncillo P, Balfagon G, Cachofeiro V, Lahera V (2005) Eplerenone reduces oxidative stress and enhances eNOS in SHR: vascular functional and structural consequences. Antioxid Redox Signal 7(9-10):1294-1301
-
(2005)
Antioxid Redox Signal
, vol.7
, Issue.9-10
, pp. 1294-1301
-
-
Sanz-Rosa, D.1
Oubina, M.P.2
Cediel, E.3
De Las Heras, N.4
Aragoncillo, P.5
Balfagon, G.6
Cachofeiro, V.7
Lahera, V.8
-
79
-
-
0028043535
-
Signal transduction and regulation in smooth muscle
-
7969467 1:CAS:528:DyaK2MXit1Oqs7g%3D 10.1038/372231a0
-
Somlyo AP, Somlyo AV (1994) Signal transduction and regulation in smooth muscle. Nature 372(6503):231-236
-
(1994)
Nature
, vol.372
, Issue.6503
, pp. 231-236
-
-
Somlyo, A.P.1
Somlyo, A.V.2
-
80
-
-
80053474914
-
Vascular stiffness and increased pulse pressure in the aging cardiovascular system
-
21845218
-
Steppan J, Barodka V, Berkowitz DE, Nyhan D (2011) Vascular stiffness and increased pulse pressure in the aging cardiovascular system. Cardiol Res Pract 2011:263585
-
(2011)
Cardiol Res Pract
, vol.2011
, pp. 263585
-
-
Steppan, J.1
Barodka, V.2
Berkowitz, D.E.3
Nyhan, D.4
-
81
-
-
79955563776
-
Fatal and nonfatal outcomes, incidence of hypertension, and blood pressure changes in relation to urinary sodium excretion
-
21540421 1:CAS:528:DC%2BC3MXlslyqurY%3D 10.1001/jama.2011.574
-
Stolarz-Skrzypek K, Kuznetsova T, Thijs L, Tikhonoff V, Seidlerova J, Richart T, Jin Y, Olszanecka A, Malyutina S, Casiglia E et al (2011) Fatal and nonfatal outcomes, incidence of hypertension, and blood pressure changes in relation to urinary sodium excretion. JAMA 305(17):1777-1785
-
(2011)
JAMA
, vol.305
, Issue.17
, pp. 1777-1785
-
-
Stolarz-Skrzypek, K.1
Kuznetsova, T.2
Thijs, L.3
Tikhonoff, V.4
Seidlerova, J.5
Richart, T.6
Jin, Y.7
Olszanecka, A.8
Malyutina, S.9
Casiglia, E.10
-
82
-
-
79960553999
-
Reduced dietary salt for the prevention of cardiovascular disease: A meta-analysis of randomized controlled trials (Cochrane review)
-
21731062 1:CAS:528:DC%2BC3MXovFOht7g%3D 10.1038/ajh.2011.115
-
Taylor RS, Ashton KE, Moxham T, Hooper L, Ebrahim S (2011) Reduced dietary salt for the prevention of cardiovascular disease: a meta-analysis of randomized controlled trials (Cochrane review). Am J Hypertens 24(8):843-853
-
(2011)
Am J Hypertens
, vol.24
, Issue.8
, pp. 843-853
-
-
Taylor, R.S.1
Ashton, K.E.2
Moxham, T.3
Hooper, L.4
Ebrahim, S.5
-
83
-
-
77956938607
-
Mechanisms of vascular aging: New perspectives
-
20576649 10.1093/gerona/glq113
-
Ungvari Z, Kaley G, de Cabo R, Sonntag WE, Csiszar A (2010) Mechanisms of vascular aging: new perspectives. J Gerontol A Biol Sci Med Sci 65(10):1028-1041
-
(2010)
J Gerontol A Biol Sci Med Sci
, vol.65
, Issue.10
, pp. 1028-1041
-
-
Ungvari, Z.1
Kaley, G.2
De Cabo, R.3
Sonntag, W.E.4
Csiszar, A.5
-
84
-
-
0028890773
-
Neointimal thickening after balloon denudation is enhanced by aldosterone and inhibited by spironolactone, and aldosterone antagonist
-
7895235 1:CAS:528:DyaK2MXktVeisrk%3D 10.1016/S0008-6363(96)88542-7
-
Van Belle E, Bauters C, Wernert N, Hamon M, McFadden EP, Racadot A, Dupuis B, Lablanche JM, Bertrand ME (1995) Neointimal thickening after balloon denudation is enhanced by aldosterone and inhibited by spironolactone, and aldosterone antagonist. Cardiovasc Res 29(1):27-32
-
(1995)
Cardiovasc Res
, vol.29
, Issue.1
, pp. 27-32
-
-
Van Belle, E.1
Bauters, C.2
Wernert, N.3
Hamon, M.4
McFadden, E.P.5
Racadot, A.6
Dupuis, B.7
Lablanche, J.M.8
Bertrand, M.E.9
-
85
-
-
77949881587
-
Expanding view of aldosterone action, with an emphasis on rapid action
-
20409082 1:CAS:528:DC%2BC3cXltFSmtbY%3D 10.1111/j.1440-1681.2010.05352.x
-
Vinson GP, Coghlan JP (2010) Expanding view of aldosterone action, with an emphasis on rapid action. Clin Exp Pharmacol Physiol 37(4):410-416
-
(2010)
Clin Exp Pharmacol Physiol
, vol.37
, Issue.4
, pp. 410-416
-
-
Vinson, G.P.1
Coghlan, J.P.2
-
86
-
-
0036791717
-
Spironolactone improves angiotensin-induced vascular changes and oxidative stress
-
12364354 1:CAS:528:DC%2BD38Xntlams7Y%3D 10.1161/01.HYP.0000034738.79310. 06
-
Virdis A, Neves MF, Amiri F, Viel E, Touyz RM, Schiffrin EL (2002) Spironolactone improves angiotensin-induced vascular changes and oxidative stress. Hypertension 40(4):504-510
-
(2002)
Hypertension
, vol.40
, Issue.4
, pp. 504-510
-
-
Virdis, A.1
Neves, M.F.2
Amiri, F.3
Viel, E.4
Touyz, R.M.5
Schiffrin, E.L.6
-
87
-
-
77955728969
-
A randomized, double-blind, placebo-controlled trial of spironolactone on carotid intima-media thickness in nondiabetic hemodialysis patients
-
20522535 1:CAS:528:DC%2BC3cXhtFCru7nJ 10.2215/CJN.09421209
-
Vukusich A, Kunstmann S, Varela C, Gainza D, Bravo S, Sepulveda D, Cavada G, Michea L, Marusic ET (2010) A randomized, double-blind, placebo-controlled trial of spironolactone on carotid intima-media thickness in nondiabetic hemodialysis patients. Clin J Am Soc Nephrol 5(8):1380-1387
-
(2010)
Clin J Am Soc Nephrol
, vol.5
, Issue.8
, pp. 1380-1387
-
-
Vukusich, A.1
Kunstmann, S.2
Varela, C.3
Gainza, D.4
Bravo, S.5
Sepulveda, D.6
Cavada, G.7
Michea, L.8
Marusic, E.T.9
-
88
-
-
30444454826
-
Eplerenone suppresses neointimal formation after coronary stent implantation in swine
-
16023229 10.1016/j.ijcard.2005.03.078
-
Wakabayashi K, Suzuki H, Sato T, Iso Y, Katagiri T, Takeyama Y (2006) Eplerenone suppresses neointimal formation after coronary stent implantation in swine. Int J Cardiol 107(2):260-266
-
(2006)
Int J Cardiol
, vol.107
, Issue.2
, pp. 260-266
-
-
Wakabayashi, K.1
Suzuki, H.2
Sato, T.3
Iso, Y.4
Katagiri, T.5
Takeyama, Y.6
-
89
-
-
0038119606
-
Aging increases aortic MMP-2 activity and angiotensin II in nonhuman primates
-
12743015 1:CAS:528:DC%2BD3sXktVynu7w%3D 10.1161/01.HYP.0000073843.56046. 45
-
Wang M, Takagi G, Asai K, Resuello RG, Natividad FF, Vatner DE, Vatner SF, Lakatta EG (2003) Aging increases aortic MMP-2 activity and angiotensin II in nonhuman primates. Hypertension 41(6):1308-1316
-
(2003)
Hypertension
, vol.41
, Issue.6
, pp. 1308-1316
-
-
Wang, M.1
Takagi, G.2
Asai, K.3
Resuello, R.G.4
Natividad, F.F.5
Vatner, D.E.6
Vatner, S.F.7
Lakatta, E.G.8
-
90
-
-
34250816941
-
Proinflammatory profile within the grossly normal aged human aortic wall
-
17452499 1:CAS:528:DC%2BD2sXmtlKru7g%3D 10.1161/HYPERTENSIONAHA.107. 089409
-
Wang M, Zhang J, Jiang LQ, Spinetti G, Pintus G, Monticone R, Kolodgie FD, Virmani R, Lakatta EG (2007) Proinflammatory profile within the grossly normal aged human aortic wall. Hypertension 50(1):219-227
-
(2007)
Hypertension
, vol.50
, Issue.1
, pp. 219-227
-
-
Wang, M.1
Zhang, J.2
Jiang, L.Q.3
Spinetti, G.4
Pintus, G.5
Monticone, R.6
Kolodgie, F.D.7
Virmani, R.8
Lakatta, E.G.9
-
91
-
-
0035943051
-
Eplerenone suppresses constrictive remodeling and collagen accumulation after angioplasty in porcine coronary arteries
-
11468211 1:CAS:528:DC%2BD3MXmtFerur4%3D 10.1161/hc3001.091458
-
Ward MR, Kanellakis P, Ramsey D, Funder J, Bobik A (2001) Eplerenone suppresses constrictive remodeling and collagen accumulation after angioplasty in porcine coronary arteries. Circulation 104(4):467-472
-
(2001)
Circulation
, vol.104
, Issue.4
, pp. 467-472
-
-
Ward, M.R.1
Kanellakis, P.2
Ramsey, D.3
Funder, J.4
Bobik, A.5
-
92
-
-
84863982468
-
Nongenomic actions of aldosterone and progesterone revisited
-
22285849 1:CAS:528:DC%2BC38XhtVekt7zO 10.1016/j.steroids.2011.12.023
-
Wendler A, Albrecht C, Wehling M (2012) Nongenomic actions of aldosterone and progesterone revisited. Steroids 77(10):1002-1006
-
(2012)
Steroids
, vol.77
, Issue.10
, pp. 1002-1006
-
-
Wendler, A.1
Albrecht, C.2
Wehling, M.3
-
93
-
-
84864815314
-
Vascular disturbances in primary aldosteronism: Clinical evidence
-
22890049 10.1159/000340031
-
Widimsky J Jr, Strauch B, Petrak O, Rosa J, Somloova Z, Zelinka T, Holaj R (2012) Vascular disturbances in primary aldosteronism: clinical evidence. Kidney Blood Press Res 35(6):529-533
-
(2012)
Kidney Blood Press Res
, vol.35
, Issue.6
, pp. 529-533
-
-
Widimsky, Jr.J.1
Strauch, B.2
Petrak, O.3
Rosa, J.4
Somloova, Z.5
Zelinka, T.6
Holaj, R.7
-
94
-
-
84862914035
-
Endogenous aldosterone is involved in vascular calcification in rat
-
1:CAS:528:DC%2BC38Xislens7Y%3D 10.1258/ebm.2011.011175
-
Wu SY, Yu YR, Cai Y, Jia LX, Wang X, Xiao CS, Tang CS, Qi YF (2012) Endogenous aldosterone is involved in vascular calcification in rat. Exp Biol Med (Maywood) 237(1):31-37
-
(2012)
Exp Biol Med (Maywood)
, vol.237
, Issue.1
, pp. 31-37
-
-
Wu, S.Y.1
Yu, Y.R.2
Cai, Y.3
Jia, L.X.4
Wang, X.5
Xiao, C.S.6
Tang, C.S.7
Qi, Y.F.8
-
95
-
-
0034038579
-
Aldosterone mediates angiotensin II-stimulated rat vascular smooth muscle cell proliferation
-
10810318 1:CAS:528:DC%2BD3cXjvFegtbw%3D 10.1677/joe.0.1650533
-
Xiao F, Puddefoot JR, Vinson GP (2000) Aldosterone mediates angiotensin II-stimulated rat vascular smooth muscle cell proliferation. J Endocrinol 165(2):533-536
-
(2000)
J Endocrinol
, vol.165
, Issue.2
, pp. 533-536
-
-
Xiao, F.1
Puddefoot, J.R.2
Vinson, G.P.3
-
96
-
-
78650399880
-
Eplerenone in patients with systolic heart failure and mild symptoms
-
Group E-HS 21073363 1:CAS:528:DC%2BC3MXisValuw%3D%3D 10.1056/ NEJMoa1009492
-
Zannad F, McMurray JJ, Krum H, van Veldhuisen DJ, Swedberg K, Shi H, Vincent J, Pocock SJ, Pitt B, Group E-HS (2011) Eplerenone in patients with systolic heart failure and mild symptoms. N Engl J Med 364(1):11-21
-
(2011)
N Engl J Med
, vol.364
, Issue.1
, pp. 11-21
-
-
Zannad, F.1
McMurray, J.J.2
Krum, H.3
Van Veldhuisen, D.J.4
Swedberg, K.5
Shi, H.6
Vincent, J.7
Pocock, S.J.8
Pitt, B.9
-
97
-
-
82455212598
-
Chronic antagonism of the mineralocorticoid receptor ameliorates hypertension and end organ damage in a rodent model of salt-sensitive hypertension
-
21950654 1:CAS:528:DC%2BC3MXhsFertLzP 10.3109/10641963.2011.566956
-
Zhou X, Crook MF, Sharif-Rodriguez W, Zhu Y, Ruben Z, Pan Y, Urosevic-Price O, Wang L, Flattery AM, Forrest G et al (2011) Chronic antagonism of the mineralocorticoid receptor ameliorates hypertension and end organ damage in a rodent model of salt-sensitive hypertension. Clin Exp Hypertens 33(8):538-547
-
(2011)
Clin Exp Hypertens
, vol.33
, Issue.8
, pp. 538-547
-
-
Zhou, X.1
Crook, M.F.2
Sharif-Rodriguez, W.3
Zhu, Y.4
Ruben, Z.5
Pan, Y.6
Urosevic-Price, O.7
Wang, L.8
Flattery, A.M.9
Forrest, G.10
|