-
1
-
-
83655181087
-
Bacteria and host interactions in the gut epithelial barrier
-
Ashida H, Ogawa M, Kim M, Mimuro H, Sasakawa C. 2012. Bacteria and host interactions in the gut epithelial barrier. Nat. Chem. Biol. 8:36-45.
-
(2012)
Nat. Chem. Biol.
, vol.8
, pp. 36-45
-
-
Ashida, H.1
Ogawa, M.2
Kim, M.3
Mimuro, H.4
Sasakawa, C.5
-
2
-
-
83055184684
-
Epithelial barrier biology: good fences make good neighbours
-
Moens E, Veldhoen M. 2012. Epithelial barrier biology: good fences make good neighbours. Immunology 135:1-8.
-
(2012)
Immunology
, vol.135
, pp. 1-8
-
-
Moens, E.1
Veldhoen, M.2
-
3
-
-
83655191565
-
Epithelial barrier: an interface for the crosscommunication between gut flora and immune system
-
Goto Y, Kiyono H. 2012. Epithelial barrier: an interface for the crosscommunication between gut flora and immune system. Immunol. Rev. 245:147-163.
-
(2012)
Immunol. Rev.
, vol.245
, pp. 147-163
-
-
Goto, Y.1
Kiyono, H.2
-
4
-
-
0033558504
-
Lineage commitment and maturation of epithelial cells in the gut
-
Karam SM. 1999. Lineage commitment and maturation of epithelial cells in the gut. Front. Biosci. 4:D286-D298.
-
(1999)
Front. Biosci.
, vol.4
-
-
Karam, S.M.1
-
7
-
-
4544300682
-
RELMbeta/FIZZ2 is a goblet cell-specific immune-effector molecule in the gastrointestinal tract
-
Artis D, Wang ML, Keilbaugh SA, He W, Brenes M, Swain GP, Knight PA, Donaldson DD, Lazar MA, Miller HR, Schad GA, Scott P, Wu GD. 2004. RELMbeta/FIZZ2 is a goblet cell-specific immune-effector molecule in the gastrointestinal tract. Proc. Natl. Acad. Sci. U. S. A. 101:13596-13600.
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 13596-13600
-
-
Artis, D.1
Wang, M.L.2
Keilbaugh, S.A.3
He, W.4
Brenes, M.5
Swain, G.P.6
Knight, P.A.7
Donaldson, D.D.8
Lazar, M.A.9
Miller, H.R.10
Schad, G.A.11
Scott, P.12
Wu, G.D.13
-
8
-
-
67651159312
-
Stem cells, self-renewal, and differentiation in the intestinal epithelium
-
van der Flier LG, Clevers H. 2009. Stem cells, self-renewal, and differentiation in the intestinal epithelium. Annu. Rev. Physiol. 71:241-260.
-
(2009)
Annu. Rev. Physiol.
, vol.71
, pp. 241-260
-
-
van der Flier, L.G.1
Clevers, H.2
-
9
-
-
20344379481
-
Accelerated intestinal epithelial cell turnover: a new mechanism of parasite expulsion
-
Cliffe LJ, Humphreys NE, Lane TE, Potten CS, Booth C, Grencis RK. 2005. Accelerated intestinal epithelial cell turnover: a new mechanism of parasite expulsion. Science 308:1463-1465.
-
(2005)
Science
, vol.308
, pp. 1463-1465
-
-
Cliffe, L.J.1
Humphreys, N.E.2
Lane, T.E.3
Potten, C.S.4
Booth, C.5
Grencis, R.K.6
-
10
-
-
0031050876
-
Altered expression of mucins throughout the colon in ulcerative colitis
-
Smithson JE, Campbell A, Andrews JM, Milton JD, Pigott R, Jewell DP. 1997. Altered expression of mucins throughout the colon in ulcerative colitis. Gut 40:234-240.
-
(1997)
Gut
, vol.40
, pp. 234-240
-
-
Smithson, J.E.1
Campbell, A.2
Andrews, J.M.3
Milton, J.D.4
Pigott, R.5
Jewell, D.P.6
-
11
-
-
0027254441
-
Glycosylation and sulphation of colonic mucus glycoproteins in patients with ulcerative colitis and in healthy subjects
-
Morita H, Kettlewell MG, Jewell DP, Kent PW. 1993. Glycosylation and sulphation of colonic mucus glycoproteins in patients with ulcerative colitis and in healthy subjects. Gut 34:926-932.
-
(1993)
Gut
, vol.34
, pp. 926-932
-
-
Morita, H.1
Kettlewell, M.G.2
Jewell, D.P.3
Kent, P.W.4
-
12
-
-
77957906400
-
Bacteria penetrate the inner mucus layer before inflammation in the dextran sulfate colitis model
-
doi:10.1371/journal.pone.0012238
-
Johansson ME, Gustafsson JK, Sjoberg KE, Petersson J, Holm L, Sjovall H, Hansson GC. 2010. Bacteria penetrate the inner mucus layer before inflammation in the dextran sulfate colitis model. PLoS One 5:e12238. doi:10.1371/journal.pone.0012238.
-
(2010)
PLoS One
, vol.5
-
-
Johansson, M.E.1
Gustafsson, J.K.2
Sjoberg, K.E.3
Petersson, J.4
Holm, L.5
Sjovall, H.6
Hansson, G.C.7
-
13
-
-
39149134612
-
Modulation of intestinal goblet cell function during infection by an attaching and effacing bacterial pathogen
-
Bergstrom KS, Guttman JA, Rumi M, Ma C, Bouzari S, Khan MA, Gibson DL, Vogl AW, Vallance BA. 2008. Modulation of intestinal goblet cell function during infection by an attaching and effacing bacterial pathogen. Infect. Immun. 76:796-811.
-
(2008)
Infect. Immun.
, vol.76
, pp. 796-811
-
-
Bergstrom, K.S.1
Guttman, J.A.2
Rumi, M.3
Ma, C.4
Bouzari, S.5
Khan, M.A.6
Gibson, D.L.7
Vogl, A.W.8
Vallance, B.A.9
-
14
-
-
0035029103
-
Molecular pathogenesis of Citrobacter rodentium and transmissible murine colonic hyperplasia
-
Luperchio SA, Schauer DB. 2001. Molecular pathogenesis of Citrobacter rodentium and transmissible murine colonic hyperplasia. Microbes Infect. 3:333-340.
-
(2001)
Microbes Infect.
, vol.3
, pp. 333-340
-
-
Luperchio, S.A.1
Schauer, D.B.2
-
15
-
-
0034994474
-
Microbial modulation of innate defense: goblet cells and the intestinal mucus layer
-
Deplancke B, Gaskins HR. 2001. Microbial modulation of innate defense: goblet cells and the intestinal mucus layer. Am. J. Clin. Nutr. 73:1131S-1141S.
-
(2001)
Am. J. Clin. Nutr.
, vol.73
-
-
Deplancke, B.1
Gaskins, H.R.2
-
16
-
-
44149126798
-
Secreted enteric antimicrobial activity localises to the mucus surface layer
-
Meyer-Hoffert U, Hornef MW, Henriques-Normark B, Axelsson LG, Midtvedt T, Putsep K, Andersson M. 2008. Secreted enteric antimicrobial activity localises to the mucus surface layer. Gut 57:764-771.
-
(2008)
Gut
, vol.57
, pp. 764-771
-
-
Meyer-Hoffert, U.1
Hornef, M.W.2
Henriques-Normark, B.3
Axelsson, L.G.4
Midtvedt, T.5
Putsep, K.6
Andersson, M.7
-
17
-
-
77953610970
-
Muc2 protects against lethal infectious colitis by disassociating pathogenic and commensal bacteria from the colonic mucosa
-
doi:10.1371/journal.ppat.1000902
-
Bergstrom KS, Kissoon-Singh V, Gibson DL, Ma C, Montero M, Sham HP, Ryz N, Huang T, Velcich A, Finlay BB, Chadee K, Vallance BA. 2010. Muc2 protects against lethal infectious colitis by disassociating pathogenic and commensal bacteria from the colonic mucosa. PLoS Pathog. 6:e1000902. doi:10.1371/journal.ppat.1000902.
-
(2010)
PLoS Pathog.
, vol.6
-
-
Bergstrom, K.S.1
Kissoon-Singh, V.2
Gibson, D.L.3
Ma, C.4
Montero, M.5
Sham, H.P.6
Ryz, N.7
Huang, T.8
Velcich, A.9
Finlay, B.B.10
Chadee, K.11
Vallance, B.A.12
-
18
-
-
33745121509
-
Entamoeba histolytica cysteine proteases cleave the MUC2 mucin in its C-terminal domain and dissolve the protective colonic mucus gel
-
Lidell ME, Moncada DM, Chadee K, Hansson GC. 2006. Entamoeba histolytica cysteine proteases cleave the MUC2 mucin in its C-terminal domain and dissolve the protective colonic mucus gel. Proc. Natl. Acad. Sci. U. S. A. 103:9298-9303.
-
(2006)
Proc. Natl. Acad. Sci. U. S. A.
, vol.103
, pp. 9298-9303
-
-
Lidell, M.E.1
Moncada, D.M.2
Chadee, K.3
Hansson, G.C.4
-
19
-
-
33644849683
-
Antisense inhibition of Entamoeba histolytica cysteine proteases inhibits colonic mucus degradation
-
Moncada D, Keller K, Ankri S, Mirelman D, Chadee K. 2006. Antisense inhibition of Entamoeba histolytica cysteine proteases inhibits colonic mucus degradation. Gastroenterology 130:721-730.
-
(2006)
Gastroenterology
, vol.130
, pp. 721-730
-
-
Moncada, D.1
Keller, K.2
Ankri, S.3
Mirelman, D.4
Chadee, K.5
-
20
-
-
67649231565
-
Colitis-associated variant of TLR2 causes impaired mucosal repair because of TFF3 deficiency
-
Podolsky DK, Gerken G, Eyking A, Cario E. 2009. Colitis-associated variant of TLR2 causes impaired mucosal repair because of TFF3 deficiency. Gastroenterology 137:209-220.
-
(2009)
Gastroenterology
, vol.137
, pp. 209-220
-
-
Podolsky, D.K.1
Gerken, G.2
Eyking, A.3
Cario, E.4
-
21
-
-
0242490269
-
Bacterial colonization leads to the colonic secretion of RELMbeta/FIZZ2, a novel goblet cell-specific protein
-
He W, Wang ML, Jiang HQ, Steppan CM, Shin ME, Thurnheer MC, Cebra JJ, Lazar MA, Wu GD. 2003. Bacterial colonization leads to the colonic secretion of RELMbeta/FIZZ2, a novel goblet cell-specific protein. Gastroenterology 125:1388-1397.
-
(2003)
Gastroenterology
, vol.125
, pp. 1388-1397
-
-
He, W.1
Wang, M.L.2
Jiang, H.Q.3
Steppan, C.M.4
Shin, M.E.5
Thurnheer, M.C.6
Cebra, J.J.7
Lazar, M.A.8
Wu, G.D.9
-
22
-
-
33745396463
-
Resistin-like molecule beta regulates innate colonic function: barrier integrity and inflammation susceptibility
-
Hogan SP, Seidu L, Blanchard C, Groschwitz K, Mishra A, Karow ML, Ahrens R, Artis D, Murphy AJ, Valenzuela DM, Yancopoulos GD, Rothenberg ME. 2006. Resistin-like molecule beta regulates innate colonic function: barrier integrity and inflammation susceptibility. J. Allergy Clin. Immunol. 118:257-268.
-
(2006)
J. Allergy Clin. Immunol.
, vol.118
, pp. 257-268
-
-
Hogan, S.P.1
Seidu, L.2
Blanchard, C.3
Groschwitz, K.4
Mishra, A.5
Karow, M.L.6
Ahrens, R.7
Artis, D.8
Murphy, A.J.9
Valenzuela, D.M.10
Yancopoulos, G.D.11
Rothenberg, M.E.12
-
23
-
-
33745594044
-
The gut flora as a forgotten organ
-
O'Hara AM, Shanahan F. 2006. The gut flora as a forgotten organ. EMBO Rep. 7:688-693.
-
(2006)
EMBO Rep.
, vol.7
, pp. 688-693
-
-
O'Hara, A.M.1
Shanahan, F.2
-
24
-
-
0036128828
-
Mice lacking T and B lymphocytes develop transient colitis and crypt hyperplasia yet suffer impaired bacterial clearance during Citrobacter rodentium infection
-
Vallance BA, Deng W, Knodler LA, Finlay BB. 2002. Mice lacking T and B lymphocytes develop transient colitis and crypt hyperplasia yet suffer impaired bacterial clearance during Citrobacter rodentium infection. Infect. Immun. 70:2070-2081.
-
(2002)
Infect. Immun.
, vol.70
, pp. 2070-2081
-
-
Vallance, B.A.1
Deng, W.2
Knodler, L.A.3
Finlay, B.B.4
-
25
-
-
0033984235
-
The Ki-67 protein: from the known and the unknown
-
Scholzen T, Gerdes J. 2000. The Ki-67 protein: from the known and the unknown. J. Cell. Physiol. 182:311-322.
-
(2000)
J. Cell. Physiol.
, vol.182
, pp. 311-322
-
-
Scholzen, T.1
Gerdes, J.2
-
26
-
-
33646560950
-
Transforming growth factor-beta induces development of the T(H)17 lineage
-
Mangan PR, Harrington LE, O'Quinn DB, Helms WS, Bullard DC, Elson CO, Hatton RD, Wahl SM, Schoeb TR, Weaver CT. 2006. Transforming growth factor-beta induces development of the T(H)17 lineage. Nature 441:231-234.
-
(2006)
Nature
, vol.441
, pp. 231-234
-
-
Mangan, P.R.1
Harrington, L.E.2
O'Quinn, D.B.3
Helms, W.S.4
Bullard, D.C.5
Elson, C.O.6
Hatton, R.D.7
Wahl, S.M.8
Schoeb, T.R.9
Weaver, C.T.10
-
27
-
-
58149231532
-
Differential roles of interleukin-17A and -17F in host defense against mucoepithelial bacterial infection and allergic responses
-
Ishigame H, Kakuta S, Nagai T, Kadoki M, Nambu A, Komiyama Y, Fujikado N, Tanahashi Y, Akitsu A, Kotaki H, Sudo K, Nakae S, Sasakawa C, Iwakura Y. 2009. Differential roles of interleukin-17A and -17F in host defense against mucoepithelial bacterial infection and allergic responses. Immunity 30:108-119.
-
(2009)
Immunity
, vol.30
, pp. 108-119
-
-
Ishigame, H.1
Kakuta, S.2
Nagai, T.3
Kadoki, M.4
Nambu, A.5
Komiyama, Y.6
Fujikado, N.7
Tanahashi, Y.8
Akitsu, A.9
Kotaki, H.10
Sudo, K.11
Nakae, S.12
Sasakawa, C.13
Iwakura, Y.14
-
28
-
-
26444433211
-
Interleukin-17 is a potent immuno-modulator and regulator of normal human intestinal epithelial cell growth
-
Schwartz S, Beaulieu JF, Ruemmele FM. 2005. Interleukin-17 is a potent immuno-modulator and regulator of normal human intestinal epithelial cell growth. Biochem. Biophys. Res. Commun. 337:505-509.
-
(2005)
Biochem. Biophys. Res. Commun.
, vol.337
, pp. 505-509
-
-
Schwartz, S.1
Beaulieu, J.F.2
Ruemmele, F.M.3
-
29
-
-
8444247084
-
Modulation of notch processing by gamma-secretase inhibitors causes intestinal goblet cell metaplasia and induction of genes known to specify gut secretory lineage differentiation
-
Milano J, McKay J, Dagenais C, Foster-Brown L, Pognan F, Gadient R, Jacobs RT, Zacco A, Greenberg B, Ciaccio PJ. 2004. Modulation of notch processing by gamma-secretase inhibitors causes intestinal goblet cell metaplasia and induction of genes known to specify gut secretory lineage differentiation. Toxicol. Sci. 82:341-358.
-
(2004)
Toxicol. Sci.
, vol.82
, pp. 341-358
-
-
Milano, J.1
McKay, J.2
Dagenais, C.3
Foster-Brown, L.4
Pognan, F.5
Gadient, R.6
Jacobs, R.T.7
Zacco, A.8
Greenberg, B.9
Ciaccio, P.J.10
-
30
-
-
0035824487
-
Requirement of Math1 for secretory cell lineage commitment in the mouse intestine
-
Yang Q, Bermingham NA, Finegold MJ, Zoghbi HY. 2001. Requirement of Math1 for secretory cell lineage commitment in the mouse intestine. Science 294:2155-2158.
-
(2001)
Science
, vol.294
, pp. 2155-2158
-
-
Yang, Q.1
Bermingham, N.A.2
Finegold, M.J.3
Zoghbi, H.Y.4
-
31
-
-
20544460148
-
Notch/gamma-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells
-
van Es JH, van Gijn ME, Riccio O, van den Born M, Vooijs M, Begthel H, Cozijnsen M, Robine S, Winton DJ, Radtke F, Clevers H. 2005. Notch/gamma-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells. Nature 435:959-963.
-
(2005)
Nature
, vol.435
, pp. 959-963
-
-
van Es, J.H.1
van Gijn, M.E.2
Riccio, O.3
van den Born, M.4
Vooijs, M.5
Begthel, H.6
Cozijnsen, M.7
Robine, S.8
Winton, D.J.9
Radtke, F.10
Clevers, H.11
-
32
-
-
0041322730
-
Central role for B lymphocytes and CD4+ T cells in immunity to infection by the attaching and effacing pathogen Citrobacter rodentium
-
Simmons CP, Clare S, Ghaem-Maghami M, Uren TK, Rankin J, Huett A, Goldin R, Lewis DJ, MacDonald TT, Strugnell RA, Frankel G, Dougan G. 2003. Central role for B lymphocytes and CD4+ T cells in immunity to infection by the attaching and effacing pathogen Citrobacter rodentium. Infect. Immun. 71:5077-5086.
-
(2003)
Infect. Immun.
, vol.71
, pp. 5077-5086
-
-
Simmons, C.P.1
Clare, S.2
Ghaem-Maghami, M.3
Uren, T.K.4
Rankin, J.5
Huett, A.6
Goldin, R.7
Lewis, D.J.8
MacDonald, T.T.9
Strugnell, R.A.10
Frankel, G.11
Dougan, G.12
-
33
-
-
0037083505
-
Impaired resistance and enhanced pathology during infection with a noninvasive, attaching-effacing enteric bacterial pathogen, Citrobacter rodentium, in mice lacking IL-12 or IFN-gamma
-
Simmons CP, Goncalves NS, Ghaem-Maghami M, Bajaj-Elliott M, Clare S, Neves B, Frankel G, Dougan G, MacDonald TT. 2002. Impaired resistance and enhanced pathology during infection with a noninvasive, attaching-effacing enteric bacterial pathogen, Citrobacter rodentium, in mice lacking IL-12 or IFN-gamma. J. Immunol. 168:1804-1812.
-
(2002)
J. Immunol.
, vol.168
, pp. 1804-1812
-
-
Simmons, C.P.1
Goncalves, N.S.2
Ghaem-Maghami, M.3
Bajaj-Elliott, M.4
Clare, S.5
Neves, B.6
Frankel, G.7
Dougan, G.8
MacDonald, T.T.9
-
34
-
-
77952684481
-
Gamma interferon produced by antigen-specific CD4+ T cells regulates the mucosal immune responses to Citrobacter rodentium infection
-
Shiomi H, Masuda A, Nishiumi S, Nishida M, Takagawa T, Shiomi Y, Kutsumi H, Blumberg RS, Azuma T, Yoshida M. 2010. Gamma interferon produced by antigen-specific CD4+ T cells regulates the mucosal immune responses to Citrobacter rodentium infection. Infect. Immun. 78:2653-2666.
-
(2010)
Infect. Immun.
, vol.78
, pp. 2653-2666
-
-
Shiomi, H.1
Masuda, A.2
Nishiumi, S.3
Nishida, M.4
Takagawa, T.5
Shiomi, Y.6
Kutsumi, H.7
Blumberg, R.S.8
Azuma, T.9
Yoshida, M.10
-
35
-
-
79960871920
-
Stromal IFN-gammaR-signaling modulates goblet cell function during Salmonella Typhimurium infection
-
doi:10.1371/journal.pone.0022459
-
Songhet P, Barthel M, Stecher B, Muller AJ, Kremer M, Hansson GC, Hardt WD. 2011. Stromal IFN-gammaR-signaling modulates goblet cell function during Salmonella Typhimurium infection. PLoS One 6:e22459. doi:10.1371/journal.pone.0022459.
-
(2011)
PLoS One
, vol.6
-
-
Songhet, P.1
Barthel, M.2
Stecher, B.3
Muller, A.J.4
Kremer, M.5
Hansson, G.C.6
Hardt, W.D.7
-
36
-
-
54449083567
-
The inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteria
-
Johansson ME, Phillipson M, Petersson J, Velcich A, Holm L, Hansson GC. 2008. The inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteria. Proc. Natl. Acad. Sci. U. S. A. 105:15064-15069.
-
(2008)
Proc. Natl. Acad. Sci. U. S. A.
, vol.105
, pp. 15064-15069
-
-
Johansson, M.E.1
Phillipson, M.2
Petersson, J.3
Velcich, A.4
Holm, L.5
Hansson, G.C.6
-
37
-
-
34548028239
-
Campylobacter jejuni: molecular biology and pathogenesis
-
Young KT, Davis LM, Dirita VJ. 2007. Campylobacter jejuni: molecular biology and pathogenesis. Nat. Rev. Microbiol. 5:665-679.
-
(2007)
Nat. Rev. Microbiol.
, vol.5
, pp. 665-679
-
-
Young, K.T.1
Davis, L.M.2
Dirita, V.J.3
-
38
-
-
77955714153
-
Early-stage blocking of Notch signaling inhibits the depletion of goblet cells in dextran sodium sulfate-induced colitis in mice
-
Shinoda M, Shin-Ya M, Naito Y, Kishida T, Ito R, Suzuki N, Yasuda H, Sakagami J, Imanishi J, Kataoka K, Mazda O, Yoshikawa T. 2010. Early-stage blocking of Notch signaling inhibits the depletion of goblet cells in dextran sodium sulfate-induced colitis in mice. J. Gastroenterol. 45:608-617.
-
(2010)
J. Gastroenterol.
, vol.45
, pp. 608-617
-
-
Shinoda, M.1
Shin-Ya, M.2
Naito, Y.3
Kishida, T.4
Ito, R.5
Suzuki, N.6
Yasuda, H.7
Sakagami, J.8
Imanishi, J.9
Kataoka, K.10
Mazda, O.11
Yoshikawa, T.12
-
39
-
-
34648814084
-
Crosstalk between Wnt and Notch signaling in intestinal epithelial cell fate decision
-
Nakamura T, Tsuchiya K, Watanabe M. 2007. Crosstalk between Wnt and Notch signaling in intestinal epithelial cell fate decision. J. Gastroenterol. 42:705-710.
-
(2007)
J. Gastroenterol.
, vol.42
, pp. 705-710
-
-
Nakamura, T.1
Tsuchiya, K.2
Watanabe, M.3
-
40
-
-
78650834843
-
Altered intestinal epithelial homeostasis in mice with intestine-specific deletion of the Kruppel-like factor 4 gene
-
Ghaleb AM, McConnell BB, Kaestner KH, Yang VW. 2011. Altered intestinal epithelial homeostasis in mice with intestine-specific deletion of the Kruppel-like factor 4 gene. Dev. Biol. 349:310-320.
-
(2011)
Dev. Biol.
, vol.349
, pp. 310-320
-
-
Ghaleb, A.M.1
McConnell, B.B.2
Kaestner, K.H.3
Yang, V.W.4
|