Functional interplay between E2F1 and chemotherapeutic drugs defines immediate E2F1 target genes crucial for cancer cell death

Cellular and Molecular Life Sciences

Volumn 67, Issue 6, 2010, Pages 931-948

  Engelmann, David ^a   Knoll, Susanne ^a   Ewerth, Daniel ^a   Steder, Marc ^a   Stoll, Anja ^a   Pützer, Brigitte M ^a  

^a UNIVERSITY OF ROSTOCK   (Germany)

Author keywords

Cancer; Cell death; Chemotherapy; Cooperation response genes; E2F1; TIEGL KLF10

Indexed keywords

4 HYDROXYTAMOXIFEN; CISPLATIN; DOXORUBICIN; GEMCITABINE; KRUPPEL LIKE FACTOR; KRUPPEL LIKE FACTOR 10; TRANSCRIPTION FACTOR E2F1; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; E2F1 PROTEIN, HUMAN; EARLY GROWTH RESPONSE FACTOR; KLF10 PROTEIN, HUMAN;

APOPTOSIS; ARTICLE; CANCER CELL; CHEMOSENSITIVITY; CLUSTER ANALYSIS; CONTROLLED STUDY; DNA DAMAGE; DRUG CYTOTOXICITY; GENE EXPRESSION; GENE TARGETING; GENOTOXICITY; HUMAN; HUMAN CELL; MICROARRAY ANALYSIS; NUCLEOTIDE SEQUENCE; OSTEOSARCOMA CELL; TRANSCRIPTION INITIATION; UNINDEXED SEQUENCE; CELL DEATH; DNA MICROARRAY; DRUG EFFECT; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; NEOPLASM; PATHOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR CELL CULTURE;

ANTINEOPLASTIC AGENTS; CELL DEATH; CLUSTER ANALYSIS; E2F1 TRANSCRIPTION FACTOR; EARLY GROWTH RESPONSE TRANSCRIPTION FACTORS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; KRUPPEL-LIKE TRANSCRIPTION FACTORS; NEOPLASMS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TUMOR CELLS, CULTURED;

EID: 77949529981     PISSN: 1420682X     EISSN: 14209071     Source Type: Journal    
DOI: 10.1007/s00018-009-0222-0     Document Type: Article

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