Direct evidence of iNOS-mediated in vivo free radical production and protein oxidation in acetone-induced ketosis

American Journal of Physiology - Endocrinology and Metabolism

Volumn 295, Issue 2, 2008, Pages

  Stadler, Krisztian ^a   Bonini, Marcelo G ^a   Dallas, Shannon ^a   Duma, Danielle ^a   Mason, Ronald P ^a   Kadiiska, Maria B ^a  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

Acetone; Electron paramagnetic resonance; Free radicals; Inducible nitric oxide synthase

Indexed keywords

ACETONE; FREE RADICAL; INDUCIBLE NITRIC OXIDE SYNTHASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; (PYRIDYL 4 N OXIDE) N TERT BUTYLNITRONE; (PYRIDYL-4-N-OXIDE)-N-TERT-BUTYLNITRONE; PROTEIN; PYRIDINE DERIVATIVE; RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; ELECTRON SPIN RESONANCE; ENZYME ANALYSIS; IMMUNOHISTOCHEMISTRY; KETOACIDOSIS; KNOCKOUT MOUSE; LIPID PEROXIDATION; LONG TERM EXPOSURE; MALE; MOUSE; NONHUMAN; OXIDATION; PRIORITY JOURNAL; PROTEIN METABOLISM; SPIN TRAPPING; ANIMAL; C57BL MOUSE; CHEMICALLY INDUCED DISORDER; CHEMISTRY; DRUG EFFECT; ENZYMOLOGY; GENETICS; LIPID METABOLISM; LIVER; METABOLISM; MOUSE MUTANT; OXIDATION REDUCTION REACTION; PATHOLOGY; PROTEIN CARBONYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ACETONE; ANIMALS; ELECTRON SPIN RESONANCE SPECTROSCOPY; FREE RADICALS; IMMUNOHISTOCHEMISTRY; KETOSIS; LIPID METABOLISM; LIVER; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROSCOPY, CONFOCAL; NADPH OXIDASE; NITRIC OXIDE SYNTHASE TYPE II; OXIDATION-REDUCTION; PROTEIN CARBONYLATION; PROTEINS; PYRIDINES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA;

EID: 52649154098     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00015.2008     Document Type: Article

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