XParallel, redundant circuit organization for homeostatic control of feeding behavior

Cell

Volumn 155, Issue 6, 2013, Pages

  Betley, J Nicholas ^a   Cao, Zhen Fang Huang ^a   Ritola, Kimberly D ^a   Sternson, Scott M ^a  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL SUBPOPULATION; CONTROLLED STUDY; DORSOMEDIAL HYPOTHALAMIC NUCLEUS; FEEDING BEHAVIOR; HIPPOCAMPUS; HOMEOSTASIS; INSULA; MOUSE; NERVE CIRCUIT; NERVE FIBER; NERVOUS SYSTEM PARAMETERS; NONHUMAN; PRIORITY JOURNAL; SUBICULUM; THALAMUS NUCLEUS; ANIMAL; BRAIN; METABOLISM; NERVE CELL; NERVE TRACT; PHYSIOLOGY;

AGOUTI RELATED PROTEIN; AGRP PROTEIN, MOUSE; GHRELIN;

AGOUTI-RELATED PROTEIN; ANIMALS; BRAIN; FEEDING BEHAVIOR; GHRELIN; HOMEOSTASIS; MICE; NEURAL PATHWAYS; NEURONS;

EID: 84890097302     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2013.11.002     Document Type: Article

References (50)

1. Y. Aponte, D. Atasoy, and S.M. Sternson AGRP neurons are sufficient to orchestrate feeding behavior rapidly and without training Nat. Neurosci. 14 2011 351 355
2. A.M. Aravanis, L.P. Wang, F. Zhang, L.A. Meltzer, M.Z. Mogri, M.B. Schneider, and K. Deisseroth An optical neural interface: in vivo control of rodent motor cortex with integrated fiberoptic and optogenetic technology J. Neural Eng. 4 2007 S143 S156
3. D. Atasoy, Y. Aponte, H.H. Su, and S.M. Sternson A FLEX switch targets Channelrhodopsin-2 to multiple cell types for imaging and long-range circuit mapping J. Neurosci. 28 2008 7025 7030
4. D. Atasoy, J.N. Betley, H.H. Su, and S.M. Sternson Deconstruction of a neural circuit for hunger Nature 488 2012 172 177
5. N. Balthasar, L.T. Dalgaard, C.E. Lee, J. Yu, H. Funahashi, T. Williams, M. Ferreira, V. Tang, R.A. McGovern, and C.D. Kenny Divergence of melanocortin pathways in the control of food intake and energy expenditure Cell 123 2005 493 505
6. B.F. Belgardt, T. Okamura, and J.C. Brüning Hormone and glucose signalling in POMC and AgRP neurons J. Physiol. 587 2009 5305 5314
7. B.M. Chronwall Anatomy and physiology of the neuroendocrine arcuate nucleus Peptides 6 Suppl 2 1985 1 11
8. M. Claret, M.A. Smith, R.L. Batterham, C. Selman, A.I. Choudhury, L.G. Fryer, M. Clements, H. Al-Qassab, H. Heffron, and A.W. Xu AMPK is essential for energy homeostasis regulation and glucose sensing by POMC and AgRP neurons J. Clin. Invest. 117 2007 2325 2336
9. J.M. Delgado, and B.K. Anand Increase of food intake induced by electrical stimulation of the lateral hypothalamus Am. J. Physiol. 172 1953 162 168
10. S. Diano, F. Naftolin, F. Goglia, V. Csernus, and T.L. Horvath Monosynaptic pathway between the arcuate nucleus expressing glial type II iodothyronine 5′-deiodinase mRNA and the median eminence-projective TRH cells of the rat paraventricular nucleus J. Neuroendocrinol. 10 1998 731 742
11. M.S. Fanselow, and H.W. Dong Are the dorsal and ventral hippocampus functionally distinct structures? Neuron 65 2010 7 19
12. J.D. Hahn, and L.W. Swanson Distinct patterns of neuronal inputs and outputs of the juxtaparaventricular and suprafornical regions of the lateral hypothalamic area in the male rat Brain Res. Brain Res. Rev. 64 2010 14 103
13. W.R. Hess The functional organization of the diencephalon 1957 Grune & Stratton New York
14. C.-C. Huang, K. Sugino, Y. Shima, C. Guo, S. Bai, B.D. Mensh, S.B. Nelson, and A.W. Hantman Convergence of pontine and proprioceptive streams onto multimodal cerebellar granule cells Elife 2 2013 e00400
15. J. Kelly, G.F. Alheid, A. Newberg, and S.P. Grossman GABA stimulation and blockade in the hypothalamus and midbrain: effects on feeding and locomotor activity Pharmacol. Biochem. Behav. 7 1977 537 541
16. A.L. Kirchgessner, and A. Sclafani PVN-hindbrain pathway involved in the hypothalamic hyperphagia-obesity syndrome Physiol. Behav. 42 1988 517 528
17. L.M. Kow, M.O. Montgomery, and D.W. Pfaff Effects of spinal cord transections on lordosis reflex in female rats Brain Res. 123 1977 75 88
18. M.J. Krashes, S. Koda, C. Ye, S.C. Rogan, A.C. Adams, D.S. Cusher, E. Maratos-Flier, B.L. Roth, and B.B. Lowell Rapid, reversible activation of AgRP neurons drives feeding behavior in mice J. Clin. Invest. 121 2011 1424 1428
19. M.R. Kruk, A.M. Van der Poel, W. Meelis, J. Hermans, P.G. Mostert, J. Mos, and A.H. Lohman Discriminant analysis of the localization of aggression-inducing electrode placements in the hypothalamus of male rats Brain Res. 260 1983 61 79
20. H.G. Kuypers, C.E. Catsman-Berrevoets, and R.E. Padt Retrograde anoxal transport of fluorescent substances in the rat's forebrain Neurosci. Lett. 6 1977 127 133
21. S.Q. Lima, T. Hromádka, P. Znamenskiy, and A.M. Zador PINP: a new method of tagging neuronal populations for identification during in vivo electrophysiological recording PLoS ONE 4 2009 e6099
22. J.Y. Lin, M.Z. Lin, P. Steinbach, and R.Y. Tsien Characterization of engineered channelrhodopsin variants with improved properties and kinetics Biophys. J. 96 2009 1803 1814
23. S. Luquet, F.A. Perez, T.S. Hnasko, and R.D. Palmiter NPY/AgRP neurons are essential for feeding in adult mice but can be ablated in neonates Science 310 2005 683 685
24. V. Napadow, J.D. Sheehan, J. Kim, L.T. Lacount, K. Park, T.J. Kaptchuk, B.R. Rosen, and B. Kuo The brain circuitry underlying the temporal evolution of nausea in humans Cereb. Cortex 23 2013 806 813
25. S.L. Padilla, J.S. Carmody, and L.M. Zeltser Pomc-expressing progenitors give rise to antagonistic neuronal populations in hypothalamic feeding circuits Nat. Med. 16 2010 403 405
26. P.Y. Risold, R.H. Thompson, and L.W. Swanson The structural organization of connections between hypothalamus and cerebral cortex Brain Res. Brain Res. Rev. 24 1997 197 254
27. T.A. Roeling, J.G. Veening, M.R. Kruk, J.P. Peters, M.E. Vermelis, and R. Nieuwenhuys Efferent connections of the hypothalamic "aggression area" in the rat Neuroscience 59 1994 1001 1024
28. J.W. Shin, J.C. Geerling, and A.D. Loewy Inputs to the ventrolateral bed nucleus of the stria terminalis J. Comp. Neurol. 511 2008 628 657
29. S.M. Sternson Hypothalamic survival circuits: blueprints for purposive behaviors Neuron 77 2013 810 824
30. P. Stockinger, D. Kvitsiani, S. Rotkopf, L. Tirián, and B.J. Dickson Neural circuitry that governs Drosophila male courtship behavior Cell 121 2005 795 807
31. T.R. Stratford, and D. Wirtshafter Injections of muscimol into the paraventricular thalamic nucleus, but not mediodorsal thalamic nuclei, induce feeding in rats Brain Res. 1490 2013 128 133
32. L.W. Swanson Cerebral hemisphere regulation of motivated behavior Brain Res. 886 2000 113 164
33. N. Tinbergen The Study of Instinct 1989 Oxford University Press New York
34. E. van de Wall, R. Leshan, A.W. Xu, N. Balthasar, R. Coppari, S.M. Liu, Y.H. Jo, R.G. MacKenzie, D.B. Allison, and N.J. Dun Collective and individual functions of leptin receptor modulated neurons controlling metabolism and ingestion Endocrinology 149 2008 1773 1785
35. M. van den Top, K. Lee, A.D. Whyment, A.M. Blanks, and D. Spanswick Orexigen-sensitive NPY/AgRP pacemaker neurons in the hypothalamic arcuate nucleus Nat. Neurosci. 7 2004 493 494
36. N.R. Wall, I.R. Wickersham, A. Cetin, M. De La Parra, and E.M. Callaway Monosynaptic circuit tracing in vivo through Cre-dependent targeting and complementation of modified rabies virus Proc. Natl. Acad. Sci. USA 107 2010 21848 21853
37. I.R. Wickersham, D.C. Lyon, R.J. Barnard, T. Mori, S. Finke, K.K. Conzelmann, J.A. Young, and E.M. Callaway Monosynaptic restriction of transsynaptic tracing from single, genetically targeted neurons Neuron 53 2007 639 647
38. G. Wittmann, T. Füzesi, P.S. Singru, Z. Liposits, R.M. Lechan, and C. Fekete Efferent projections of thyrotropin-releasing hormone-synthesizing neurons residing in the anterior parvocellular subdivision of the hypothalamic paraventricular nucleus J. Comp. Neurol. 515 2009 313 330
39. Q. Wu, M.S. Clark, and R.D. Palmiter Deciphering a neuronal circuit that mediates appetite Nature 483 2012 594 597
40. Q. Wu, B.B. Whiddon, and R.D. Palmiter Ablation of neurons expressing agouti-related protein, but not melanin concentrating hormone, in leptin-deficient mice restores metabolic functions and fertility Proc. Natl. Acad. Sci. USA 109 2012 3155 3160
41. Y. Yang, D. Atasoy, H.H. Su, and S.M. Sternson Hunger states switch a flip-flop memory circuit via a synaptic AMPK-dependent positive feedback loop Cell 146 2011 992 1003
42. M. Abercrombie Estimation of nuclear population from microtome sections Anat. Rec. 94 1946 239 247
43. J.S. Dasen, B.C. Tice, S. Brenner-Morton, and T.M. Jessell A Hox regulatory network establishes motor neuron pool identity and target-muscle connectivity Cell 123 2005 477 491
44. R.L. Leshan, M. Björnholm, H. Münzberg, and M.G. Myers Jr. Leptin receptor signaling and action in the central nervous system Obesity (Silver Spring) 14 Suppl 5 2006 208S 212S
45. L. Madisen, T.A. Zwingman, S.M. Sunkin, S.W. Oh, H.A. Zariwala, H. Gu, L.L. Ng, R.D. Palmiter, M.J. Hawrylycz, and A.R. Jones A robust and high-throughput Cre reporting and characterization system for the whole mouse brain Nat. Neurosci. 13 2010 133 140
46. L. Madisen, T. Mao, H. Koch, J.M. Zhuo, A. Berenyi, S. Fujisawa, Y.W. Hsu, A.J. Garcia 3rd, X. Gu, and S. Zanella A toolbox of Cre-dependent optogenetic transgenic mice for light-induced activation and silencing Nat. Neurosci. 15 2012 793 802
47. H. Peng, Z. Ruan, D. Atasoy, and S. Sternson Automatic reconstruction of 3D neuron structures using a graph-augmented deformable model Bioinformatics 26 2010 i38 i46
48. J.Z. Stoller, K.R. Degenhardt, L. Huang, D.D. Zhou, M.M. Lu, and J.A. Epstein Cre reporter mouse expressing a nuclear localized fusion of GFP and beta-galactosidase reveals new derivatives of Pax3-expressing precursors Genesis 46 2008 200 204
49. Q. Tong, C.P. Ye, J.E. Jones, J.K. Elmquist, and B.B. Lowell Synaptic release of GABA by AgRP neurons is required for normal regulation of energy balance Nat. Neurosci. 11 2008 998 1000
50. I.R. Wickersham, H.A. Sullivan, and H.S. Seung Production of glycoprotein-deleted rabies viruses for monosynaptic tracing and high-level gene expression in neurons Nat. Protoc. 5 2010 595 606