Aldosterone increases early atherosclerosis and promotes plaque inflammation through a placental growth factor-dependent mechanism.

Journal of the American Heart Association

Volumn 2, Issue 1, 2013, Pages

  McGraw, Adam P ^a   Bagley, Jessamyn ^b   Chen, Wei Sheng ^b   Galayda, Carol ^b   Nickerson, Heather ^b   Armani, Andrea ^b   Caprio, Massimiliano ^b   Carmeliet, Peter ^b   Jaffe, Iris Z ^b  

^a TUFTS MEDICAL CENTER   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ALDOSTERONE; APOLIPOPROTEIN E; CCL5 PROTEIN, MOUSE; MINERALOCORTICOID ANTAGONIST; PLACENTA PROTEIN; PLACENTAL GROWTH FACTOR; RANTES;

ABDOMINAL AORTA; ANIMAL; AORTA DISEASE; ARTICLE; ATHEROSCLEROSIS; ATHEROSCLEROTIC PLAQUE; BLOOD FLOW; C57BL MOUSE; CELL STRAIN HEK293; CELL STRAIN U937; CHEMICALLY INDUCED DISORDER; DISEASE MODEL; DRUG EFFECT; GENETIC PREDISPOSITION; GENETICS; HUMAN; IMMUNOLOGY; INFLAMMATION; KNOCKOUT MOUSE; MALE; MECHANICAL STRESS; METABOLISM; MONOCYTE; MOUSE; PATHOLOGY; PATHOPHYSIOLOGY; PHENOTYPE; SIGNAL TRANSDUCTION; SMOOTH MUSCLE FIBER; T LYMPHOCYTE; TIME; VASCULAR SMOOTH MUSCLE;

ALDOSTERONE; ANIMALS; AORTA, ABDOMINAL; AORTIC DISEASES; APOLIPOPROTEINS E; ATHEROSCLEROSIS; CHEMOKINE CCL5; DISEASE MODELS, ANIMAL; GENETIC PREDISPOSITION TO DISEASE; HEK293 CELLS; HUMANS; INFLAMMATION; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MINERALOCORTICOID RECEPTOR ANTAGONISTS; MONOCYTES; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; PHENOTYPE; PLAQUE, ATHEROSCLEROTIC; PREGNANCY PROTEINS; REGIONAL BLOOD FLOW; SIGNAL TRANSDUCTION; STRESS, MECHANICAL; T-LYMPHOCYTES; TIME FACTORS; U937 CELLS;

EID: 84879499342     PISSN: None     EISSN: 20479980     Source Type: None    
DOI: 10.1161/JAHA.112.000018     Document Type: Article

References (0)