메뉴 건너뛰기




Volumn 14, Issue 1, 2014, Pages 75-101

Targeting TNF-α for the treatment of inflammatory bowel disease

Author keywords

Adalimumab; Anti TNF; Certolizumab pegol; Combination therapy; Crohn's disease; Efficacy; Golimumab; Immunogenicity; Inflammatory bowel disease; Infliximab; Mucosal healing; Safety; Therapeutic drug monitoring; TNF angatonists; Ulcerative colitis; Window of opportunity

Indexed keywords

ADALIMUMAB; AZATHIOPRINE; CELL ADHESION MOLECULE; CERTOLIZUMAB PEGOL; CORTICOSTEROID; GOLIMUMAB; INFLIXIMAB; MERCAPTOPURINE; METHOTREXATE; PLACEBO; TUMOR NECROSIS FACTOR ANTIBODY;

EID: 84890148956     PISSN: 14712598     EISSN: None     Source Type: Journal    
DOI: 10.1517/14712598.2014.858695     Document Type: Review
Times cited : (125)

References (163)
  • 2
  • 3
    • 38549176118 scopus 로고    scopus 로고
    • Tumor necrosis factor antagonist mechanisms of action: A comprehensive review
    • Tracey D, Klareskog L, Sasso EH, et al. Tumor necrosis factor antagonist mechanisms of action: a comprehensive review. Pharmacol Ther 2008;117:244-79
    • (2008) Pharmacol Ther , vol.117 , pp. 244-279
    • Tracey, D.1    Klareskog, L.2    Sasso, E.H.3
  • 4
    • 0027186553 scopus 로고
    • Cytokines in stools of children with inflammatory bowel disease or infective diarrhoea
    • Nicholls S, Stephens S, Braegger CP, et al. Cytokines in stools of children with inflammatory bowel disease or infective diarrhoea. J Clin Pathol 1993;46:757-60
    • (1993) J Clin Pathol , vol.46 , pp. 757-760
    • Nicholls, S.1    Stephens, S.2    Braegger, C.P.3
  • 5
    • 0028236232 scopus 로고
    • Tumor necrosis factor alphaproducing cells in the intestinal mucosa of children with inflammatory bowel disease
    • Breese EJ, Michie CA, Nicholls SW, et al. Tumor necrosis factor alphaproducing cells in the intestinal mucosa of children with inflammatory bowel disease. Gastroenterology 1994;106:1455-66
    • (1994) Gastroenterology , vol.106 , pp. 1455-1466
    • Breese, E.J.1    Michie, C.A.2    Nicholls, S.W.3
  • 6
    • 0034956578 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha in serum of patients with inflammatory bowel disease as measured by a highly sensitive immuno-PCR
    • Komatsu M, Kobayashi D, Saito K, et al. Tumor necrosis factor-alpha in serum of patients with inflammatory bowel disease as measured by a highly sensitive immuno-PCR. Clin Chem 2001;47:1297-301
    • (2001) Clin Chem , vol.47 , pp. 1297-1301
    • Komatsu, M.1    Kobayashi, D.2    Saito, K.3
  • 7
    • 33748861764 scopus 로고    scopus 로고
    • A new generation of high-affinity humanized PEGylated Fab́ fragment anti-tumor necrosis factor-a monoclonal antibodies
    • Weir N, Athwal D, Brown D, et al. A new generation of high-affinity humanized PEGylated Fab́ fragment anti-tumor necrosis factor-a monoclonal antibodies. Therapy 2006;3:521-6
    • (2006) Therapy , vol.3 , pp. 521-526
    • Weir, N.1    Athwal, D.2    Brown, D.3
  • 8
    • 0034754477 scopus 로고    scopus 로고
    • Etanercept for active Crohn's disease: A randomized, double-blind, placebocontrolled trial
    • Sandborn WJ, Hanauer SB, Katz S, et al. Etanercept for active Crohn's disease: a randomized, double-blind, placebocontrolled trial. Gastroenterology 2001;121:1088-94
    • (2001) Gastroenterology , vol.121 , pp. 1088-1094
    • Sandborn, W.J.1    Hanauer, S.B.2    Katz, S.3
  • 9
    • 0036229932 scopus 로고    scopus 로고
    • Binding and functional comparisons of two types of tumor necrosis factor antagonists
    • Scallon B, Cai A, Solowski N, et al. Binding and functional comparisons of two types of tumor necrosis factor antagonists. J Pharmacol Exp Ther 2002;301:418-26
    • (2002) J Pharmacol Exp Ther , vol.301 , pp. 418-426
    • Scallon, B.1    Cai, A.2    Solowski, N.3
  • 10
    • 77958520182 scopus 로고    scopus 로고
    • Characterization of golimumab, a human monoclonal antibody specific for human tumor necrosis factor alpha
    • Shealy D, Cai A, Staquet K, et al. Characterization of golimumab, a human monoclonal antibody specific for human tumor necrosis factor alpha. MAbs 2010;2:428-39
    • (2010) MAbs , vol.2 , pp. 428-439
    • Shealy, D.1    Cai, A.2    Staquet, K.3
  • 11
    • 84876372616 scopus 로고    scopus 로고
    • Reduction of CD68+ macrophages and decreased IL-17 expression in intestinal mucosa of patients with inflammatory bowel disease strongly correlate with endoscopic response and mucosal healing following infliximab therapy
    • Caprioli F, Bose F, Rossi RL, et al. Reduction of CD68+ macrophages and decreased IL-17 expression in intestinal mucosa of patients with inflammatory bowel disease strongly correlate with endoscopic response and mucosal healing following infliximab therapy. Inflamm Bowel Dis 2013;19:729-39
    • (2013) Inflamm Bowel Dis , vol.19 , pp. 729-739
    • Caprioli, F.1    Bose, F.2    Rossi, R.L.3
  • 12
    • 0036151047 scopus 로고    scopus 로고
    • Infliximab treatment induces apoptosis of lamina propria T lymphocytes in Crohn's disease
    • ten Hove T, van Montfrans C, Peppelenbosch MP, van Deventer SJ. Infliximab treatment induces apoptosis of lamina propria T lymphocytes in Crohn's disease. Gut 2002;50:206-11
    • (2002) Gut , vol.50 , pp. 206-211
    • Ten Hove, T.1    Van Montfrans, C.2    Peppelenbosch, M.P.3    Van Deventer, S.J.4
  • 13
    • 0343674489 scopus 로고    scopus 로고
    • Reduction of chemokine levels and leukocyte traffic to joints by tumor necrosis factor alpha blockade in patients with rheumatoid arthritis
    • Taylor PC, Peters AM, Paleolog E, et al. Reduction of chemokine levels and leukocyte traffic to joints by tumor necrosis factor alpha blockade in patients with rheumatoid arthritis. Arthritis Rheum 2000;43:38-47
    • (2000) Arthritis Rheum , vol.43 , pp. 38-47
    • Taylor, P.C.1    Peters, A.M.2    Paleolog, E.3
  • 14
    • 0030981088 scopus 로고    scopus 로고
    • Tumour necrosis factor and Crohn's disease
    • Van Deventer SJ. Tumour necrosis factor and Crohn's disease. Gut 1997;40:443-8
    • (1997) Gut , vol.40 , pp. 443-448
    • Van Deventer, S.J.1
  • 15
    • 0029004771 scopus 로고
    • Chimeric anti-TNF-alpha monoclonal antibody cA2 binds recombinant transmembrane TNF-alpha and activates immune effector functions
    • Scallon BJ, Moore MA, Trinh H, et al. Chimeric anti-TNF-alpha monoclonal antibody cA2 binds recombinant transmembrane TNF-alpha and activates immune effector functions. Cytokine 1995;7:251-9
    • (1995) Cytokine , vol.7 , pp. 251-259
    • Scallon, B.J.1    Moore, M.A.2    Trinh, H.3
  • 16
    • 84857373545 scopus 로고    scopus 로고
    • Regulatory macrophages induced by infliximab are involved in healing in vivo and in vitro
    • Vos AC, Wildenberg ME, Arijs I, et al. Regulatory macrophages induced by infliximab are involved in healing in vivo and in vitro. Inflamm Bowel Dis 2012;18:401-8
    • (2012) Inflamm Bowel Dis , vol.18 , pp. 401-408
    • Vos, A.C.1    Wildenberg, M.E.2    Arijs, I.3
  • 17
    • 0027231774 scopus 로고
    • Tumour-necrosis-factor antibody treatment in Crohn's disease
    • Derkx B, Taminiau J, Radema S, et al. Tumour-necrosis-factor antibody treatment in Crohn's disease. Lancet 1993;342:173-4
    • (1993) Lancet , vol.342 , pp. 173-174
    • Derkx, B.1    Taminiau, J.2    Radema, S.3
  • 18
    • 0028143211 scopus 로고
    • Randomised double-blind comparison of chimeric monoclonal antibody to tumour necrosis factor alpha (cA2) versus placebo in rheumatoid arthritis
    • Elliott MJ, Maini RN, Feldmann M, et al. Randomised double-blind comparison of chimeric monoclonal antibody to tumour necrosis factor alpha (cA2) versus placebo in rheumatoid arthritis. Lancet 1994;344:1105-10
    • (1994) Lancet , vol.344 , pp. 1105-1110
    • Elliott, M.J.1    Maini, R.N.2    Feldmann, M.3
  • 19
    • 75149129948 scopus 로고    scopus 로고
    • The second European evidence-based consensus on the diagnosis and management of Crohn's disease: Definitions and diagnosis
    • Van Assche G, Dignass A, Panes J, et al. The second European evidence-based consensus on the diagnosis and management of Crohn's disease: definitions and diagnosis. J Crohns Colitis 2010;4:7-27
    • (2010) J Crohns Colitis , vol.4 , pp. 7-27
    • Van Assche, G.1    Dignass, A.2    Panes, J.3
  • 20
    • 0036161216 scopus 로고    scopus 로고
    • A review of activity indices and efficacy endpoints for clinical trials of medical therapy in adults with Crohn's disease
    • Sandborn WJ, Feagan BG, Hanauer SB, et al. A review of activity indices and efficacy endpoints for clinical trials of medical therapy in adults with Crohn's disease. Gastroenterology 2002;122:512-30
    • (2002) Gastroenterology , vol.122 , pp. 512-530
    • Sandborn, W.J.1    Feagan, B.G.2    Hanauer, S.B.3
  • 21
    • 0037018761 scopus 로고    scopus 로고
    • Maintenance infliximab for Crohn's disease: The ACCENT i randomised trial
    • Hanauer SB, Feagan BG, Lichtenstein GR, et al. Maintenance infliximab for Crohn's disease: the ACCENT I randomised trial. Lancet 2002;359:1541-9
    • (2002) Lancet , vol.359 , pp. 1541-1549
    • Hanauer, S.B.1    Feagan, B.G.2    Lichtenstein, G.R.3
  • 22
    • 10744224387 scopus 로고    scopus 로고
    • Comparison of scheduled and episodic treatment strategies of infliximab in Crohn's disease
    • Rutgeerts P, Feagan BG, Lichtenstein GR, et al. Comparison of scheduled and episodic treatment strategies of infliximab in Crohn's disease. Gastroenterology 2004;126:402-13
    • (2004) Gastroenterology , vol.126 , pp. 402-413
    • Rutgeerts, P.1    Feagan, B.G.2    Lichtenstein, G.R.3
  • 23
    • 0030954732 scopus 로고    scopus 로고
    • A short-term study of chimeric monoclonal antibody cA2 to tumor necrosis factor alpha for Crohn's disease Crohn's disease cA2 Study Group
    • Targan SR, Hanauer SB, van Deventer SJ, et al. A short-term study of chimeric monoclonal antibody cA2 to tumor necrosis factor alpha for Crohn's disease. Crohn's disease cA2 Study Group. N Engl J Med 1997;337:1029-35
    • (1997) N Engl J Med , vol.337 , pp. 1029-1035
    • Targan, S.R.1    Hanauer, S.B.2    Van Deventer, S.J.3
  • 24
    • 0032833517 scopus 로고    scopus 로고
    • Efficacy and safety of retreatment with anti-tumor necrosis factor antibody (infliximab) to maintain remission in Crohn's disease
    • Rutgeerts P, D'Haens G, Targan S, et al. Efficacy and safety of retreatment with anti-tumor necrosis factor antibody (infliximab) to maintain remission in Crohn's disease. Gastroenterology 1999;117:761-9
    • (1999) Gastroenterology , vol.117 , pp. 761-769
    • Rutgeerts, P.1    D'haens, G.2    Targan, S.3
  • 25
    • 33645958908 scopus 로고    scopus 로고
    • Infliximab plus azathioprine for steroiddependent Crohn's disease patients: A randomized placebo-controlled trial
    • Lemann M, Mary JY, Duclos B, et al. Infliximab plus azathioprine for steroiddependent Crohn's disease patients: a randomized placebo-controlled trial. Gastroenterology 2006;130:1054-61
    • (2006) Gastroenterology , vol.130 , pp. 1054-1061
    • Lemann, M.1    Mary, J.Y.2    Duclos, B.3
  • 26
    • 77950988234 scopus 로고    scopus 로고
    • Infliximab, azathioprine, or combination therapy for Crohn's disease
    • Colombel JF, Sandborn WJ, Reinisch W, et al. Infliximab, azathioprine, or combination therapy for Crohn's disease. N Engl J Med 2010;362:1383-95
    • (2010) N Engl J Med , vol.362 , pp. 1383-1395
    • Colombel, J.F.1    Sandborn, W.J.2    Reinisch, W.3
  • 27
    • 32044451548 scopus 로고    scopus 로고
    • Human anti-tumor necrosis factor monoclonal antibody (adalimumab) in Crohn's disease: The CLASSIC-I trial
    • Hanauer SB, Sandborn WJ, Rutgeerts P, et al. Human anti-tumor necrosis factor monoclonal antibody (adalimumab) in Crohn's disease: the CLASSIC-I trial. Gastroenterology 2006;130:323-33
    • (2006) Gastroenterology , vol.130 , pp. 323-333
    • Hanauer, S.B.1    Sandborn, W.J.2    Rutgeerts, P.3
  • 28
    • 33846242958 scopus 로고    scopus 로고
    • Adalimumab for maintenance of clinical response and remission in patients with Crohn's disease: The CHARM trial
    • Colombel JF, Sandborn WJ, Rutgeerts P, et al. Adalimumab for maintenance of clinical response and remission in patients with Crohn's disease: the CHARM trial. Gastroenterology 2007;132:52-65
    • (2007) Gastroenterology , vol.132 , pp. 52-65
    • Colombel, J.F.1    Sandborn, W.J.2    Rutgeerts, P.3
  • 29
    • 34347402306 scopus 로고    scopus 로고
    • Adalimumab induction therapy for Crohn disease previously treated with infliximab: A randomized trial
    • Sandborn WJ, Rutgeerts P, Enns R, et al. Adalimumab induction therapy for Crohn disease previously treated with infliximab: a randomized trial. Ann Intern Med 2007;146:829-38
    • (2007) Ann Intern Med , vol.146 , pp. 829-838
    • Sandborn, W.J.1    Rutgeerts, P.2    Enns, R.3
  • 30
    • 34249281002 scopus 로고    scopus 로고
    • Adalimumab for maintenance treatment of Crohn's disease: Results of the CLASSIC II trial
    • Sandborn WJ, Hanauer SB, Rutgeerts P, et al. Adalimumab for maintenance treatment of Crohn's disease: results of the CLASSIC II trial. Gut 2007;56:1232-9
    • (2007) Gut , vol.56 , pp. 1232-1239
    • Sandborn, W.J.1    Hanauer, S.B.2    Rutgeerts, P.3
  • 31
    • 34447523749 scopus 로고    scopus 로고
    • Certolizumab pegol for the treatment of Crohn's disease
    • Sandborn WJ, Feagan BG, Stoinov S, et al. Certolizumab pegol for the treatment of Crohn's disease. N Engl J Med 2007;357:228-38
    • (2007) N Engl J Med , vol.357 , pp. 228-238
    • Sandborn, W.J.1    Feagan, B.G.2    Stoinov, S.3
  • 32
    • 79960498782 scopus 로고    scopus 로고
    • Certolizumab pegol for active Crohn's disease: A placebo-controlled, randomized trial
    • e3
    • Sandborn WJ, Schreiber S, Feagan BG, et al. Certolizumab pegol for active Crohn's disease: a placebo-controlled, randomized trial. Clin Gastroenterol Hepatol 2011;9:670-8; e3
    • (2011) Clin Gastroenterol Hepatol , vol.9 , pp. 670-678
    • Sandborn, W.J.1    Schreiber, S.2    Feagan, B.G.3
  • 33
    • 34447515607 scopus 로고    scopus 로고
    • Maintenance therapy with certolizumab pegol for Crohn's disease
    • Schreiber S, Khaliq-Kareemi M, Lawrance IC, et al. Maintenance therapy with certolizumab pegol for Crohn's disease. N Engl J Med 2007;357:239-50
    • (2007) N Engl J Med , vol.357 , pp. 239-250
    • Schreiber, S.1    Khaliq-Kareemi, M.2    Lawrance, I.C.3
  • 34
    • 77955277832 scopus 로고    scopus 로고
    • Certolizumab pegol in patients with moderate to severe Crohn's disease and secondary failure to infliximab
    • e2
    • Sandborn WJ, Abreu MT, D'Haens G, et al. Certolizumab pegol in patients with moderate to severe Crohn's disease and secondary failure to infliximab. Clin Gastroenterol Hepatol 2010;8:688-95; e2
    • (2010) Clin Gastroenterol Hepatol , vol.8 , pp. 688-695
    • Sandborn, W.J.1    Abreu, M.T.2    D'haens, G.3
  • 35
    • 0033529049 scopus 로고    scopus 로고
    • Infliximab for the treatment of fistulas in patients with Crohn's disease
    • Present DH, Rutgeerts P, Targan S, et al. Infliximab for the treatment of fistulas in patients with Crohn's disease. N Engl J Med 1999;340:1398-405
    • (1999) N Engl J Med , vol.340 , pp. 1398-1405
    • Present, D.H.1    Rutgeerts, P.2    Targan, S.3
  • 36
    • 5044235159 scopus 로고    scopus 로고
    • Long-term treatment of rectovaginal fistulas in Crohn's disease: Response to infliximab in the ACCENT II Study
    • Sands BE, Blank MA, Patel K, van Deventer SJ. Long-term treatment of rectovaginal fistulas in Crohn's disease: response to infliximab in the ACCENT II Study. Clin Gastroenterol Hepatol 2004;2:912-20
    • (2004) Clin Gastroenterol Hepatol , vol.2 , pp. 912-920
    • Sands, B.E.1    Blank, M.A.2    Patel, K.3    Van Deventer, S.J.4
  • 37
    • 11144346129 scopus 로고    scopus 로고
    • Clinical and endosonographic effect of ciprofloxacin on the treatment of perianal fistulae in Crohn's disease with infliximab: A double-blind placebo-controlled study
    • West RL, van der Woude CJ, Hansen BE, et al. Clinical and endosonographic effect of ciprofloxacin on the treatment of perianal fistulae in Crohn's disease with infliximab: a double-blind placebo-controlled study. Aliment Pharmacol Ther 2004;20:1329-36
    • (2004) Aliment Pharmacol Ther , vol.20 , pp. 1329-1336
    • West, R.L.1    Van Der Woude, C.J.2    Hansen, B.E.3
  • 38
    • 33845188387 scopus 로고    scopus 로고
    • Fistulating anal Crohn's disease: Results of combined surgical and infliximab treatment
    • Hyder SA, Travis SP, Jewell DP, et al. Fistulating anal Crohn's disease: results of combined surgical and infliximab treatment. Dis Colon Rectum 2006;49:1837-41
    • (2006) Dis Colon Rectum , vol.49 , pp. 1837-1841
    • Hyder, S.A.1    Travis, S.P.2    Jewell, D.P.3
  • 39
    • 67649951542 scopus 로고    scopus 로고
    • Predicting factors of fistula healing and clinical remission after infliximabbased combined therapy for perianal fistulizing Crohn's disease
    • Tougeron D, Savoye G, Savoye-Collet C, et al. Predicting factors of fistula healing and clinical remission after infliximabbased combined therapy for perianal fistulizing Crohn's disease. Dig Dis Sci 2009;54:1746-52
    • (2009) Dig Dis Sci , vol.54 , pp. 1746-1752
    • Tougeron, D.1    Savoye, G.2    Savoye-Collet, C.3
  • 40
    • 79751472562 scopus 로고    scopus 로고
    • The London Position Statement of the World Congress of Gastroenterology on Biological Therapy for IBD with the European Crohn's and Colitis Organization: When to start, when to stop, which drug to choose, and how to predict response?
    • D'Haens GR, Panaccione R, Higgins PD, et al. The London Position Statement of the World Congress of Gastroenterology on Biological Therapy for IBD with the European Crohn's and Colitis Organization: when to start, when to stop, which drug to choose, and how to predict response? Am J Gastroenterol 2011;106:199-212
    • (2011) Am J Gastroenterol , vol.106 , pp. 199-212
    • D'haens, G.R.1    Panaccione, R.2    Higgins, P.D.3
  • 41
    • 0034777502 scopus 로고    scopus 로고
    • Infliximab in the treatment of severe, steroid-refractory ulcerative colitis: A pilot study
    • Sands BE, Tremaine WJ, Sandborn WJ, et al. Infliximab in the treatment of severe, steroid-refractory ulcerative colitis: a pilot study. Inflamm Bowel Dis 2001;7:83-8
    • (2001) Inflamm Bowel Dis , vol.7 , pp. 83-88
    • Sands, B.E.1    Tremaine, W.J.2    Sandborn, W.J.3
  • 42
    • 20444479336 scopus 로고    scopus 로고
    • Infliximab as rescue therapy in severe to moderately severe ulcerative colitis: A randomized, placebo-controlled study
    • Jarnerot G, Hertervig E, Friis-Liby I, et al. Infliximab as rescue therapy in severe to moderately severe ulcerative colitis: a randomized, placebo-controlled study. Gastroenterology 2005;128:1805-11
    • (2005) Gastroenterology , vol.128 , pp. 1805-1811
    • Jarnerot, G.1    Hertervig, E.2    Friis-Liby, I.3
  • 43
    • 28844473957 scopus 로고    scopus 로고
    • Infliximab for induction and maintenance therapy for ulcerative colitis
    • Rutgeerts P, Sandborn WJ, Feagan BG, et al. Infliximab for induction and maintenance therapy for ulcerative colitis. N Engl J Med 2005;353:2462-76
    • (2005) N Engl J Med , vol.353 , pp. 2462-2476
    • Rutgeerts, P.1    Sandborn, W.J.2    Feagan, B.G.3
  • 44
    • 70349418632 scopus 로고    scopus 로고
    • Colectomy rate comparison after treatment of ulcerative colitis with placebo or infliximab
    • Sandborn WJ, Rutgeerts P, Feagan BG, et al. Colectomy rate comparison after treatment of ulcerative colitis with placebo or infliximab. Gastroenterology 2009;137:1250-60
    • (2009) Gastroenterology , vol.137 , pp. 1250-1260
    • Sandborn, W.J.1    Rutgeerts, P.2    Feagan, B.G.3
  • 45
    • 84855674281 scopus 로고    scopus 로고
    • Long-term infliximab maintenance therapy for ulcerative colitis: The ACT-1 and -2 extension studies
    • Reinisch W, Sandborn WJ, Rutgeerts P, et al. Long-term infliximab maintenance therapy for ulcerative colitis: the ACT-1 and -2 extension studies. Inflamm Bowel Dis 2012;18:201-11
    • (2012) Inflamm Bowel Dis , vol.18 , pp. 201-211
    • Reinisch, W.1    Sandborn, W.J.2    Rutgeerts, P.3
  • 46
    • 48949099032 scopus 로고    scopus 로고
    • Long-term outcome after infliximab for refractory ulcerative colitis
    • Ferrante M, Vermeire S, Fidder H, et al. Long-term outcome after infliximab for refractory ulcerative colitis. J Crohns Colitis 2008;2:219-25
    • (2008) J Crohns Colitis , vol.2 , pp. 219-225
    • Ferrante, M.1    Vermeire, S.2    Fidder, H.3
  • 47
    • 78649893669 scopus 로고    scopus 로고
    • A multicenter experience with infliximab for ulcerative colitis: Outcomes and predictors of response, optimization, colectomy, and hospitalization
    • Oussalah A, Evesque L, Laharie D, et al. A multicenter experience with infliximab for ulcerative colitis: outcomes and predictors of response, optimization, colectomy, and hospitalization. Am J Gastroenterol 2010;105:2617-25
    • (2010) Am J Gastroenterol , vol.105 , pp. 2617-2625
    • Oussalah, A.1    Evesque, L.2    Laharie, D.3
  • 48
    • 84876378296 scopus 로고    scopus 로고
    • Infliximab in steroid-dependent ulcerative colitis: Effectiveness and predictors of clinical and endoscopic remission
    • Armuzzi A, Pugliese D, Danese S, et al. Infliximab in steroid-dependent ulcerative colitis: effectiveness and predictors of clinical and endoscopic remission. Inflamm Bowel Dis 2013;19:1065-72
    • (2013) Inflamm Bowel Dis , vol.19 , pp. 1065-1072
    • Armuzzi, A.1    Pugliese, D.2    Danese, S.3
  • 49
    • 84870293844 scopus 로고    scopus 로고
    • Ciclosporin versus infliximab in patients with severe ulcerative colitis refractory to intravenous steroids: A parallel, open-label randomised controlled trial
    • Laharie D, Bourreille A, Branche J, et al. Ciclosporin versus infliximab in patients with severe ulcerative colitis refractory to intravenous steroids: a parallel, open-label randomised controlled trial. Lancet 2012;380:1909-15
    • (2012) Lancet , vol.380 , pp. 1909-1915
    • Laharie, D.1    Bourreille, A.2    Branche, J.3
  • 50
    • 79955859430 scopus 로고    scopus 로고
    • Adalimumab for induction of clinical remission in moderately to severely active ulcerative colitis: Results of a randomised controlled trial
    • Reinisch W, Sandborn WJ, Hommes DW, et al. Adalimumab for induction of clinical remission in moderately to severely active ulcerative colitis: results of a randomised controlled trial. Gut 2011;60:780-7
    • (2011) Gut , vol.60 , pp. 780-787
    • Reinisch, W.1    Sandborn, W.J.2    Hommes, D.W.3
  • 51
    • 84856163835 scopus 로고    scopus 로고
    • Adalimumab induces and maintains clinical remission in patients with moderate-to-severe ulcerative colitis
    • e1-3
    • Sandborn WJ, van Assche G, Reinisch W, et al. Adalimumab induces and maintains clinical remission in patients with moderate-to-severe ulcerative colitis. Gastroenterology 2012;142:257-65; e1-3
    • (2012) Gastroenterology , vol.142 , pp. 257-265
    • Sandborn, W.J.1    Van Assche, G.2    Reinisch, W.3
  • 52
    • 84884575642 scopus 로고    scopus 로고
    • 52-week efficacy of adalimumab in patients with moderately to severely active ulcerative colitis who failed corticosteroids and/or immunosuppressants
    • Reinisch W, Sandborn WJ, Panaccione R, et al. 52-week efficacy of adalimumab in patients with moderately to severely active ulcerative colitis who failed corticosteroids and/or immunosuppressants. Inflamm Bowel Dis 2013;19:1700-9
    • (2013) Inflamm Bowel Dis , vol.19 , pp. 1700-1709
    • Reinisch, W.1    Sandborn, W.J.2    Panaccione, R.3
  • 53
    • 84872832486 scopus 로고    scopus 로고
    • One-year maintenance outcomes among patients with moderately-to-severely active ulcerative colitis who responded to induction therapy with adalimumab: Subgroup analyses from ULTRA 2
    • Sandborn WJ, Colombel JF, D'Haens G, et al. One-year maintenance outcomes among patients with moderately-to-severely active ulcerative colitis who responded to induction therapy with adalimumab: subgroup analyses from ULTRA 2. Aliment Pharmacol Ther 2013;37:204-13
    • (2013) Aliment Pharmacol Ther , vol.37 , pp. 204-213
    • Sandborn, W.J.1    Colombel, J.F.2    D'haens, G.3
  • 54
    • 84890620601 scopus 로고    scopus 로고
    • Subcutaneous golimumab induces clinical response and remission in patients with moderate to severe ulcerative colitis
    • published online 2 June 2013; doi: 10.1053/j.gastro.2013.05.048
    • Sandborn WJ, Feagan BG, Marano C, et al. Subcutaneous Golimumab Induces Clinical Response and Remission in Patients With Moderate to Severe Ulcerative Colitis. Gastroenterology 2013;published online 2 June 2013; doi: 10.1053/j.gastro.2013.05.048
    • (2013) Gastroenterology
    • Sandborn, W.J.1    Feagan, B.G.2    Marano, C.3
  • 55
    • 84890629055 scopus 로고    scopus 로고
    • Subcutaneous golimumab maintains clinical response in patients with moderate-to-severe ulcerative colitis
    • published online 19 june 2013; doi:10.1053/j.gastro.2013.06.010
    • Sandborn WJ, Feagan BG, Marano C, et al. Subcutaneous Golimumab Maintains Clinical Response in Patients with Moderate-To-Severe Ulcerative Colitis. Gastroenterology 2013;published online 19 june 2013; doi:10.1053/j.gastro.2013. 06.010
    • (2013) Gastroenterology
    • Sandborn, W.J.1    Feagan, B.G.2    Marano, C.3
  • 57
    • 3042819216 scopus 로고    scopus 로고
    • TNFalpha therapy in psoriatic arthritis and psoriasis
    • Mease P. TNFalpha therapy in psoriatic arthritis and psoriasis. Ann Rheum Dis 2004;63:755-8
    • (2004) Ann Rheum Dis , vol.63 , pp. 755-758
    • Mease, P.1
  • 58
    • 34548263277 scopus 로고    scopus 로고
    • Radiographic progression in patients with ankylosing spondylitis after 4 yrs of treatment with the anti-TNF-alpha antibody infliximab
    • Baraliakos X, Listing J, Brandt J, et al. Radiographic progression in patients with ankylosing spondylitis after 4 yrs of treatment with the anti-TNF-alpha antibody infliximab. Rheumatology (Oxford) 2007;46:1450-3
    • (2007) Rheumatology (Oxford) , vol.46 , pp. 1450-1453
    • Baraliakos, X.1    Listing, J.2    Brandt, J.3
  • 59
    • 0042329252 scopus 로고    scopus 로고
    • Response to infliximab is related to disease duration in paediatric Crohn's disease
    • Lionetti P, Bronzini F, Salvestrini C, et al. Response to infliximab is related to disease duration in paediatric Crohn's disease. Aliment Pharmacol Ther 2003;18:425-31
    • (2003) Aliment Pharmacol Ther , vol.18 , pp. 425-431
    • Lionetti, P.1    Bronzini, F.2    Salvestrini, C.3
  • 60
    • 84873720197 scopus 로고    scopus 로고
    • Subgroup analysis of the placebocontrolled CHARM trial: Increased remission rates through 3 years for adalimumab-treated patients with early Crohn's disease
    • Schreiber S, Reinisch W, Colombel JF, et al. Subgroup analysis of the placebocontrolled CHARM trial: increased remission rates through 3 years for adalimumab-treated patients with early Crohn's disease. J Crohns Colitis 2013;7:213-21
    • (2013) J Crohns Colitis , vol.7 , pp. 213-221
    • Schreiber, S.1    Reinisch, W.2    Colombel, J.F.3
  • 61
    • 77954423661 scopus 로고    scopus 로고
    • Increased response and remission rates in short-duration Crohn's disease with subcutaneous certolizumab pegol: An analysis of PRECiSE 2 randomized maintenance trial data
    • Schreiber S, Colombel JF, Bloomfield R, et al. Increased response and remission rates in short-duration Crohn's disease with subcutaneous certolizumab pegol: an analysis of PRECiSE 2 randomized maintenance trial data. Am J Gastroenterol 2010;105:1574-82
    • (2010) Am J Gastroenterol , vol.105 , pp. 1574-1582
    • Schreiber, S.1    Colombel, J.F.2    Bloomfield, R.3
  • 62
    • 39449085441 scopus 로고    scopus 로고
    • Early combined immunosuppression or conventional management in patients with newly diagnosed Crohn's disease: An open randomised trial
    • D'Haens G, Baert F, van Assche G, et al. Early combined immunosuppression or conventional management in patients with newly diagnosed Crohn's disease: an open randomised trial. Lancet 2008;371:660-7
    • (2008) Lancet , vol.371 , pp. 660-667
    • D'haens, G.1    Baert, F.2    Van Assche, G.3
  • 63
    • 84872092353 scopus 로고    scopus 로고
    • Clinical risk factors for complicated disease: How reliable are they?
    • Zallot C, Peyrin-Biroulet L. Clinical risk factors for complicated disease: how reliable are they? Dig Dis 2012;30(Suppl 3):67-72
    • (2012) Dig Dis , vol.30 , Issue.SUPPL. 3 , pp. 67-72
    • Zallot, C.1    Peyrin-Biroulet, L.2
  • 64
    • 69249152654 scopus 로고    scopus 로고
    • Genetic risk profiling and prediction of disease course in Crohn's disease patients
    • e2
    • Henckaerts L, Van Steen K, Verstreken I, et al. Genetic risk profiling and prediction of disease course in Crohn's disease patients. Clin Gastroenterol Hepatol 2009;7:972-80; e2
    • (2009) Clin Gastroenterol Hepatol , vol.7 , pp. 972-980
    • Henckaerts, L.1    Van Steen, K.2    Verstreken, I.3
  • 65
    • 34948854194 scopus 로고    scopus 로고
    • New serological markers in inflammatory bowel disease are associated with complicated disease behaviour
    • Ferrante M, Henckaerts L, Joossens M, et al. New serological markers in inflammatory bowel disease are associated with complicated disease behaviour. Gut 2007;56:1394-403
    • (2007) Gut , vol.56 , pp. 1394-1403
    • Ferrante, M.1    Henckaerts, L.2    Joossens, M.3
  • 66
    • 75149161836 scopus 로고    scopus 로고
    • The second European evidencebased Consensus on the diagnosis and management of Crohn's disease: Current management
    • Dignass A, Van Assche G, Lindsay JO, et al. The second European evidencebased Consensus on the diagnosis and management of Crohn's disease: current management. J Crohns Colitis 2010;4:28-62
    • (2010) J Crohns Colitis , vol.4 , pp. 28-62
    • Dignass, A.1    Van Assche, G.2    Lindsay, J.O.3
  • 67
    • 84855161776 scopus 로고    scopus 로고
    • Switch to adalimumab in patients with Crohn's disease controlled by maintenance infliximab: Prospective randomised SWITCH trial
    • Van Assche G, Vermeire S, Ballet V, et al. Switch to adalimumab in patients with Crohn's disease controlled by maintenance infliximab: prospective randomised SWITCH trial. Gut 2012;61:229-34
    • (2012) Gut , vol.61 , pp. 229-234
    • Van Assche, G.1    Vermeire, S.2    Ballet, V.3
  • 68
    • 33750485302 scopus 로고    scopus 로고
    • Risk and prevention of tuberculosis and other serious opportunistic infections associated with the inhibition of tumor necrosis factor
    • Winthrop KL. Risk and prevention of tuberculosis and other serious opportunistic infections associated with the inhibition of tumor necrosis factor. Nat Clin Pract Rheumatol 2006;2:602-10
    • (2006) Nat Clin Pract Rheumatol , vol.2 , pp. 602-610
    • Winthrop, K.L.1
  • 69
    • 78650239266 scopus 로고    scopus 로고
    • A systematic review of factors that contribute to hepatosplenic T-Cell lymphoma in patients with inflammatory bowel disease
    • e1
    • Kotlyar DS, Osterman MT, Diamond RH, et al. A systematic review of factors that contribute to hepatosplenic T-Cell lymphoma in patients with inflammatory bowel disease. Clin Gastroenterol Hepatol 2011;9:36-41; e1
    • (2011) Clin Gastroenterol Hepatol , vol.9 , pp. 36-41
    • Kotlyar, D.S.1    Osterman, M.T.2    Diamond, R.H.3
  • 70
    • 77953103015 scopus 로고    scopus 로고
    • Influence of anti-tumor necrosis factor therapy on cancer incidence in patients with rheumatoid arthritis who have had a prior malignancy: Results from the British Society for Rheumatology Biologics Register
    • Dixon WG, Watson KD, Lunt M, et al. Influence of anti-tumor necrosis factor therapy on cancer incidence in patients with rheumatoid arthritis who have had a prior malignancy: results from the British Society for Rheumatology Biologics Register. Arthritis Care Res (Hoboken) 2010;62:755-63
    • (2010) Arthritis Care Res (Hoboken) , vol.62 , pp. 755-763
    • Dixon, W.G.1    Watson, K.D.2    Lunt, M.3
  • 71
    • 84857801058 scopus 로고    scopus 로고
    • Inflammatory bowel disease therapies and cancer risk: Where are we and where are we going?
    • Beaugerie L. Inflammatory bowel disease therapies and cancer risk: where are we and where are we going? Gut 2012;61:476-83
    • (2012) Gut , vol.61 , pp. 476-483
    • Beaugerie, L.1
  • 72
    • 84885618122 scopus 로고    scopus 로고
    • The management of immunosuppression in patients with inflammatory bowel disease and cancer
    • Bernheim O, Colombel JF, Ullman TA, et al. The management of immunosuppression in patients with inflammatory bowel disease and cancer. Gut 2013;62:1523-8
    • (2013) Gut , vol.62 , pp. 1523-1528
    • Bernheim, O.1    Colombel, J.F.2    Ullman, T.A.3
  • 73
    • 0038755661 scopus 로고    scopus 로고
    • Randomized, double-blind, placebocontrolled, pilot trial of infliximab, a chimeric monoclonal antibody to tumor necrosis factor-alpha, in patients with moderate-to-severe heart failure: Results of the anti-TNF Therapy Against Congestive Heart Failure (ATTACH) trial
    • Chung ES, Packer M, Lo KH, et al. Randomized, double-blind, placebocontrolled, pilot trial of infliximab, a chimeric monoclonal antibody to tumor necrosis factor-alpha, in patients with moderate-to-severe heart failure: results of the anti-TNF Therapy Against Congestive Heart Failure (ATTACH) trial. Circulation 2003;107:3133-40
    • (2003) Circulation , vol.107 , pp. 3133-3140
    • Chung, E.S.1    Packer, M.2    Lo, K.H.3
  • 74
    • 65249085647 scopus 로고    scopus 로고
    • Long-term course of demyelinating neuropathies occurring during tumor necrosis factor-alpha-blocker therapy
    • Lozeron P, Denier C, Lacroix C, Adams D. Long-term course of demyelinating neuropathies occurring during tumor necrosis factor-alpha-blocker therapy. Arch Neurol 2009;66:490-7
    • (2009) Arch Neurol , vol.66 , pp. 490-497
    • Lozeron, P.1    Denier, C.2    Lacroix, C.3    Adams, D.4
  • 75
    • 79958294127 scopus 로고    scopus 로고
    • Infliximab, azathioprine, or infliximab + azathioprine for treatment of moderate to severe ulcerative colitis: The UC SUCCESS trial
    • Panaccione R, Ghosh S, Middleton S, et al. Infliximab, azathioprine, or infliximab + azathioprine for treatment of moderate to severe ulcerative colitis: the UC SUCCESS trial. J Crohn's Colitis 2011;5:S8
    • (2011) J Crohn's Colitis , vol.5
    • Panaccione, R.1    Ghosh, S.2    Middleton, S.3
  • 76
    • 0034735842 scopus 로고    scopus 로고
    • Infliximab and methotrexate in the treatment of rheumatoid arthritis Anti-Tumor Necrosis Factor Trial in Rheumatoid Arthritis with Concomitant Therapy Study Group
    • Lipsky PE, van der Heijde DM, St Clair EW, et al. Infliximab and methotrexate in the treatment of rheumatoid arthritis. Anti-Tumor Necrosis Factor Trial in Rheumatoid Arthritis with Concomitant Therapy Study Group. N Engl J Med 2000;343:1594-602
    • (2000) N Engl J Med , vol.343 , pp. 1594-1602
    • Lipsky, P.E.1    Van Der Heijde, D.M.2    St Clair, E.W.3
  • 77
    • 44649090092 scopus 로고    scopus 로고
    • Withdrawal of immunosuppression in Crohn's disease treated with scheduled infliximab maintenance: A randomized trial
    • Van Assche G, Magdelaine-Beuzelin C, D'Haens G, et al. Withdrawal of immunosuppression in Crohn's disease treated with scheduled infliximab maintenance: a randomized trial. Gastroenterology 2008;134:1861-8
    • (2008) Gastroenterology , vol.134 , pp. 1861-1868
    • Van Assche, G.1    Magdelaine-Beuzelin, C.2    D'haens, G.3
  • 78
    • 46749098893 scopus 로고    scopus 로고
    • Long term follow-up of a cohort of steroid-dependent Crohn's disease patients included in a randomized trial evaluating short term infliximab combined with azathioprine
    • Costes L, Colombel J-F, Mary J-Y, et al. Long term follow-up of a cohort of steroid-dependent Crohn's disease patients included in a randomized trial evaluating short term infliximab combined with azathioprine. Gastroenterology 2008;134:A-134
    • (2008) Gastroenterology , vol.134
    • Costes, L.1    Colombel, J.-F.2    Mary, J.-Y.3
  • 79
    • 80053130162 scopus 로고    scopus 로고
    • Results of the 2nd part Scientific Workshop of the ECCO. II: Measures and markers of prediction to achieve, detect, and monitor intestinal healing in inflammatory bowel disease
    • Daperno M, Castiglione F, de Ridder L, et al. Results of the 2nd part Scientific Workshop of the ECCO. II: measures and markers of prediction to achieve, detect, and monitor intestinal healing in inflammatory bowel disease. J Crohns Colitis 2011;5:484-98
    • (2011) J Crohns Colitis , vol.5 , pp. 484-498
    • Daperno, M.1    Castiglione, F.2    De Ridder, L.3
  • 80
    • 83555174925 scopus 로고    scopus 로고
    • Recommendations for the treatment of Crohn's disease with tumor necrosis factor antagonists: An expert consensus report
    • Feagan BG, Lemann M, Befrits R, et al. Recommendations for the treatment of Crohn's disease with tumor necrosis factor antagonists: an expert consensus report. Inflamm Bowel Dis 2012;18:152-60
    • (2012) Inflamm Bowel Dis , vol.18 , pp. 152-160
    • Feagan, B.G.1    Lemann, M.2    Befrits, R.3
  • 81
    • 0001607738 scopus 로고
    • Development and validation of an endoscopic index of the severity for Crohn's disease: A prospective multicentre study Groupe d'Etudes Therapeutiques des Affections Inflammatoires du Tube Digestif (GETAID)
    • Mary JY, Modigliani R. Development and validation of an endoscopic index of the severity for Crohn's disease: a prospective multicentre study. Groupe d'Etudes Therapeutiques des Affections Inflammatoires du Tube Digestif (GETAID). Gut 1989;30:983-9
    • (1989) Gut , vol.30 , pp. 983-989
    • Mary, J.Y.1    Modigliani, R.2
  • 82
    • 4744375545 scopus 로고    scopus 로고
    • Development and validation of a new, simplified endoscopic activity score for Crohn's disease: The SES-CD
    • Daperno M, D'Haens G, Van Assche G, et al. Development and validation of a new, simplified endoscopic activity score for Crohn's disease: the SES-CD. Gastrointest Endosc 2004;60:505-12
    • (2004) Gastrointest Endosc , vol.60 , pp. 505-512
    • Daperno, M.1    D'haens, G.2    Van Assche, G.3
  • 83
    • 0025013473 scopus 로고
    • Predictability of the postoperative course of Crohn's disease
    • Rutgeerts P, Geboes K, Vantrappen G, et al. Predictability of the postoperative course of Crohn's disease. Gastroenterology 1990;99:956-63
    • (1990) Gastroenterology , vol.99 , pp. 956-963
    • Rutgeerts, P.1    Geboes, K.2    Vantrappen, G.3
  • 84
    • 84862777782 scopus 로고    scopus 로고
    • Adalimumab induces and maintains mucosal healing in patients with Crohn's disease: Data from the EXTEND trial
    • e2
    • Rutgeerts P, Van Assche G, Sandborn WJ, et al. Adalimumab induces and maintains mucosal healing in patients with Crohn's disease: data from the EXTEND trial. Gastroenterology 2012;142:1102-11; e2
    • (2012) Gastroenterology , vol.142 , pp. 1102-1111
    • Rutgeerts, P.1    Van Assche, G.2    Sandborn, W.J.3
  • 85
    • 32944461717 scopus 로고    scopus 로고
    • Scheduled maintenance treatment with infliximab is superior to episodic treatment for the healing of mucosal ulceration associated with Crohn's disease
    • Rutgeerts P, Diamond RH, Bala M, et al. Scheduled maintenance treatment with infliximab is superior to episodic treatment for the healing of mucosal ulceration associated with Crohn's disease. Gastrointest Endosc 2006;63:433-42
    • (2006) Gastrointest Endosc , vol.63 , pp. 433-442
    • Rutgeerts, P.1    Diamond, R.H.2    Bala, M.3
  • 86
    • 84872075826 scopus 로고    scopus 로고
    • Endoscopic improvement of mucosal lesions in patients with moderate to severe ileocolonic Crohn's disease following treatment with certolizumab pegol
    • Hebuterne X, Lemann M, Bouhnik Y, et al. Endoscopic improvement of mucosal lesions in patients with moderate to severe ileocolonic Crohn's disease following treatment with certolizumab pegol. Gut 2013;62:201-8
    • (2013) Gut , vol.62 , pp. 201-208
    • Hebuterne, X.1    Lemann, M.2    Bouhnik, Y.3
  • 87
    • 75449114677 scopus 로고    scopus 로고
    • Mucosal healing predicts sustained clinical remission in patients with earlystage Crohn's disease
    • Baert F, Moortgat L, Van Assche G, et al. Mucosal healing predicts sustained clinical remission in patients with earlystage Crohn's disease. Gastroenterology 2010;138:463-8
    • (2010) Gastroenterology , vol.138 , pp. 463-468
    • Baert, F.1    Moortgat, L.2    Van Assche, G.3
  • 88
    • 0023521441 scopus 로고
    • Coated oral 5-aminosalicylic acid therapy for mildly to moderately active ulcerative colitis A randomized study
    • Schroeder KW, Tremaine WJ, Ilstrup DM. Coated oral 5-aminosalicylic acid therapy for mildly to moderately active ulcerative colitis. A randomized study. N Engl J Med 1987;317:1625-9
    • (1987) N Engl J Med , vol.317 , pp. 1625-1629
    • Schroeder, K.W.1    Tremaine, W.J.2    Ilstrup, D.M.3
  • 89
    • 34547503869 scopus 로고    scopus 로고
    • Mucosal healing in inflammatory bowel disease: Results from a Norwegian population-based cohort
    • Froslie KF, Jahnsen J, Moum BA, Vatn MH. Mucosal healing in inflammatory bowel disease: results from a Norwegian population-based cohort. Gastroenterology 2007;133:412-22
    • (2007) Gastroenterology , vol.133 , pp. 412-422
    • Froslie, K.F.1    Jahnsen, J.2    Moum, B.A.3    Vatn, M.H.4
  • 90
    • 79957452795 scopus 로고    scopus 로고
    • Mucosal healing predicts late outcomes after the first course of corticosteroids for newly diagnosed ulcerative colitis
    • e3
    • Ardizzone S, Cassinotti A, Duca P, et al. Mucosal healing predicts late outcomes after the first course of corticosteroids for newly diagnosed ulcerative colitis. Clin Gastroenterol Hepatol 2011;9:483-9; e3
    • (2011) Clin Gastroenterol Hepatol , vol.9 , pp. 483-489
    • Ardizzone, S.1    Cassinotti, A.2    Duca, P.3
  • 91
    • 32944461717 scopus 로고    scopus 로고
    • Scheduled maintenance treatment with infliximab is superior to episodic treatment for the healing of mucosal ulceration associated with Crohn's disease
    • Rutgeerts P, Diamond RH, Bala M, et al. Scheduled maintenance treatment with infliximab is superior to episodic treatment for the healing of mucosal ulceration associated with Crohn's disease. Gastrointest Endosc 2006;63:433-42
    • (2006) Gastrointest Endosc , vol.63 , pp. 433-442
    • Rutgeerts, P.1    Diamond, R.H.2    Bala, M.3
  • 92
    • 70350172248 scopus 로고    scopus 로고
    • Mucosal healing predicts long-term outcome of maintenance therapy with infliximab in Crohn's disease
    • Schnitzler F, Fidder H, Ferrante M, et al. Mucosal healing predicts long-term outcome of maintenance therapy with infliximab in Crohn's disease. Inflamm Bowel Dis 2009;15:1295-301
    • (2009) Inflamm Bowel Dis , vol.15 , pp. 1295-1301
    • Schnitzler, F.1    Fidder, H.2    Ferrante, M.3
  • 93
    • 80053130407 scopus 로고    scopus 로고
    • Early mucosal healing with infliximab is associated with improved long-term clinical outcomes in ulcerative colitis
    • Colombel JF, Rutgeerts P, Reinisch W, et al. Early mucosal healing with infliximab is associated with improved long-term clinical outcomes in ulcerative colitis. Gastroenterology 2011;141:1194-201
    • (2011) Gastroenterology , vol.141 , pp. 1194-1201
    • Colombel, J.F.1    Rutgeerts, P.2    Reinisch, W.3
  • 94
    • 77957226063 scopus 로고    scopus 로고
    • Clinical trial: Colectomy after rescue therapy in ulcerative colitis - 3-year follow-up of the Swedish-Danish controlled infliximab study
    • Gustavsson A, Jarnerot G, Hertervig E, et al. Clinical trial: colectomy after rescue therapy in ulcerative colitis - 3-year follow-up of the Swedish-Danish controlled infliximab study. Aliment Pharmacol Ther 2010;32:984-9
    • (2010) Aliment Pharmacol Ther , vol.32 , pp. 984-989
    • Gustavsson, A.1    Jarnerot, G.2    Hertervig, E.3
  • 95
    • 33645994506 scopus 로고    scopus 로고
    • Thirty-year analysis of a colonoscopic surveillance program for neoplasia in ulcerative colitis
    • Rutter MD, Saunders BP, Wilkinson KH, et al. Thirty-year analysis of a colonoscopic surveillance program for neoplasia in ulcerative colitis. Gastroenterology 2006;130:1030-8
    • (2006) Gastroenterology , vol.130 , pp. 1030-1038
    • Rutter, M.D.1    Saunders, B.P.2    Wilkinson, K.H.3
  • 96
    • 33748095236 scopus 로고    scopus 로고
    • Increased inflammatory activity is an independent risk factor for dysplasia and colorectal cancer in ulcerative colitis: A case-control analysiswith blinded prospective pathology review
    • Rubin D, Hire D, Rothe J, et al. Increased inflammatory activity is an independent risk factor for dysplasia and colorectal cancer in ulcerative colitis: a case-control analysiswith blinded prospective pathology review. Gastroenterology 2006;130:A2
    • (2006) Gastroenterology , vol.130
    • Rubin, D.1    Hire, D.2    Rothe, J.3
  • 97
    • 34848893583 scopus 로고    scopus 로고
    • Histologic inflammation is a risk factor for progression to colorectal neoplasia in ulcerative colitis: A cohort study
    • Gupta RB, Harpaz N, Itzkowitz S, et al. Histologic inflammation is a risk factor for progression to colorectal neoplasia in ulcerative colitis: a cohort study. Gastroenterology 2007;133:1099-105
    • (2007) Gastroenterology , vol.133 , pp. 1099-1105
    • Gupta, R.B.1    Harpaz, N.2    Itzkowitz, S.3
  • 98
    • 83955162272 scopus 로고    scopus 로고
    • Maintenance of remission among patients with Crohn's disease on antimetabolite therapy after infliximab therapy is stopped
    • e5
    • Louis E, Mary JY, Vernier-Massouille G, et al. Maintenance of remission among patients with Crohn's disease on antimetabolite therapy after infliximab therapy is stopped. Gastroenterology 2012;142:63-70; e5
    • (2012) Gastroenterology , vol.142 , pp. 63-70
    • Louis, E.1    Mary, J.Y.2    Vernier-Massouille, G.3
  • 99
    • 63849101007 scopus 로고    scopus 로고
    • Long-term outcome of treatment with infliximab in 614 patients with Crohn's disease: Results from a singlecentre cohort
    • Schnitzler F, Fidder H, Ferrante M, et al. Long-term outcome of treatment with infliximab in 614 patients with Crohn's disease: results from a singlecentre cohort. Gut 2009;58:492-500
    • (2009) Gut , vol.58 , pp. 492-500
    • Schnitzler, F.1    Fidder, H.2    Ferrante, M.3
  • 100
    • 78649465120 scopus 로고    scopus 로고
    • Maintenance of clinical benefit in Crohn's disease patients after discontinuation of infliximab: Long-term follow-up of a single centre cohort
    • Waugh AW, Garg S, Matic K, et al. Maintenance of clinical benefit in Crohn's disease patients after discontinuation of infliximab: long-term follow-up of a single centre cohort. Aliment Pharmacol Ther 2010;32:1129-34
    • (2010) Aliment Pharmacol Ther , vol.32 , pp. 1129-1134
    • Waugh, A.W.1    Garg, S.2    Matic, K.3
  • 101
    • 84884138341 scopus 로고    scopus 로고
    • When do we dare to stop biological or immunomodulatory therapy for Crohn's disease? Results of a multidisciplinary European expert panel
    • published online 9 May 2013; doi:10.1016/j. crohns.2013.04.013
    • Pittet V, Froehlich F, Maillard MH, et al. When do we dare to stop biological or immunomodulatory therapy for Crohn's disease? Results of a multidisciplinary European expert panel. J Crohns Colitis 2013;published online 9 May 2013; doi:10.1016/j. crohns.2013.04.013
    • (2013) J Crohns Colitis
    • Pittet, V.1    Froehlich, F.2    Maillard, M.H.3
  • 102
    • 79953788656 scopus 로고    scopus 로고
    • Assessing response and loss of response to biological therapies in IBD
    • Yanai H, Hanauer SB. Assessing response and loss of response to biological therapies in IBD. Am J Gastroenterol 2011;106:685-98
    • (2011) Am J Gastroenterol , vol.106 , pp. 685-698
    • Yanai, H.1    Hanauer, S.B.2
  • 103
    • 77953440013 scopus 로고    scopus 로고
    • Predicting response to Anti-TNF Agents for the treatment of crohn's disease
    • Siegel CA, Melmed GY. Predicting response to Anti-TNF Agents for the treatment of crohn's disease. Ther Adv Gastroenterol 2009;2:245-51
    • (2009) Ther Adv Gastroenterol , vol.2 , pp. 245-251
    • Siegel, C.A.1    Melmed, G.Y.2
  • 104
    • 77953510743 scopus 로고    scopus 로고
    • Role of genetics in prediction of disease course and response to therapy
    • Vermeire S, Van Assche G, Rutgeerts P. Role of genetics in prediction of disease course and response to therapy. World J Gastroenterol 2010;16:2609-15
    • (2010) World J Gastroenterol , vol.16 , pp. 2609-2615
    • Vermeire, S.1    Van Assche, G.2    Rutgeerts, P.3
  • 105
    • 71049134874 scopus 로고    scopus 로고
    • Mucosal gene expression of antimicrobial peptides in inflammatory bowel disease before and after first infliximab treatment
    • Arijs I, De Hertogh G, Lemaire K, et al. Mucosal gene expression of antimicrobial peptides in inflammatory bowel disease before and after first infliximab treatment. PLoS One 2009;4:e7984
    • (2009) PLoS One , vol.4
    • Arijs, I.1    De Hertogh, G.2    Lemaire, K.3
  • 106
    • 38149077059 scopus 로고    scopus 로고
    • The use of adalimumab in the management of refractory Crohn's disease
    • Ho GT, Smith L, Aitken S, et al. The use of adalimumab in the management of refractory Crohn's disease. Aliment Pharmacol Ther 2008;27:308-15
    • (2008) Aliment Pharmacol Ther , vol.27 , pp. 308-315
    • Ho, G.T.1    Smith, L.2    Aitken, S.3
  • 107
    • 71449114736 scopus 로고    scopus 로고
    • The efficacy and safety of a third anti-TNF monoclonal antibody in Crohn's disease after failure of two other anti-TNF antibodies
    • Allez M, Vermeire S, Mozziconacci N, et al. The efficacy and safety of a third anti-TNF monoclonal antibody in Crohn's disease after failure of two other anti-TNF antibodies. Aliment Pharmacol Ther 2010;31:92-101
    • (2010) Aliment Pharmacol Ther , vol.31 , pp. 92-101
    • Allez, M.1    Vermeire, S.2    Mozziconacci, N.3
  • 108
    • 83555163744 scopus 로고    scopus 로고
    • Adalimumab produces clinical remission and reduces extraintestinal manifestations in Crohn's disease: Results from CARE
    • Lofberg R, Louis EV, Reinisch W, et al. Adalimumab produces clinical remission and reduces extraintestinal manifestations in Crohn's disease: results from CARE. Inflamm Bowel Dis 2012;18:1-9
    • (2012) Inflamm Bowel Dis , vol.18 , pp. 1-9
    • Lofberg, R.1    Louis, E.V.2    Reinisch, W.3
  • 109
    • 62049083383 scopus 로고    scopus 로고
    • Loss of response and requirement of infliximab dose intensification in Crohn's disease: A review
    • Gisbert JP, Panes J. Loss of response and requirement of infliximab dose intensification in Crohn's disease: a review. Am J Gastroenterol 2009;104:760-7
    • (2009) Am J Gastroenterol , vol.104 , pp. 760-767
    • Gisbert, J.P.1    Panes, J.2
  • 110
    • 79953786419 scopus 로고    scopus 로고
    • Loss of response and need for adalimumab dose intensification in Crohn's disease: A systematic review
    • Billioud V, Sandborn WJ, Peyrin-Biroulet L. Loss of response and need for adalimumab dose intensification in Crohn's disease: a systematic review. Am J Gastroenterol 2011;106:674-84
    • (2011) Am J Gastroenterol , vol.106 , pp. 674-684
    • Billioud, V.1    Sandborn, W.J.2    Peyrin-Biroulet, L.3
  • 111
    • 77952778634 scopus 로고    scopus 로고
    • Serum albumin concentration: A predictive factor of infliximab pharmacokinetics and clinical response in patients with ulcerative colitis
    • Fasanmade AA, Adedokun OJ, Olson A, et al. Serum albumin concentration: a predictive factor of infliximab pharmacokinetics and clinical response in patients with ulcerative colitis. Int J Clin Pharmacol Ther 2010;48:297-308
    • (2010) Int J Clin Pharmacol Ther , vol.48 , pp. 297-308
    • Fasanmade, A.A.1    Adedokun, O.J.2    Olson, A.3
  • 112
    • 79960283949 scopus 로고    scopus 로고
    • Pharmacokinetic properties of infliximab in children and adults with Crohn's disease: A retrospective analysis of data from 2 phase III clinical trials
    • Fasanmade AA, Adedokun OJ, Blank M, et al. Pharmacokinetic properties of infliximab in children and adults with Crohn's disease: a retrospective analysis of data from 2 phase III clinical trials. Clin Ther 2011;33:946-64
    • (2011) Clin Ther , vol.33 , pp. 946-964
    • Fasanmade, A.A.1    Adedokun, O.J.2    Blank, M.3
  • 113
    • 58149132609 scopus 로고    scopus 로고
    • Infliximab pharmacokinetics in inflammatory bowel disease patients
    • Ternant D, Aubourg A, Magdelaine-Beuzelin C, et al. Infliximab pharmacokinetics in inflammatory bowel disease patients. Ther Drug Monit 2008;30:523-9
    • (2008) Ther Drug Monit , vol.30 , pp. 523-529
    • Ternant, D.1    Aubourg, A.2    Magdelaine-Beuzelin, C.3
  • 114
    • 71249099165 scopus 로고    scopus 로고
    • Population pharmacokinetic analysis of infliximab in patients with ulcerative colitis
    • Fasanmade AA, Adedokun OJ, Ford J, et al. Population pharmacokinetic analysis of infliximab in patients with ulcerative colitis. Eur J Clin Pharmacol 2009;65:1211-28
    • (2009) Eur J Clin Pharmacol , vol.65 , pp. 1211-1228
    • Fasanmade, A.A.1    Adedokun, O.J.2    Ford, J.3
  • 115
    • 41849135759 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha binding capacity and anti-infliximab antibodies measured by fluid-phase radioimmunoassays as predictors of clinical efficacy of infliximab in Crohn's disease
    • Ainsworth MA, Bendtzen K, Brynskov J. Tumor necrosis factor-alpha binding capacity and anti-infliximab antibodies measured by fluid-phase radioimmunoassays as predictors of clinical efficacy of infliximab in Crohn's disease. Am J Gastroenterol 2008;103:944-8
    • (2008) Am J Gastroenterol , vol.103 , pp. 944-948
    • Ainsworth, M.A.1    Bendtzen, K.2    Brynskov, J.3
  • 116
    • 84862338286 scopus 로고    scopus 로고
    • Doubling the infliximab dose versus halving the infusion intervals in Crohn's disease patients with loss of response
    • Katz L, Gisbert JP, Manoogian B, et al. Doubling the infliximab dose versus halving the infusion intervals in Crohn's disease patients with loss of response. Inflamm Bowel Dis 2012;18:2026-33
    • (2012) Inflamm Bowel Dis , vol.18 , pp. 2026-2033
    • Katz, L.1    Gisbert, J.P.2    Manoogian, B.3
  • 117
    • 70350130547 scopus 로고    scopus 로고
    • Influence of trough serum levels and immunogenicity on long-term outcome of adalimumab therapy in Crohn's disease
    • Karmiris K, Paintaud G, Noman M, et al. Influence of trough serum levels and immunogenicity on long-term outcome of adalimumab therapy in Crohn's disease. Gastroenterology 2009;137:1628-40
    • (2009) Gastroenterology , vol.137 , pp. 1628-1640
    • Karmiris, K.1    Paintaud, G.2    Noman, M.3
  • 118
    • 77955273592 scopus 로고    scopus 로고
    • Reinduction with certolizumab pegol in patients with relapsed Crohn's disease: Results from the PRECiSE 4 Study
    • e1
    • Sandborn WJ, Schreiber S, Hanauer SB, et al. Reinduction with certolizumab pegol in patients with relapsed Crohn's disease: results from the PRECiSE 4 Study. Clin Gastroenterol Hepatol 2010;8:696-702; e1
    • (2010) Clin Gastroenterol Hepatol , vol.8 , pp. 696-702
    • Sandborn, W.J.1    Schreiber, S.2    Hanauer, S.B.3
  • 119
    • 3042579454 scopus 로고    scopus 로고
    • Incidence and importance of antibody responses to infliximab after maintenance or episodic treatment in Crohn's disease
    • Hanauer SB, Wagner CL, Bala M, et al. Incidence and importance of antibody responses to infliximab after maintenance or episodic treatment in Crohn's disease. Clin Gastroenterol Hepatol 2004;2:542-53
    • (2004) Clin Gastroenterol Hepatol , vol.2 , pp. 542-553
    • Hanauer, S.B.1    Wagner, C.L.2    Bala, M.3
  • 120
    • 0037434552 scopus 로고    scopus 로고
    • Influence of immunogenicity on the long-term efficacy of infliximab in Crohn's disease
    • Baert F, Noman M, Vermeire S, et al. Influence of immunogenicity on the long-term efficacy of infliximab in Crohn's disease. N Engl J Med 2003;348:601-8
    • (2003) N Engl J Med , vol.348 , pp. 601-608
    • Baert, F.1    Noman, M.2    Vermeire, S.3
  • 121
    • 33749432435 scopus 로고    scopus 로고
    • Association of trough serum infliximab to clinical outcome after scheduled maintenance treatment for Crohn's disease
    • Maser EA, Villela R, Silverberg MS, Greenberg GR. Association of trough serum infliximab to clinical outcome after scheduled maintenance treatment for Crohn's disease. Clin Gastroenterol Hepatol 2006;4:1248-54
    • (2006) Clin Gastroenterol Hepatol , vol.4 , pp. 1248-1254
    • Maser, E.A.1    Villela, R.2    Silverberg, M.S.3    Greenberg, G.R.4
  • 122
    • 73449088039 scopus 로고    scopus 로고
    • Trough serum infliximab: A predictive factor of clinical outcome for infliximab treatment in acute ulcerative colitis
    • Seow CH, Newman A, Irwin SP, et al. Trough serum infliximab: a predictive factor of clinical outcome for infliximab treatment in acute ulcerative colitis. Gut 2010;59:49-54
    • (2010) Gut , vol.59 , pp. 49-54
    • Seow, C.H.1    Newman, A.2    Irwin, S.P.3
  • 123
    • 84863575728 scopus 로고    scopus 로고
    • Development and validation of a homogeneous mobility shift assay for the measurement of infliximab and antibodies-to-infliximab levels in patient serum
    • Wang SL, Ohrmund L, Hauenstein S, et al. Development and validation of a homogeneous mobility shift assay for the measurement of infliximab and antibodies-to-infliximab levels in patient serum. J Immunol Methods 2012;382:177-88
    • (2012) J Immunol Methods , vol.382 , pp. 177-188
    • Wang, S.L.1    Ohrmund, L.2    Hauenstein, S.3
  • 124
    • 84866390993 scopus 로고    scopus 로고
    • Detection of infliximab levels and anti-infliximab antibodies: A comparison of three different assays
    • Vande Casteele N, Buurman DJ, Sturkenboom MG, et al. Detection of infliximab levels and anti-infliximab antibodies: a comparison of three different assays. Aliment Pharmacol Ther 2012;36:765-71
    • (2012) Aliment Pharmacol Ther , vol.36 , pp. 765-771
    • Vande Casteele, N.1    Buurman, D.J.2    Sturkenboom, M.G.3
  • 125
    • 84878945732 scopus 로고    scopus 로고
    • Antibody response to infliximab and its impact on pharmacokinetics can be transient
    • Vande Casteele N, Gils A, Singh S, et al. Antibody response to infliximab and its impact on pharmacokinetics can be transient. Am J Gastroenterol 2013;108:962-71
    • (2013) Am J Gastroenterol , vol.108 , pp. 962-971
    • Vande Casteele, N.1    Gils, A.2    Singh, S.3
  • 126
    • 34548130215 scopus 로고    scopus 로고
    • Effectiveness of concomitant immunosuppressive therapy in suppressing the formation of antibodies to infliximab in Crohn's disease
    • Vermeire S, Noman M, Van Assche G, et al. Effectiveness of concomitant immunosuppressive therapy in suppressing the formation of antibodies to infliximab in Crohn's disease. Gut 2007;56:1226-31
    • (2007) Gut , vol.56 , pp. 1226-1231
    • Vermeire, S.1    Noman, M.2    Van Assche, G.3
  • 127
    • 84866394396 scopus 로고    scopus 로고
    • Results on the Optimisation Phase of the Prospective Controlled Trough Level Adapted Infliximab Treatment (TAXIT) Trial
    • Vande Casteele N, Compernolle G, Ballet V, et al. Results on the Optimisation Phase of the Prospective Controlled Trough Level Adapted Infliximab Treatment (TAXIT) Trial. Gastroenterology 2012;142:S211-S2
    • (2012) Gastroenterology , vol.142
    • Vande Casteele, N.1    Compernolle, G.2    Ballet, V.3
  • 128
    • 84862203198 scopus 로고    scopus 로고
    • Trough levels and antibodies to infliximab may not predict response to intensification of infliximab therapy in patients with inflammatory bowel disease
    • Pariente B, Pineton de Chambrun G, Krzysiek R, et al. Trough levels and antibodies to infliximab may not predict response to intensification of infliximab therapy in patients with inflammatory bowel disease. Inflamm Bowel Dis 2012;18:1199-206
    • (2012) Inflamm Bowel Dis , vol.18 , pp. 1199-1206
    • Pariente, B.1    Pineton De Chambrun, G.2    Krzysiek, R.3
  • 129
    • 84875371134 scopus 로고    scopus 로고
    • Addition of an immunomodulator to infliximab therapy eliminates antidrug antibodies in serum and restores clinical response of patients with inflammatory bowel disease
    • Ben-Horin S, Waterman M, Kopylov U, et al. Addition of an immunomodulator to infliximab therapy eliminates antidrug antibodies in serum and restores clinical response of patients with inflammatory bowel disease. Clin Gastroenterol Hepatol 2013;11:444-7
    • (2013) Clin Gastroenterol Hepatol , vol.11 , pp. 444-447
    • Ben-Horin, S.1    Waterman, M.2    Kopylov, U.3
  • 130
    • 84863724798 scopus 로고    scopus 로고
    • A pooled analysis of infections, malignancy, and mortality in infliximab- and immunomodulatortreated adult patients with inflammatory bowel disease
    • Lichtenstein GR, Rutgeerts P, Sandborn WJ, et al. A pooled analysis of infections, malignancy, and mortality in infliximab- and immunomodulatortreated adult patients with inflammatory bowel disease. Am J Gastroenterol 2012;107:1051-63
    • (2012) Am J Gastroenterol , vol.107 , pp. 1051-1063
    • Lichtenstein, G.R.1    Rutgeerts, P.2    Sandborn, W.J.3
  • 131
    • 84866122837 scopus 로고    scopus 로고
    • Serious infection and mortality in patients with Crohn's disease: More than 5 years of follow-up in the TREAT registry
    • Lichtenstein GR, Feagan BG, Cohen RD, et al. Serious infection and mortality in patients with Crohn's disease: more than 5 years of follow-up in the TREAT registry. Am J Gastroenterol 2012;107:1409-22
    • (2012) Am J Gastroenterol , vol.107 , pp. 1409-1422
    • Lichtenstein, G.R.1    Feagan, B.G.2    Cohen, R.D.3
  • 132
    • 63849251824 scopus 로고    scopus 로고
    • Long-term safety of infliximab for the treatment of inflammatory bowel disease: A single-centre cohort study
    • Fidder H, Schnitzler F, Ferrante M, et al. Long-term safety of infliximab for the treatment of inflammatory bowel disease: a single-centre cohort study. Gut 2009;58:501-8
    • (2009) Gut , vol.58 , pp. 501-508
    • Fidder, H.1    Schnitzler, F.2    Ferrante, M.3
  • 133
    • 84874445437 scopus 로고    scopus 로고
    • Adalimumab: Longterm safety in 23 458 patients from global clinical trials in rheumatoid arthritis, juvenile idiopathic arthritis, ankylosing spondylitis, psoriatic arthritis, psoriasis and Crohn's disease
    • Burmester GR, Panaccione R, Gordon KB, et al. Adalimumab: longterm safety in 23 458 patients from global clinical trials in rheumatoid arthritis, juvenile idiopathic arthritis, ankylosing spondylitis, psoriatic arthritis, psoriasis and Crohn's disease. Ann Rheum Dis 2013;72:517-24
    • (2013) Ann Rheum Dis , vol.72 , pp. 517-524
    • Burmester, G.R.1    Panaccione, R.2    Gordon, K.B.3
  • 134
    • 70349707016 scopus 로고    scopus 로고
    • Adalimumab safety in global clinical trials of patients with Crohn's disease
    • Colombel JF, Sandborn WJ, Panaccione R, et al. Adalimumab safety in global clinical trials of patients with Crohn's disease. Inflamm Bowel Dis 2009;15:1308-19
    • (2009) Inflamm Bowel Dis , vol.15 , pp. 1308-1319
    • Colombel, J.F.1    Sandborn, W.J.2    Panaccione, R.3
  • 135
    • 0035846326 scopus 로고    scopus 로고
    • Tuberculosis associated with infliximab, a tumor necrosis factor alpha-neutralizing agent
    • Keane J, Gershon S, Wise RP, et al. Tuberculosis associated with infliximab, a tumor necrosis factor alpha-neutralizing agent. N Engl J Med 2001;345:1098-104
    • (2001) N Engl J Med , vol.345 , pp. 1098-1104
    • Keane, J.1    Gershon, S.2    Wise, R.P.3
  • 136
    • 20744440158 scopus 로고    scopus 로고
    • Effectiveness of recommendations to prevent reactivation of latent tuberculosis infection in patients treated with tumor necrosis factor antagonists
    • Carmona L, Gomez-Reino JJ, Rodriguez-Valverde V, et al. Effectiveness of recommendations to prevent reactivation of latent tuberculosis infection in patients treated with tumor necrosis factor antagonists. Arthritis Rheum 2005;52:1766-72
    • (2005) Arthritis Rheum , vol.52 , pp. 1766-1772
    • Carmona, L.1    Gomez-Reino, J.J.2    Rodriguez-Valverde, V.3
  • 137
    • 84873716914 scopus 로고    scopus 로고
    • Risk of developing tuberculosis under anti-TNF treatment despite latent infection screening
    • Jauregui-Amezaga A, Turon F, Ordas I, et al. Risk of developing tuberculosis under anti-TNF treatment despite latent infection screening. J Crohns Colitis 2013;7:208-12
    • (2013) J Crohns Colitis , vol.7 , pp. 208-212
    • Jauregui-Amezaga, A.1    Turon, F.2    Ordas, I.3
  • 138
    • 22644446331 scopus 로고    scopus 로고
    • Increased risk of lymphoma among inflammatory bowel disease patients treated with azathioprine and 6-mercaptopurine
    • Kandiel A, Fraser AG, Korelitz BI, et al. Increased risk of lymphoma among inflammatory bowel disease patients treated with azathioprine and 6-mercaptopurine. Gut 2005;54:1121-5
    • (2005) Gut , vol.54 , pp. 1121-1125
    • Kandiel, A.1    Fraser, A.G.2    Korelitz, B.I.3
  • 139
    • 80054862378 scopus 로고    scopus 로고
    • Increased risk for nonmelanoma skin cancers in patients who receive thiopurines for inflammatory bowel disease
    • e1-5
    • Peyrin-Biroulet L, Khosrotehrani K, Carrat F, et al. Increased risk for nonmelanoma skin cancers in patients who receive thiopurines for inflammatory bowel disease. Gastroenterology 2011;141:1621-8; e1-5
    • (2011) Gastroenterology , vol.141 , pp. 1621-1628
    • Peyrin-Biroulet, L.1    Khosrotehrani, K.2    Carrat, F.3
  • 140
    • 2442696315 scopus 로고    scopus 로고
    • Infliximab in inflammatory bowel disease: Clinical outcome in a population based cohort from Stockholm County
    • Ljung T, Karlen P, Schmidt D, et al. Infliximab in inflammatory bowel disease: clinical outcome in a population based cohort from Stockholm County. Gut 2004;53:849-53
    • (2004) Gut , vol.53 , pp. 849-853
    • Ljung, T.1    Karlen, P.2    Schmidt, D.3
  • 141
    • 35349027343 scopus 로고    scopus 로고
    • Lymphoma risk in inflammatory bowel disease: Is it the disease or its treatment?
    • Jones JL, Loftus EV Jr. Lymphoma risk in inflammatory bowel disease: is it the disease or its treatment? Inflamm Bowel Dis 2007;13:1299-307
    • (2007) Inflamm Bowel Dis , vol.13 , pp. 1299-1307
    • Jones, J.L.1    Loftus Jr., E.V.2
  • 142
    • 84864225717 scopus 로고    scopus 로고
    • Risk of melanoma and nonmelanoma skin cancer among patients with inflammatory bowel disease
    • e1
    • Long MD, Martin CF, Pipkin CA, et al. Risk of melanoma and nonmelanoma skin cancer among patients with inflammatory bowel disease. Gastroenterology 2012;143:390-9; e1
    • (2012) Gastroenterology , vol.143 , pp. 390-399
    • Long, M.D.1    Martin, C.F.2    Pipkin, C.A.3
  • 143
    • 67949112671 scopus 로고    scopus 로고
    • Risk of lymphoma associated with combination anti-tumor necrosis factor and immunomodulator therapy for the treatment of Crohn's disease: A meta-analysis
    • Siegel CA, Marden SM, Persing SM, et al. Risk of lymphoma associated with combination anti-tumor necrosis factor and immunomodulator therapy for the treatment of Crohn's disease: a meta-analysis. Clin Gastroenterol Hepatol 2009;7:874-81
    • (2009) Clin Gastroenterol Hepatol , vol.7 , pp. 874-881
    • Siegel, C.A.1    Marden, S.M.2    Persing, S.M.3
  • 144
    • 44649187924 scopus 로고    scopus 로고
    • Efficacy and safety of tumor necrosis factor antagonists in Crohn's disease: Meta-analysis of placebocontrolled trials
    • Peyrin-Biroulet L, Deltenre P, de Suray N, et al. Efficacy and safety of tumor necrosis factor antagonists in Crohn's disease: meta-analysis of placebocontrolled trials. Clin Gastroenterol Hepatol 2008;6:644-53
    • (2008) Clin Gastroenterol Hepatol , vol.6 , pp. 644-653
    • Peyrin-Biroulet, L.1    Deltenre, P.2    De Suray, N.3
  • 145
    • 58149098406 scopus 로고    scopus 로고
    • The safety profile of anti-tumour necrosis factor therapy in inflammatory bowel disease in clinical practice: Analysis of 620 patient-years follow-up
    • Lees CW, Ali AI, Thompson AI, et al. The safety profile of anti-tumour necrosis factor therapy in inflammatory bowel disease in clinical practice: analysis of 620 patient-years follow-up. Aliment Pharmacol Ther 2009;29:286-97
    • (2009) Aliment Pharmacol Ther , vol.29 , pp. 286-297
    • Lees, C.W.1    Ali, A.I.2    Thompson, A.I.3
  • 146
    • 0038649858 scopus 로고    scopus 로고
    • The incidence and management of infusion reactions to infliximab: A large center experience
    • Cheifetz A, Smedley M, Martin S, et al. The incidence and management of infusion reactions to infliximab: a large center experience. Am J Gastroenterol 2003;98:1315-24
    • (2003) Am J Gastroenterol , vol.98 , pp. 1315-1324
    • Cheifetz, A.1    Smedley, M.2    Martin, S.3
  • 147
    • 0038109994 scopus 로고    scopus 로고
    • Autoimmunity associated with antitumor necrosis factor alpha treatment in Crohn's disease: A prospective cohort study
    • Vermeire S, Noman M, Van Assche G, et al. Autoimmunity associated with antitumor necrosis factor alpha treatment in Crohn's disease: A prospective cohort study. Gastroenterology 2003;125:32-39
    • (2003) Gastroenterology , vol.125 , pp. 32-39
    • Vermeire, S.1    Noman, M.2    Van Assche, G.3
  • 148
    • 78650162670 scopus 로고    scopus 로고
    • Formation of antinuclear and double-strand DNA antibodies and frequency of lupus-like syndrome in anti-TNF-alpha antibody-treated patients with inflammatory bowel disease
    • Beigel F, Schnitzler F, Paul Laubender R, et al. Formation of antinuclear and double-strand DNA antibodies and frequency of lupus-like syndrome in anti-TNF-alpha antibody-treated patients with inflammatory bowel disease. Inflamm Bowel Dis 2011;17:91-8
    • (2011) Inflamm Bowel Dis , vol.17 , pp. 91-98
    • Beigel, F.1    Schnitzler, F.2    Paul Laubender, R.3
  • 149
    • 84865732639 scopus 로고    scopus 로고
    • Paradoxical inflammation induced by anti-TNF agents in patients with IBD
    • Cleynen I, Vermeire S. Paradoxical inflammation induced by anti-TNF agents in patients with IBD. Nat Rev Gastroenterol Hepatol 2012;9:496-503
    • (2012) Nat Rev Gastroenterol Hepatol , vol.9 , pp. 496-503
    • Cleynen, I.1    Vermeire, S.2
  • 150
    • 81355151359 scopus 로고    scopus 로고
    • Psoriasis associated with anti-tumour necrosis factor therapy in inflammatory bowel disease: A new series and a review of 120 cases from the literature
    • Cullen G, Kroshinsky D, Cheifetz AS, Korzenik JR. Psoriasis associated with anti-tumour necrosis factor therapy in inflammatory bowel disease: a new series and a review of 120 cases from the literature. Aliment Pharmacol Ther 2011;34:1318-27
    • (2011) Aliment Pharmacol Ther , vol.34 , pp. 1318-1327
    • Cullen, G.1    Kroshinsky, D.2    Cheifetz, A.S.3    Korzenik, J.R.4
  • 151
    • 23744512919 scopus 로고    scopus 로고
    • Inflammatory bowel disease and preterm delivery
    • Elbaz G, Fich A, Levy A, et al. Inflammatory bowel disease and preterm delivery. Int J Gynaecol Obstet 2005;90:193-7
    • (2005) Int J Gynaecol Obstet , vol.90 , pp. 193-197
    • Elbaz, G.1    Fich, A.2    Levy, A.3
  • 152
    • 84864626191 scopus 로고    scopus 로고
    • Management of inflammatory bowel disease in pregnancy
    • Vermeire S, Carbonnel F, Coulie PG, et al. Management of inflammatory bowel disease in pregnancy. J Crohns Colitis 2012;6:811-23
    • (2012) J Crohns Colitis , vol.6 , pp. 811-823
    • Vermeire, S.1    Carbonnel, F.2    Coulie, P.G.3
  • 153
    • 79751472857 scopus 로고    scopus 로고
    • The London Position Statement of the World Congress of Gastroenterology on Biological Therapy for IBD with the European Crohn's and Colitis Organisation: Pregnancy and pediatrics
    • Mahadevan U, Cucchiara S, Hyams JS, et al. The London Position Statement of the World Congress of Gastroenterology on Biological Therapy for IBD with the European Crohn's and Colitis Organisation: pregnancy and pediatrics. Am J Gastroenterol 2011;106:214-23
    • (2011) Am J Gastroenterol , vol.106 , pp. 214-223
    • Mahadevan, U.1    Cucchiara, S.2    Hyams, J.S.3
  • 154
    • 60749119300 scopus 로고    scopus 로고
    • Placental transport of immunoglobulins: A clinical review for gastroenterologists who prescribe therapeutic monoclonal antibodies to women during conception and pregnancy
    • Kane SV, Acquah LA. Placental transport of immunoglobulins: a clinical review for gastroenterologists who prescribe therapeutic monoclonal antibodies to women during conception and pregnancy. Am J Gastroenterol 2009;104:228-33
    • (2009) Am J Gastroenterol , vol.104 , pp. 228-233
    • Kane, S.V.1    Acquah, L.A.2
  • 155
    • 84874576191 scopus 로고    scopus 로고
    • Placental transfer of anti-tumor necrosis factor agents in pregnant patients with inflammatory bowel disease
    • Mahadevan U, Wolf DC, Dubinsky M, et al. Placental transfer of anti-tumor necrosis factor agents in pregnant patients with inflammatory bowel disease. Clin Gastroenterol Hepatol 2013;11:286-92
    • (2013) Clin Gastroenterol Hepatol , vol.11 , pp. 286-292
    • Mahadevan, U.1    Wolf, D.C.2    Dubinsky, M.3
  • 156
    • 65649134752 scopus 로고    scopus 로고
    • A safety assessent of tumor necrosis factor antagonists during pregnancy: A review of the Food and Drug Administration database
    • Carter JD, Ladhani A, Ricca LR, et al. A safety assessent of tumor necrosis factor antagonists during pregnancy: a review of the Food and Drug Administration database. J Rheumatol 2009;36:635-41
    • (2009) J Rheumatol , vol.36 , pp. 635-641
    • Carter, J.D.1    Ladhani, A.2    Ricca, L.R.3
  • 157
    • 84877348798 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha inhibitor therapy and fetal risk: A systematic literature review
    • Marchioni RM, Lichtenstein GR. Tumor necrosis factor-alpha inhibitor therapy and fetal risk: a systematic literature review. World J Gastroenterol 2013;19:2591-602
    • (2013) World J Gastroenterol , vol.19 , pp. 2591-2602
    • Marchioni, R.M.1    Lichtenstein, G.R.2
  • 158
    • 34249824261 scopus 로고    scopus 로고
    • A metaanalysis on the influence of inflammatory bowel disease on pregnancy
    • Cornish J, Tan E, Teare J, et al. A metaanalysis on the influence of inflammatory bowel disease on pregnancy. Gut 2007;56:830-7
    • (2007) Gut , vol.56 , pp. 830-837
    • Cornish, J.1    Tan, E.2    Teare, J.3
  • 159
    • 84865517555 scopus 로고    scopus 로고
    • Infliximab and adalimumab use during breastfeeding
    • Fritzsche J, Pilch A, Mury D, et al. Infliximab and adalimumab use during breastfeeding. J Clin Gastroenterol 2012;46:718-19
    • (2012) J Clin Gastroenterol , vol.46 , pp. 718-719
    • Fritzsche, J.1    Pilch, A.2    Mury, D.3
  • 160
    • 84866755429 scopus 로고    scopus 로고
    • PIANO: A 1000 patient prospective registry of pregnancy outcomes in women with IBD exposed to immunomodulators and biologic therapy
    • Mahadevan U, Martin CF, Sandler RS, et al. PIANO: a 1000 patient prospective registry of pregnancy outcomes in women with IBD exposed to immunomodulators and biologic therapy. Gastroenterology 2012;142(Suppl 1):S149
    • (2012) Gastroenterology , vol.142 , Issue.SUPPL. 1
    • Mahadevan, U.1    Martin, C.F.2    Sandler, R.S.3
  • 161
    • 24144483087 scopus 로고    scopus 로고
    • A randomized, placebo-controlled trial of certolizumab pegol (CDP870) for treatment of Crohn's disease
    • Schreiber S, Rutgeerts P, Fedorak RN, et al. A randomized, placebo-controlled trial of certolizumab pegol (CDP870) for treatment of Crohn's disease. Gastroenterology 2005;129:807-18
    • (2005) Gastroenterology , vol.129 , pp. 807-818
    • Schreiber, S.1    Rutgeerts, P.2    Fedorak, R.N.3
  • 163
    • 84878624235 scopus 로고    scopus 로고
    • ECCO position statement: The use of biosimilar medicines in the treatment of inflammatory bowel disease (IBD)
    • Danese S, Gomollon F. ECCO position statement: the use of biosimilar
    • (2013) J Crohns Colitis , vol.7 , pp. 586-589
    • Danese, S.1    Gomollon, F.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.