Ni(II) specifically cleaves the C-terminal tail of the major variant of histone H2A and forms an oxidative damage-mediating complex with the cleaved- off octapeptide

Chemical Research in Toxicology

Volumn 13, Issue 7, 2000, Pages 616-624

  Bal, Wojciech ^a,b,d   Liang, Rongti ^a   Lukszo, Jan ^c   Lee, Sang Han ^a,e   Dizdaroglu, Miral ^d   Kasprzak, Kazimierz S ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

^c NATIONAL INSTITUTE OF STANDARDS AND TECHNOLOGY   (United States)

^d UNIVERSITY OF WROC AW   (Poland)

^e Soonchunhyang University College of Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

HISTONE H2A; NICKEL; OCTAPEPTIDE;

ARTICLE; BINDING AFFINITY; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CARCINOGENESIS; DNA STRAND BREAKAGE; GENOTOXICITY; GEOMETRY; HYDROLYSIS; MATHEMATICAL MODEL; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PROTEIN DEGRADATION;

AMINO ACID SEQUENCE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DNA; DNA DAMAGE; HISTONES; HYDROGEN PEROXIDE; HYDROLYSIS; MOLECULAR SEQUENCE DATA; NICKEL; OLIGOPEPTIDES; OXIDATION-REDUCTION; OXIDATIVE STRESS;

EID: 0033914932     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx000044l     Document Type: Article

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