Skeletal muscle-derived myonectin activates the mammalian target of rapamycin (mTOR) pathway to suppress autophagy in liver

Journal of Biological Chemistry

Volumn 288, Issue 50, 2013, Pages 36073-36082

  Seldin, Marcus M ^a   Lei, Xia ^a   Tan, Stefanie Y ^a   Stanson, Kevin P ^a   Wei, Zhikui ^a   Wong, G William ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENERGY HOMEOSTASIS; FOOD DEPRIVATIONS; HORMONAL SIGNALS; MAMMALIAN TARGET OF RAPAMYCIN (MTOR); METABOLIC STATE; PROTEIN DEGRADATION; RECYCLING PATHWAYS; SIGNALING PATHWAYS;

GENE EXPRESSION; MUSCLE; NUTRIENTS; TISSUE HOMEOSTASIS;

ANTIBIOTICS;

MAMMALIAN TARGET OF RAPAMYCIN; MICROTUBULE ASSOCIATED PROTEIN; MICROTUBULE ASSOCIATED PROTEIN LIGHT CHAIN 3; MUSCLE PROTEIN; MYONECTIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN P62; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; CONTROLLED STUDY; CORRELATION ANALYSIS; DIET SUPPLEMENTATION; ENERGY BALANCE; FOOD DEPRIVATION; HUMAN; HUMAN CELL; LIVER CELL; LIVER CELL CULTURE; LIVER PARENCHYMA; MOLECULAR INTERACTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SKELETAL MUSCLE; STARVATION;

AUTOPHAGY; LIVER; LIVER METABOLISM; MTOR; SKELETAL MUSCLE;

ANIMALS; AUTOPHAGY; CELL LINE; CYTOKINES; DIETARY SUPPLEMENTS; GENE EXPRESSION REGULATION; HOMEOSTASIS; HUMANS; LIVER; MALE; MICE; MICROTUBULE-ASSOCIATED PROTEINS; MUSCLE PROTEINS; MUSCLE, SKELETAL; PROTEOLYSIS; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; STARVATION; TOR SERINE-THREONINE KINASES; TRANSCRIPTION FACTORS;

EID: 84890319864     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.500736     Document Type: Article

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