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Volumn 106, Issue 4, 2011, Pages 685-698

Assessing response and loss of response to biological therapies in IBD

Author keywords

[No Author keywords available]

Indexed keywords

ABATACEPT; ADALIMUMAB; AZATHIOPRINE; CERTOLIZUMAB PEGOL; DRUG ANTIBODY; INFLIXIMAB; NATALIZUMAB; RITUXIMAB; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA ANTIBODY;

EID: 79953788656     PISSN: 00029270     EISSN: 15720241     Source Type: Journal    
DOI: 10.1038/ajg.2011.103     Document Type: Review
Times cited : (293)

References (101)
  • 3
    • 34848850085 scopus 로고    scopus 로고
    • Te genetics of infammatory bowel disease
    • Cho JH, Weaver CT. Te genetics of infammatory bowel disease. Gastroenterology 2007;133:1327-39.
    • (2007) Gastroenterology , vol.133 , pp. 1327-39
    • Cho, J.H.1    Weaver, C.T.2
  • 4
    • 34547176642 scopus 로고    scopus 로고
    • Unravelling the pathogenesis of inflammatory bowel disease
    • DOI 10.1038/nature06005, PII NATURE06005
    • Xavier RJ, Podolsky DK. Unravelling the pathogenesis of Infammatory bowel disease. Nature 2007;448:427-34. (Pubitemid 47123518)
    • (2007) Nature , vol.448 , Issue.7152 , pp. 427-434
    • Xavier, R.J.1    Podolsky, D.K.2
  • 5
    • 37849052961 scopus 로고    scopus 로고
    • TNFalpha blockade in human diseases: Mechanisms and future directions
    • Wong M, Ziring D, Korin Y et al. TNFalpha blockade in human diseases: mechanisms and future directions. Clin Immunol 2008;126:121-36.
    • (2008) Clin Immunol , vol.126 , pp. 121-36
    • Wong, M.1    Ziring, D.2    Korin, Y.3
  • 6
    • 0026531017 scopus 로고
    • Tumour necrosis factor alpha in stool as a marker of intestinal infammation
    • Braegger CP, Nicholls S, Murch SH et al Tumour necrosis factor alpha in stool as a marker of intestinal infammation. Lancet 1992;339:89-91.
    • (1992) Lancet , vol.339 , pp. 89-91
    • Braegger, C.P.1    Nicholls, S.2    Murch, S.H.3
  • 7
    • 0025333699 scopus 로고
    • Tumour necrosis factor-alpha and interferon-gamma production measured at the single cell level in normal and inflamed human intestine
    • MacDonald TT, Hutchings P, Choy MY et al. Tumour necrosis factor-alpha and interferon-gamma production measured at the single cell level in normal and infamed human intestine. Clin Exp Immunol 1990;81:301-5. (Pubitemid 20242538)
    • (1990) Clinical and Experimental Immunology , vol.81 , Issue.2 , pp. 301-305
    • MacDonald, T.T.1    Hutchings, P.2    Choy, M.-Y.3    Murch, S.4    Cooke, A.5
  • 11
    • 0030954732 scopus 로고    scopus 로고
    • A short-term study of chimeric monoclonal antibody cA2 to tumor necrosis factor alpha for Crohn's disease. Crohn's Disease cA2 Study Group
    • Targan SR, Hanauer SB, van Deventer SJ et al A short-term study of chimeric monoclonal antibody cA2 to tumor necrosis factor alpha for Crohn's disease. Crohn's Disease cA2 Study Group. N Engl J Med 1997;337:1029-35.
    • (1997) N Engl J Med , vol.337 , pp. 1029-35
    • Targan, S.R.1    Hanauer, S.B.2    Van Deventer, S.J.3
  • 15
    • 67649662356 scopus 로고    scopus 로고
    • Adalimumab for the treat-ment of f stulas in patients with Crohn's disease
    • Colombel JF, Schwartz DA, Sandborn WJ et al Adalimumab for the treat-ment of f stulas in patients with Crohn's disease. Gut 2009; 58: 940-8.
    • (2009) Gut , vol.58 , pp. 940-8
    • Colombel, J.F.1    Schwartz, D.A.2    Sandborn, W.J.3
  • 16
    • 32044451548 scopus 로고    scopus 로고
    • Human anti-tumor necrosis factor monoclonal antibody (adalimumab) in Crohn's disease: The CLASSIC-I trial
    • quiz 591
    • Hanauer SB, Sandborn WJ, Rutgeerts P et al Human anti-tumor necrosis factor monoclonal antibody (adalimumab) in Crohn's disease: the CLASSIC-I trial. Gastroenterology 2006;130:323-33; quiz 591.
    • (2006) Gastroenterology , vol.130 , pp. 323-33
    • Hanauer, S.B.1    Sandborn, W.J.2    Rutgeerts, P.3
  • 17
    • 77953683332 scopus 로고    scopus 로고
    • Continuous therapy with certolizumab pegol maintains remission of patients with Crohn's disease for up to 18 months
    • Lichtenstein GR, Tomsen OO, Schreiber S et al Continuous therapy with certolizumab pegol maintains remission of patients with Crohn's disease for up to 18 months. Clin Gastroenterol Hepatol 2010; 8: 600-9.
    • (2010) Clin Gastroenterol Hepatol , vol.8 , pp. 600-9
    • Lichtenstein, G.R.1    Tomsen, O.O.2    Schreiber, S.3
  • 24
    • 67650137185 scopus 로고    scopus 로고
    • Dealing with immunogenicity of biologicals: Assessment and clinical relevance
    • Wolbink GJ, Aarden LA, Dijkmans BA. Dealing with immunogenicity of biologicals: assessment and clinical relevance. Curr Opin Rheumatol 2009;21:211-5.
    • (2009) Curr Opin Rheumatol , vol.21 , pp. 211-5
    • Wolbink, G.J.1    Aarden, L.A.2    Dijkmans, B.A.3
  • 25
    • 33749432435 scopus 로고    scopus 로고
    • Association of trough serum infiximab to clinical outcome af er scheduled maintenance treatment for Crohn's disease
    • DOI 10.1016/j.cgh.2006.06.025, PII S154235650600677X
    • Maser EA, Villela R, Silverberg MS et al Association of trough serum infiximab to clinical outcome af er scheduled maintenance treatment for Crohn's disease. Clin Gastroenterol Hepatol 2006; 4: 1248-54. (Pubitemid 44512213)
    • (2006) Clinical Gastroenterology and Hepatology , vol.4 , Issue.10 , pp. 1248-1254
    • Maser, E.A.1    Villela, R.2    Silverberg, M.S.3    Greenberg, G.R.4
  • 27
    • 53549083244 scopus 로고    scopus 로고
    • Immunogenicity negatively inf uences the outcome of adalimumab treatment in Crohn's disease
    • West RL, Zelinkova Z, Wolbink GJ et al Immunogenicity negatively inf uences the outcome of adalimumab treatment in Crohn's disease. Aliment Pharmacol Ter 2008;28:1122-6.
    • (2008) Aliment Pharmacol ter , vol.28 , pp. 1122-6
    • West, R.L.1    Zelinkova, Z.2    Wolbink, G.J.3
  • 28
    • 63849251824 scopus 로고    scopus 로고
    • Long-term safety of inf iximab for the treatment of Infammatory bowel disease: A single-centre cohort study
    • Fidder H, Schnitzler F, Ferrante M et al Long-term safety of inf iximab for the treatment of Infammatory bowel disease: a single-centre cohort study Gut 2009;58:501-8.
    • (2009) Gut , vol.58 , pp. 501-8
    • Fidder, H.1    Schnitzler, F.2    Ferrante, M.3
  • 29
    • 33646147141 scopus 로고    scopus 로고
    • Serious infections and mortality in association with therapies for Crohn's disease: TREAT registry
    • Lichtenstein GR, Feagan BG, Cohen RD et al. Serious infections and mortality in association with therapies for Crohn's disease: TREAT registry Clin Gastroenterol Hepatol 2006; 4: 621-30.
    • (2006) Clin Gastroenterol Hepatol , vol.4 , pp. 621-30
    • Lichtenstein, G.R.1    Feagan, B.G.2    Cohen, R.D.3
  • 31
    • 67949112671 scopus 로고    scopus 로고
    • Risk of lymphoma associated with combination anti-tumor necrosis factor and immunomodulator therapy for the treatment of Crohn's disease: A meta-analysis
    • Siegel CA, Marden SM, Persing SM et al Risk of lymphoma associated with combination anti-tumor necrosis factor and immunomodulator therapy for the treatment of Crohn's disease: a meta-analysis. Clin Gastroenterol Hepatol 2009;7:874-81.
    • (2009) Clin Gastroenterol Hepatol , vol.7 , pp. 874-81
    • Siegel, C.A.1    Marden, S.M.2    Persing, S.M.3
  • 32
    • 33846592386 scopus 로고    scopus 로고
    • Hepatosplenic T cell lymphoma associated with infliximab use in young patients treated for inflammatory bowel disease
    • DOI 10.1097/MPG.0b013e31802f6424, PII 0000517620070200000019
    • Mackey AC, Green L, Liang LC et al Hepatosplenic T cell lymphoma associated with inf iximab use in young patients treated for Infammatory bowel disease. J Pediatr Gastroenterol Nutr 2007;44:265-7. (Pubitemid 46175082)
    • (2007) Journal of Pediatric Gastroenterology and Nutrition , vol.44 , Issue.2 , pp. 265-267
    • Mackey, A.C.1    Green, L.2    Liang, L.-C.3    Dinndorf, P.4    Avigan, M.5
  • 33
    • 56549085510 scopus 로고    scopus 로고
    • Hepatosplenic T cell lymphoma in Infammatory bowel disease
    • Shale M, Kanfer E, Panaccione R et al Hepatosplenic T cell lymphoma in Infammatory bowel disease. Gut 2008; 57: 1639-41.
    • (2008) Gut , vol.57 , pp. 1639-41
    • Shale, M.1    Kanfer, E.2    Panaccione, R.3
  • 35
    • 0041334132 scopus 로고    scopus 로고
    • Therapeutic value of alpha-4 integrin blockade in inflammatory bowel disease: The role of natalizumab
    • DOI 10.1517/eobt.3.6.995.21264
    • Ghosh S. Terapeutic value of alpha-4 integrin blockade in Infammatory bowel disease: the role of natalizumab. Expert Opin Biol Ter 2003;3: 995-1000. (Pubitemid 37093154)
    • (2003) Expert Opinion on Biological Therapy , vol.3 , Issue.6 , pp. 995-1000
    • Ghosh, S.1
  • 37
    • 33644605483 scopus 로고    scopus 로고
    • Evaluation of patients treated with natalizumab for progressive multifocal leukoencephalopathy
    • Yousry TA, Major EO, Ryschkewitsch C et al Evaluation of patients treated with natalizumab for progressive multifocal leukoencephalopathy N Engl J Med 2006;354:924-33.
    • (2006) N Engl J Med , vol.354 , pp. 924-33
    • Yousry, T.A.1    Major, E.O.2    Ryschkewitsch, C.3
  • 38
    • 33845384834 scopus 로고    scopus 로고
    • Review article: Altering the natural history of Crohn's disease - Evidence for and against current therapies
    • DOI 10.1111/j.1365-2036.2006.03134.x
    • Vermeire S, van Assche G, Rutgeerts P. Review article: altering the natural history of Crohn's disease\evidence for and against current therapies. Aliment Pharmacol Ter 2007;25:3-12. (Pubitemid 44902859)
    • (2007) Alimentary Pharmacology and Therapeutics , vol.25 , Issue.1 , pp. 3-12
    • Vermeire, S.1    Van Assche, G.2    Rutgeerts, P.3
  • 39
    • 70450164329 scopus 로고    scopus 로고
    • Endpoints for clinical trials evaluating disease modif cation and structural damage in adults with Crohn's disease
    • D'Haens GR Fedorak R, Lemann M et al Endpoints for clinical trials evaluating disease modif cation and structural damage in adults with Crohn's disease. Infamm Bowel Dis 2009;15:1599-604.
    • (2009) Infamm Bowel Dis , vol.15 , pp. 1599-604
    • D'Haens, G.R.1    Fedorak, R.2    Lemann, M.3
  • 40
    • 33845660797 scopus 로고    scopus 로고
    • Individualized monitoring of drug bioavailability and immunogenicity in rheumatoid arthritis patients treated with the tumor necrosis factor α inhibitor infliximab
    • DOI 10.1002/art.22214
    • Bendtzen K, Geborek P Svenson M et al. Individualized monitoring of drug bioavailability and immunogenicity in rheumatoid arthritis patients treated with the tumor necrosis factor alpha inhibitor inf iximab. Arthritis Rheum 2006;54:3782-9. (Pubitemid 44955878)
    • (2006) Arthritis and Rheumatism , vol.54 , Issue.12 , pp. 3782-3789
    • Bendtzen, K.1    Geborek, P.2    Svenson, M.3    Larsson, L.4    Kapetanovic, M.C.5    Saxne, T.6
  • 41
    • 41849135759 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha binding capacity and anti-infliximab antibodies measured by fluid-phase radioimmunoassays as predictors of clinical efficacy of infliximab in Crohn's disease
    • DOI 10.1111/j.1572-0241.2007.01638.x
    • Ainsworth MA, Bendtzen K, Brynskov J. Tumor necrosis factor-alpha binding capacity and anti-inf iximab antibodies measured by f uid-phase radioimmunoassays as predictors of clinical ef cacy of inf iximab in Crohn's disease. Am J Gastroenterol 2008; 103: 944-8. (Pubitemid 351501078)
    • (2008) American Journal of Gastroenterology , vol.103 , Issue.4 , pp. 944-948
    • Ainsworth, M.A.1    Bendtzen, K.2    Brynskov, J.3
  • 42
    • 55449085485 scopus 로고    scopus 로고
    • Non-response to inf iximab may be due to innate neutralizing anti-tumour necrosis factor-alpha antibodies
    • Teber Te C, Das KM, Mehta V et al Non-response to inf iximab may be due to innate neutralizing anti-tumour necrosis factor-alpha antibodies. Clin Exp Immunol 2008;154:325-31.
    • (2008) Clin Exp Immunol , vol.154 , pp. 325-31
    • Teber Te, C.1    Das, K.M.2    Mehta, V.3
  • 45
    • 0033761188 scopus 로고    scopus 로고
    • Prolonged duration of response to inf iximab in early but not late pediatric Crohn's disease
    • Kugathasan S, Werlin SL, Martinez A et al Prolonged duration of response to inf iximab in early but not late pediatric Crohn's disease. Am J Gastroenterol 2000;95:3189-94.
    • (2000) Am J Gastroenterol , vol.95 , pp. 3189-94
    • Kugathasan, S.1    Werlin, S.L.2    Martinez, A.3
  • 49
    • 72549108185 scopus 로고    scopus 로고
    • Mucosal gene signatures to predict response to inf iximab in patients with ulcerative colitis
    • Arijs I, Li K, Toedter G et al Mucosal gene signatures to predict response to inf iximab in patients with ulcerative colitis. Gut 2009; 58: 1612-9.
    • (2009) Gut , vol.58 , pp. 1612-9
    • Arijs, I.1    Li, K.2    Toedter, G.3
  • 53
    • 0037379792 scopus 로고    scopus 로고
    • Intravenous hydrocortisone premedication reduces antibodies to infliximab in Crohn's disease: A randomized controlled trial
    • DOI 10.1053/gast.2003.50145
    • Farrell RJ, Alsahli M, Jeen YTet al Intravenous hydrocortisone premedi-cation reduces antibodies to inf iximab in Crohn's disease: a randomized controlled trial. Gastroenterology 2003; 124: 917-24. (Pubitemid 36389794)
    • (2003) Gastroenterology , vol.124 , Issue.4 , pp. 917-924
    • Farrell, R.J.1    Alsahli, M.2    Jeen, Y.-T.3    Falchuk, K.R.4    Peppercorn, M.A.5    Michetti, P.6
  • 54
    • 34548130215 scopus 로고    scopus 로고
    • Effectiveness of concomitant immunosuppressive therapy in suppressing the formation of antibodies to infliximab in Crohn's disease
    • DOI 10.1136/gut.2006.099978
    • Vermeire S, Noman M, Van Assche G et al effectiveness of concomitant immunosuppressive therapy in suppressing the formation of antibodies to infiximab in Crohn's disease. Gut 2007;56:1226-31. (Pubitemid 47300423)
    • (2007) Gut , vol.56 , Issue.9 , pp. 1226-1231
    • Vermeire, S.1    Noman, M.2    Van Assche, G.3    Baert, F.4    D'Haens, G.5    Rutgeerts, P.6
  • 56
    • 70350645060 scopus 로고    scopus 로고
    • Individual medicine in Infammatory bowel disease: Monitoring bioavailability pharmacokinetics and immunogenicity of anti-tumour necrosis factor-alpha antibodies
    • Bendtzen K, Ainsworth M, Steenholdt C et al Individual medicine in Infammatory bowel disease: monitoring bioavailability pharmacokinetics and immunogenicity of anti-tumour necrosis factor-alpha antibodies. Scand J Gastroenterol 2009;44:1-8.
    • (2009) Scand J Gastroenterol , vol.44 , pp. 1-8
    • Bendtzen, K.1    Ainsworth, M.2    Steenholdt, C.3
  • 57
    • 36448985258 scopus 로고    scopus 로고
    • Monitoring patients treated with anti-TNF-α biopharmaceuticals: Assessing serum infliximab and anti-infliximab antibodies
    • DOI 10.1093/rheumatology/kem261
    • Svenson M, Geborek P Saxne Tet al Monitoring patients treated with anti-TNF-alpha biopharmaceuticals: assessing serum inf iximab and anti-infiximab antibodies. Rheumatology (Oxford) 2007;46:1828-34. (Pubitemid 350168300)
    • (2007) Rheumatology , vol.46 , Issue.12 , pp. 1828-1834
    • Svenson, M.1    Geborek, P.2    Saxne, T.3    Bendtzen, K.4
  • 58
    • 0027361432 scopus 로고
    • Construction and initial characterization of a mouse-human chimeric anti-TNF antibody
    • Knight DM, Trinh H, Le J et al Construction and initial characterization of a mouse-human chimeric anti-TNF antibody Mol Immunol 1993; 30:1443-53.
    • (1993) Mol Immunol , vol.30 , pp. 1443-53
    • Knight, D.M.1    Trinh, H.2    Le, J.3
  • 59
    • 0036269445 scopus 로고    scopus 로고
    • The relationship of serum infliximab concentrations to clinical improvement in rheumatoid arthritis: Results from ATTRACT, a multicenter, randomized, double-blind, placebo-controlled trial
    • DOI 10.1002/art.10302
    • St Clair EW, Wagner CL, Fasanmade AA et al Te relationship of serum inf iximab concentrations to clinical improvement in rheumatoid arthritis: results from ATTRACT, a multicenter, randomized, double-blind, placebo-controlled trial. Arthritis Rheum 2002; 46: 1451-9. (Pubitemid 34620190)
    • (2002) Arthritis and Rheumatism , vol.46 , Issue.6 , pp. 1451-1459
    • St Clair, E.W.1    Wagner, C.L.2    Fasanmade, A.A.3    Wang, B.4    Schaible, T.5    Kavanaugh, A.6    Keystone, E.C.7
  • 60
    • 77950213411 scopus 로고    scopus 로고
    • Trough inf iximab concentrations predicTef cacy and sustained control of disease activity in rheumatoid arthritis
    • Mulleman D, Chu Miow Lin D, Ducourau E et al Trough inf iximab concentrations predicTef cacy and sustained control of disease activity in rheumatoid arthritis. Ter Drug Monit 2010;32:232-6.
    • (2010) Ter Drug Monit , vol.32 , pp. 232-6
    • Mulleman, D.1    Chu Miow Lin, D.2    Ducourau, E.3
  • 61
    • 34247179007 scopus 로고    scopus 로고
    • A relationship between pharmacokinetics (PK) and the efficacy of infliximab for patients with rheumatoid arthritis: Characterization of infliximab-resistant cases and PK-based modified therapy
    • DOI 10.1007/s10165-006-0544-9
    • Mori S. A relationship between pharmacokinetics (PK) and the ef cacy of inf iximab for patients with rheumatoid arthritis: characterization of inf iximab-resistant cases and PK-based modif ed therapy. Mod Rheumatol 2007;17:83-91. (Pubitemid 46614350)
    • (2007) Modern Rheumatology , vol.17 , Issue.2 , pp. 83-91
    • Mori, S.1
  • 62
    • 17644382690 scopus 로고    scopus 로고
    • Relationship between serum trough infliximab levels, pretreatment C reactive protein levels, and clinical response to infliximab treatment in patients with rheumatoid arthritis
    • DOI 10.1136/ard.2004.030452
    • Wolbink GJ, Voskuyl AE, Lems WF et al Relationship between serum trough inf iximab levels, pretreatment C reactive protein levels, and clinical response to inf iximab treatment in patients with rheumatoid arthritis. Ann Rheum Dis 2005;64:704-7. (Pubitemid 40559296)
    • (2005) Annals of the Rheumatic Diseases , vol.64 , Issue.5 , pp. 704-707
    • Wolbink, G.J.1    Voskuyl, A.E.2    Lems, W.F.3    De Groot, E.4    Nurmohamed, M.T.5    Tak, P.P.6    Dijkmans, B.A.C.7    Aarden, L.8
  • 63
    • 73449088039 scopus 로고    scopus 로고
    • Trough serum inf iximab: A predic-tive factor of clinical outcome for inf iximab treatment in acute ulcerative colitis
    • Seow CH, Newman A, Irwin SP et al. Trough serum inf iximab: a predic-tive factor of clinical outcome for inf iximab treatment in acute ulcerative colitis. Gut 2010;59:49-54.
    • (2010) Gut , vol.59 , pp. 49-54
    • Seow, C.H.1    Newman, A.2    Irwin, S.P.3
  • 64
    • 78650968267 scopus 로고    scopus 로고
    • Evaluation ofpotential correlations between serum adalimumab concentration and remission in patients with Crohn's disease in classic i and II
    • Li J, Paulson S, Chiu Y et al Evaluation ofpotential correlations between serum adalimumab concentration and remission in patients with Crohn's disease in classic I and II. Gastroenterology 2010; 138: 741.
    • (2010) Gastroenterology , vol.138 , pp. 741
    • Li, J.1    Paulson, S.2    Chiu, Y.3
  • 65
    • 70350130547 scopus 로고    scopus 로고
    • Inf uence of trough serum levels and immunogenicity on long-term outcome of adalimumab therapy in Crohn's disease
    • Karmiris K, Paintaud G, Noman M et al Inf uence of trough serum levels and immunogenicity on long-term outcome of adalimumab therapy in Crohn's disease. Gastroenterology 2009;137:1628-40.
    • (2009) Gastroenterology , vol.137 , pp. 1628-40
    • Karmiris, K.1    Paintaud, G.2    Noman, M.3
  • 66
    • 70449725246 scopus 로고    scopus 로고
    • Formation of antibodies against inf iximab and adalimumab strongly correlates with functional drug levels and clinical responses in rheumatoid arthritis
    • Radstake TR, Svenson M, Eijsbouts AM et al. Formation of antibodies against inf iximab and adalimumab strongly correlates with functional drug levels and clinical responses in rheumatoid arthritis. Ann Rheum Dis 2009;68:1739-45.
    • (2009) Ann Rheum Dis , vol.68 , pp. 1739-45
    • Radstake, T.R.1    Svenson, M.2    Eijsbouts, A.M.3
  • 68
    • 63849101007 scopus 로고    scopus 로고
    • Long-term outcome of treatment with inf iximab in 614 patients with Crohn's disease: Results from a single-centre cohort
    • Schnitzler F, Fidder H, Ferrante M et al. Long-term outcome of treatment with inf iximab in 614 patients with Crohn's disease: results from a single-centre cohort. Gut 2009;58:492-500.
    • (2009) Gut , vol.58 , pp. 492-500
    • Schnitzler, F.1    Fidder, H.2    Ferrante, M.3
  • 69
    • 0348109372 scopus 로고    scopus 로고
    • Adalimumab, a Fully Human Anti-Tumor Necrosis Factor-α Monoclonal Antibody, and Concomitant Standard Antirheumatic Therapy for the Treatment of Rheumatoid Arthritis: Results of STAR (Safety Trial of Adalimumab in Rheumatoid Arthritis)
    • Furst DE, Schif MH, Fleischmann RM et al Adalimumab, a fully human anti tumor necrosis factor-alpha monoclonal antibody, and concomitant standard antirheumatic therapy for the treatment of rheumatoid arthritis: results of STAR (Safety Trial of Adalimumab in Rheumatoid Arthritis). J Rheumatol 2003 30: 2563-71. (Pubitemid 37549331)
    • (2003) Journal of Rheumatology , vol.30 , Issue.12 , pp. 2563-2571
    • Furst, D.E.1    Schiff, M.H.2    Fleischmann, R.M.3    Strand, V.4    Birbara, C.A.5    Compagnone, D.6    Fischkoff, S.A.7    Chartash, E.K.8
  • 70
    • 2342658406 scopus 로고    scopus 로고
    • Radiographic, Clinical, and Functional Outcomes of Treatment with Adalimumab (a Human Anti-Tumor Necrosis Factor Monoclonal Antibody) in Patients with Active Rheumatoid Arthritis Receiving Concomitant Methotrexate Therapy: A Randomized, Placebo-Controlled, 52-Week Trial
    • DOI 10.1002/art.20217
    • Keystone EC, Kavanaugh AF, Sharp JTet al Radiographic, clinical, and functional outcomes of treatment with adalimumab (a human anti-tumor necrosis factor monoclonal antibody) in patients with active rheumatoid arthritis receiving concomitant methotrexate therapy: a randomized, placebo-controlled, 52-week trial. Arthritis Rheum 2004;50:1400-11. (Pubitemid 38608061)
    • (2004) Arthritis and Rheumatism , vol.50 , Issue.5 , pp. 1400-1411
    • Keystone, E.C.1    Kavanaugh, A.F.2    Sharp, J.T.3    Tannenbaum, H.4    Hua, Y.5    Teoh, L.S.6    Fischkoff, S.A.7    Chartash, E.K.8
  • 71
    • 0034735842 scopus 로고    scopus 로고
    • Inf iximab and meth-otrexate in the treatment of rheumatoid arthritis. Anti-Tumor Necrosis Factor Trial in Rheumatoid Arthritis with Concomitant Terapy Study Group
    • Lipsky PE, van der Heijde DM, St Clair EW et al Inf iximab and meth-otrexate in the treatment of rheumatoid arthritis. Anti-Tumor Necrosis Factor Trial in Rheumatoid Arthritis with Concomitant Terapy Study Group. N Engl J Med 2000;343:1594-602.
    • (2000) N Engl J Med , vol.343 , pp. 1594-602
    • Lipsky, P.E.1    Van Der Heijde, D.M.2    St Clair, E.W.3
  • 72
    • 0033524159 scopus 로고    scopus 로고
    • Inf iximab (chimeric anti-tumour necrosis factor alpha monoclonal antibody) versus placebo in rheumatoid arthritis patients receiving concomitant methotrexate: A randomised phase III trial
    • ATTRACT Study Group
    • Maini R St Clair EW, Breedveld F et al Inf iximab (chimeric anti-tumour necrosis factor alpha monoclonal antibody) versus placebo in rheumatoid arthritis patients receiving concomitant methotrexate: a randomised phase III trial. ATTRACT Study Group. Lancet 1999;354:1932-9.
    • (1999) Lancet , vol.354 , pp. 1932-9
    • Maini, R.1    St Clair, E.W.2    Breedveld, F.3
  • 77
    • 70350684087 scopus 로고    scopus 로고
    • 751f one year data from the sonic study: A randomized double-blind trial comparing inf iximab and inf iximab plus azathioprine to azathioprine in patients with Crohn's disease naive to immunomodulators and biologic therapy
    • Sandborn WJ, Rutgeerts PJ, Reinisch W et al 751f one year data from the sonic study: a randomized, double-blind trial comparing inf iximab and inf iximab plus azathioprine to azathioprine in patients with Crohn's disease naive to immunomodulators and biologic therapy Gastro enterology 2009;136:A-116.
    • (2009) Gastro Enterology , vol.136
    • Sandborn, W.J.1    Rutgeerts, P.J.2    Reinisch, W.3
  • 78
    • 47349125355 scopus 로고    scopus 로고
    • An open-label pilot study of the effectiveness of adalimumab in patients with rheumatoid arthritis and previous inf iximab treatment: Relationship to reasons for failure and anti-infiximab antibody status
    • van der Bijl AE, Breedveld FC, Antoni CE et al An open-label pilot study of the effectiveness of adalimumab in patients with rheumatoid arthritis and previous inf iximab treatment: relationship to reasons for failure and anti-infiximab antibody status. Clin Rheumatol 2008;27:1021-8.
    • (2008) Clin Rheumatol , vol.27 , pp. 1021-8
    • Van Der Bijl, A.E.1    Breedveld, F.C.2    Antoni, C.E.3
  • 80
    • 38149077059 scopus 로고    scopus 로고
    • Te use of adalimumab in the management of refractory Crohn's disease
    • Ho GT, Smith L, Aitken S et al Te use of adalimumab in the management of refractory Crohn's disease. Aliment Pharmacol Ter 2008;27:308-15.
    • (2008) Aliment Pharmacol ter , vol.27 , pp. 308-15
    • Ho, G.T.1    Smith, L.2    Aitken, S.3
  • 81
    • 49749148697 scopus 로고    scopus 로고
    • Successful induction of clinical response and remission with certolizumab pegol in Crohn's disease patients refractory or intolerant to inf iximab: A real-life multicenter experience of compassionate use
    • Danese S,Mocciaro F, GuidiLet al. Successful induction of clinical response and remission with certolizumab pegol in Crohn's disease patients refractory or intolerant to inf iximab: a real-life multicenter experience of compassionate use. Infamm Bowel Dis 2008;14:1168-70.
    • (2008) Infamm Bowel Dis , vol.14 , pp. 1168-70
    • Danese, S.1    Mocciaro, F.2    Guidi, L.3
  • 82
    • 64549161956 scopus 로고    scopus 로고
    • Treatment options in patients with rheu-matoid arthritis failing initial TNF inhibitor therapy: A critical review
    • Rubbert-Roth A, Finckh A. Treatment options in patients with rheu-matoid arthritis failing initial TNF inhibitor therapy: a critical review Arthritis Res Ter 2009;11 (Suppl1): S1.
    • (2009) Arthritis Res ter , vol.11 , Issue.SUPPL. 1
    • Rubbert-Roth, A.1    Finckh, A.2
  • 84
    • 77951974444 scopus 로고    scopus 로고
    • Clinical utility of measuring inf iximab and human anti-chimeric antibody concentrations in patients with infammatorybowel disease
    • Aff W, Lofus EV Jr, Faubion WA et al Clinical utility of measuring inf iximab and human anti-chimeric antibody concentrations in patients with infammatorybowel disease. Am J Gastroenterol 2010;105:1133-9.
    • (2010) Am J Gastroenterol , vol.105 , pp. 1133-9
    • Aff, W.1    Lofus Jr., E.V.2    Faubion, W.A.3
  • 85
    • 36549063053 scopus 로고    scopus 로고
    • Infliximab dose escalation vs. initiation of adalimumab for loss of response in Crohn's disease: A cost-effectiveness analysis
    • DOI 10.1111/j.1365-2036.2007.03548.x
    • Kaplan GG, Hur C, Korzenik J et al Inf iximab dose escalation vs. initiation of adalimumab for loss of response in Crohn's disease: a cost-effectiveness analysis. Aliment Pharmacol Ter 2007;26:1509-20. (Pubitemid 350178810)
    • (2007) Alimentary Pharmacology and Therapeutics , vol.26 , Issue.11-12 , pp. 1509-1520
    • Kaplan, G.G.1    Hur, C.2    Korzenik, J.3    Sands, B.E.4
  • 86
    • 34648873396 scopus 로고    scopus 로고
    • Re-induction and maintenance therapy with subcutaneous certolizumab pegol in patients with Crohn's disease following treatment failure: PRECiSE 4 results
    • Sandborn WJ, Hanauer SB, Rutgeerts PJ et al Re-induction and maintenance therapy with subcutaneous certolizumab pegol in patients with Crohn's disease following treatment failure: PRECiSE 4 results. Gastroenterology 2007;132:A505.
    • (2007) Gastroenterology , vol.132
    • Sandborn, W.J.1    Hanauer, S.B.2    Rutgeerts, P.J.3
  • 87
    • 63849102069 scopus 로고    scopus 로고
    • Review article: Anti TNF-alpha induced psoriasis in patients with infammatory bowel disease
    • Fiorino G, Allez M, Malesci A et al Review article: anti TNF-alpha induced psoriasis in patients with infammatory bowel disease. Aliment Pharmacol Ter 2009;29:921-7.
    • (2009) Aliment Pharmacol ter , vol.29 , pp. 921-7
    • Fiorino, G.1    Allez, M.2    Malesci, A.3
  • 88
    • 70450222544 scopus 로고    scopus 로고
    • Emergence of Crohn's disease during treatment with the anti-tumor necrosis factor agenTetanercept for ankylosing spondyli-tis: Possible mechanisms of action
    • Haraoui B, Krelenbaum M. Emergence of Crohn's disease during treatment with the anti-tumor necrosis factor agenTetanercept for ankylosing spondyli-tis: possible mechanisms of action. Semin Arthritis Rheum 2009; 39: 176-81.
    • (2009) Semin Arthritis Rheum , vol.39 , pp. 176-81
    • Haraoui, B.1    Krelenbaum, M.2
  • 91
    • 34248545097 scopus 로고    scopus 로고
    • B cell depletion may be more effective than switching to an alternative anti-tumor necrosis factor agent in rheumatoid arthritis patients with inadequate response to anti-tumor necrosis factor agents
    • DOI 10.1002/art.22520
    • Finckh A, Ciurea A, Brulhart L et al B cell depletion may be more effective than switching to an alternative anti-tumor necrosis factor agent in rheumatoid arthritis patients with inadequate response to anti-tumor necrosis factor agents. Arthritis Rheum 2007;56:1417-23. (Pubitemid 46764068)
    • (2007) Arthritis and Rheumatism , vol.56 , Issue.5 , pp. 1417-1423
    • Finckh, A.1    Ciurea, A.2    Brulhart, L.3    Kyburz, D.4    Moller, B.5    Dehler, S.6    Revaz, S.7    Dudler, J.8    Gabay, C.9
  • 92
    • 75749106664 scopus 로고    scopus 로고
    • Which subgroup of rheumatoid arthritis patients benef ts from switching to rituximab versus alternative anti-TNF agents afer previous failure to anti-TNF agent?
    • Finckh A, Ciurea A, Brulhart L et al. Which subgroup of rheumatoid arthritis patients benef ts from switching to rituximab versus alternative anti-TNF agents afer previous failure to anti-TNF agent? Ann Rheum Dis 2010;69:387-93.
    • (2010) Ann Rheum Dis , vol.69 , pp. 387-93
    • Finckh, A.1    Ciurea, A.2    Brulhart, L.3
  • 94
    • 46749122184 scopus 로고    scopus 로고
    • Effcacy and safety of certolizu-mab pegol in patients with active Crohn's disease who previously lost response or were intolerant to inf iximab: Open-label induction preliminary results of the WELCOME study
    • Vermeire S, Abreu MT, D'Haens G et al. Effcacy and safety of certolizu-mab pegol in patients with active Crohn's disease who previously lost response or were intolerant to inf iximab: open-label induction preliminary results of the WELCOME study. Gastroenterology 2008;134: A-67-8.
    • (2008) Gastroenterology , vol.134
    • Vermeire, S.1    Abreu, M.T.2    D'Haens, G.3
  • 95
    • 46749092439 scopus 로고    scopus 로고
    • 920 Adalimumab maintains long-term remission in moderately to severely active Crohn's disease af er inf iximab failure: 1-year follow-up of gain trial
    • Panaccione R, Sandborn WJ, D'Haens G et al 920 Adalimumab maintains long-term remission in moderately to severely active Crohn's disease af er inf iximab failure: 1-year follow-up of gain trial. Gastroenterology 2008;134:A-133-4.
    • (2008) Gastroenterology , vol.134
    • Panaccione, R.1    Sandborn, W.J.2    D'Haens, G.3
  • 96
    • 58149302486 scopus 로고    scopus 로고
    • Adalimumab for Crohn's disease with intolerance or lost response to inf iximab: A 3-year single-centre experience
    • Oussalah A, Babouri A, Chevaux JB et al Adalimumab for Crohn's disease with intolerance or lost response to inf iximab: a 3-year single-centre experience. Aliment Pharmacol Ter 2009;29:416-23.
    • (2009) Aliment Pharmacol ter , vol.29 , pp. 416-23
    • Oussalah, A.1    Babouri, A.2    Chevaux, J.B.3
  • 97
    • 79953784270 scopus 로고    scopus 로고
    • T1061 Improvement in short inf am-matory bowel disease questionnaire scores in adalimumab-treated Crohn's disease patients who failed infiximab (CHOICE trial)
    • Lichtiger S, Present DH, Wu E et al T1061 Improvement in short inf am-matory bowel disease questionnaire scores in adalimumab-treated Crohn's disease patients who failed infiximab (CHOICE trial). Gastroenterology 2008;134:A-474-5.
    • (2008) Gastroenterology , vol.134
    • Lichtiger, S.1    Present, D.H.2    Wu, E.3
  • 98
    • 71449114736 scopus 로고    scopus 로고
    • Te Effcacy and safety of a third anti-TNF monoclonal antibody in Crohn's disease af er failure of two other anti-TNF antibodies
    • Allez M, Vermeire S, Mozziconacci N et al Te Effcacy and safety of a third anti-TNF monoclonal antibody in Crohn's disease af er failure of two other anti-TNF antibodies. Aliment Pharmacol Ter 2010;31:92-101.
    • (2010) Aliment Pharmacol ter , vol.31 , pp. 92-101
    • Allez, M.1    Vermeire, S.2    Mozziconacci, N.3
  • 99
    • 79953803717 scopus 로고    scopus 로고
    • Natalizumab induces sustained response and remission in the absence of concomitant immunosuppres-sants in patients with crohn's disease who failed prior anti-TNF α therapy
    • Lashner B, Colombel JF, Enns R et al Natalizumab induces sustained response and remission in the absence of concomitant immunosuppres-sants in patients with crohn's disease who failed prior anti-TNF α therapy Am J Gastroenterol 2007;102 (Suppl2): S493.
    • (2007) Am J Gastroenterol , vol.102 , Issue.SUPPL. 2
    • Lashner, B.1    Colombel, J.F.2    Enns, R.3
  • 100
    • 79955859430 scopus 로고    scopus 로고
    • Adalimumab for induction of clinical remission in moderately to severely active ulcerative colitis: Results of a randomised controlled trial
    • Reinisch W Sandborn WJ, Hommes DW et al Adalimumab for induction of clinical remission in moderately to severely active ulcerative colitis: results of a randomised controlled trial. Gut 2011.
    • (2011) Gut
    • Reinisch, W.1    Sandborn, W.J.2    Hommes, D.W.3
  • 101
    • 78649235240 scopus 로고    scopus 로고
    • Long-term Effects and colectomy rates in ulcerative colitis patients treated with inf iximab: A Danish single center experience
    • Teisner AS, Ainsworth MA, Brynskov J. Long-term Effects and colectomy rates in ulcerative colitis patients treated with inf iximab: a Danish single center experience. Scand J Gastroenterol 2010;45:1457-63.
    • (2010) Scand J Gastroenterol , vol.45 , pp. 1457-63
    • Teisner, A.S.1    Ainsworth, M.A.2    Brynskov, J.3


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