Screening of small molecules affecting mammalian P-body assembly uncovers links with diverse intracellular processes and organelle physiology

RNA Biology

Volumn 10, Issue 11, 2013, Pages 1661-1669

  Martińez, Javier P ^a   Peŕez Vilaró, Gemma ^a   Muthukumar, Yazh ^b   Scheller, Nicoletta ^a   Hirsch, Tatjana ^b   Diestel, Randi ^b   Steinmetz, Heinrich ^b   Jansen, Rolf ^b   Frank, Ronald ^b   Sasse, Florenz ^b   Meyerhans, Andreas ^a,c   Diéz, Juana ^a  

^a UNIVERSITAT POMPEU FABRA   (Spain)

^b HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

^c INSTITUCIÓ CATALANA DE RECERCA I ESTUDIS AVANÇATS ICREA   (Spain)

Author keywords

EIF2 ; Gephyronic acid A; Inhibitors; Myxobacterial metabolites; P body assembly; Processing bodies; Stress granules

Indexed keywords

ANTIFUNGAL AGENT; ARCHAZOLID A; AURACHIN D; CAROLACTON; CEREBROSID 751; CROCACIN C; CROCAPEPTIN A; CRUENTAREN A; DISORAZOL B1; GEPHYRONIC ACID A; INITIATION FACTOR 2ALPHA; JERANGOLID A; KULKENON; LEUPYRRIN A1; LIPID; MALTEPOLID B; METHYL CHIVOSAZOL; MYXALAMID B; PELLASOREN; PROTEIN INHIBITOR; PROTEIN SYNTHESIS INHIBITOR; SORAPHEN B1; SORAPHEN B2 ALPHA; SORAPHEN E1; SORAPHEN F; SPIRANGIEN B; THUGGACIN B; TUBULYSIN B; UNCLASSIFIED DRUG; UNINDEXED DRUG; VIOPROLID D;

ARTICLE; BACTERIAL STRAIN; CELL ASSAY; CELL FUNCTION; CELL GRANULE; CELL ORGANELLE; CELL STRESS; CELL VIABILITY; CONTROLLED STUDY; DRUG EFFECT; DRUG SCREENING; FEMALE; HUMAN; HUMAN CELL; INTRACELLULAR MEMBRANE; LIPID METABOLISM; MAMMAL; MOLECULE; MYXOCOCCALES; P BODY; PROTEIN ASSEMBLY; PROTEIN PHOSPHORYLATION;

EIF2Α; GEPHYRONIC ACID A; INHIBITORS; MYXOBACTERIAL METABOLITES; P-BODY ASSEMBLY; PROCESSING BODIES; STRESS GRANULES;

CELL LINE, TUMOR; CYCLOHEXIMIDE; CYTOPLASMIC GRANULES; DRUG DISCOVERY; EUKARYOTIC INITIATION FACTOR-2; FATTY ACIDS, MONOUNSATURATED; HELA CELLS; HUMANS; LIPID METABOLISM; MYXOCOCCALES; PHOSPHORYLATION; PUROMYCIN; RIBONUCLEOPROTEINS, SMALL CYTOPLASMIC; RNA STABILITY; SMALL MOLECULE LIBRARIES;

EID: 84890343815     PISSN: 15476286     EISSN: 15558584     Source Type: Journal    
DOI: 10.4161/rna.26851     Document Type: Article

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