-
1
-
-
77950948813
-
Evading tumor evasion: Current concepts and perspectives of anti-angiogenic cancer therapy
-
Abdollahi, A., and Folkman, J. (2010). Evading tumor evasion: current concepts and perspectives of anti-angiogenic cancer therapy. Drug Resist. Updat. 13, 16-28.
-
(2010)
Drug Resist. Updat.
, vol.13
, pp. 16-28
-
-
Abdollahi, A.1
Folkman, J.2
-
2
-
-
70349446443
-
In vivo analysis of biocompatibility and vascularization of the synthetic bone grafting substitute nano bone
-
Abshagen, K., Schrodi, I., Gerber, T., et al. (2009). In vivo analysis of biocompatibility and vascularization of the synthetic bone grafting substitute Nano Bone. J. Biomed. Mater. Res. A 91, 557-566.
-
(2009)
J. Biomed. Mater. Res. A
, vol.91
, pp. 557-566
-
-
Abshagen, K.1
Schrodi, I.2
Gerber, T.3
-
3
-
-
75149120225
-
E2F1 inmelanoma progression and metastasis
-
Alla, V., Engelmann, D., Niemetz, A., et al. (2010). E2F1 inmelanoma progression and metastasis. J. Natl Cancer Inst. 102, 127-133.
-
(2010)
J. Natl Cancer Inst.
, vol.102
, pp. 127-133
-
-
Alla, V.1
Engelmann, D.2
Niemetz, A.3
-
4
-
-
84865344231
-
E2F1 confers anticancer drug resistance by targeting ABC transporter family members and Bcl-2 via the p73/DNp73-miR-205 circuitry
-
Alla, V., Kowtharapu, B.S., Engelmann, D., et al. (2012). E2F1 confers anticancer drug resistance by targeting ABC transporter family members and Bcl-2 via the p73/DNp73-miR-205 circuitry. Cell Cycle 11, 3067-3078.
-
(2012)
Cell Cycle
, vol.11
, pp. 3067-3078
-
-
Alla, V.1
Kowtharapu, B.S.2
Engelmann, D.3
-
5
-
-
0028355888
-
PDGF-BB modulates endothelial proliferation and angiogenesis in vitro via PDGF beta-receptors
-
Battegay, E.J., Rupp, J., Iruela-Arispe, L., et al. (1994). PDGF-BB modulates endothelial proliferation and angiogenesis in vitro via PDGF beta-receptors. J. Cell Biol. 125, 917-928.
-
(1994)
J. Cell Biol.
, vol.125
, pp. 917-928
-
-
Battegay, E.J.1
Rupp, J.2
Iruela-Arispe, L.3
-
6
-
-
47949099628
-
Modes of resistance to anti-angiogenic therapy
-
Bergers, G., and Hanahan, D. (2008). Modes of resistance to anti-angiogenic therapy. Nat. Rev. Cancer 8, 592-603.
-
(2008)
Nat. Rev. Cancer
, vol.8
, pp. 592-603
-
-
Bergers, G.1
Hanahan, D.2
-
7
-
-
72449178334
-
Division and apoptosis of E2f-deficient retinal progenitors
-
Chen, D., Pacal, M., Wenzel, P., et al. (2009a). Division and apoptosis of E2f-deficient retinal progenitors. Nature 462, 925-929.
-
(2009)
Nature
, vol.462
, pp. 925-929
-
-
Chen, D.1
Pacal, M.2
Wenzel, P.3
-
8
-
-
70350518233
-
Emerging roles of E2Fs in cancer: An exit from cell cycle control
-
Chen, H.Z., Tsai, S.Y., and Leone, G. (2009b). Emerging roles of E2Fs in cancer: an exit from cell cycle control. Nat. Rev. Cancer 9, 785-797.
-
(2009)
Nat. Rev. Cancer
, vol.9
, pp. 785-797
-
-
Chen, H.Z.1
Tsai, S.Y.2
Leone, G.3
-
9
-
-
73949133917
-
Vascular endothelial growth factor-C (VEGF-C) promotes angiogenesis by induction of COX-2 in leukemic cells via the VEGF-R3/JNK/AP-1 pathway
-
Chien, M.H., Ku, C.C., Johansson, G., et al. (2009). Vascular endothelial growth factor-C (VEGF-C) promotes angiogenesis by induction of COX-2 in leukemic cells via the VEGF-R3/JNK/AP-1 pathway. Carcinogenesis 30, 2005-2013.
-
(2009)
Carcinogenesis
, vol.30
, pp. 2005-2013
-
-
Chien, M.H.1
Ku, C.C.2
Johansson, G.3
-
10
-
-
77950402591
-
Co-expression of PDGF-B and VEGFR-3 strongly correlates with lymph node metastasis and poor survival in non-small-cell lung cancer
-
Donnem, T., Al-Saad, S., Al-Shibli, K., et al. (2010). Co-expression of PDGF-B and VEGFR-3 strongly correlates with lymph node metastasis and poor survival in non-small-cell lung cancer. Ann. Oncol. 21, 223-231.
-
(2010)
Ann. Oncol.
, vol.21
, pp. 223-231
-
-
Donnem, T.1
Al-Saad, S.2
Al-Shibli, K.3
-
11
-
-
77957931294
-
Translating DNA damage into cancer cell death-Aroadmap for E2F1 apoptotic signalling and opportunities fornewdrug combinations to overcome chemoresistance
-
Engelmann, D., and Putzer, B.M. (2010). Translating DNA damage into cancer cell death-Aroadmap for E2F1 apoptotic signalling and opportunities fornewdrug combinations to overcome chemoresistance. Drug Resist. Updat. 13, 119-131.
-
(2010)
Drug Resist. Updat.
, vol.13
, pp. 119-131
-
-
Engelmann, D.1
Putzer, B.M.2
-
12
-
-
84856557109
-
The dark side of E2F1: In transit beyond apoptosis
-
Engelmann, D., and Putzer, B.M. (2012). The dark side of E2F1: in transit beyond apoptosis. Cancer Res. 72, 571-575.
-
(2012)
Cancer Res.
, vol.72
, pp. 571-575
-
-
Engelmann, D.1
Putzer, B.M.2
-
13
-
-
77949529981
-
Functional interplay between E2F1 and chemotherapeutic drugs defines immediate E2F1 target genes crucial for cancer cell death
-
Engelmann, D., Knoll, S., Ewerth, D., et al. (2010). Functional interplay between E2F1 and chemotherapeutic drugs defines immediate E2F1 target genes crucial for cancer cell death. Cell. Mol. Life Sci. 67, 931-948.
-
(2010)
Cell. Mol. Life Sci.
, vol.67
, pp. 931-948
-
-
Engelmann, D.1
Knoll, S.2
Ewerth, D.3
-
14
-
-
75649083174
-
Inflammation induces lymphangiogenesis through up-regulation of VEGFR-3 mediated by NF-kappaB and Prox1
-
Flister, M.J., Wilber, A., Hall, K.L., et al. (2010). Inflammation induces lymphangiogenesis through up-regulation of VEGFR-3 mediated by NF-kappaB and Prox1. Blood 115, 418-429.
-
(2010)
Blood
, vol.115
, pp. 418-429
-
-
Flister, M.J.1
Wilber, A.2
Hall, K.L.3
-
15
-
-
70349791957
-
The execution of the transcriptional axis mutant p53, E2F1 and ID4 promotes tumor neo-angiogenesis
-
Fontemaggi, G., Dell'Orso, S., Trisciuoglio, D., et al. (2009). The execution of the transcriptional axis mutant p53, E2F1 and ID4 promotes tumor neo-angiogenesis. Nat. Struct. Mol. Biol. 16, 1086-1093.
-
(2009)
Nat. Struct. Mol. Biol.
, vol.16
, pp. 1086-1093
-
-
Fontemaggi, G.1
Dell'orso, S.2
Trisciuoglio, D.3
-
16
-
-
0042266787
-
Engineering the response to vascular injury: Divergent effects of deregulated E2F1 expression on vascular smooth muscle cells and endothelial cells result in endothelial recovery and inhibition of neointimal growth
-
Goukassian, D.A., Kishore, R., Krasinski, K., et al. (2003). Engineering the response to vascular injury: divergent effects of deregulated E2F1 expression on vascular smooth muscle cells and endothelial cells result in endothelial recovery and inhibition of neointimal growth. Circ. Res. 93, 162-169.
-
(2003)
Circ. Res.
, vol.93
, pp. 162-169
-
-
Goukassian, D.A.1
Kishore, R.2
Krasinski, K.3
-
17
-
-
0344837389
-
Platelet-derived growth factor-B enhances glioma angiogenesis by stimulating vascular endothelial growth factor expression in tumor endothelia and by promoting pericyte recruitment
-
Guo, P., Hu, B., Gu, W., et al. (2003). Platelet-derived growth factor-B enhances glioma angiogenesis by stimulating vascular endothelial growth factor expression in tumor endothelia and by promoting pericyte recruitment. Am. J. Pathol. 162, 1083-1093.
-
(2003)
Am. J. Pathol.
, vol.162
, pp. 1083-1093
-
-
Guo, P.1
Hu, B.2
Gu, W.3
-
18
-
-
0344394363
-
E2F1 expression is related with the poor survival of lymph node-positive breast cancer patients treated with fluorouracil, doxorubicin and cyclophosphamide
-
Han, S., Park, K., Bae, B.N., et al. (2003). E2F1 expression is related with the poor survival of lymph node-positive breast cancer patients treated with fluorouracil, doxorubicin and cyclophosphamide. Breast Cancer Res. Treat. 82, 11-16.
-
(2003)
Breast Cancer Res. Treat.
, vol.82
, pp. 11-16
-
-
Han, S.1
Park, K.2
Bae, B.N.3
-
19
-
-
31044450992
-
Co-regulation of B-Myb expression by E2F1 and EGF receptor
-
Hanada, N., Lo, H.W., Day, C.P., et al. (2006). Co-regulation of B-Myb expression by E2F1 and EGF receptor. Mol. Carcinog. 45, 10-17.
-
(2006)
Mol. Carcinog.
, vol.45
, pp. 10-17
-
-
Hanada, N.1
Lo, H.W.2
Day, C.P.3
-
20
-
-
3042728747
-
Overexpression of E2F1 associated with LOH at RB locus and hyperphosphorylation of RB in non-small cell lung carcinoma
-
Imai, M.A., Oda, Y., Oda, M., et al. (2004). Overexpression of E2F1 associated with LOH at RB locus and hyperphosphorylation of RB in non-small cell lung carcinoma. J. Cancer Res. Clin. Oncol. 130, 320-326.
-
(2004)
J. Cancer Res. Clin. Oncol.
, vol.130
, pp. 320-326
-
-
Imai, M.A.1
Oda, Y.2
Oda, M.3
-
21
-
-
79954423424
-
GRAMD4 mimics p53 and mediates the apoptotic function of p73 at mitochondria
-
John, K., Alla, V., Meier, C., et al. (2011). GRAMD4 mimics p53 and mediates the apoptotic function of p73 at mitochondria. Cell Death Differ. 18, 874-886.
-
(2011)
Cell Death Differ.
, vol.18
, pp. 874-886
-
-
John, K.1
Alla, V.2
Meier, C.3
-
22
-
-
84862907531
-
Regulation of matrix metalloproteinase genes by E2F transcription factors: Rb-Raf-1 interaction as a novel target for metastatic disease
-
Johnson, J.L., Pillai, S., Pernazza, D., et al. (2012). Regulation of matrix metalloproteinase genes by E2F transcription factors: Rb-Raf-1 interaction as a novel target for metastatic disease. Cancer Res. 72, 516-526.
-
(2012)
Cancer Res.
, vol.72
, pp. 516-526
-
-
Johnson, J.L.1
Pillai, S.2
Pernazza, D.3
-
23
-
-
0028938746
-
Expression of the fms-like tyrosine kinase 4 gene becomes restricted to lymphatic endothelium during development
-
Kaipainen, A., Korhonen, J., Mustonen, T., et al. (1995). Expression of the fms-like tyrosine kinase 4 gene becomes restricted to lymphatic endothelium during development. Proc. Natl Acad. Sci. USA 92, 3566-3570.
-
(1995)
Proc. Natl Acad. Sci. USA
, vol.92
, pp. 3566-3570
-
-
Kaipainen, A.1
Korhonen, J.2
Mustonen, T.3
-
24
-
-
78549291781
-
ANCCA/ATAD2 overexpression identifies breast cancer patients with poor prognosis, acting to drive proliferation and survival of triple-negative cells through control of B-Myb and EZH2
-
Kalashnikova, E.V., Revenko, A.S., Gemo, A.T., et al. (2010). ANCCA/ATAD2 overexpression identifies breast cancer patients with poor prognosis, acting to drive proliferation and survival of triple-negative cells through control of B-Myb and EZH2. Cancer Res. 70, 9402-9412.
-
(2010)
Cancer Res.
, vol.70
, pp. 9402-9412
-
-
Kalashnikova, E.V.1
Revenko, A.S.2
Gemo, A.T.3
-
25
-
-
0034041161
-
Missense mutations interfere with VEGFR-3 signalling in primary lymphoedema
-
Karkkainen, M.J., Ferrell, R.E., Lawrence, E.C., et al. (2000). Missense mutations interfere with VEGFR-3 signalling in primary lymphoedema. Nat. Genet. 25, 153-159.
-
(2000)
Nat. Genet.
, vol.25
, pp. 153-159
-
-
Karkkainen, M.J.1
Ferrell, R.E.2
Lawrence, E.C.3
-
26
-
-
68049098116
-
Vascular endothelial growth factor receptor-3 promotes breast cancer cell proliferation, motility and survival in vitro and tumor formation in vivo
-
Kurenova, E.V., Hunt, D.L., He, D., et al. (2009). Vascular endothelial growth factor receptor-3 promotes breast cancer cell proliferation, motility and survival in vitro and tumor formation in vivo. Cell Cycle 8, 2266-2280.
-
(2009)
Cell Cycle
, vol.8
, pp. 2266-2280
-
-
Kurenova, E.V.1
Hunt, D.L.2
He, D.3
-
27
-
-
33846688115
-
Vascular endothelial growth factor receptor 3 is involved in tumor angiogenesis and growth
-
Laakkonen, P., Waltari, M., Holopainen, T., et al. (2007). Vascular endothelial growth factor receptor 3 is involved in tumor angiogenesis and growth. Cancer Res. 67, 593-599.
-
(2007)
Cancer Res.
, vol.67
, pp. 593-599
-
-
Laakkonen, P.1
Waltari, M.2
Holopainen, T.3
-
28
-
-
77954928123
-
Expression signature of E2F1 and its associated genes predict superficial to invasive progression of bladder tumors
-
Lee, J.S., Leem, S.H., Lee, S.Y., et al. (2010). Expression signature of E2F1 and its associated genes predict superficial to invasive progression of bladder tumors. J. Clin. Oncol. 28, 2660-2667.
-
(2010)
J. Clin. Oncol.
, vol.28
, pp. 2660-2667
-
-
Lee, J.S.1
Leem, S.H.2
Lee, S.Y.3
-
29
-
-
31444440292
-
Nuclear EGFR signalling network in cancers: Linking EGFR pathway to cell cycle progression, nitric oxide pathway and patient survival
-
Lo, H.W., and Hung, M.C. (2006). Nuclear EGFR signalling network in cancers: linking EGFR pathway to cell cycle progression, nitric oxide pathway and patient survival. Br. J. Cancer 94, 184-188.
-
(2006)
Br. J. Cancer
, vol.94
, pp. 184-188
-
-
Lo, H.W.1
Hung, M.C.2
-
30
-
-
77957596291
-
The transcription factor E2F1 and the SR protein SC35 control the ratio of pro-angiogenic versus antiangiogenic isoforms of vascular endothelial growth factor-A to inhibit neovascularization in vivo
-
Merdzhanova, G., Gout, S., Keramidas, M., et al. (2010). The transcription factor E2F1 and the SR protein SC35 control the ratio of pro-angiogenic versus antiangiogenic isoforms of vascular endothelial growth factor-A to inhibit neovascularization in vivo. Oncogene 29, 5392-5403.
-
(2010)
Oncogene
, vol.29
, pp. 5392-5403
-
-
Merdzhanova, G.1
Gout, S.2
Keramidas, M.3
-
31
-
-
79958699243
-
ATM and p53 regulate FOXM1 expression via E2F in breast cancer epirubicin treatment and resistance
-
Millour, J., de Olano, N., Horimoto, Y., et al. (2011). ATM and p53 regulate FOXM1 expression via E2F in breast cancer epirubicin treatment and resistance. Mol. Cancer Ther. 10, 1046-1058.
-
(2011)
Mol. Cancer Ther.
, vol.10
, pp. 1046-1058
-
-
Millour, J.1
De Olano, N.2
Horimoto, Y.3
-
32
-
-
70350439869
-
VEGF-C regulates lymphangiogenesis and capillary stability by regulation of PDGF-B
-
Onimaru, M., Yonemitsu, Y., Fujii, T., et al. (2009). VEGF-C regulates lymphangiogenesis and capillary stability by regulation of PDGF-B. Am. J. Physiol. Heart Circ. Physiol. 297, H1685-H1696.
-
(2009)
Am. J. Physiol. Heart Circ. Physiol.
, vol.297
-
-
Onimaru, M.1
Yonemitsu, Y.2
Fujii, T.3
-
33
-
-
77953756024
-
Regulation of vascular endothelial growth factor receptors by Rb and E2F1: Role of acetylation
-
Pillai, S., Kovacs, M., and Chellappan, S. (2010). Regulation of vascular endothelial growth factor receptors by Rb and E2F1: role of acetylation. Cancer Res. 70, 4931-4940.
-
(2010)
Cancer Res.
, vol.70
, pp. 4931-4940
-
-
Pillai, S.1
Kovacs, M.2
Chellappan, S.3
-
34
-
-
84873112147
-
E2F1 apoptosis counterattacked: Evil strikes back
-
Putzer, B.M., and Engelmann, D. (2013). E2F1 apoptosis counterattacked: evil strikes back. Trends Mol. Med. 19, 89-98.
-
(2013)
Trends Mol. Med.
, vol.19
, pp. 89-98
-
-
Putzer, B.M.1
Engelmann, D.2
-
35
-
-
33746610140
-
Cell cycle regulator E2F1 modulates angiogenesis via p53-dependent transcriptional control of VEGF
-
Qin, G., Kishore, R., Dolan, C.M., et al. (2006). Cell cycle regulator E2F1 modulates angiogenesis via p53-dependent transcriptional control of VEGF. Proc. Natl Acad. Sci. USA 103, 11015-11020.
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, pp. 11015-11020
-
-
Qin, G.1
Kishore, R.2
Dolan, C.M.3
-
36
-
-
78649541407
-
Chromatin loading of E2F-MLL complex by cancer-associated coregulator ANCCA via reading a specific histone mark
-
Revenko, A.S., Kalashnikova, E.V., Gemo, A.T., et al. (2010). Chromatin loading of E2F-MLL complex by cancer-associated coregulator ANCCA via reading a specific histone mark. Mol. Cell. Biol. 30, 5260-5272.
-
(2010)
Mol. Cell. Biol.
, vol.30
, pp. 5260-5272
-
-
Revenko, A.S.1
Kalashnikova, E.V.2
Gemo, A.T.3
-
37
-
-
34247102347
-
VEGF and VEGFR-2 (KDR) internalization is required for endothelial recovery during wound healing
-
Santos, S.C., Miguel, C., Domingues, I., et al. (2007). VEGF and VEGFR-2 (KDR) internalization is required for endothelial recovery during wound healing. Exp. Cell Res. 313, 1561-1574.
-
(2007)
Exp. Cell Res.
, vol.313
, pp. 1561-1574
-
-
Santos, S.C.1
Miguel, C.2
Domingues, I.3
-
38
-
-
73649129634
-
Gonadotropin-regulated lymphangiogenesis in ovarian cancer is mediated by LEDGF-induced expression of VEGF-C
-
Sapoznik, S., Cohen, B., Tzuman, Y., et al. (2009). Gonadotropin- regulated lymphangiogenesis in ovarian cancer is mediated by LEDGF-induced expression of VEGF-C. Cancer Res. 69, 9306-9314.
-
(2009)
Cancer Res.
, vol.69
, pp. 9306-9314
-
-
Sapoznik, S.1
Cohen, B.2
Tzuman, Y.3
-
39
-
-
78649888666
-
The retinoblastoma tumor suppressor controls androgen signaling and human prostate cancer progression
-
Sharma, A., Yeow, W.S., Ertel, A., et al. (2010). The retinoblastoma tumor suppressor controls androgen signaling and human prostate cancer progression. J. Clin. Invest. 120, 4478-4492.
-
(2010)
J. Clin. Invest.
, vol.120
, pp. 4478-4492
-
-
Sharma, A.1
Yeow, W.S.2
Ertel, A.3
-
40
-
-
40249103622
-
Hypoxiainduced epithelial VEGF-C/VEGFR-3 upregulation in carcinoma cell lines
-
Simiantonaki, N., Jayasinghe, C., Michel-Schmidt, R., et al. (2008). Hypoxiainduced epithelial VEGF-C/VEGFR-3 upregulation in carcinoma cell lines. Int. J. Oncol. 32, 585-592.
-
(2008)
Int. J. Oncol.
, vol.32
, pp. 585-592
-
-
Simiantonaki, N.1
Jayasinghe, C.2
Michel-Schmidt, R.3
-
41
-
-
0035122537
-
Induction of tumor lymphangiogenesisby VEGF-Cpromotesbreast cancermetastasis
-
Skobe, M., Hawighorst, T., Jackson, D.G., et al. (2001). Induction of tumor lymphangiogenesisby VEGF-Cpromotesbreast cancermetastasis. Nat. Med.7,192-198.
-
(2001)
Nat. Med.
, vol.7
, pp. 192-198
-
-
Skobe, M.1
Hawighorst, T.2
Jackson, D.G.3
-
42
-
-
0037089150
-
Gene expression changes in response to E2F1 activation
-
Stanelle, J., Stiewe, T., Theseling, C.C., et al. (2002). Gene expression changes in response to E2F1 activation. Nucleic Acids Res. 30, 1859-1867.
-
(2002)
Nucleic Acids Res.
, vol.30
, pp. 1859-1867
-
-
Stanelle, J.1
Stiewe, T.2
Theseling, C.C.3
-
43
-
-
33644822574
-
The VEGF-C/Flt-4 axis promotes invasion and metastasis of cancer cells
-
Su, J.L., Yang, P.C., Shih, J.Y., et al. (2006). The VEGF-C/Flt-4 axis promotes invasion and metastasis of cancer cells. Cancer Cell 9, 209-223.
-
(2006)
Cancer Cell
, vol.9
, pp. 209-223
-
-
Su, J.L.1
Yang, P.C.2
Shih, J.Y.3
-
44
-
-
33847198622
-
The role of the VEGF-C/VEGFR-3 axis in cancer progression
-
Su, J.L., Yen, C.J., Chen, P.S., et al. (2007). The role of the VEGF-C/VEGFR-3 axis in cancer progression. Br. J. Cancer 96, 541-545.
-
(2007)
Br. J. Cancer
, vol.96
, pp. 541-545
-
-
Su, J.L.1
Yen, C.J.2
Chen, P.S.3
-
45
-
-
15244341029
-
Roles of vascular endothelial growth factor receptor 3 signaling in differentiation of mouse embryonic stem cell-derived vascular progenitor cells into endothelial cells
-
Suzuki, H., Watabe, T., Kato, M., et al. (2005). Roles of vascular endothelial growth factor receptor 3 signaling in differentiation of mouse embryonic stem cell-derived vascular progenitor cells into endothelial cells. Blood 105, 2372-2379.
-
(2005)
Blood
, vol.105
, pp. 2372-2379
-
-
Suzuki, H.1
Watabe, T.2
Kato, M.3
-
46
-
-
48349129069
-
Blocking VEGFR-3 suppresses angiogenic sprouting and vascular network formation
-
Tammela, T., Zarkada, G., Wallgard, E., et al. (2008). Blocking VEGFR-3 suppresses angiogenic sprouting and vascular network formation. Nature 454, 656-660.
-
(2008)
Nature
, vol.454
, pp. 656-660
-
-
Tammela, T.1
Zarkada, G.2
Wallgard, E.3
|