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Volumn 24, Issue 2, 1999, Pages 235-248

Transferrin is an essential factor for myelination

Author keywords

Iron metabolism; Myelin; Oligodendrocytes; Transferrin

Indexed keywords

APOTRANSFERRIN; MESSENGER RNA; MYELIN; MYELIN BASIC PROTEIN; PROTEOLIPID PROTEIN; TRANSFERRIN;

EID: 0032959995     PISSN: 03643190     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11064-004-1826-2     Document Type: Article
Times cited : (79)

References (36)
  • 1
    • 85121067886 scopus 로고    scopus 로고
    • 1. I.D. Duncan 1995 Inherited disorders of myelination of the central nervous system B.R. Ransom Neuroglial Cells HR Kettenman New York 990 1009 Duncan I.D. 1995. Inherited disorders of myelination of the central nervous system. Pages 990–1009, in Ransom, B.R. (ed), Neuroglial Cells, HR Kettenman, New York.
  • 2
    • 85121075860 scopus 로고    scopus 로고
    • 2. A. Espinosa de los Monteros J. de Vellis 1995 Vulnerability of oligodendrocytes to environmental insults: potential for recovery M. Aschner H. K. Kimelberg The Role of Glia in Neurotoxicology CRC Press, New York 15 40 Espinosa de los Monteros, A. and de Vellis, J. 1995. Vulnerability of oligodendrocytes to environmental insults: potential for recovery. Pages 15–40, in Aschner, M. and Kimelberg, H. K., (eds.), The Role of Glia in Neurotoxicology, CRC Press, New York.
  • 3
    • 0028122616 scopus 로고
    • Neurological mouse mutants and the genes of myelin
    • 3. K.A. Nave 1994 Neurological mouse mutants and the genes of myelin J. Neurosci. Res. 38 607 612 7807578 Nave, K.A. 1994. Neurological mouse mutants and the genes of myelin. J. Neurosci. Res. 38:607–612.
    • (1994) J. Neurosci. Res. , vol.38 , pp. 607-612
    • Nave, K.A.1
  • 4
    • 0028133486 scopus 로고
    • Glial cell degeneration and hypomyelination caused by overexpression of myelin proteolipid protein gene
    • 4. T. Kagawa K. Ikenaka Y. Inowe S. Kuriyama T. Tsijii J. Nakao K. Nakajima J. Aruga H. Okano K. Mikoshiba 1994 Glial cell degeneration and hypomyelination caused by overexpression of myelin proteolipid protein gene Neuron. 13 427 442 7520255 Kagawa, T., Ikenaka, K., Inowe, Y., Kuriyama, Sh., Tsijii, T., Nakao, J., Nakajima, K., Aruga, J., Okano, H. and Mikoshiba, K. 1994. Glial cell degeneration and hypomyelination caused by overexpression of myelin proteolipid protein gene. Neuron. 13:427–442.
    • (1994) Neuron. , vol.13 , pp. 427-442
    • Kagawa, T.1    Ikenaka, K.2    Inowe, Y.3    Kuriyama, S.4    Tsijii, T.5    Nakao, J.6    Nakajima, K.7    Aruga, J.8    Okano, H.9    Mikoshiba, K.10
  • 5
    • 85121081744 scopus 로고    scopus 로고
    • 5. R.H. Quarles 1988 Myelin-associated glycoprotein functional and clinical aspects P. J. Marangos I. Campbell R.M. Cohen Neurobiological Research, Vol. II: Neuronal and Glial Proteins Structure, Function, and Clinical Application Academic New York 295 320 Quarles, R.H. (1988). Myelin-associated glycoprotein functional and clinical aspects. Pages 295–320, in Marangos, P. J., Campbell, I. and Cohen, R.M. (eds.), Neurobiological Research, Vol. II: Neuronal and Glial Proteins Structure, Function, and Clinical Application, Academic, New York.
  • 6
    • 0018394196 scopus 로고
    • Myelin deficient (md): A neurologic mutant in the Wistar rat
    • 6. C.K. Csiza A. de Lahunta 1979 Myelin deficient (md): A neurologic mutant in the Wistar rat Am. J. Pathol. 95 215 219 434110 Csiza, C.K. and de Lahunta, A. 1979. Myelin deficient (md): A neurologic mutant in the Wistar rat. Am. J. Pathol. 95:215–219.
    • (1979) Am. J. Pathol. , vol.95 , pp. 215-219
    • Csiza, C.K.1    de Lahunta, A.2
  • 7
    • 0024430148 scopus 로고
    • Myelin-deficient rat: A point mutation in exon III (A—C, Thr 75—Pro) of the myelin proteo-lipid protein causes dysmyelination and oligodendrocyte death
    • 7. D. Boison W. Stoffel 1989 Myelin-deficient rat: A point mutation in exon III (A—C, Thr 75—Pro) of the myelin proteo-lipid protein causes dysmyelination and oligodendrocyte death Embo. Journal. 8 3295 3302 2479544 Boison, D. and Stoffel, W. 1989. Myelin-deficient rat: A point mutation in exon III (A—C, Thr 75—Pro) of the myelin proteo-lipid protein causes dysmyelination and oligodendrocyte death. Embo. Journal. 8:3295–3302.
    • (1989) Embo. Journal. , vol.8 , pp. 3295-3302
    • Boison, D.1    Stoffel, W.2
  • 8
    • 0025258937 scopus 로고
    • Transcriptional regulation studies of myelin-associated genes in myelin-deficient rats
    • 8. S. Kumar W.B. Macklin M.N. Gordon A. Espinosa de los Monteros R. Cole S. A. Scully J. de Vellis 1990 Transcriptional regulation studies of myelin-associated genes in myelin-deficient rats Developmental Neuroscience 12 316 325 1705212 Kumar, S., Macklin, W.B., Gordon, M.N., Espinosa de los Monteros A., Cole, R., Scully, S. A., de Vellis, J. 1990. Transcriptional regulation studies of myelin-associated genes in myelin-deficient rats. Developmental Neuroscience. 12:316–325.
    • (1990) Developmental Neuroscience , vol.12 , pp. 316-325
    • Kumar, S.1    Macklin, W.B.2    Gordon, M.N.3    Espinosa de los Monteros, A.4    Cole, R.5    Scully, S.A.6    de Vellis, J.7
  • 9
    • 0024433128 scopus 로고
    • Does transferrin have a special role in the nervous system?
    • 9. A. Espinosa de los Monteros L.A. Pena J. de Vellis 1989 Does transferrin have a special role in the nervous system? J. Neurosci. Res. 24 125 136 2685335 Espinosa de los Monteros, A., Pena, L.A., and de Vellis, J. 1989. Does transferrin have a special role in the nervous system? J. Neurosci. Res. 24:125–136.
    • (1989) J. Neurosci. Res. , vol.24 , pp. 125-136
    • Espinosa de los Monteros, A.1    Pena, L.A.2    de Vellis, J.3
  • 10
    • 85121087068 scopus 로고    scopus 로고
    • 10. A. Espinosa de los Monteros J. de Vellis 1993 Transferrin and the developing nervous system I.S. Zagon P.J. McLaughlin Receptors in the Developing Nervous System Chapman & Hall Ltd. London 63 81 Espinosa de los Monteros, A. and de Vellis, J. 1993. Transferrin and the developing nervous system. Pages 63–81, in Zagon, I.S., and McLaughlin, P.J., (eds.) Receptors in the Developing Nervous System, Vols. 1 and 2, Chapman & Hall Ltd., London.
  • 11
    • 0022508973 scopus 로고
    • The distribution of transferring immunoreactivity in the rat nervous system
    • 11. J.R. Connor R. Fine 1986 The distribution of transferring immunoreactivity in the rat nervous system Brain Research 368 319 328 3697729 Connor, J.R. and Fine, R. 1986. The distribution of transferring immunoreactivity in the rat nervous system. Brain Research. 368: 319–328.
    • (1986) Brain Research , vol.368 , pp. 319-328
    • Connor, J.R.1    Fine, R.2
  • 12
    • 0023140776 scopus 로고
    • Development of transferrin-positive oligodendrocytes in the rat CNS
    • 12. J.R. Connor R. Fine 1987 Development of transferrin-positive oligodendrocytes in the rat CNS Journal of Neuroscience Research 17 51 59 3573080 Connor, J.R. and Fine, R. 1987. Development of transferrin-positive oligodendrocytes in the rat CNS. Journal of Neuroscience Research. 17:51–59.
    • (1987) Journal of Neuroscience Research , vol.17 , pp. 51-59
    • Connor, J.R.1    Fine, R.2
  • 13
    • 0041792815 scopus 로고
    • Transferrin gene expression visualized in oligodendrocytes of the rat brain by using in situ hybridization and immunohistochemistry
    • 13. B. Bloch T. Popovici M.J. Levin D. Tuil A. Khan 1985 Transferrin gene expression visualized in oligodendrocytes of the rat brain by using in situ hybridization and immunohistochemistry Proceedings of the National Academy of Sciences 82 6706 6710 Bloch, B., Popovici, T., Levin, M.J., Tuil, D., and Khan, A. 1985. Transferrin gene expression visualized in oligodendrocytes of the rat brain by using in situ hybridization and immunohistochemistry. Proceedings of the National Academy of Sciences. 82:6706–6710.
    • (1985) Proceedings of the National Academy of Sciences , vol.82 , pp. 6706-6710
    • Bloch, B.1    Popovici, T.2    Levin, M.J.3    Tuil, D.4    Khan, A.5
  • 14
    • 0023319268 scopus 로고
    • Transferrin gene expression in choroid plexus of the adult rat brain
    • 14. B. Bloch T. Popovichi S. Chahman M. Levine D. Tuil A. Kahn 1987 Transferrin gene expression in choroid plexus of the adult rat brain Brain Research Bulletin 18 573 576 3300864 Bloch, B., Popovichi, T., Chahman, S., Levine, M., Tuil, D. and Kahn, A. 1987. Transferrin gene expression in choroid plexus of the adult rat brain. Brain Research Bulletin. 18:573–576.
    • (1987) Brain Research Bulletin , vol.18 , pp. 573-576
    • Bloch, B.1    Popovichi, T.2    Chahman, S.3    Levine, M.4    Tuil, D.5    Kahn, A.6
  • 15
    • 0023654529 scopus 로고
    • Distribution of transferrin synthesis in brain and other tissues in the rat
    • 15. A.R. Aldred P.W. Dickson P.D. Marley G. Schreiber 1987 Distribution of transferrin synthesis in brain and other tissues in the rat J. Biol. Chem. 262 5293 5297 3558394 Aldred A.R., Dickson, P.W., Marley, P.D., and Schreiber, G. 1987. Distribution of transferrin synthesis in brain and other tissues in the rat. J. Biol. Chem. 262:5293–5297.
    • (1987) J. Biol. Chem. , vol.262 , pp. 5293-5297
    • Aldred, A.R.1    Dickson, P.W.2    Marley, P.D.3    Schreiber, G.4
  • 16
    • 0025305402 scopus 로고
    • Transferrin gene expression and secretion by rat brain cells in vitro
    • 16. A. Espinosa de los Monteros S. Kumar S.A. Scully R. Cole J. de Vellis 1990 Transferrin gene expression and secretion by rat brain cells in vitro J. Neurosci. Res. 25 576 580 2352292 Espinosa de los Monteros, A., Kumar, S., Scully, S.A., Cole, R., and de Vellis, J. 1990. Transferrin gene expression and secretion by rat brain cells in vitro. J. Neurosci. Res. 25:576–580.
    • (1990) J. Neurosci. Res. , vol.25 , pp. 576-580
    • Espinosa de los Monteros, A.1    Kumar, S.2    Scully, S.A.3    Cole, R.4    de Vellis, J.5
  • 17
    • 0019170218 scopus 로고
    • Serum-free cell culture: a unifying approach
    • 17. D. Barnes G. Sato 1980 Serum-free cell culture: a unifying approach Cell 22 649 655 7460009 Barnes, D. and Sato, G. 1980. Serum-free cell culture: a unifying approach. Cell. 22:649–655.
    • (1980) Cell , vol.22 , pp. 649-655
    • Barnes, D.1    Sato, G.2
  • 18
    • 85121087519 scopus 로고    scopus 로고
    • 18. Espinosa de los Monteros, A., Chiappelli F., Fisher, R.S., and de Vellis, J. 1988. Transferrin: An early marker of oligodendrocytes in culture. Int. J. Dev. Neurosci. 167–175.
  • 19
    • 0024231987 scopus 로고
    • Myelin-basic protein and Tf characterize distinct populations of OLs in mixed rat glial cultures
    • 19. A. Espinosa de los Monteros J. de Vellis 1988 Myelin-basic protein and Tf characterize distinct populations of OLs in mixed rat glial cultures J. Neurosci. Res. 21 181 187 2464074 Espinosa de los Monteros, A. and de Vellis, J. 1988. Myelin-basic protein and Tf characterize distinct populations of OLs in mixed rat glial cultures. J. Neurosci. Res. 21:181–187.
    • (1988) J. Neurosci. Res. , vol.21 , pp. 181-187
    • Espinosa de los Monteros, A.1    de Vellis, J.2
  • 20
    • 0025245464 scopus 로고
    • The myelin-deficient rat: partial recovery of OL maturation in vitro
    • 20. A. Espinosa de Monteros M. Zhang M.N. Gordon S. Kumar S. A. Scully J. de Vellis 1990 The myelin-deficient rat: partial recovery of OL maturation in vitro Developmental Neuroscience 12 326 339 2289414 Espinosa de Monteros A., Zhang, M., Gordon, M.N., Kumar, S., Scully, S. A., de Vellis, J. 1990. The myelin-deficient rat: partial recovery of OL maturation in vitro. Developmental Neuroscience. 12:326–339.
    • (1990) Developmental Neuroscience , vol.12 , pp. 326-339
    • Espinosa de Monteros, A.1    Zhang, M.2    Gordon, M.N.3    Kumar, S.4    Scully, S.A.5    de Vellis, J.6
  • 21
    • 4243208493 scopus 로고
    • Transferrin and central nervous system: transferrin mRNA in neuronal and glial cultures
    • 21. D. F. Condorelli G. Bonanno A. Espinosa de los Monteros J. de Vellis A.M. Giuffrida Stella 1991 Transferrin and central nervous system: transferrin mRNA in neuronal and glial cultures Ital. J. of Biochem. 40 87A 91A. Condorelli, D. F., Bonanno, G., Espinosa de los Monteros, A., de Vellis, J., and Giuffrida Stella, A.M. 1991. Transferrin and central nervous system: transferrin mRNA in neuronal and glial cultures. Ital. J. of Biochem. 40:87A–91A.
    • (1991) Ital. J. of Biochem. , vol.40 , pp. 87A-91A.
    • Condorelli, D.F.1    Bonanno, G.2    Espinosa de los Monteros, A.3    de Vellis, J.4    Giuffrida Stella, A.M.5
  • 22
    • 0028033537 scopus 로고
    • Brain-specific expression of the human transferrin gene: similar elements govern transcription in oligodendrocytes and neuronal cells
    • 22. A. Espinosa de los Monteros B.E. Sawaya F. Guillou M.M. Zakin J. de Vellis E. Schaeffer 1994 Brain-specific expression of the human transferrin gene: similar elements govern transcription in oligodendrocytes and neuronal cells J. of Biological Chem. 269 24504 24510 Espinosa de los Monteros, A., Sawaya, B.E., Guillou, F., Zakin, M.M., de Vellis, J., and Schaeffer, E. 1994. Brain-specific expression of the human transferrin gene: similar elements govern transcription in oligodendrocytes and neuronal cells. J. of Biological Chem. 269:24504–24510.
    • (1994) J. of Biological Chem. , vol.269 , pp. 24504-24510
    • Espinosa de los Monteros, A.1    Sawaya, B.E.2    Guillou, F.3    Zakin, M.M.4    de Vellis, J.5    Schaeffer, E.6
  • 23
    • 0023277545 scopus 로고
    • Single step method of RNA isolation by acid wanidium thiocyanate-phenol-chloroform extraction
    • 23. P. Chomczynski N. Sacci 1987 Single step method of RNA isolation by acid wanidium thiocyanate-phenol-chloroform extraction Anal. Biochem. 162 156 159 2440339 Chomczynski, P. and Sacci N. 1987. Single step method of RNA isolation by acid wanidium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162:156–159.
    • (1987) Anal. Biochem. , vol.162 , pp. 156-159
    • Chomczynski, P.1    Sacci, N.2
  • 24
    • 0026778299 scopus 로고
    • The Tf receptor in the Myelin Deficient (md) Rat Brain
    • 24. A.J. Roskams J.R. Connor 1992 The Tf receptor in the Myelin Deficient (md) Rat Brain J. Neurosci. Res. 31 421 427 1640494 Roskams, A.J. and Connor, J.R. 1992. The Tf receptor in the Myelin Deficient (md) Rat Brain. J. Neurosci. Res., 31:421–427, 1992.
    • (1992) J. Neurosci. Res. , vol.31 , pp. 421-427
    • Roskams, A.J.1    Connor, J.R.2
  • 25
    • 85121079011 scopus 로고    scopus 로고
    • 25. C.A. Jordan 1991 In situ hybridization in cells and tissue sections: a study of myelin gene expression during CNS myelination and remyelination M. Chesselet In Situ Hybridization Histochemistry CRC Press New York 39 70 Jordan, C.A., 1991. In situ hybridization in cells and tissue sections: a study of myelin gene expression during CNS myelination and remyelination. Pages 39–70, in Chesselet, Marie-Francoise (ed.), In Situ Hybridization Histochemistry, Chapter 3, CRC Press, New York.
  • 26
    • 0023104651 scopus 로고
    • Transferrin messenger ribonucleic acid: Molecular cloning and hormonal regulation in rat Sertoli cells
    • 26. J.L. Huggenvick R. Idzerda L. Haywood D.C. Lee G.S. McKnight M.D. Grinswold 1987 Transferrin messenger ribonucleic acid: Molecular cloning and hormonal regulation in rat Sertoli cells Endocrinology 120 332 340 3023031 Huggenvick, J.L., Idzerda, R., Haywood, L., Lee, D.C., McKnight, G.S., and Grinswold, M.D. 1987. Transferrin messenger ribonucleic acid: Molecular cloning and hormonal regulation in rat Sertoli cells. Endocrinology. 120: 332–340
    • (1987) Endocrinology , vol.120 , pp. 332-340
    • Huggenvick, J.L.1    Idzerda, R.2    Haywood, L.3    Lee, D.C.4    McKnight, G.S.5    Grinswold, M.D.6
  • 27
    • 0023280696 scopus 로고
    • Regional variation in the levels of transferrin in the CNS of normal and myelin deficient rats
    • 27. J. Connor T. Phillips M. Lakshman D. Barron R. Fine C. Csiza 1987 Regional variation in the levels of transferrin in the CNS of normal and myelin deficient rats Journal of Neurochemistry 49 5 1523 9 3312497 Connor, J., Phillips, T., Lakshman, M., Barron, D., Fine, R., and Csiza, Ch. 1987. Regional variation in the levels of transferrin in the CNS of normal and myelin deficient rats. Journal of Neurochemistry. Nov 49(5)1523–9.
    • (1987) Journal of Neurochemistry , vol.49 , Issue.5 , pp. 1523-9
    • Connor, J.1    Phillips, T.2    Lakshman, M.3    Barron, D.4    Fine, R.5    Csiza, C.6
  • 28
    • 85121080000 scopus 로고    scopus 로고
    • 28. Kumar, S., Espinosa de los Monteros, A., and de Vellis, J. 1998. Direct effect of transferrin on myelin basic protein gene expression in vivo and in cultured oligodendrocytes. In preparation.
  • 29
    • 0008204789 scopus 로고
    • What is the role of proteolipid protein in the biology of the normal and jimpy oligodendrocyte?
    • 29. R. Skoff P. Knapp 1990 What is the role of proteolipid protein in the biology of the normal and jimpy oligodendrocyte? Neurol. Neurobiol. 55 307 316 Skoff, R., and Knapp, P. 1990. What is the role of proteolipid protein in the biology of the normal and jimpy oligodendrocyte? Neurol. Neurobiol. 55:307–316.
    • (1990) Neurol. Neurobiol. , vol.55 , pp. 307-316
    • Skoff, R.1    Knapp, P.2
  • 30
    • 85121065551 scopus 로고    scopus 로고
    • 30. A. Espinosa de los Monteros J. de Vellis 1990 Oligodendrocyte differentiation: Developmental and functional subpopulations H. Althaus Cellular and Molecular Biology of Myelination Springer Verlag Berlin XX XX Espinosa de los Monteros, A. and de Vellis, J. 1990 Oligodendrocyte differentiation: Developmental and functional subpopulations. Pages XX–XX, in Althaus, H.. (ed), Cellular and Molecular Biology of Myelination, Springer Verlag, Berlin.
  • 31
    • 85121084035 scopus 로고    scopus 로고
    • 31. Espinosa de los Monteros, A. and Foucaud, B. 1987. Effect of iron and Tf on pure Ols in culture; characterization of a highaffinity Tf receptor at different ages. Developmental Brain Res. 35:123–130.
  • 32
    • 0025830995 scopus 로고
    • Thyroid hormone dependent pituitary tumor cell growth in serum-free chemically defined culture: A new regulatory role for apotransferrin
    • 32. D.A. Sirbasku R. Pakala H. Sato J.E. Eby 1991 Thyroid hormone dependent pituitary tumor cell growth in serum-free chemically defined culture: A new regulatory role for apotransferrin Biochemistry 30 7466 1854748 Sirbasku, D.A., Pakala, R., Sato, H., and Eby J.E. 1991. Thyroid hormone dependent pituitary tumor cell growth in serum-free chemically defined culture: A new regulatory role for apotransferrin. Biochemistry. 30:7466.
    • (1991) Biochemistry , vol.30 , pp. 7466
    • Sirbasku, D.A.1    Pakala, R.2    Sato, H.3    Eby, J.E.4
  • 33
    • 0026458234 scopus 로고
    • Regulation of transferrin gene expression
    • 33. M. Zakin 1992 Regulation of transferrin gene expression FASEB J. 6 3253 3258 1426763 Zakin, M. 1992. Regulation of transferrin gene expression. FASEB J. 6:3253–3258.
    • (1992) FASEB J. , vol.6 , pp. 3253-3258
    • Zakin, M.1
  • 34
    • 0028662387 scopus 로고
    • Single intracerebral injection of apotransferrin in young rats induces increased myelination
    • 34. O. Escobar E. Bongarzone E. Soto J. Pasquini 1994 Single intracerebral injection of apotransferrin in young rats induces increased myelination Dev. Neurosci. 16 248 254 7768203 Escobar, O., Bongarzone, E., Soto, E., and Pasquini J. 1994. Single intracerebral injection of apotransferrin in young rats induces increased myelination. Dev. Neurosci. 16:248–254.
    • (1994) Dev. Neurosci. , vol.16 , pp. 248-254
    • Escobar, O.1    Bongarzone, E.2    Soto, E.3    Pasquini, J.4
  • 35
    • 0030968309 scopus 로고    scopus 로고
    • Single intracranial injection of apo-transferrin in young rats increases the expression of specific myelin protein mRNA
    • 35. O.E. Escobar Cabrera M.M. Zakin E.F. Soto J.M. Pasquini 1997 Single intracranial injection of apo-transferrin in young rats increases the expression of specific myelin protein mRNA Journal of Neuroscience Research 47 6 603 8 9089208 Escobar Cabrera, O.E., Zakin, M.M., Soto, E.F., and Pasquini, J.M. 1997. Single intracranial injection of apo-transferrin in young rats increases the expression of specific myelin protein mRNA. Journal of Neuroscience Research. 47(6):603–8.
    • (1997) Journal of Neuroscience Research , vol.47 , Issue.6 , pp. 603-8
    • Escobar Cabrera, O.E.1    Zakin, M.M.2    Soto, E.F.3    Pasquini, J.M.4
  • 36
    • 0029065064 scopus 로고
    • Cellular Distribution of Iron, Transferrin and Ferritin in Hypotransferrinemic (Hp) Mouse Brain
    • 36. K.T. Dikinson R.J. Connor 1995 Cellular Distribution of Iron, Transferrin and Ferritin in Hypotransferrinemic (Hp) Mouse Brain Journal of Comparative Neurology 355 67 80 7636015 Dikinson K.T. and Connor R.J. 1995. Cellular Distribution of Iron, Transferrin and Ferritin in Hypotransferrinemic (Hp) Mouse Brain. Journal of Comparative Neurology, 355:67–80.
    • (1995) Journal of Comparative Neurology , vol.355 , pp. 67-80
    • Dikinson, K.T.1    Connor, R.J.2


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