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Volumn 127, Issue 6, 2013, Pages 819-836

The notch signaling pathway: Its role in focal CNS demyelination and apotransferrin-induced remyelination

Author keywords

apotransferrin; demyelination; notch signalling; remyelination

Indexed keywords

APOTRANSFERRIN; CONTACTIN; GAMMA SECRETASE INHIBITOR; JAGGED1; LYSOPHOSPHATIDYLCHOLINE; MYELIN ASSOCIATED GLYCOPROTEIN; NESTIN; NOTCH RECEPTOR; TRANSCRIPTION FACTOR HES 5;

EID: 84890120483     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/jnc.12440     Document Type: Article
Times cited : (35)

References (53)
  • 2
    • 0033617522 scopus 로고    scopus 로고
    • Notch signaling: Cell fate control and signal integration in development
    • Artavanis-Tsakonas S., Rand M. D., and, Lake R. J., (1999) Notch signaling: cell fate control and signal integration in development. Science 284, 770-776.
    • (1999) Science , vol.284 , pp. 770-776
    • Artavanis-Tsakonas, S.1    Rand, M.D.2    Lake, R.J.3
  • 4
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford M. M., (1976) A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72, 248-254.
    • (1976) Anal. Biochem. , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 5
    • 0027466971 scopus 로고
    • Microglia present myelin antigens to T cells after phagocytosis of oligodendrocytes
    • Cash E., Zhang Y., and, Rott O., (1993) Microglia present myelin antigens to T cells after phagocytosis of oligodendrocytes. Cell. Immunol. 147, 129-138.
    • (1993) Cell. Immunol. , vol.147 , pp. 129-138
    • Cash, E.1    Zhang, Y.2    Rott, O.3
  • 6
    • 0037085715 scopus 로고    scopus 로고
    • Efficient recolonisation of progenitor-depleted areas of the CNS by adult oligodendrocyte progenitor cells
    • Chari D. M., and, Blakemore W. F., (2002) Efficient recolonisation of progenitor-depleted areas of the CNS by adult oligodendrocyte progenitor cells. Glia 37, 307-313.
    • (2002) Glia , vol.37 , pp. 307-313
    • Chari, D.M.1    Blakemore, W.F.2
  • 7
    • 2942554826 scopus 로고    scopus 로고
    • NB-3/Notch1 pathway via Deltex1 promotes neural progenitor cell differentiation into oligodendrocytes
    • Cui X. Y., Hu Q. D., Tekaya M., et al,. (2004) NB-3/Notch1 pathway via Deltex1 promotes neural progenitor cell differentiation into oligodendrocytes. J. Biol. Chem. 279, 25858-25865.
    • (2004) J. Biol. Chem. , vol.279 , pp. 25858-25865
    • Cui, X.Y.1    Hu, Q.D.2    Tekaya, M.3
  • 8
    • 0028662387 scopus 로고
    • Single intracerebral injection of apotransferrin in young rats induces increased myelination
    • Escobar Cabrera O. E., Bongarzone E. R., Soto E. F., and, Pasquini J. M., (1994) Single intracerebral injection of apotransferrin in young rats induces increased myelination. Dev. Neurosci. 16, 248-254.
    • (1994) Dev. Neurosci. , vol.16 , pp. 248-254
    • Escobar Cabrera, O.E.1    Bongarzone, E.R.2    Soto, E.F.3    Pasquini, J.M.4
  • 9
    • 0030968309 scopus 로고    scopus 로고
    • Single intracranial injection of apotransferrin in young rats increases the expression of specific myelin protein mRNA
    • Escobar Cabrera O. E., Zakin M. M., Soto E. F., and, Pasquini J. M., (1997) Single intracranial injection of apotransferrin in young rats increases the expression of specific myelin protein mRNA. J. Neurosci. Res. 47, 603-608.
    • (1997) J. Neurosci. Res. , vol.47 , pp. 603-608
    • Escobar Cabrera, O.E.1    Zakin, M.M.2    Soto, E.F.3    Pasquini, J.M.4
  • 10
    • 0342514711 scopus 로고    scopus 로고
    • Myelin membranes isolated from rats intracranially injected with apotransferrin are more susceptible to in vitro peroxidation
    • Escobar Cabrera O. E., Soto E. F., and, Pasquini J. M., (2000) Myelin membranes isolated from rats intracranially injected with apotransferrin are more susceptible to in vitro peroxidation. Neurochem. Res. 25, 87-93.
    • (2000) Neurochem. Res. , vol.25 , pp. 87-93
    • Escobar Cabrera, O.E.1    Soto, E.F.2    Pasquini, J.M.3
  • 13
    • 0036968089 scopus 로고    scopus 로고
    • Transferrin regulates transcription of the MBP gene and its action synergizes with IGF-1 to enhance myelinogenesis in the md rat
    • Espinosa-Jeffrey A., Kumar S., Zhao P. M., Awosika O., Agbo C., Huang A., Chang R., and, De Vellis J., (2002) Transferrin regulates transcription of the MBP gene and its action synergizes with IGF-1 to enhance myelinogenesis in the md rat. Dev. Neurosci. 24, 227-241.
    • (2002) Dev. Neurosci. , vol.24 , pp. 227-241
    • Espinosa-Jeffrey, A.1    Kumar, S.2    Zhao, P.M.3    Awosika, O.4    Agbo, C.5    Huang, A.6    Chang, R.7    De Vellis, J.8
  • 14
    • 0036720034 scopus 로고    scopus 로고
    • Why does remyelination fail in multiple sclerosis?
    • Franklin R. J., (2002) Why does remyelination fail in multiple sclerosis? Nat. Rev. Neurosci. 3, 705-714.
    • (2002) Nat. Rev. Neurosci. , vol.3 , pp. 705-714
    • Franklin, R.J.1
  • 15
    • 54249124952 scopus 로고    scopus 로고
    • Remyelination in the CNS: From biology to therapy
    • Franklin R. J., and, Ffrench-Constant C., (2008) Remyelination in the CNS: from biology to therapy. Nat. Rev. Neurosci. 9, 839-855.
    • (2008) Nat. Rev. Neurosci. , vol.9 , pp. 839-855
    • Franklin, R.J.1    Ffrench-Constant, C.2
  • 16
    • 62749122684 scopus 로고    scopus 로고
    • Transcription factor RBP-J-mediated signaling represses the differentiation of neural stem cells into intermediate neural progenitors
    • Gao F., Zhang Q., Zheng M. H., et al,. (2009) Transcription factor RBP-J-mediated signaling represses the differentiation of neural stem cells into intermediate neural progenitors. Mol. Cell. Neurosci. 40, 442-450.
    • (2009) Mol. Cell. Neurosci. , vol.40 , pp. 442-450
    • Gao, F.1    Zhang, Q.2    Zheng, M.H.3
  • 17
    • 0036802264 scopus 로고    scopus 로고
    • Development of nodes of Ranvier
    • Girault J. A., and, Peles E., (2002) Development of nodes of Ranvier. Curr. Opin. Neurobiol. 12, 476-485.
    • (2002) Curr. Opin. Neurobiol. , vol.12 , pp. 476-485
    • Girault, J.A.1    Peles, E.2
  • 18
    • 10744233414 scopus 로고    scopus 로고
    • F3/contactin acts as a functional ligand for Notch during oligodendrocyte maturation
    • Hu Q. D., Ang B. T., Karsak M., et al,. (2003) F3/contactin acts as a functional ligand for Notch during oligodendrocyte maturation. Cell 115, 163-175.
    • (2003) Cell , vol.115 , pp. 163-175
    • Hu, Q.D.1    Ang, B.T.2    Karsak, M.3
  • 19
    • 0031050183 scopus 로고    scopus 로고
    • Locomotor deficits induced by experimental spinal cord demyelination are abolished by spontaneous remyelination
    • Jeffery N. D., and, Blakemore W. F., (1997) Locomotor deficits induced by experimental spinal cord demyelination are abolished by spontaneous remyelination. Brain 120 (Pt 1), 27-37.
    • (1997) Brain , vol.120 , Issue.PART 1 , pp. 27-37
    • Jeffery, N.D.1    Blakemore, W.F.2
  • 20
    • 0036799650 scopus 로고    scopus 로고
    • Multiple sclerosis: Re-expression of a developmental pathway that restricts oligodendrocyte maturation
    • John G. R., Shankar S. L., Shafit-Zagardo B., Massimi A., Lee S. C., Raine C. S., and, Brosnan C. F., (2002) Multiple sclerosis: re-expression of a developmental pathway that restricts oligodendrocyte maturation. Nat. Med. 8, 1115-1121.
    • (2002) Nat. Med. , vol.8 , pp. 1115-1121
    • John, G.R.1    Shankar, S.L.2    Shafit-Zagardo, B.3    Massimi, A.4    Lee, S.C.5    Raine, C.S.6    Brosnan, C.F.7
  • 21
    • 37849014948 scopus 로고    scopus 로고
    • Overcoming failure to repair demyelination in EAE: Gamma-secretase inhibition of Notch signaling
    • Jurynczyk M., Jurewicz A., Bielecki B., Raine C. S., and, Selmaj K., (2008) Overcoming failure to repair demyelination in EAE: gamma-secretase inhibition of Notch signaling. J. Neurol. Sci. 265, 5-11.
    • (2008) J. Neurol. Sci. , vol.265 , pp. 5-11
    • Jurynczyk, M.1    Jurewicz, A.2    Bielecki, B.3    Raine, C.S.4    Selmaj, K.5
  • 22
    • 0019207394 scopus 로고
    • Gliogenesis of astrocytes and oligodendrocytes in the neocortical grey and white matter of the adult rat: Electron microscopic analysis of light radioautographs
    • Kaplan M. S., and, Hinds J. W., (1980) Gliogenesis of astrocytes and oligodendrocytes in the neocortical grey and white matter of the adult rat: electron microscopic analysis of light radioautographs. J. Comp. Neurol. 193, 711-727.
    • (1980) J. Comp. Neurol. , vol.193 , pp. 711-727
    • Kaplan, M.S.1    Hinds, J.W.2
  • 23
    • 0026331351 scopus 로고
    • Study of the transformation of amoeboid microglial cells into microglia labelled with the isolectin Griffonia simplicifolia in postnatal rats
    • Kaur C., and, Ling E. A., (1991) Study of the transformation of amoeboid microglial cells into microglia labelled with the isolectin Griffonia simplicifolia in postnatal rats. Acta Anat. 142, 118-125.
    • (1991) Acta Anat. , vol.142 , pp. 118-125
    • Kaur, C.1    Ling, E.A.2
  • 24
    • 64249172203 scopus 로고    scopus 로고
    • The canonical Notch signaling pathway: Unfolding the activation mechanism
    • Kopan R., and, Ilagan M. X., (2009) The canonical Notch signaling pathway: unfolding the activation mechanism. Cell 137, 216-233.
    • (2009) Cell , vol.137 , pp. 216-233
    • Kopan, R.1    Ilagan, M.X.2
  • 25
    • 11844253894 scopus 로고    scopus 로고
    • Macrophage-depletion induced impairment of experimental CNS remyelination is associated with a reduced oligodendrocyte progenitor cell response and altered growth factor expression
    • Kotter M. R., Zhao C., van Rooijen N., and, Franklin R. J., (2005) Macrophage-depletion induced impairment of experimental CNS remyelination is associated with a reduced oligodendrocyte progenitor cell response and altered growth factor expression. Neurobiol. Dis. 18, 166-175.
    • (2005) Neurobiol. Dis. , vol.18 , pp. 166-175
    • Kotter, M.R.1    Zhao, C.2    Van Rooijen, N.3    Franklin, R.J.4
  • 26
    • 30644476095 scopus 로고    scopus 로고
    • Myelin impairs CNS remyelination by inhibiting oligodendrocyte precursor cell differentiation
    • Kotter M. R., Li W. W., Zhao C., and, Franklin R. J., (2006) Myelin impairs CNS remyelination by inhibiting oligodendrocyte precursor cell differentiation. J. Neurosci. 26, 328-332.
    • (2006) J. Neurosci. , vol.26 , pp. 328-332
    • Kotter, M.R.1    Li, W.W.2    Zhao, C.3    Franklin, R.J.4
  • 27
    • 0030222037 scopus 로고    scopus 로고
    • Microglia: A sensor for pathological events in the CNS
    • Kreutzberg G. W., (1996) Microglia: a sensor for pathological events in the CNS. Trends Neurosci. 19, 312-318.
    • (1996) Trends Neurosci. , vol.19 , pp. 312-318
    • Kreutzberg, G.W.1
  • 28
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli U. K., (1970) Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227, 680-685.
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 29
    • 33947509525 scopus 로고    scopus 로고
    • The immunopathology of multiple sclerosis: An overview
    • Lassmann H., Bruck W., and, Lucchinetti C. F., (2007) The immunopathology of multiple sclerosis: an overview. Brain Pathol. 17, 210-218.
    • (2007) Brain Pathol. , vol.17 , pp. 210-218
    • Lassmann, H.1    Bruck, W.2    Lucchinetti, C.F.3
  • 30
    • 33748420494 scopus 로고    scopus 로고
    • Effects of commissural de- and remyelination on motor skill behaviour in the cuprizone mouse model of multiple sclerosis
    • Liebetanz D., and, Merkler D., (2006) Effects of commissural de- and remyelination on motor skill behaviour in the cuprizone mouse model of multiple sclerosis. Exp. Neurol. 202, 217-224.
    • (2006) Exp. Neurol. , vol.202 , pp. 217-224
    • Liebetanz, D.1    Merkler, D.2
  • 31
    • 0018234553 scopus 로고
    • Central nervous system demyelination and remyelination in the mouse: An ultrastructural study of cuprizone toxicity
    • Ludwin S. K., (1978) Central nervous system demyelination and remyelination in the mouse: an ultrastructural study of cuprizone toxicity. Lab. Invest. 39, 597-612.
    • (1978) Lab. Invest. , vol.39 , pp. 597-612
    • Ludwin, S.K.1
  • 32
    • 0036023380 scopus 로고    scopus 로고
    • Notch1 is required for neuronal and glial differentiation in the cerebellum
    • Lutolf S., Radtke F., Aguet M., Suter U., and, Taylor V., (2002) Notch1 is required for neuronal and glial differentiation in the cerebellum. Development 129, 373-385.
    • (2002) Development , vol.129 , pp. 373-385
    • Lutolf, S.1    Radtke, F.2    Aguet, M.3    Suter, U.4    Taylor, V.5
  • 34
    • 0035198691 scopus 로고    scopus 로고
    • The neurotoxicant, cuprizone, as a model to study demyelination and remyelination in the central nervous system
    • Matsushima G. K., and, Morell P., (2001) The neurotoxicant, cuprizone, as a model to study demyelination and remyelination in the central nervous system. Brain Pathol. 11, 107-116.
    • (2001) Brain Pathol. , vol.11 , pp. 107-116
    • Matsushima, G.K.1    Morell, P.2
  • 35
    • 0023912069 scopus 로고
    • Radioautographic evidence for slow astrocyte turnover and modest oligodendrocyte production in the corpus callosum of adult mice infused with 3H-thymidine
    • McCarthy G. F., and, Leblond C. P., (1988) Radioautographic evidence for slow astrocyte turnover and modest oligodendrocyte production in the corpus callosum of adult mice infused with 3H-thymidine. J. Comp. Neurol. 271, 589-603.
    • (1988) J. Comp. Neurol. , vol.271 , pp. 589-603
    • McCarthy, G.F.1    Leblond, C.P.2
  • 36
    • 35548986727 scopus 로고    scopus 로고
    • Dissecting demyelination
    • Miller R. H., and, Mi S., (2007) Dissecting demyelination. Nat. Neurosci. 10, 1351-1354.
    • (2007) Nat. Neurosci. , vol.10 , pp. 1351-1354
    • Miller, R.H.1    Mi, S.2
  • 37
    • 84883454794 scopus 로고    scopus 로고
    • M2 microglia and macrophages drive oligodendrocyte differentiation during CNS remyelination
    • Miron V. E., Boyd A., Zhao J. W., et al,. (2013) M2 microglia and macrophages drive oligodendrocyte differentiation during CNS remyelination. Nat. Neurosci. 16, 1211-1218.
    • (2013) Nat. Neurosci. , vol.16 , pp. 1211-1218
    • Miron, V.E.1    Boyd, A.2    Zhao, J.W.3
  • 38
    • 34548204310 scopus 로고    scopus 로고
    • Transcriptional control of oligodendrogenesis
    • Nicolay D. J., Doucette J. R., and, Nazarali A. J., (2007) Transcriptional control of oligodendrogenesis. Glia 55, 1287-1299.
    • (2007) Glia , vol.55 , pp. 1287-1299
    • Nicolay, D.J.1    Doucette, J.R.2    Nazarali, A.J.3
  • 39
    • 0027412343 scopus 로고
    • Condensation of the chromatin at the membrane of an apoptotic nucleus is not associated with activation of an endonuclease
    • Oberhammer F., Fritsch G., Schmied M., Pavelka M., Printz D., Purchio T., Lassmann H., and, Schulte-Hermann R., (1993) Condensation of the chromatin at the membrane of an apoptotic nucleus is not associated with activation of an endonuclease. J. Cell Sci. 104 (Pt 2), 317-326.
    • (1993) J. Cell Sci. , vol.104 , Issue.PART 2 , pp. 317-326
    • Oberhammer, F.1    Fritsch, G.2    Schmied, M.3    Pavelka, M.4    Printz, D.5    Purchio, T.6    Lassmann, H.7    Schulte-Hermann, R.8
  • 40
    • 0041508452 scopus 로고    scopus 로고
    • Delta-Notch signaling regulates oligodendrocyte specification
    • Park H. C., and, Appel B., (2003) Delta-Notch signaling regulates oligodendrocyte specification. Development 130, 3747-3755.
    • (2003) Development , vol.130 , pp. 3747-3755
    • Park, H.C.1    Appel, B.2
  • 41
    • 0018410045 scopus 로고
    • Remyelination in multiple sclerosis
    • Prineas J. W., and, Connell F., (1979) Remyelination in multiple sclerosis. Ann. Neurol. 5, 22-31.
    • (1979) Ann. Neurol. , vol.5 , pp. 22-31
    • Prineas, J.W.1    Connell, F.2
  • 42
    • 0034465730 scopus 로고    scopus 로고
    • Bidirectional signaling between neurons and glial cells via the F3 neuronal adhesion molecule
    • Revest J. M., Faivre-Sarrailh C., Schachner M., and, Rougon G., (1999) Bidirectional signaling between neurons and glial cells via the F3 neuronal adhesion molecule. Adv. Exp. Med. Biol. 468, 309-318.
    • (1999) Adv. Exp. Med. Biol. , vol.468 , pp. 309-318
    • Revest, J.M.1    Faivre-Sarrailh, C.2    Schachner, M.3    Rougon, G.4
  • 43
    • 2342513503 scopus 로고    scopus 로고
    • Glial specification in the vertebrate neural tube
    • Rowitch D. H., (2004) Glial specification in the vertebrate neural tube. Nat. Rev. Neurosci. 5, 409-419.
    • (2004) Nat. Rev. Neurosci. , vol.5 , pp. 409-419
    • Rowitch, D.H.1
  • 45
    • 0038248966 scopus 로고    scopus 로고
    • Myelination and motor coordination are increased in transferrin transgenic mice
    • Saleh M. C., Espinosa de los Monteros A., de Arriba Zerpa G. A., et al,. (2003) Myelination and motor coordination are increased in transferrin transgenic mice. J. Neurosci. Res. 72, 587-594.
    • (2003) J. Neurosci. Res. , vol.72 , pp. 587-594
    • Saleh, M.C.1    Espinosa De Los Monteros, A.2    De Arriba Zerpa, G.A.3
  • 46
    • 0014469463 scopus 로고
    • Status spongiosus of CNS and hepatic changes induced by cuprizone (biscyclohexanone oxalyldihydrazone)
    • Suzuki K., and, Kikkawa Y., (1969) Status spongiosus of CNS and hepatic changes induced by cuprizone (biscyclohexanone oxalyldihydrazone). Am. J. Pathol. 54, 307-325.
    • (1969) Am. J. Pathol. , vol.54 , pp. 307-325
    • Suzuki, K.1    Kikkawa, Y.2
  • 47
    • 37549016046 scopus 로고    scopus 로고
    • Regulation of Notch signaling by dynamic changes in the precision of S3 cleavage of Notch-1
    • Tagami S., Okochi M., Yanagida K., et al,. (2008) Regulation of Notch signaling by dynamic changes in the precision of S3 cleavage of Notch-1. Mol. Cell. Biol. 28, 165-176.
    • (2008) Mol. Cell. Biol. , vol.28 , pp. 165-176
    • Tagami, S.1    Okochi, M.2    Yanagida, K.3
  • 48
    • 34447517526 scopus 로고    scopus 로고
    • Physiological Notch signaling promotes gliogenesis in the developing peripheral and central nervous systems
    • Taylor M. K., Yeager K., and, Morrison S. J., (2007) Physiological Notch signaling promotes gliogenesis in the developing peripheral and central nervous systems. Development 134, 2435-2447.
    • (2007) Development , vol.134 , pp. 2435-2447
    • Taylor, M.K.1    Yeager, K.2    Morrison, S.J.3
  • 50
    • 0028928684 scopus 로고
    • Oligodendrocytes originate in a restricted zone of the embryonic ventral neural tube defined by DM-20 mRNA expression
    • Timsit S., Martinez S., Allinquant B., Peyron F., Puelles L., and, Zalc B., (1995) Oligodendrocytes originate in a restricted zone of the embryonic ventral neural tube defined by DM-20 mRNA expression. J. Neurosci. 15, 1012-1024.
    • (1995) J. Neurosci. , vol.15 , pp. 1012-1024
    • Timsit, S.1    Martinez, S.2    Allinquant, B.3    Peyron, F.4    Puelles, L.5    Zalc, B.6
  • 52
    • 0026014668 scopus 로고
    • Evidence for the ventral origin of oligodendrocyte precursors in the rat spinal cord
    • Warf B. C., Fok-Seang J., and, Miller R. H., (1991) Evidence for the ventral origin of oligodendrocyte precursors in the rat spinal cord. J. Neurosci. 11, 2477-2488.
    • (1991) J. Neurosci. , vol.11 , pp. 2477-2488
    • Warf, B.C.1    Fok-Seang, J.2    Miller, R.H.3
  • 53
    • 0029978087 scopus 로고    scopus 로고
    • Distinct effects of recombinant tenascin-R domains in neuronal cell functions and identification of the domain interacting with the neuronal recognition molecule F3/11
    • Xiao Z. C., Taylor J., Montag D., Rougon G., and, Schachner M., (1996) Distinct effects of recombinant tenascin-R domains in neuronal cell functions and identification of the domain interacting with the neuronal recognition molecule F3/11. Eur. J. Neurosci. 8, 766-782.
    • (1996) Eur. J. Neurosci. , vol.8 , pp. 766-782
    • Xiao, Z.C.1    Taylor, J.2    Montag, D.3    Rougon, G.4    Schachner, M.5


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