메뉴 건너뛰기




Volumn 7, Issue 4, 2013, Pages 496-507

Significance and strategies in developing delivery systems for bio-macromolecular drugs

Author keywords

bio macromolecular drugs; cell penetrating peptides; delivery systems

Indexed keywords


EID: 84890426175     PISSN: 20950179     EISSN: 20950187     Source Type: Journal    
DOI: 10.1007/s11705-013-1362-1     Document Type: Review
Times cited : (19)

References (77)
  • 1
    • 1642362625 scopus 로고    scopus 로고
    • Drug delivery systems: entering the mainstream
    • Allen T M, Cullis P R. Drug delivery systems: entering the mainstream. Science, 2004, 303(5665): 1818-1822.
    • (2004) Science , vol.303 , Issue.5665 , pp. 1818-1822
    • Allen, T.M.1    Cullis, P.R.2
  • 4
    • 0026926609 scopus 로고    scopus 로고
    • Conjugates of anticancer agents and polymers: Advantages of macromolecular therapeutics in vivo
    • Maeda H, Seymour L W, Miyamoto Y. Conjugates of anticancer agents and polymers: Advantages of macromolecular therapeutics in vivo. Bioconjugate Chemistry, 2002, 3(5): 351-362.
    • (2002) Bioconjugate Chemistry , vol.3 , Issue.5 , pp. 351-362
    • Maeda, H.1    Seymour, L.W.2    Miyamoto, Y.3
  • 5
    • 0028833556 scopus 로고
    • Macromolecular drug carrier systems in cancer chemotherapy: macromolecular prodrugs
    • Takakura Y, Hashida M. Macromolecular drug carrier systems in cancer chemotherapy: macromolecular prodrugs. Critical Reviews in Oncology/Hematology, 1995, 18(3): 207-231.
    • (1995) Critical Reviews in Oncology/Hematology , vol.18 , Issue.3 , pp. 207-231
    • Takakura, Y.1    Hashida, M.2
  • 9
    • 0029379702 scopus 로고
    • Targeting of drugs and drug carriers within the cardiovascular system
    • Torchilin V P. Targeting of drugs and drug carriers within the cardiovascular system. Advanced Drug Delivery Reviews, 1995, 17(1): 75-101.
    • (1995) Advanced Drug Delivery Reviews , vol.17 , Issue.1 , pp. 75-101
    • Torchilin, V.P.1
  • 10
  • 11
    • 0035284555 scopus 로고    scopus 로고
    • Sweet potato [beta]-amylase immobilized on chitosan beads and its application in the semi-continuous production of maltose
    • Noda T, Furuta S, Suda I. Sweet potato [beta]-amylase immobilized on chitosan beads and its application in the semi-continuous production of maltose. Carbohydrate Polymers, 2001, 44(3): 189-195.
    • (2001) Carbohydrate Polymers , vol.44 , Issue.3 , pp. 189-195
    • Noda, T.1    Furuta, S.2    Suda, I.3
  • 12
    • 0029098530 scopus 로고
    • Antibody-directed targeting of the vasculature of solid tumors
    • Thorpe P E, Burrows F J. Antibody-directed targeting of the vasculature of solid tumors. Breast Cancer Research and Treatment, 1995, 36(2): 237-251.
    • (1995) Breast Cancer Research and Treatment , vol.36 , Issue.2 , pp. 237-251
    • Thorpe, P.E.1    Burrows, F.J.2
  • 14
    • 0026792807 scopus 로고
    • A method for increasing the yield of properly folded recombinant fusion proteins: Single-chain immunotoxins from renaturation of bacterial inclusion bodies
    • Buchner J, Pastan I, Brinkmann U. A method for increasing the yield of properly folded recombinant fusion proteins: Single-chain immunotoxins from renaturation of bacterial inclusion bodies. Analytical Biochemistry, 1992, 205(2): 263-270.
    • (1992) Analytical Biochemistry , vol.205 , Issue.2 , pp. 263-270
    • Buchner, J.1    Pastan, I.2    Brinkmann, U.3
  • 16
    • 0029964835 scopus 로고    scopus 로고
    • A novel method for real time quantitative RT-PCR
    • Gibson U E, Heid C A, Williams P M. A novel method for real time quantitative RT-PCR. Genome Research, 1996, 6(10): 995-1001.
    • (1996) Genome Research , vol.6 , Issue.10 , pp. 995-1001
    • Gibson, U.E.1    Heid, C.A.2    Williams, P.M.3
  • 18
    • 0032897384 scopus 로고    scopus 로고
    • Antibody directed enzyme prodrug therapy (ADEPT): A review of the experimental and clinical considerations
    • Syrigos K N, Epenetos A A. Antibody directed enzyme prodrug therapy (ADEPT): A review of the experimental and clinical considerations. Anticancer Research, 1999, 19(1A): 605-613.
    • (1999) Anticancer Research , vol.19 , Issue.1 A , pp. 605-613
    • Syrigos, K.N.1    Epenetos, A.A.2
  • 19
    • 0023619243 scopus 로고
    • Antibody directed enzymes revive anti-cancer prodrugs concept
    • Bagshawe K D. Antibody directed enzymes revive anti-cancer prodrugs concept. British Journal of Cancer, 1987, 56(5): 531-532.
    • (1987) British Journal of Cancer , vol.56 , Issue.5 , pp. 531-532
    • Bagshawe, K.D.1
  • 21
    • 0003700389 scopus 로고    scopus 로고
    • Doxorubicin Hydrochloride, American Hospital Formulary Service, Bethesda, MD
    • Doxorubicin Hydrochloride. In: AHFS Drug Information, American Hospital Formulary Service, Bethesda, MD. 2001, 950-960.
    • (2001) AHFS Drug Information , pp. 950-960
  • 22
    • 0035858295 scopus 로고    scopus 로고
    • ATTEMPTS: A heparin/protamine-based prodrug approach for delivery of thrombolytic drugs
    • Liang J F, Park Y J, Song H, Li Y T, Yang V C. ATTEMPTS: A heparin/protamine-based prodrug approach for delivery of thrombolytic drugs. Journal of Controlled Release, 2001, 72(1-3): 145-156.
    • (2001) Journal of Controlled Release , vol.72 , Issue.1-3 , pp. 145-156
    • Liang, J.F.1    Park, Y.J.2    Song, H.3    Li, Y.T.4    Yang, V.C.5
  • 23
    • 0025840528 scopus 로고
    • 0 glycoprotein from peripheral nerve myelin into human M21 melanoma cells
    • 0 glycoprotein from peripheral nerve myelin into human M21 melanoma cells. Journal of Pharmaceutical Sciences, 1991, 80(11): 1020-1028.
    • (1991) Journal of Pharmaceutical Sciences , vol.80 , Issue.11 , pp. 1020-1028
    • Foldvari, M.1    Mezei, C.2    Mezei, M.3
  • 25
    • 0024445852 scopus 로고
    • Transfer of monoclonal antibodies into mammalian cells by electroporation
    • Chakrabarti R, Wylie D E, Schuster S M. Transfer of monoclonal antibodies into mammalian cells by electroporation. Journal of Biological Chemistry, 1989, 264(26): 15494-15500.
    • (1989) Journal of Biological Chemistry , vol.264 , Issue.26 , pp. 15494-15500
    • Chakrabarti, R.1    Wylie, D.E.2    Schuster, S.M.3
  • 26
    • 0025872046 scopus 로고
    • Peptides fused to the amino-terminal end of diphtheria toxin are translocated to the cytosol
    • Stenmark H, Moskaug J O, Madshus I H, Sandvig K, Olsnes S. Peptides fused to the amino-terminal end of diphtheria toxin are translocated to the cytosol. The Journal of Cell Biology, 1991, 113(5): 1025-1032.
    • (1991) The Journal of Cell Biology , vol.113 , Issue.5 , pp. 1025-1032
    • Stenmark, H.1    Moskaug, J.O.2    Madshus, I.H.3    Sandvig, K.4    Olsnes, S.5
  • 27
    • 0025064922 scopus 로고
    • Receptor-mediated endocytosis of macromolecular conjugates in selective drug delivery
    • Basu S K. Receptor-mediated endocytosis of macromolecular conjugates in selective drug delivery. Biochemical Pharmacology, 1990, 40(9): 1941-1946.
    • (1990) Biochemical Pharmacology , vol.40 , Issue.9 , pp. 1941-1946
    • Basu, S.K.1
  • 28
    • 0024282306 scopus 로고
    • Evidence for targeted gene delivery to Hep G2 hepatoma cells in vitro
    • Wu G Y, Wu C H. Evidence for targeted gene delivery to Hep G2 hepatoma cells in vitro. Biochemistry, 1988, 27(3): 887-892.
    • (1988) Biochemistry , vol.27 , Issue.3 , pp. 887-892
    • Wu, G.Y.1    Wu, C.H.2
  • 30
    • 0033791994 scopus 로고    scopus 로고
    • Designer genes: Recombinant antibody fragments for biological imaging
    • Wu A M, Yazaki P J. Designer genes: Recombinant antibody fragments for biological imaging. The Quarterly Journal of Nuclear Medicine, 2000, 44(3): 268-283.
    • (2000) The Quarterly Journal of Nuclear Medicine , vol.44 , Issue.3 , pp. 268-283
    • Wu, A.M.1    Yazaki, P.J.2
  • 32
    • 0026739369 scopus 로고
    • Micropharmacology of monoclonal antibodies in solid tumors: direct experimental evidence for a binding site barrier
    • Juweid M, Neumann R, Paik C, Perez-Bacete MJ, Sato J, van Osdol W, Weinstein J N. Micropharmacology of monoclonal antibodies in solid tumors: direct experimental evidence for a binding site barrier. Cancer Research, 1992, 52(19): 5144-5153.
    • (1992) Cancer Research , vol.52 , Issue.19 , pp. 5144-5153
    • Juweid, M.1    Neumann, R.2    Paik, C.3    Perez-Bacete, M.J.4    Sato, J.5    van Osdol, W.6    Weinstein, J.N.7
  • 34
    • 0024232289 scopus 로고
    • Mechanisms of heterogeneous distribution of monoclonal antibodies and other macromolecules in tumors: Significance of elevated interstitial pressure
    • Jain R K, Baxter L T. Mechanisms of heterogeneous distribution of monoclonal antibodies and other macromolecules in tumors: Significance of elevated interstitial pressure. Cancer Research, 1988, 48: 7022-7032.
    • (1988) Cancer Research , vol.48 , pp. 7022-7032
    • Jain, R.K.1    Baxter, L.T.2
  • 36
    • 0006052482 scopus 로고
    • A covalent linkage between daunorubicin and proteins that is stable in serum and reversible by lysosomal hydrolases, as required for a lysosomotropic drug-carrier conjugate: In vitro and in vivo studies
    • Trouet A, Masquelier M, Baurain R, Campeneere D D. A covalent linkage between daunorubicin and proteins that is stable in serum and reversible by lysosomal hydrolases, as required for a lysosomotropic drug-carrier conjugate: In vitro and in vivo studies. Proceedings of the National Academy of Sciences of the United States of America, 1982, 79(2): 626-629.
    • (1982) Proceedings of the National Academy of Sciences of the United States of America , vol.79 , Issue.2 , pp. 626-629
    • Trouet, A.1    Masquelier, M.2    Baurain, R.3    Campeneere, D.D.4
  • 38
    • 0026073686 scopus 로고
    • Inhibition of human renal cancer by monoclonal antibody-linked methotrexate in an ascites tumor model
    • Singh M, Ghose T, Kralovec J, Blair A H, Belitsky P. Inhibition of human renal cancer by monoclonal antibody-linked methotrexate in an ascites tumor model. Cancer Immunology, Immunotherapy, 1991, 32(5): 331-334.
    • (1991) Cancer Immunology, Immunotherapy , vol.32 , Issue.5 , pp. 331-334
    • Singh, M.1    Ghose, T.2    Kralovec, J.3    Blair, A.H.4    Belitsky, P.5
  • 41
    • 0023619243 scopus 로고
    • Antibody directed enzymes revive anti-cancer prodrugs concept
    • Bagshawe K D. Antibody directed enzymes revive anti-cancer prodrugs concept. British Journal of Cancer, 1987, 56(5): 531-532.
    • (1987) British Journal of Cancer , vol.56 , Issue.5 , pp. 531-532
    • Bagshawe, K.D.1
  • 42
    • 0026757191 scopus 로고
    • Drug-polymer conjugates: Potential for improved chemotherapy
    • Duncan R. Drug-polymer conjugates: Potential for improved chemotherapy. Drug Research, 1992, 3(3): 175-210.
    • (1992) Drug Research , vol.3 , Issue.3 , pp. 175-210
    • Duncan, R.1
  • 43
    • 0026926609 scopus 로고    scopus 로고
    • Conjugates of anticancer agents and polymers: Advantages of macromolecular therapeutics in vivo
    • Maeda H, Seymour L W, Miyamoto Y. Conjugates of anticancer agents and polymers: Advantages of macromolecular therapeutics in vivo. Bioconjugate Chemistry, 1992, 3(5): 351-362.
    • (1992) Bioconjugate Chemistry , vol.3 , Issue.5 , pp. 351-362
    • Maeda, H.1    Seymour, L.W.2    Miyamoto, Y.3
  • 44
    • 0034000453 scopus 로고    scopus 로고
    • Tumor vascular permeability and the EPR effect in macromolecular therapeutics: A review
    • Maeda H, Wu J, Sawa T, Matsumura Y, Hori K. Tumor vascular permeability and the EPR effect in macromolecular therapeutics: A review. Journal of Controlled Release, 2000, 65(1-2): 271-284.
    • (2000) Journal of Controlled Release , vol.65 , Issue.1-2 , pp. 271-284
    • Maeda, H.1    Wu, J.2    Sawa, T.3    Matsumura, Y.4    Hori, K.5
  • 45
    • 0026694788 scopus 로고
    • Passive tumor targeting of soluble macromolecules and drug conjugates
    • Seymour L W. Passive tumor targeting of soluble macromolecules and drug conjugates. Critical Reviews in Therapeutic Drug Carrier Systems, 1992, 9(2): 135-187.
    • (1992) Critical Reviews in Therapeutic Drug Carrier Systems , vol.9 , Issue.2 , pp. 135-187
    • Seymour, L.W.1
  • 46
    • 0035575846 scopus 로고    scopus 로고
    • Targeting Stealth liposomes in a murine model of human small cell lung cancer
    • Moreira J N, Gaspar R, Allen T M. Targeting Stealth liposomes in a murine model of human small cell lung cancer. Biochimica et Biophysica Acta, 2001, 1515(2): 167-176.
    • (2001) Biochimica Et Biophysica Acta , vol.1515 , Issue.2 , pp. 167-176
    • Moreira, J.N.1    Gaspar, R.2    Allen, T.M.3
  • 48
    • 0016812692 scopus 로고
    • Mechanism by which antibodies inhibit hapten-malate dehydrogenase conjugates. An enzyme immunoassay for morphine
    • Rowley G L, Rubenstein K E, Huisjen J, Ullman E F. Mechanism by which antibodies inhibit hapten-malate dehydrogenase conjugates. An enzyme immunoassay for morphine. Journal of Biological Chemistry, 1975, 250(10): 3759-3766.
    • (1975) Journal of Biological Chemistry , vol.250 , Issue.10 , pp. 3759-3766
    • Rowley, G.L.1    Rubenstein, K.E.2    Huisjen, J.3    Ullman, E.F.4
  • 49
    • 0024209811 scopus 로고
    • Autonomous functional domains of chemically synthesized human immunodeficiency virus tat transactivator protein
    • Green M, Loewenstein P M. Autonomous functional domains of chemically synthesized human immunodeficiency virus tat transactivator protein. Cell, 1988, 55(6): 1179-1188.
    • (1988) Cell , vol.55 , Issue.6 , pp. 1179-1188
    • Green, M.1    Loewenstein, P.M.2
  • 50
    • 0024262589 scopus 로고
    • Cellular uptake of the tat protein from human immunodeficiency virus
    • Frankel A D, Pabo C O. Cellular uptake of the tat protein from human immunodeficiency virus. Cell, 1988, 55(6): 1189-1193.
    • (1988) Cell , vol.55 , Issue.6 , pp. 1189-1193
    • Frankel, A.D.1    Pabo, C.O.2
  • 51
    • 32544443657 scopus 로고    scopus 로고
    • Selective destruction of glioblastoma cells by interference with the activity or expression of ATF5
    • Angelastro J M, Canoll P D, Kuo J, Weicker M, Costa A, Bruce J N, Greene L A. Selective destruction of glioblastoma cells by interference with the activity or expression of ATF5. Oncogene, 2006, 25(6): 907-916.
    • (2006) Oncogene , vol.25 , Issue.6 , pp. 907-916
    • Angelastro, J.M.1    Canoll, P.D.2    Kuo, J.3    Weicker, M.4    Costa, A.5    Bruce, J.N.6    Greene, L.A.7
  • 52
    • 0028239908 scopus 로고
    • The third helix of the Antennapedia homeodomain translocates through biological membranes
    • Derossi D, Joliot A H, Chassaing G, Prochiantz A. The third helix of the Antennapedia homeodomain translocates through biological membranes. Journal of Biological Chemistry, 1994, 269(14): 10444-10450.
    • (1994) Journal of Biological Chemistry , vol.269 , Issue.14 , pp. 10444-10450
    • Derossi, D.1    Joliot, A.H.2    Chassaing, G.3    Prochiantz, A.4
  • 53
    • 0031471203 scopus 로고    scopus 로고
    • Intercellular trafficking and protein delivery by a herpesvirus structural protein
    • Elliott G, O'Hare P. Intercellular trafficking and protein delivery by a herpesvirus structural protein. Cell, 1997, 88(2): 223-233.
    • (1997) Cell , vol.88 , Issue.2 , pp. 223-233
    • Elliott, G.1    O'Hare, P.2
  • 54
    • 0037172801 scopus 로고    scopus 로고
    • Translocation of branched-chain arginine peptides through cell membranes: Flexibility in the spatial disposition of positive charges in membranepermeable peptides
    • Futaki S, Nakase I, Suzuki T, Youjun Z, Sugiura Y. Translocation of branched-chain arginine peptides through cell membranes: Flexibility in the spatial disposition of positive charges in membranepermeable peptides. Biochemistry, 2002, 41(25): 7925-7930.
    • (2002) Biochemistry , vol.41 , Issue.25 , pp. 7925-7930
    • Futaki, S.1    Nakase, I.2    Suzuki, T.3    Youjun, Z.4    Sugiura, Y.5
  • 55
    • 24644512176 scopus 로고    scopus 로고
    • Nontoxic membrane translocation peptide from protamine, low molecular weight protamine (LMWP), for enhanced intracellular low protein delivery: In vitro and in vivo study
    • Park Y J, Chang L C, Liang J F, Moon C, Chung C P, Yang V C. Nontoxic membrane translocation peptide from protamine, low molecular weight protamine (LMWP), for enhanced intracellular low protein delivery: In vitro and in vivo study. FASEB Journal, 2005, 19(11): 1555-1557.
    • (2005) FASEB Journal , vol.19 , Issue.11 , pp. 1555-1557
    • Park, Y.J.1    Chang, L.C.2    Liang, J.F.3    Moon, C.4    Chung, C.P.5    Yang, V.C.6
  • 56
    • 0011967676 scopus 로고    scopus 로고
    • Low molecular weight protamine (LMWP) as nontoxic heparin/LMWH antidote (I): Preparation and characterization
    • Chang L C, Lee H F, Yang Z Q, Yang V C. Low molecular weight protamine (LMWP) as nontoxic heparin/LMWH antidote (I): Preparation and characterization. AAPS PharmSci, 2001, 3(2): E17.
    • (2001) AAPS PharmSci , vol.3 , Issue.2
    • Chang, L.C.1    Lee, H.F.2    Yang, Z.Q.3    Yang, V.C.4
  • 57
    • 0035783151 scopus 로고    scopus 로고
    • Low molecular weight protamine (LMWP) as nontoxic heparin/LMWH antidote (II): In vitro evaluation of efficacy and toxicity
    • Chang L C, Liang J F, Lee H F, Lee LM, Yang V C. Low molecular weight protamine (LMWP) as nontoxic heparin/LMWH antidote (II): In vitro evaluation of efficacy and toxicity. AAPS PharmSci, 2001, 3(2): E18.
    • (2001) AAPS PharmSci , vol.3 , Issue.2
    • Chang, L.C.1    Liang, J.F.2    Lee, H.F.3    Lee, L.M.4    Yang, V.C.5
  • 58
    • 0035783265 scopus 로고    scopus 로고
    • Low molecular weight protamine as nontoxic heparin/LMWH antidote (III): Preliminary in vivo evaluation of efficacy and toxicity using a canine model
    • Lee L M, Chang L C, Wrobleski S, Wakefield TW, Yang V C. Low molecular weight protamine as nontoxic heparin/LMWH antidote (III): Preliminary in vivo evaluation of efficacy and toxicity using a canine model. AAPS PharmSci, 2001, 3(2): E19.
    • (2001) AAPS PharmSci , vol.3 , Issue.2
    • Lee, L.M.1    Chang, L.C.2    Wrobleski, S.3    Wakefield, T.W.4    Yang, V.C.5
  • 59
    • 0034141430 scopus 로고    scopus 로고
    • In vivo protein transduction: intracellular delivery of biologically active proteins, compounds and DNA
    • Schwarze S R, Dowdy S F. In vivo protein transduction: intracellular delivery of biologically active proteins, compounds and DNA. Trends in Pharmacological Sciences, 2000, 21(2): 45-48.
    • (2000) Trends in Pharmacological Sciences , vol.21 , Issue.2 , pp. 45-48
    • Schwarze, S.R.1    Dowdy, S.F.2
  • 61
  • 62
    • 0033106072 scopus 로고    scopus 로고
    • High-efficiency intracellular magnetic labeling with novel superparamagnetic-Tat peptide conjugates
    • Josephson L, Tung C H, Moore A, Weissleder R. High-efficiency intracellular magnetic labeling with novel superparamagnetic-Tat peptide conjugates. Bioconjugate Chemistry, 1999, 10(2): 186-191.
    • (1999) Bioconjugate Chemistry , vol.10 , Issue.2 , pp. 186-191
    • Josephson, L.1    Tung, C.H.2    Moore, A.3    Weissleder, R.4
  • 63
    • 0033520487 scopus 로고    scopus 로고
    • In vivo protein transduction: delivery of a biologically active protein into the mouse
    • Schwarze S R, Ho A, Vocero-Akbani A, Dowdy S F. In vivo protein transduction: delivery of a biologically active protein into the mouse. Science, 1999, 285(5433): 1569-1572.
    • (1999) Science , vol.285 , Issue.5433 , pp. 1569-1572
    • Schwarze, S.R.1    Ho, A.2    Vocero-Akbani, A.3    Dowdy, S.F.4
  • 67
    • 0035279632 scopus 로고    scopus 로고
    • Reduced reactivity towards anti-protamine antibodies of a low molecular weight protamine analogue
    • Tsui B, Singh V K, Liang J F, Yang V C. Reduced reactivity towards anti-protamine antibodies of a low molecular weight protamine analogue. Thrombosis Research, 2001, 101(5): 417-420.
    • (2001) Thrombosis Research , vol.101 , Issue.5 , pp. 417-420
    • Tsui, B.1    Singh, V.K.2    Liang, J.F.3    Yang, V.C.4
  • 68
    • 0037225827 scopus 로고    scopus 로고
    • A less toxic heparin antagonist-low molecular weight protamine
    • Liang J F, Zhen L, Chang L C, Yang V C. A less toxic heparin antagonist-low molecular weight protamine. Biochemistry (Moscow), 2003, 68(1): 116-120.
    • (2003) Biochemistry (Moscow) , vol.68 , Issue.1 , pp. 116-120
    • Liang, J.F.1    Zhen, L.2    Chang, L.C.3    Yang, V.C.4
  • 69
    • 70349871400 scopus 로고    scopus 로고
    • Substantiating in vivo magnetic brain tumor targeting of cationic iron oxide nanocarriers via adsorptive surface masking
    • Chertok B, David A E, Moffat B A, Yang V C. Substantiating in vivo magnetic brain tumor targeting of cationic iron oxide nanocarriers via adsorptive surface masking. Biomaterials, 2009, 30(35): 6780-6787.
    • (2009) Biomaterials , vol.30 , Issue.35 , pp. 6780-6787
    • Chertok, B.1    David, A.E.2    Moffat, B.A.3    Yang, V.C.4
  • 70
    • 77349107946 scopus 로고    scopus 로고
    • Size-tunable synthesis of stable superparamagnetic iron oxide nanoparticles for potential biomedical applications
    • Yu F, Yang V C. Size-tunable synthesis of stable superparamagnetic iron oxide nanoparticles for potential biomedical applications. Journal of Biomedical Materials Research Part A, 2010, 92(4): 1468-1475.
    • (2010) Journal of Biomedical Materials Research Part A , vol.92 , Issue.4 , pp. 1468-1475
    • Yu, F.1    Yang, V.C.2
  • 71
    • 77953081585 scopus 로고    scopus 로고
    • The magnetophoretic mobility and superpara-magnetism of core-shell iron oxide nanoparticles with dual targeting and imaging functionality
    • Yu F, Zhang L, Huang Y, Sun K, David A E, Yang V C. The magnetophoretic mobility and superpara-magnetism of core-shell iron oxide nanoparticles with dual targeting and imaging functionality. Biomaterials, 2010, 31(22): 5842-5848.
    • (2010) Biomaterials , vol.31 , Issue.22 , pp. 5842-5848
    • Yu, F.1    Zhang, L.2    Huang, Y.3    Sun, K.4    David, A.E.5    Yang, V.C.6
  • 73
    • 80054708438 scopus 로고    scopus 로고
    • Brain tumor targeting of magnetic nanoparticles for potential drug delivery: effect of administration route and magnetic field topography
    • Chertok B, David A E, Yang V C. Brain tumor targeting of magnetic nanoparticles for potential drug delivery: effect of administration route and magnetic field topography. Journal of Controlled Release, 2011, 155(3): 393-399.
    • (2011) Journal of Controlled Release , vol.155 , Issue.3 , pp. 393-399
    • Chertok, B.1    David, A.E.2    Yang, V.C.3
  • 74
    • 77953651162 scopus 로고    scopus 로고
    • Polyethyleneimine-modified iron oxide nanoparticles for brain tumor drug delivery using magnetic targeting and intra-carotid administration
    • Chertok B, David A E, Yang V C. Polyethyleneimine-modified iron oxide nanoparticles for brain tumor drug delivery using magnetic targeting and intra-carotid administration. Biomaterials, 2010, 31(24): 6317-6324.
    • (2010) Biomaterials , vol.31 , Issue.24 , pp. 6317-6324
    • Chertok, B.1    David, A.E.2    Yang, V.C.3
  • 75
    • 70349871400 scopus 로고    scopus 로고
    • Substantiating in vivo magnetic brain tumor targeting of cationic iron oxide nanocarriers via adsorptive surface masking
    • Chertok B, David A E, Moffat B A, Yang V C. Substantiating in vivo magnetic brain tumor targeting of cationic iron oxide nanocarriers via adsorptive surface masking. Biomaterials, 2009, 30(35): 6780-6787.
    • (2009) Biomaterials , vol.30 , Issue.35 , pp. 6780-6787
    • Chertok, B.1    David, A.E.2    Moffat, B.A.3    Yang, V.C.4
  • 76
    • 77950580053 scopus 로고    scopus 로고
    • Comparison of electron spin resonance spectroscopy and inductively-coupled plasma optical emission spectroscopy for biodistribution analysis of iron-oxide nanoparticles
    • Chertok B, Cole A J, David A E, Yang V C. Comparison of electron spin resonance spectroscopy and inductively-coupled plasma optical emission spectroscopy for biodistribution analysis of iron-oxide nanoparticles. Molecular Pharmaceutics, 2010, 7(2): 375-385.
    • (2010) Molecular Pharmaceutics , vol.7 , Issue.2 , pp. 375-385
    • Chertok, B.1    Cole, A.J.2    David, A.E.3    Yang, V.C.4
  • 77
    • 79959874155 scopus 로고    scopus 로고
    • Magnetically-enabled and MRmonitored selective brain tumor protein delivery in rats via magnetic nanocarriers
    • Chertok B, David A E, Yang V C. Magnetically-enabled and MRmonitored selective brain tumor protein delivery in rats via magnetic nanocarriers. Biomaterials, 2011, 32(26): 6245-6253.
    • (2011) Biomaterials , vol.32 , Issue.26 , pp. 6245-6253
    • Chertok, B.1    David, A.E.2    Yang, V.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.