A novel selective androgen receptor modulator, NEP28, is efficacious in muscle and brain without serious side effects on prostate

European Journal of Pharmacology

Volumn 720, Issue 1-3, 2013, Pages 107-114

  Akita, Kazumasa ^a   Harada, Koichiro ^a   Ichihara, Junji ^b   Takata, Naoko ^a   Takahashi, Yasuhiko ^a   Saito, Koichi ^a  

^a SUMITOMO CHEMICAL CO LTD   (Japan)

^b DAINIPPON SUMITOMO PHARMA CO LTD   (Japan)

Author keywords

Amyloid; Androgen; Neprilysin; SARM; Selective androgen receptor modulator

Indexed keywords

ANDROGEN; ANDROGEN RECEPTOR; ANDROSTANOLONE; MEMBRANE METALLOENDOPEPTIDASE; METHYLTESTOSTERONE; PLACEBO; SELECTIVE ANDROGEN RECEPTOR MODULATOR; SELECTIVE ANDROGEN RECEPTOR MODULATOR NEP28; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANDROGEN DEPLETION; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DEPLETION; DRUG ACTIVITY; DRUG EFFICACY; DRUG PROTEIN BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVITY; HUMAN; HUMAN CELL; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; ORCHIECTOMY; OSTEOPOROSIS; PRIORITY JOURNAL; PROSTATE DISEASE; RAT; SARCOPENIA; STRUCTURE ACTIVITY RELATION;

AMYLOID; ANDROGEN; NEPRILYSIN; SARM; SELECTIVE ANDROGEN RECEPTOR MODULATOR;

AMYLOID BETA-PEPTIDES; ANDROGENS; ANIMALS; BRAIN; CELL LINE, TUMOR; HELA CELLS; HUMANS; MALE; MUSCLE, SKELETAL; NEPRILYSIN; ORCHIECTOMY; ORGAN SIZE; PROSTATE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ANDROGEN; THIOPHENES;

EID: 84890120019     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2013.10.042     Document Type: Article

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