Inducible renal principal cell-specific mineralocorticoid receptor gene inactivation in mice

American Journal of Physiology - Renal Physiology

Volumn 300, Issue 3, 2011, Pages

  Ronzaud, Caroline ^a   Loffing, Johannes ^b   Gretz, Norbert ^c   Schütz, Günther ^a   Berger, Stefan ^a  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^b UNIVERSITY OF ZURICH   (Switzerland)

^c MEDICAL FACULTY MANNHEIM HEIDELBERG UNIVERSITY   (Germany)

Author keywords

AQP2; Tamoxifen

Indexed keywords

AQUAPORIN 2; CRE RECOMBINASE; DNA; HYBRID PROTEIN; MINERALOCORTICOID RECEPTOR; TAMOXIFEN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL SPECIFICITY; CONTROLLED STUDY; GENE EXPRESSION REGULATION; GENE INACTIVATION; IMMUNOHISTOCHEMISTRY; KIDNEY; MOUSE; NONHUMAN; PRIORITY JOURNAL; RECEPTOR GENE; SODIUM RESTRICTION; TRANSGENE; TRANSGENIC MOUSE;

EID: 79954567190     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00728.2009     Document Type: Article

References (12)

1. Bachmann S, Bostanjoglo M, Schmitt R, Ellison DH. Sodium transport-related proteins in the mammalian distal nephron - distribution, ontogeny and functional aspects. Anat Embryol 200: 447-468, 1999.
2. + metabolism. Proc Natl Acad Sci USA 95: 9424-9429, 1998.
3. Berger S, Wolfer DP, Selbach O, Alter H, Erdmann G, Reichardt HM, Chepkova AN, Welzl H, Haas HL, Lipp HP, Schutz G. Loss of the limbic mineralocorticoid receptor impairs behavioral plasticity. Proc Natl Acad Sci USA 103: 195-200, 2006.
4. Bonvalet JP. Regulation of sodium transport by steroid hormones. Kidney Int 65: S49-S56, 1998.
5. Erdmann G, Schutz G, Berger S. Inducible gene inactivation in neurons of the adult mouse forebrain. BMC Neurosci 8: 63, 2007.
6. Feil R, Wagner J, Metzger D, Chambon P. Regulation of Cre recom-binase activity by mutated estrogen receptor ligand-binding domains. Biochem Biophys Res Commun 237: 752-757, 1997.
7. Horster M. Embryonic epithelial membrane transporters. Am J Physiol Renal Physiol 279: F982-F996, 2000.
8. Loffing J, Kaissling B. Sodium and calcium transport pathways along the mammalian distal nephron: from rabbit to human. Am J Physiol Renal Physiol 284: F628-F643, 2003.
9. Meneton P. Comparative roles of the renal apical sodium transport systems in blood pressure control. J Am Soc Nephrol 11, Suppl 16: S135-S139, 2000.
10. Ronzaud C, Loffing J, Bleich M, Gretz N, Grone HJ, Schutz G, Berger S. Impairment of sodium balance in mice deficient in renal principal cell mineralocorticoid receptor. J Am Soc Nephrol 18: 1679-1687, 2007.
11. Schedl A, Grimes B, Montoliu L. YAC transfer by microinjection. Methods Mol Biol 54: 293-306, 1996.
12. Yamamoto T, Sasaki S, Fushimi K, Ishibashi K, Yaoita E, Kawasaki K, Fujinaka H, Marumo F, Kihara I. Expression of AQP family in rat kidneys during development and maturation. Am J Physiol Renal Physiol 272: F198-F204, 1997.