Myelination and motor coordination are increased in transferrin transgenic mice

Journal of Neuroscience Research

Volumn 72, Issue 5, 2003, Pages 587-594

  Saleh, Maria Carla ^a   Espinosa De los Monteros, Araceli ^b   De Arriba Zerpa, Gonzalo A ^a   Fontaine, Isabelle ^c   Piaud, Oriane ^a   Djordjijevic, Dragan ^a   Baroukh, Nadine ^a   Garcia Otin, Angel Luis ^a   Ortiz, Esteban ^d   Lewis, Sandra ^e   Fiette, Laurence ^a   Santambrogio, Paolo ^f   Belzung, Catherine ^e   Connor, James R ^g   De Vellis, Jean ^b   Pasquini, Juana M ^d   Zakin, Mario M ^a   Baron, Bruno ^a   Guillou, Florian ^c  

^a INSTITUT PASTEUR   (France)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c CNRS   (France)

^d UNIVERSIDAD DE BUENOS AIRES   (Argentina)

^e UNIVERSITÉ DE TOURS   (France)

^f SAN RAFFAELE HOSPITAL   (Italy)

^g PENN STATE COLLEGE OF MEDICINE   (United States)

Author keywords

Central nervous system; Myelin deficiency; Transferrin

Indexed keywords

COMPLEMENTARY DNA; MYELIN; PHOSPHOLIPID; TRANSFERRIN;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; GENE OVEREXPRESSION; IN SITU HYBRIDIZATION; MOTOR COORDINATION; MOUSE; MYELIN DEFICIENCY; MYELINATION; NONHUMAN; PRIORITY JOURNAL; TRANSGENIC MOUSE;

ANIMALS; AXONS; CELL DIFFERENTIATION; CELL DIVISION; CENTRAL NERVOUS SYSTEM; DEMYELINATING DISEASES; GAIT DISORDERS, NEUROLOGIC; GALACTOLIPIDS; HUMANS; MICE; MICE, TRANSGENIC; MICROSCOPY, ELECTRON; MOVEMENT; MYELIN PROTEINS; MYELIN SHEATH; OLIGODENDROGLIA; PHOSPHOLIPIDS; TRANSFERRIN; TRANSGENES; UP-REGULATION;

EID: 0038248966     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/jnr.10619     Document Type: Article

References (43)

1. Adlkofer K, Martini R, Aguzzi A, Zielasek J, Toyka KV, Suter U. 1995. Hypermyelination and demyelinating peripheral neuropathy in Pmp22-deficient mice. Nat Genet 11:274-280.
2. Barcellos-Hoff MH, Aggeler J, Ram TG, Bissell MJ. 1989. Functional differentiation and alveolar morphogenesis of primary mammary cultures on reconstituted basement membrane. Development 105:223-235.
3. Bartlett WP, Li XS, Connor JR. 1991. Expression of transferrin mRNA in the CNS of normal and jimpy mice. J Neurochem 57:318-322.
4. Bizzozero OA, Bixler HA, Davis JD, Espinosa A, Messier AM. 2001. Chemical deacylation reduces the adhesive properties of proteolipid protein and leads to decompaction of the myelin sheath. J Neurochem 76:1129-1141.
5. Bloch B, Popovici T, Levin MJ, Tuil D, Kahn A. 1985. Transferrin gene expression visualized in oligodendrocytes of the rat brain by using in situ hybridization and immunohistochemistry. Proc Natl Acad Sci USA 82:6706-6710.
6. Carson JH, Nielson ML, Barbarese E. 1983. Developmental regulation of myelin basic protein expression in mouse brain. Dev Biol 96:485-492.
7. Carson MJ, Behringer RR, Brinster RL, McMorris FA. 1993. Insulin-like growth factor I increases brain growth and central nervous system myelination in transgenic mice. Neuron 10:729-740.
8. Cassia R, Besnard L, Fiette L, Espinosa de los Monteros A, Ave P, Py MC, Huerre M, de Vellis J, Zakin MM, Guillou F. 1997. Transferrin is an early marker of hepatic differentiation, and its expression correlates with the postnatal development of oligodendrocytes in mice. J Neurosci Res 50:421-432.
9. Chen PSJ, Toribara T, Warner H. 1956. Microdetermination of phosphorus. Anal Chem 28:1756-1758.
10. Connor JR, Roskams AJ, Menzies SL, Williams ME. 1993. Transferrin in the central nervous system of the shiverer mouse myelin mutant. J Neurosci Res 36:501-507.
11. Connor JR, Menzies SL, Burdo JR, Boyer PJ. 2001. Iron and iron management proteins in neurobiology. Pediatr Neurol 25:118-129.
12. de Arriba Zerpa GA, Saleh MC, Fernandez PM, Guillou F, Espinosa de Los Monteros A, de Vellis J, Zakin MM, Baron B. 2000. Alternative splicing prevents transferrin secretion during differentiation of a human oligodendrocyte cell line. J Neurosci Res 61:388-395.
13. Dickinson TK, Connor JR. 1994. Histological analysis of selected brain regions of hypotransferrinemic mice. Brain Res 635:169-178.
14. Duchange N, Saleh M-C, de Arriba Zerpa G, Pidoux J, Guillou F, Zakin MM, Baron B. 2002. Alternative splicing in the brain of mice and rats generates transferrin transcripts lacking, as in humans, the signal peptide sequence. Neurochem Res 27:1459-1463.
15. Escobar Cabrera OE, Bongarzone ER, Soto EF, Pasquini JM. 1994. Single intracerebral injection of apotransferrin in young rats induces increased myelination. Dev Neurosci 16:248-254.
16. Escobar Cabrera OE, Zakin MM, Soto EF, Pasquini JM. 1997. Single intracranial injection of apotransferrin in young rats increases the expression of specific myelin protein mRNA. J Neurosci Res 47:603-608.
17. Espinosa de los Monteros A, Kumar S, Zhao P, Huang CJ, Nazarian R, Pan T, Scully S, Chang R, de Vellis J. 1999. Transferrin is an essential factor for myelination. Neurochem Res 24:235-248.
18. Folch PJ, Lees M, Sloane-Stanley G. 1957. A simple method for isolation and purification of total lipids from animal tissues. J Biol Chem 226:499-509.
19. Gocht A, Keith AB, Candy JM, Morris CM. 1993. Iron uptake in the brain of the myelin-deficient rat. Neurosci Lett 154:187-190.
20. Hess HH, Lewin E. 1965. Microassay of biochemical structural components in nervous tissue. II Method for cerebroside, proteolipids proteins and residue proteins. J Neurochem 12:205-211.
21. Hulet SW, Heyliger SO, Powers S, Connor JR. 2000. Oligodendrocyte progenitor cells internalize ferritin via clathrin-dependent receptor mediated endocytosis. J Neurosci Res 61:52-60.
22. Itoh T, Reddy UR, Stern JL, Chen M, Itoh A, Pleasure D. 2000. Diminished calcium homeostasis and increased susceptibility to excitotoxicity of JS 3/16 progenitor cells after differentiation to oligodendroglia. Glia 31:165-180.
23. Laemmli UK. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680-685.
24. Lalonde R, Botez MI, Joyal CC, Caumartin M. 1992. Motor abnormalities in lurcher mutant mice. Physiol Behav 51:523-525.
25. Lees MB, Paxman S. 1972. Modification of the Lowry procedure for the analysis of proteolipid protein. Anal Biochem 47:184-192.
26. Le Magueresse B, Pineau C, Guillou F, Jegou B. 1988. Influence of germ cells upon transferrin secretion by rat Sertoli cells in vitro. J Endocrinol 118:R13-16.
27. Lewen A, Matz P, Chan PH. 2000. Free radical pathways in CNS injury. J Neurotrauma 17:871-890.
28. Marta CB, Escobar Cabrera OE, Garcia CI, Villar MJ, Pasquini JM, Soto EF. 2000. Oligodendroglial cell differentiation in rat brain is accelerated by the intracranial injection of apotransferrin. Cell Mol Biol 46:529-539.
29. Marta CB, Ortiz EH, Hallak M, Baron B, Guillou F, Zakin MM, Soto EF, Pasquini J M. 2002. Changes in the expression of cytoskeletal proteins in the CNS of transferrin transgenic mice. Dev Neurosci 24:242-251.
30. McCracken JY, Molenaar AJ, Wilkins RJ, Grigor MR. 1994. Spatial and temporal expression of transferrin gene in the rat mammary gland. J Dairy Sci 77:1828-1834.
31. Morgan EH. 1969. Factors affecting the synthesis of transferrin by rat tissue slices. J Biol Chem 244:4193-4199.
32. Norton WT, Poduslo SE. 1973. Myelination in rat brain: method of myelin isolation. J Neurochem 21:749-757.
33. Readhead C, Schneide A, Griffiths I, Nave KA. 1994. Premature arrest of myelin formation in transgenic mice with increased proteolipid protein gene dosage. Neuron 12:583-595.
34. Sambrook J, Fritsch EF, Maniatis T. 1989 Molecular cloning: a laboratory manual. New York: Cold Spring Harbor Laboratory Press.
35. Santambrogio P, Cozzi A, Levi S, Rovida E, Magni F, Albertini A, Arosio P. 2000. Functional and immunological analysis of recombinant mouse H- and L-ferritins from Escherichia coli. Protein Expr Purif 19:212-218.
36. Searcy R, Bergquis LM. 1960. A new color reaction for the quantitation of serum cholesterol. Clin Chim Acta 1960:192-199.
37. Skinner MK, Griswold MD. 1980. Sertoli cells synthesize and secrete transferrin-like protein. J Biol Chem 255:9523-9525.
38. Storch S, Kubler B, Honing S, Ackmann M, Zapf J, Blum W, Braulke T. 2001. Transferrin binds insulin-like growth factors and affects binding properties of insulin-like growth factor binding protein-3. FEBS Lett 509:395-398.
39. Suter U, Nave KA. 1999. Transgenic mouse models of CMT1A and HNPP. Ann NY Acad Sci 883:247-253.
40. Tu GF, Achen MG, Aldred AR, Southwell BR, Schreiber G. 1991. The distribution of cerebral expression of the transferrin gene is species specific. J Biol Chem 266:6201-6208.
41. Weinzimer SA, Gibson TB, Collett-Solberg PF, Khare A, Liu B, Cohen P. 2001. Transferrin is an insulin-like growth factor-binding protein-3 binding protein. J Clin Endocrinol Metab 86:1806-1813.
42. Wrabetz L, Feltri ML, Quattrini A, Imperiale D, Previtali S, D'Antonio M, Martini R, Yin X, Trapp BD, Zhou L, Chiu SY, Messing A. 2000. P(0) glycoprotein overexpression causes congenital hypomyelination of peripheral nerves. J Cell Biol 148:1021-1034.
43. Yin X, Peterson J, Gravel M, Braun PE, Trapp BD. 1997. CNP overexpression induces aberrant oligodendrocyte membranes and inhibits MBP accumulation and myelin compaction. J Neurosci Res 50:238-247.