Response to infliximab is related to disease duration in paediatric Crohn's disease

Alimentary Pharmacology and Therapeutics

Volumn 18, Issue 4, 2003, Pages 425-431

  Lionetti, P ^a   Bronzini, F ^a   Salvestrini, C ^a   Bascietto, C ^b   Berni Canani, R ^c   De Angelis G L ^d   Guariso, G ^e   Martelossi, S ^f   Papadatou, B ^g   Barabino, A ^h  

^a UNIVERSITY OF FLORENCE   (Italy)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

^c UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^d UNIVERSITY OF PARMA   (Italy)

^e UNIVERSITY OF PADOVA   (Italy)

^f INSTITUTE FOR MATERNAL AND CHILD HEALTH IRCCS BURLO GAROFOLO   (Italy)

^g BAMBINO GESÙ CHILDREN S HOSPITAL   (Italy)

^h G GASLINI INSTITUTE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; AZATHIOPRINE; CORTICOSTEROID; CYCLOSPORIN; DIPHENHYDRAMINE; INFLIXIMAB; MERCAPTOPURINE; MESALAZINE; METHOTREXATE;

ADOLESCENT; ARTICLE; BLINDNESS; CLINICAL ARTICLE; COLON FISTULA; CROHN DISEASE; DISEASE DURATION; DYSPNEA; ENTERIC FEEDING; FEMALE; HEADACHE; HUMAN; HYPOTENSION; MALE; PRESCHOOL CHILD; PRIORITY JOURNAL; RASH; RETROSPECTIVE STUDY; SCHOOL CHILD; SEIZURE; THORAX PAIN; TOTAL PARENTERAL NUTRITION;

ADOLESCENT; ANTIBODIES, MONOCLONAL; CHILD; CHILD, PRESCHOOL; CROHN DISEASE; FEMALE; FOLLOW-UP STUDIES; GASTROINTESTINAL AGENTS; HUMANS; INFUSIONS, INTRAVENOUS; INTESTINAL FISTULA; MALE; RETROSPECTIVE STUDIES; TREATMENT OUTCOME;

EID: 0042329252     PISSN: 02692813     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2036.2003.01672.x     Document Type: Article

References (28)

1. Grand RJ, Ramakrishna J, Calenda KA. Inflammatory bowel disease in the pediatric patient. Gastroenterol Clin North Am 1995; 24: 613-32.
2. Marx G, Seidman EG. Inflammatory bowel disease in pediatric patients. Curr Opin Gastroenterol 1999; 15: 322-5.
3. Seidman EG. Inflammatory bowel disease. In: Roy. C. Silverman, A. Alagille, D. eds. Pediatric Gastrointestinal Disease, 4th edn. St Louis: Mosby, 1996: 586-605.
4. Kirshner BS. Safety of azathioprine and 6-mercaptopurine in pediatric patients with inflammatory bowel disease. Gastroenterology 1998; 115: 813-21.
5. Markowitz J, Grancher K, Kohn N, et al. A multicenter trial of 6-mercaptopurine and prednisone therapy in children with newly diagnosed Crohn's disease. Gastroenterology 2000; 119: 895-902.
6. Van Deventer SJH. Tumour necrosis factor and Crohn's disease. Gut 1997; 40: 443-8.
7. Breese EJ, Michie CA, Nicholls SW, et al. Tumor necrosis factor alpha producing cells in the intestinal mucosa of children with inflammatory bowel disease. Gastroenterology 1994; 106: 1455-66.
8. Braegger CP, Nichols S, Murch SH, et al. Tumour necrosis factor alpha in stool as a marker of intestinal inflammation. Lancet 1992; 339: 89-91.
9. Targan SR, Hanauer SB, van Deventer SJ, et al. A short term study of chimeric monoclonal antibody cA2 to tumor necrosis factor α for Crohn's disease. N Engl J Med 1997; 337: 1029-35.
10. Present DH, Rutgeers P, Targan S, et al. Infliximab for the treatment of fistulas in patients with Crohn's disease. N Engl J Med 1999; 340: 1398-405.
11. Rutgeerts P, D'Haens G, Targan S, et al. Efficacy and safety of retreatment with anti-tumor necrosis factor antibody (infliximab) to maintain remission in Crohn's disease. Gastroenterology 1999; 117: 761-9.
12. Hanauer SB, Feagan BG, Lichtenstein GR, et al. Maintenance infliximab for Crohn's disease: the ACCENT I randomised trial. Lancet 2002; 359: 1541-9.
13. Derkx B, Taminiau J, Radema S, et al. Tumour necrosis factor antibody treatment in Crohn's disease. Lancet 1993; 342: 174-5.
14. Hyams JS, Markowitz J, Wyllie R. Use of infliximab in the treatment of Crohn's disease in children and adolescents. J Pediatr 2000; 137: 192-6.
15. Kugathasan S, Werlin SL, Martinez A, et al. Prolonged duration of response in early but not late pediatric Crohn's disease. Am J Gastroenterol 2000; 95: 3189-94.
16. Crandall WV, Mackner LM. Infusion reactions to infliximab in children and adolescents: frequency, outcome and a predictive model. Aliment Pharmacol Ther 2003; 17: 75-84.
17. Stephens MC, Shepanski MA, Mamula P, et al. Safety and steroid-sparing experience using infliximab for Crohn's disease at a pediatric inflammatory bowel disease center. Am J Gastroenterol 2003; 98: 104-11.
18. Hyams JS, Ferry GD, Mandel FS, et al. Development and validation of a Pediatric Crohn's Disease Activity Index. J Pediatr Gastroenterol Nutr 1991; 12: 439-47.
19. Otley A, Loonen H, Parekh N, et al. Assessing activity of pediatric Crohn's disease: which index to use. Gastroenterology 1999; 116: 527-31.
20. Barabino A, Castellano E, Gandullia P, et al. A girl with severe fistulizing Crohn's disease. Dig Liver Dis 2000; 32: 792-4.
21. Cohen RD, Tsang JF, Hanauer SB. Infliximab in Crohn's disease: first anniversary clinical experience. Am J Gastroenterol 2000; 95: 3469-77.
22. Stephens MC, Shepanski MA, Mamula P, et al. Incidence of infusion reaction in patient receiving infliximab at a pediatric center. J Pediatr Gastroenterol Nutr 2001; 33: 375-6.
23. Kugathasan S, Levy MB, Saeian K, et al. Infliximab retreatment in adults and children with Crohn's disease: risk factors for development of delayed severe systemic reaction. Am J Gastroenterol 2002; 97: 1408-14.
24. Maini R, Breedveld F, Kalden J, et al. Therapeutic efficacy of multiple intravenous infusions of anti-tumor necrosis factor monoclonal antibody combined with low-dose weekly methotrexate in rheumatoid arthritis. Arthritis Rheum 1998; 41: 1552-63.
25. Kugathasan S, Itoh J, Byle JT, et al. Distinct mucosal T cell responses to IL-12 in early and late stage of inflammatory bowel disease. J Pediatr Gastroenterol Nutr 1998; 27: 471.
26. Giannini EH, Brewer EJ, Kuzmina N, et al. Methotrexate in resistant juvenile rheumatoid arthritis. Results of the USA-USSR double-bind, placebo controlled trial. N Engl J Med 1992; 326: 1403-9.
27. Hyams JS. Infliximab treatment of Crohn's disease in children: is time to not go retro(spective). Am J Gastroenterol 2003; 98: 5-6.
28. Griffiths AM, Buller HB. Inflammatory bowel disease. In: Durie, PR, Hamilton, JR, Walker Smith, JA, Watkins, JB, eds. Pediatric Gastrointestinal Disease, 3rd edn. Hamilton: B.C. Decker Inc., 2000; 613-52.