Experimental models to study drug distributions in tissue using MALDI mass spectrometry imaging

Journal of Proteome Research

Volumn 12, Issue 12, 2013, Pages 5626-5633

  Végvári, Ákos ^a,b   Fehniger, Thomas E ^b,c   Rezeli, Melinda ^a   Laurell, Thomas ^a   Döme, Balázs ^d,e   Jansson, Bo ^f   Welinder, Charlotte ^b   Marko Varga, György ^a,g  

^a LUND UNIVERSITY   (Sweden)

^b LUND UNIVERSITY   (Sweden)

^c TALLINN UNIVERSITY OF TECHNOLOGY   (Estonia)

^d MEDICAL UNIVERSITY OF VIENNA   (Austria)

^e NATIONAL KORANYI INSTITUTE OF PULMONOLOGY   (Hungary)

^f Bioinvent Int AB   (Sweden)

^g TOKYO MEDICAL UNIVERSITY   (Japan)

Author keywords

adenocarcinoma; erlotinib; gefitinib; lung cancer; MALDI mass spectrometry imaging; tiotropium

Indexed keywords

ERLOTINIB; GEFITINIB; TIOTROPIUM BROMIDE; CHOLINERGIC RECEPTOR BLOCKING AGENT; PROTEIN KINASE INHIBITOR; QUINAZOLINE DERIVATIVE; SCOPOLAMINE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG ABSORPTION; DRUG ADSORPTION; DRUG DIFFUSION; DRUG DISPOSITION; DRUG DISTRIBUTION; DRUG TISSUE LEVEL; DRUG TRANSPORT; EXPERIMENTAL MODEL; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MASS SPECTROMETER; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MOUSE; NONHUMAN; PRIORITY JOURNAL; TUMOR XENOGRAFT; ADENOCARCINOMA; ANIMAL; CHEMISTRY; EXPERIMENTAL NEOPLASM; LUNG NEOPLASMS; MASS SPECTROMETRY; METABOLISM; MICROTOMY; TISSUE CULTURE TECHNIQUE; TRANSPORT AT THE CELLULAR LEVEL; TUMOR MICROENVIRONMENT;

ADENOCARCINOMA; ANIMALS; BIOLOGICAL TRANSPORT; CHOLINERGIC ANTAGONISTS; HUMANS; LUNG NEOPLASMS; MICE; MICROTOMY; NEOPLASMS, EXPERIMENTAL; PROTEIN KINASE INHIBITORS; QUINAZOLINES; SCOPOLAMINE DERIVATIVES; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; TISSUE CULTURE TECHNIQUES; TUMOR MICROENVIRONMENT;

EID: 84890104949     PISSN: 15353893     EISSN: 15353907     Source Type: Journal    
DOI: 10.1021/pr400581b     Document Type: Article

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