Uptake, p53 pathway activation, and cytotoxic responses for Co(II) and Ni(II) in human lung cells: Implications for carcinogenicity

Toxicological Sciences

Volumn 136, Issue 2, 2013, Pages 467-477

  Green, Samantha E ^a   Luczak, Michal W ^a,b   Morse, Jessica L ^a   DeLoughery, Zachary ^a   Zhitkovich, Anatoly ^a  

^a BROWN UNIVERSITY   (United States)

^b POZNAN UNIVERSITY OF MEDICAL SCIENCES   (Poland)

Author keywords

Apoptosis; Cancer; Cobalt; Nickel; Toxicity; TP53

Indexed keywords

COBALT; NICKEL; PROTEIN MDMX; PROTEIN P53;

APOPTOSIS; ARTICLE; CARCINOGENICITY; CELL ACTIVATION; CELL DEATH; CELL SURVIVAL; CYTOTOXICITY; DNA REPLICATION; DOWN REGULATION; DRUG UPTAKE; EPIGENETICS; EPITHELIUM CELL; GENE EXPRESSION; HUMAN; LUNG ALVEOLUS CELL; LUNG FIBROBLAST; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; SUPPRESSOR CELL;

APOPTOSIS.; CANCER; COBALT; NICKEL; TOXICITY; TP53;

BASE SEQUENCE; CARCINOGENS; CELL LINE; COBALT; DNA PRIMERS; HUMANS; LUNG; NICKEL; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84890339863     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kft214     Document Type: Article

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