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Volumn 7, Issue 11-12, 2013, Pages 767-778

MALDI-TOF MS: An upcoming tool for rapid detection of antibiotic resistance in microorganisms

Author keywords

Clinical microbiology; Diagnostic; MALDI TOF MS; Resistance detection

Indexed keywords

AMINOGLYCOSIDE; ANTIBIOTIC AGENT; BETA LACTAM ANTIBIOTIC; BETA LACTAMASE; FLUCONAZOLE;

EID: 84890042943     PISSN: 18628346     EISSN: 18628354     Source Type: Journal    
DOI: 10.1002/prca.201300042     Document Type: Article
Times cited : (108)

References (80)
  • 1
    • 0029777367 scopus 로고    scopus 로고
    • Rapid identification of intact whole bacteria based on spectral patterns using matrix-assisted laser desorption/ionization with time-of-flight mass spectrometry
    • Holland, R. D., Wilkes, J. G., Rafii, F., Sutherland, J. B. et al., Rapid identification of intact whole bacteria based on spectral patterns using matrix-assisted laser desorption/ionization with time-of-flight mass spectrometry. Rapid Commun. Mass Spectrom. RCM 1996, 10, 1227-1232.
    • (1996) Rapid Commun. Mass Spectrom. RCM , vol.10 , pp. 1227-1232
    • Holland, R.D.1    Wilkes, J.G.2    Rafii, F.3    Sutherland, J.B.4
  • 2
    • 0029998033 scopus 로고    scopus 로고
    • The rapid identification of intact microorganisms using mass spectrometry
    • Claydon, M. A., Davey, S. N., Edwards-Jones, V., Gordon, D. B., The rapid identification of intact microorganisms using mass spectrometry. Nat. Biotechnol. 1996, 14, 1584-1586.
    • (1996) Nat. Biotechnol. , vol.14 , pp. 1584-1586
    • Claydon, M.A.1    Davey, S.N.2    Edwards-Jones, V.3    Gordon, D.B.4
  • 3
    • 0030467690 scopus 로고    scopus 로고
    • Rapid identification of bacteria by direct matrix-assisted laser desorption/ionization mass spectrometric analysis of whole cells
    • Krishnamurthy, T., Ross, P. L., Rapid identification of bacteria by direct matrix-assisted laser desorption/ionization mass spectrometric analysis of whole cells. Rapid Commun. Mass Spectrom. RCM 1996, 10, 1992-1996.
    • (1996) Rapid Commun. Mass Spectrom. RCM , vol.10 , pp. 1992-1996
    • Krishnamurthy, T.1    Ross, P.L.2
  • 4
    • 67651108596 scopus 로고    scopus 로고
    • Ongoing revolution in bacteriology: routine identification of bacteria by matrix-assisted laser desorption ionization time-of-flight mass spectrometry
    • Seng, P., Drancourt, M., Gouriet, F., La Scola, B. et al., Ongoing revolution in bacteriology: routine identification of bacteria by matrix-assisted laser desorption ionization time-of-flight mass spectrometry. Clin. Infect. Dis. Off. Publ. Infect. Dis. Soc. Am. 2009, 49, 543-551.
    • (2009) Clin. Infect. Dis. Off. Publ. Infect. Dis. Soc. Am. , vol.49 , pp. 543-551
    • Seng, P.1    Drancourt, M.2    Gouriet, F.3    La Scola, B.4
  • 5
    • 79953869376 scopus 로고    scopus 로고
    • Performance and cost analysis of matrix-assisted laser desorption ionization-time of flight mass spectrometry for routine identification of yeast
    • Dhiman, N., Hall, L., Wohlfiel, S. L., Buckwalter, S. P., Wengenack, N. L., Performance and cost analysis of matrix-assisted laser desorption ionization-time of flight mass spectrometry for routine identification of yeast. J. Clin. Microbiol. 2011, 49, 1614-1616.
    • (2011) J. Clin. Microbiol. , vol.49 , pp. 1614-1616
    • Dhiman, N.1    Hall, L.2    Wohlfiel, S.L.3    Buckwalter, S.P.4    Wengenack, N.L.5
  • 6
    • 84866460224 scopus 로고    scopus 로고
    • Prospective evaluation of a matrix-assisted laser desorption ionization-time of flight mass spectrometry system in a hospital clinical microbiology laboratory for identification of bacteria and yeasts: a bench-by-bench study for assessing the impact on time to identification and cost-effectiveness
    • Tan, K. E., Ellis, B. C., Lee, R., Stamper, P. D. et al., Prospective evaluation of a matrix-assisted laser desorption ionization-time of flight mass spectrometry system in a hospital clinical microbiology laboratory for identification of bacteria and yeasts: a bench-by-bench study for assessing the impact on time to identification and cost-effectiveness. J. Clin. Microbiol. 2012, 50, 3301-3308.
    • (2012) J. Clin. Microbiol. , vol.50 , pp. 3301-3308
    • Tan, K.E.1    Ellis, B.C.2    Lee, R.3    Stamper, P.D.4
  • 7
    • 84866450171 scopus 로고    scopus 로고
    • Identification of blood culture isolates directly from positive blood cultures by use of matrix-assisted laser desorption ionization-time of flight mass spectrometry and a commercial extraction system: analysis of performance, cost, and turnaround time
    • Lagacé-Wiens, P. R. S., Adam, H. J., Karlowsky, J. A., Nichol, K. A. et al., Identification of blood culture isolates directly from positive blood cultures by use of matrix-assisted laser desorption ionization-time of flight mass spectrometry and a commercial extraction system: analysis of performance, cost, and turnaround time. J. Clin. Microbiol. 2012, 50, 3324-3328.
    • (2012) J. Clin. Microbiol. , vol.50 , pp. 3324-3328
    • Lagacé-Wiens, P.R.S.1    Adam, H.J.2    Karlowsky, J.A.3    Nichol, K.A.4
  • 8
    • 45149125131 scopus 로고    scopus 로고
    • Evaluation of matrix-assisted laser desorption ionization-time-of-flight mass spectrometry in comparison to 16S rRNA gene sequencing for species identification of nonfermenting bacteria
    • Mellmann, A., Cloud, J., Maier, T., Keckevoet, U. et al., Evaluation of matrix-assisted laser desorption ionization-time-of-flight mass spectrometry in comparison to 16S rRNA gene sequencing for species identification of nonfermenting bacteria. J. Clin. Microbiol. 2008, 46, 1946-1954.
    • (2008) J. Clin. Microbiol. , vol.46 , pp. 1946-1954
    • Mellmann, A.1    Cloud, J.2    Maier, T.3    Keckevoet, U.4
  • 10
    • 69249131780 scopus 로고    scopus 로고
    • Species identification of clinical isolates of Bacteroides by matrix-assisted laser-desorption/ionization time-of-flight mass spectrometry
    • Nagy, E., Maier, T., Urban, E., Terhes, G. et al., Species identification of clinical isolates of Bacteroides by matrix-assisted laser-desorption/ionization time-of-flight mass spectrometry. Clin. Microbiol. Infect. Off. Publ. Eur. Soc. Clin. Microbiol. Infect. Dis. 2009, 15, 796-802.
    • (2009) Clin. Microbiol. Infect. Off. Publ. Eur. Soc. Clin. Microbiol. Infect. Dis. , vol.15 , pp. 796-802
    • Nagy, E.1    Maier, T.2    Urban, E.3    Terhes, G.4
  • 11
    • 80053082459 scopus 로고    scopus 로고
    • Comparison of two matrix-assisted laser desorption ionisation-time of flight mass spectrometry methods for the identification of clinically relevant anaerobic bacteria
    • Veloo, A. C. M., Knoester, M., Degener, J. E., Kuijper, E. J., Comparison of two matrix-assisted laser desorption ionisation-time of flight mass spectrometry methods for the identification of clinically relevant anaerobic bacteria. Clin. Microbiol. Infect. Off. Publ. Eur. Soc. Clin. Microbiol. Infect. Dis. 2011, 17, 1501-1506.
    • (2011) Clin. Microbiol. Infect. Off. Publ. Eur. Soc. Clin. Microbiol. Infect. Dis. , vol.17 , pp. 1501-1506
    • Veloo, A.C.M.1    Knoester, M.2    Degener, J.E.3    Kuijper, E.J.4
  • 12
    • 84866354781 scopus 로고    scopus 로고
    • Identification of clinical isolates of anaerobic bacteria using matrix-assisted laser desorption ionization-time of flight mass spectrometry
    • Fedorko, D. P., Drake, S. K., Stock, F., Murray, P. R., Identification of clinical isolates of anaerobic bacteria using matrix-assisted laser desorption ionization-time of flight mass spectrometry. Eur. J. Clin. Microbiol. Infect. Dis. Off. Publ. Eur. Soc. Clin. Microbiol. 2012, 31, 2257-2262.
    • (2012) Eur. J. Clin. Microbiol. Infect. Dis. Off. Publ. Eur. Soc. Clin. Microbiol. , vol.31 , pp. 2257-2262
    • Fedorko, D.P.1    Drake, S.K.2    Stock, F.3    Murray, P.R.4
  • 13
    • 84858607944 scopus 로고    scopus 로고
    • Routine identification of clinical isolates of anaerobic bacteria: matrix-assisted laser desorption ionization-time of flight mass spectrometry performs better than conventional identification methods
    • Knoester, M., van Veen, S. Q., Claas, E. C. J., Kuijper, E. J., Routine identification of clinical isolates of anaerobic bacteria: matrix-assisted laser desorption ionization-time of flight mass spectrometry performs better than conventional identification methods. J. Clin. Microbiol. 2012, 50, 1504.
    • (2012) J. Clin. Microbiol. , vol.50 , pp. 1504
    • Knoester, M.1    van Veen, S.Q.2    Claas, E.C.J.3    Kuijper, E.J.4
  • 14
    • 84866414204 scopus 로고    scopus 로고
    • The value of MALDI-TOF MS for the identification of clinically relevant anaerobic bacteria in routine laboratories
    • Nagy, E., Becker, S., Kostrzewa, M., Barta, N., Urbán, E., The value of MALDI-TOF MS for the identification of clinically relevant anaerobic bacteria in routine laboratories. J. Med. Microbiol. 2012, 61, 1393-1400.
    • (2012) J. Med. Microbiol. , vol.61 , pp. 1393-1400
    • Nagy, E.1    Becker, S.2    Kostrzewa, M.3    Barta, N.4    Urbán, E.5
  • 15
    • 69949108671 scopus 로고    scopus 로고
    • Matrix-assisted laser desorption ionization-time of flight mass spectrometry for fast and reliable identification of clinical yeast isolates
    • Marklein, G., Josten, M., Klanke, U., Müller, E. et al., Matrix-assisted laser desorption ionization-time of flight mass spectrometry for fast and reliable identification of clinical yeast isolates. J. Clin. Microbiol. 2009, 47, 2912-2917.
    • (2009) J. Clin. Microbiol. , vol.47 , pp. 2912-2917
    • Marklein, G.1    Josten, M.2    Klanke, U.3    Müller, E.4
  • 16
    • 77957809580 scopus 로고    scopus 로고
    • Evaluation of matrix-assisted laser desorption ionization-time of flight mass spectrometry for identification of clinically important yeast species
    • Stevenson, L. G., Drake, S. K., Shea, Y. R., Zelazny, A. M., Murray, P. R., Evaluation of matrix-assisted laser desorption ionization-time of flight mass spectrometry for identification of clinically important yeast species. J. Clin. Microbiol. 2010, 48, 3482-3486.
    • (2010) J. Clin. Microbiol. , vol.48 , pp. 3482-3486
    • Stevenson, L.G.1    Drake, S.K.2    Shea, Y.R.3    Zelazny, A.M.4    Murray, P.R.5
  • 17
    • 80051876952 scopus 로고    scopus 로고
    • Improved clinical laboratory identification of human pathogenic yeasts by matrix-assisted laser desorption ionization time-of-flight mass spectrometry
    • Bader, O., Weig, M., Taverne-Ghadwal, L., Lugert, R. et al., Improved clinical laboratory identification of human pathogenic yeasts by matrix-assisted laser desorption ionization time-of-flight mass spectrometry. Clin. Microbiol. Infect. Off. Publ. Eur. Soc. Clin. Microbiol. Infect. Dis. 2011, 17, 1359-1365.
    • (2011) Clin. Microbiol. Infect. Off. Publ. Eur. Soc. Clin. Microbiol. Infect. Dis. , vol.17 , pp. 1359-1365
    • Bader, O.1    Weig, M.2    Taverne-Ghadwal, L.3    Lugert, R.4
  • 18
    • 84876705043 scopus 로고    scopus 로고
    • Advances in identification of clinical yeast isolates by use of matrix-assisted laser desorption ionization-time of flight mass spectrometry
    • Buchan, B. W., Ledeboer, N. A., Advances in identification of clinical yeast isolates by use of matrix-assisted laser desorption ionization-time of flight mass spectrometry. J. Clin. Microbiol. 2013, 51, 1359-1366.
    • (2013) J. Clin. Microbiol. , vol.51 , pp. 1359-1366
    • Buchan, B.W.1    Ledeboer, N.A.2
  • 19
    • 69049098121 scopus 로고    scopus 로고
    • Rapid and cost-effective identification of Bartonella species using mass spectrometry
    • Fournier, P.-E., Couderc, C., Buffet, S., Flaudrops, C., Raoult, D., Rapid and cost-effective identification of Bartonella species using mass spectrometry. J. Med. Microbiol. 2009, 58, 1154-1159.
    • (2009) J. Med. Microbiol. , vol.58 , pp. 1154-1159
    • Fournier, P.-E.1    Couderc, C.2    Buffet, S.3    Flaudrops, C.4    Raoult, D.5
  • 20
    • 84869780783 scopus 로고    scopus 로고
    • Use of MALDI-TOF mass spectrometry for identification of bacteria that are difficult to culture
    • Biswas, S., Rolain, J.-M., Use of MALDI-TOF mass spectrometry for identification of bacteria that are difficult to culture. J. Microbiol. Methods 2013, 92, 14-24.
    • (2013) J. Microbiol. Methods , vol.92 , pp. 14-24
    • Biswas, S.1    Rolain, J.-M.2
  • 21
    • 77950489985 scopus 로고    scopus 로고
    • Identification of Francisella tularensis by whole-cell matrix-assisted laser desorption ionization-time of flight mass spectrometry: fast, reliable, robust, and cost-effective differentiation on species and subspecies levels
    • Seibold, E., Maier, T., Kostrzewa, M., Zeman, E., Splettstoesser, W., Identification of Francisella tularensis by whole-cell matrix-assisted laser desorption ionization-time of flight mass spectrometry: fast, reliable, robust, and cost-effective differentiation on species and subspecies levels. J. Clin. Microbiol. 2010, 48, 1061-1069.
    • (2010) J. Clin. Microbiol. , vol.48 , pp. 1061-1069
    • Seibold, E.1    Maier, T.2    Kostrzewa, M.3    Zeman, E.4    Splettstoesser, W.5
  • 22
    • 84155173339 scopus 로고    scopus 로고
    • Reliable identification at the species level of Brucella isolates with MALDI-TOF-MS
    • Lista, F., Reubsaet, F. A. G., De Santis, R., Parchen, R. R. et al., Reliable identification at the species level of Brucella isolates with MALDI-TOF-MS. BMC Microbiol. 2011, 11, 267.
    • (2011) BMC Microbiol. , vol.11 , pp. 267
    • Lista, F.1    Reubsaet, F.A.G.2    De Santis, R.3    Parchen, R.R.4
  • 23
    • 76649102389 scopus 로고    scopus 로고
    • Rapid identification of Legionella species by mass spectrometry
    • Moliner, C., Ginevra, C., Jarraud, S., Flaudrops, C. et al., Rapid identification of Legionella species by mass spectrometry. J. Med. Microbiol. 2010, 59, 273-284.
    • (2010) J. Med. Microbiol. , vol.59 , pp. 273-284
    • Moliner, C.1    Ginevra, C.2    Jarraud, S.3    Flaudrops, C.4
  • 24
    • 79955528822 scopus 로고    scopus 로고
    • Identification of mycobacteria in solid-culture media by matrix-assisted laser desorption ionization-time of flight mass spectrometry
    • Saleeb, P. G., Drake, S. K., Murray, P. R., Zelazny, A. M., Identification of mycobacteria in solid-culture media by matrix-assisted laser desorption ionization-time of flight mass spectrometry. J. Clin. Microbiol. 2011, 49, 1790-1794.
    • (2011) J. Clin. Microbiol. , vol.49 , pp. 1790-1794
    • Saleeb, P.G.1    Drake, S.K.2    Murray, P.R.3    Zelazny, A.M.4
  • 25
    • 80052745935 scopus 로고    scopus 로고
    • Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry identification of mycobacteria in routine clinical practice
    • El Khéchine, A., Couderc, C., Flaudrops, C., Raoult, D., Drancourt, M., Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry identification of mycobacteria in routine clinical practice. PloS One 2011, 6, e24720.
    • (2011) PloS One , vol.6
    • El Khéchine, A.1    Couderc, C.2    Flaudrops, C.3    Raoult, D.4    Drancourt, M.5
  • 26
    • 83455212028 scopus 로고    scopus 로고
    • Mould routine identification in the clinical laboratory by matrix-assisted laser desorption ionization time-of-flight mass spectrometry
    • Cassagne, C., Ranque, S., Normand, A.-C., Fourquet, P. et al., Mould routine identification in the clinical laboratory by matrix-assisted laser desorption ionization time-of-flight mass spectrometry. PloS One 2011, 6, e28425.
    • (2011) PloS One , vol.6
    • Cassagne, C.1    Ranque, S.2    Normand, A.-C.3    Fourquet, P.4
  • 27
    • 84874059447 scopus 로고    scopus 로고
    • Development of a clinically comprehensive database and a simple procedure for identification of molds from solid media by matrix-assisted laser desorption ionization-time of flight mass spectrometry
    • Lau, A. F., Drake, S. K., Calhoun, L. B., Henderson, C. M., Zelazny, A. M., Development of a clinically comprehensive database and a simple procedure for identification of molds from solid media by matrix-assisted laser desorption ionization-time of flight mass spectrometry. J. Clin. Microbiol. 2013, 51, 828-834.
    • (2013) J. Clin. Microbiol. , vol.51 , pp. 828-834
    • Lau, A.F.1    Drake, S.K.2    Calhoun, L.B.3    Henderson, C.M.4    Zelazny, A.M.5
  • 28
    • 70350113480 scopus 로고    scopus 로고
    • Identification of harmless and pathogenic algae of the genus Prototheca by MALDI-MS
    • Von Bergen, M., Eidner, A., Schmidt, F., Murugaiyan, J. et al., Identification of harmless and pathogenic algae of the genus Prototheca by MALDI-MS. Proteomics Clin. Appl. 2009, 3, 774-784.
    • (2009) Proteomics Clin. Appl. , vol.3 , pp. 774-784
    • Von Bergen, M.1    Eidner, A.2    Schmidt, F.3    Murugaiyan, J.4
  • 29
    • 84858390004 scopus 로고    scopus 로고
    • Establishment of a matrix-assisted laser desorption ionization time-of-flight mass spectrometry database for rapid identification of infectious achlorophyllous green micro-algae of the genus Prototheca
    • Murugaiyan, J., Ahrholdt, J., Kowbel, V., Roesler, U., Establishment of a matrix-assisted laser desorption ionization time-of-flight mass spectrometry database for rapid identification of infectious achlorophyllous green micro-algae of the genus Prototheca. Clin. Microbiol. Infect. Off. Publ. Eur. Soc. Clin. Microbiol. Infect. Dis. 2012, 18, 461-467.
    • (2012) Clin. Microbiol. Infect. Off. Publ. Eur. Soc. Clin. Microbiol. Infect. Dis. , vol.18 , pp. 461-467
    • Murugaiyan, J.1    Ahrholdt, J.2    Kowbel, V.3    Roesler, U.4
  • 30
    • 70449646609 scopus 로고    scopus 로고
    • High interlaboratory reproducibility of matrix-assisted laser desorption ionization-time of flight mass spectrometry-based species identification of nonfermenting bacteria
    • Mellmann, A., Bimet, F., Bizet, C., Borovskaya, A. D. et al., High interlaboratory reproducibility of matrix-assisted laser desorption ionization-time of flight mass spectrometry-based species identification of nonfermenting bacteria. J. Clin. Microbiol. 2009, 47, 3732-3734.
    • (2009) J. Clin. Microbiol. , vol.47 , pp. 3732-3734
    • Mellmann, A.1    Bimet, F.2    Bizet, C.3    Borovskaya, A.D.4
  • 31
    • 77952898786 scopus 로고    scopus 로고
    • Direct identification of urinary tract pathogens from urine samples by matrix-assisted laser desorption ionization-time of flight mass spectrometry
    • Ferreira, L., Sánchez-Juanes, F., González-Avila, M., Cembrero-Fuciños, D. et al., Direct identification of urinary tract pathogens from urine samples by matrix-assisted laser desorption ionization-time of flight mass spectrometry. J. Clin. Microbiol. 2010, 48, 2110-2115.
    • (2010) J. Clin. Microbiol. , vol.48 , pp. 2110-2115
    • Ferreira, L.1    Sánchez-Juanes, F.2    González-Avila, M.3    Cembrero-Fuciños, D.4
  • 32
    • 84857067535 scopus 로고    scopus 로고
    • Direct identification of bacteria in urine samples by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry and relevance of defensins as interfering factors
    • Köhling, H. L., Bittner, A., Müller, K.-D., Buer, J. et al., Direct identification of bacteria in urine samples by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry and relevance of defensins as interfering factors. J. Med. Microbiol. 2012, 61, 339-344.
    • (2012) J. Med. Microbiol. , vol.61 , pp. 339-344
    • Köhling, H.L.1    Bittner, A.2    Müller, K.-D.3    Buer, J.4
  • 33
    • 84873965016 scopus 로고    scopus 로고
    • Direct identification of bacteria causing urinary tract infections by combining matrix-assisted laser desorption ionization-time of flight mass spectrometry with UF-1000i urine flow cytometry
    • Wang, X.-H., Zhang, G., Fan, Y.-Y., Yang, X. et al., Direct identification of bacteria causing urinary tract infections by combining matrix-assisted laser desorption ionization-time of flight mass spectrometry with UF-1000i urine flow cytometry. J. Microbiol. Methods 2013, 92, 231-235.
    • (2013) J. Microbiol. Methods , vol.92 , pp. 231-235
    • Wang, X.-H.1    Zhang, G.2    Fan, Y.-Y.3    Yang, X.4
  • 34
    • 71049140093 scopus 로고    scopus 로고
    • Direct identification of bacteria in positive blood culture bottles by matrix-assisted laser desorption ionisation time-of-flight mass spectrometry
    • La Scola, B., Raoult, D., Direct identification of bacteria in positive blood culture bottles by matrix-assisted laser desorption ionisation time-of-flight mass spectrometry. PloS One 2009, 4, e8041.
    • (2009) PloS One , vol.4
    • La Scola, B.1    Raoult, D.2
  • 35
    • 75649119276 scopus 로고    scopus 로고
    • Rapid identification of bacteria in positive blood culture broths by matrix-assisted laser desorption ionization-time of flight mass spectrometry
    • Stevenson, L. G., Drake, S. K., Murray, P. R., Rapid identification of bacteria in positive blood culture broths by matrix-assisted laser desorption ionization-time of flight mass spectrometry. J. Clin. Microbiol. 2010, 48, 444-447.
    • (2010) J. Clin. Microbiol. , vol.48 , pp. 444-447
    • Stevenson, L.G.1    Drake, S.K.2    Murray, P.R.3
  • 36
    • 82955198435 scopus 로고    scopus 로고
    • Novel, improved sample preparation for rapid, direct identification from positive blood cultures using matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry
    • Schubert, S., Weinert, K., Wagner, C., Gunzl, B. et al., Novel, improved sample preparation for rapid, direct identification from positive blood cultures using matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry. J. Mol. Diagn. 2011, 13, 701-706.
    • (2011) J. Mol. Diagn. , vol.13 , pp. 701-706
    • Schubert, S.1    Weinert, K.2    Wagner, C.3    Gunzl, B.4
  • 38
    • 0034092552 scopus 로고    scopus 로고
    • Rapid discrimination between methicillin-sensitive and methicillin-resistant Staphylococcus aureus by intact cell mass spectrometry
    • Edwards-Jones, V., Claydon, M. A., Evason, D. J., Walker, J. et al., Rapid discrimination between methicillin-sensitive and methicillin-resistant Staphylococcus aureus by intact cell mass spectrometry. J. Med. Microbiol. 2000, 49, 295-300.
    • (2000) J. Med. Microbiol. , vol.49 , pp. 295-300
    • Edwards-Jones, V.1    Claydon, M.A.2    Evason, D.J.3    Walker, J.4
  • 39
    • 0036149317 scopus 로고    scopus 로고
    • Intact cell mass spectrometry (ICMS) used to type methicillin-resistant Staphylococcus aureus: media effects and inter-laboratory reproducibility
    • Walker, J., Fox, A. J., Edwards-Jones, V., Gordon, D. B., Intact cell mass spectrometry (ICMS) used to type methicillin-resistant Staphylococcus aureus: media effects and inter-laboratory reproducibility. J. Microbiol. Methods 2002, 48, 117-126.
    • (2002) J. Microbiol. Methods , vol.48 , pp. 117-126
    • Walker, J.1    Fox, A.J.2    Edwards-Jones, V.3    Gordon, D.B.4
  • 40
    • 0036828654 scopus 로고    scopus 로고
    • Identification of Staphylococcus aureus and determination of its methicillin resistance by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry
    • Du, Z., Yang, R., Guo, Z., Song, Y., Wang, J., Identification of Staphylococcus aureus and determination of its methicillin resistance by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Anal. Chem. 2002, 74, 5487-5491.
    • (2002) Anal. Chem. , vol.74 , pp. 5487-5491
    • Du, Z.1    Yang, R.2    Guo, Z.3    Song, Y.4    Wang, J.5
  • 41
    • 0035987512 scopus 로고    scopus 로고
    • Identification and discrimination of Staphylococcus aureus strains using matrix-assisted laser desorption/ionization-time of flight mass spectrometry
    • Bernardo, K., Pakulat, N., Macht, M., Krut, O. et al., Identification and discrimination of Staphylococcus aureus strains using matrix-assisted laser desorption/ionization-time of flight mass spectrometry. Proteomics 2002, 2, 747-753.
    • (2002) Proteomics , vol.2 , pp. 747-753
    • Bernardo, K.1    Pakulat, N.2    Macht, M.3    Krut, O.4
  • 42
    • 23744468919 scopus 로고    scopus 로고
    • Optimisation of intact cell MALDI method for fingerprinting of methicillin-resistant Staphylococcus aureus
    • Jackson, K. A., Edwards-Jones, V., Sutton, C. W., Fox, A. J., Optimisation of intact cell MALDI method for fingerprinting of methicillin-resistant Staphylococcus aureus. J. Microbiol. Methods 2005, 62, 273-284.
    • (2005) J. Microbiol. Methods , vol.62 , pp. 273-284
    • Jackson, K.A.1    Edwards-Jones, V.2    Sutton, C.W.3    Fox, A.J.4
  • 43
    • 33645080916 scopus 로고    scopus 로고
    • The discriminatory power of MALDI-TOF mass spectrometry to differentiate between isogenic teicoplanin-susceptible and teicoplanin-resistant strains of methicillin-resistant Staphylococcus aureus
    • Majcherczyk, P. A., McKenna, T., Moreillon, P., Vaudaux, P., The discriminatory power of MALDI-TOF mass spectrometry to differentiate between isogenic teicoplanin-susceptible and teicoplanin-resistant strains of methicillin-resistant Staphylococcus aureus. FEMS Microbiol. Lett. 2006, 255, 233-239.
    • (2006) FEMS Microbiol. Lett. , vol.255 , pp. 233-239
    • Majcherczyk, P.A.1    McKenna, T.2    Moreillon, P.3    Vaudaux, P.4
  • 44
    • 79951678685 scopus 로고    scopus 로고
    • Tracing the transition of methicillin resistance in sub-populations of Staphylococcus aureus, using SELDI-TOF mass spectrometry and artificial neural network analysis
    • Shah, H. N., Rajakaruna, L., Ball, G., Misra, R. et al., Tracing the transition of methicillin resistance in sub-populations of Staphylococcus aureus, using SELDI-TOF mass spectrometry and artificial neural network analysis. Syst. Appl. Microbiol. 2011, 34, 81-86.
    • (2011) Syst. Appl. Microbiol. , vol.34 , pp. 81-86
    • Shah, H.N.1    Rajakaruna, L.2    Ball, G.3    Misra, R.4
  • 45
    • 78649634917 scopus 로고    scopus 로고
    • MALDI-TOF MS fingerprinting allows for discrimination of major methicillin-resistant Staphylococcus aureus lineages
    • Wolters, M., Rohde, H., Maier, T., Belmar-Campos, C. et al., MALDI-TOF MS fingerprinting allows for discrimination of major methicillin-resistant Staphylococcus aureus lineages. Int. J. Med. Microbiol. 2011, 301, 64-68.
    • (2011) Int. J. Med. Microbiol. , vol.301 , pp. 64-68
    • Wolters, M.1    Rohde, H.2    Maier, T.3    Belmar-Campos, C.4
  • 46
    • 84878520301 scopus 로고    scopus 로고
    • Analysis of the matrix-assisted laser desorption ionization-time of flight mass spectrum of Staphylococcus aureus identifies mutations that allow differentiation of the main clonal lineages
    • Josten, M., Reif, M., Szekat, C., Al-Sabti, N. et al., Analysis of the matrix-assisted laser desorption ionization-time of flight mass spectrum of Staphylococcus aureus identifies mutations that allow differentiation of the main clonal lineages. J. Clin. Microbiol. 2013, 51, 1809-1817.
    • (2013) J. Clin. Microbiol. , vol.51 , pp. 1809-1817
    • Josten, M.1    Reif, M.2    Szekat, C.3    Al-Sabti, N.4
  • 47
    • 84863487320 scopus 로고    scopus 로고
    • peptide biomarker discovery for identification of methicillin-resistant and vancomycin-intermediate Staphylococcus aureus strains by MALDI-TOF
    • Lu, J.-J., Tsai, F.-J., Ho, C.-M., Liu, Y.-C., Chen, C.-J., peptide biomarker discovery for identification of methicillin-resistant and vancomycin-intermediate Staphylococcus aureus strains by MALDI-TOF. Anal. Chem. 2012, 84, 5685-5692.
    • (2012) Anal. Chem. , vol.84 , pp. 5685-5692
    • Lu, J.-J.1    Tsai, F.-J.2    Ho, C.-M.3    Liu, Y.-C.4    Chen, C.-J.5
  • 48
    • 84867334585 scopus 로고    scopus 로고
    • Identical MALDI TOF MS-derived peak profiles in a pair of isogenic SCCmec-harboring and SCCmec-lacking strains of Staphylococcus aureus
    • Szabados, F., Kaase, M., Anders, A., Gatermann, S. G., Identical MALDI TOF MS-derived peak profiles in a pair of isogenic SCCmec-harboring and SCCmec-lacking strains of Staphylococcus aureus. J. Infect. 2012, 65, 400-405.
    • (2012) J. Infect. , vol.65 , pp. 400-405
    • Szabados, F.1    Kaase, M.2    Anders, A.3    Gatermann, S.G.4
  • 49
    • 84865180022 scopus 로고    scopus 로고
    • Use of matrix-assisted laser desorption ionization-time of flight mass spectrometry to identify vancomycin-resistant enterococci and investigate the epidemiology of an outbreak
    • Griffin, P. M., Price, G. R., Schooneveldt, J. M., Schlebusch, S. et al., Use of matrix-assisted laser desorption ionization-time of flight mass spectrometry to identify vancomycin-resistant enterococci and investigate the epidemiology of an outbreak. J. Clin. Microbiol. 2012, 50, 2918-2931.
    • (2012) J. Clin. Microbiol. , vol.50 , pp. 2918-2931
    • Griffin, P.M.1    Price, G.R.2    Schooneveldt, J.M.3    Schlebusch, S.4
  • 50
    • 79955525724 scopus 로고    scopus 로고
    • Differentiation of cfiA-negative and cfiA-positive Bacteroides fragilis isolates by matrix-assisted laser desorption ionization-time of flight mass spectrometry
    • Wybo, I., De Bel, A., Soetens, O., Echahidi, F. et al., Differentiation of cfiA-negative and cfiA-positive Bacteroides fragilis isolates by matrix-assisted laser desorption ionization-time of flight mass spectrometry. J. Clin. Microbiol. 2011, 49, 1961-1964.
    • (2011) J. Clin. Microbiol. , vol.49 , pp. 1961-1964
    • Wybo, I.1    De Bel, A.2    Soetens, O.3    Echahidi, F.4
  • 51
    • 80054721892 scopus 로고    scopus 로고
    • Differentiation of division I (cfiA-negative) and division II (cfiA-positive) Bacteroides fragilis strains by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry
    • Nagy, E., Becker, S., Sóki, J., Urbán, E., Kostrzewa, M., Differentiation of division I (cfiA-negative) and division II (cfiA-positive) Bacteroides fragilis strains by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. J. Med. Microbiol. 2011, 60, 1584-1590.
    • (2011) J. Med. Microbiol. , vol.60 , pp. 1584-1590
    • Nagy, E.1    Becker, S.2    Sóki, J.3    Urbán, E.4    Kostrzewa, M.5
  • 52
    • 70350246101 scopus 로고    scopus 로고
    • MALDI-TOF MS-based drug susceptibility testing of pathogens: the example of Candida albicans and fluconazole
    • Marinach, C., Alanio, A., Palous, M., Kwasek, S. et al., MALDI-TOF MS-based drug susceptibility testing of pathogens: the example of Candida albicans and fluconazole. Proteomics 2009, 9, 4627-4631.
    • (2009) Proteomics , vol.9 , pp. 4627-4631
    • Marinach, C.1    Alanio, A.2    Palous, M.3    Kwasek, S.4
  • 53
    • 84862736700 scopus 로고    scopus 로고
    • Use of matrix-assisted laser desorption ionization-time of flight mass spectrometry for caspofungin susceptibility testing of Candida and Aspergillus species
    • De Carolis, E., Vella, A., Florio, A. R., Posteraro, P. et al., Use of matrix-assisted laser desorption ionization-time of flight mass spectrometry for caspofungin susceptibility testing of Candida and Aspergillus species. J. Clin. Microbiol. 2012, 50, 2479-2483.
    • (2012) J. Clin. Microbiol. , vol.50 , pp. 2479-2483
    • De Carolis, E.1    Vella, A.2    Florio, A.R.3    Posteraro, P.4
  • 54
    • 84882755681 scopus 로고    scopus 로고
    • Rapid antifungal susceptibility testing by matrix-assisted laser desorption ionization time-of-flight mass spectrometry analysis
    • Vella, A., Carolis, E. D., Vaccaro, L., Posteraro, P. et al., Rapid antifungal susceptibility testing by matrix-assisted laser desorption ionization time-of-flight mass spectrometry analysis. J. Clin. Microbiol. 2013, 51, 2964-2969.
    • (2013) J. Clin. Microbiol. , vol.51 , pp. 2964-2969
    • Vella, A.1    Carolis, E.D.2    Vaccaro, L.3    Posteraro, P.4
  • 55
    • 80052197551 scopus 로고    scopus 로고
    • Carbapenemase activity detection by matrix-assisted laser desorption ionization-time of flight mass spectrometry
    • Hrabák, J., Walková, R., Studentová, V., Chudácková, E., Bergerová, T., Carbapenemase activity detection by matrix-assisted laser desorption ionization-time of flight mass spectrometry. J. Clin. Microbiol. 2011, 49, 3222-3227.
    • (2011) J. Clin. Microbiol. , vol.49 , pp. 3222-3227
    • Hrabák, J.1    Walková, R.2    Studentová, V.3    Chudácková, E.4    Bergerová, T.5
  • 56
    • 84857382388 scopus 로고    scopus 로고
    • Matrix-assisted laser desorption ionization-time of flight mass spectrometry-based functional assay for rapid detection of resistance against β-lactam antibiotics
    • Sparbier, K., Schubert, S., Weller, U., Boogen, C., Kostrzewa, M., Matrix-assisted laser desorption ionization-time of flight mass spectrometry-based functional assay for rapid detection of resistance against β-lactam antibiotics. J. Clin. Microbiol. 2012, 50, 927-937.
    • (2012) J. Clin. Microbiol. , vol.50 , pp. 927-937
    • Sparbier, K.1    Schubert, S.2    Weller, U.3    Boogen, C.4    Kostrzewa, M.5
  • 57
    • 80052230956 scopus 로고    scopus 로고
    • Using matrix-assisted laser desorption ionization-time of flight mass spectrometry to detect carbapenem resistance within 1 to 2.5 hours
    • Burckhardt, I., Zimmermann, S., Using matrix-assisted laser desorption ionization-time of flight mass spectrometry to detect carbapenem resistance within 1 to 2.5 hours. J. Clin. Microbiol. 2011, 49, 3321-3324.
    • (2011) J. Clin. Microbiol. , vol.49 , pp. 3321-3324
    • Burckhardt, I.1    Zimmermann, S.2
  • 58
    • 36549078518 scopus 로고    scopus 로고
    • Minimum inhibitory concentration (MIC) analysis and susceptibility testing of MRSA
    • Bou, G., Minimum inhibitory concentration (MIC) analysis and susceptibility testing of MRSA. Methods Mol. Biol. Clifton NJ 2007, 391, 29-49.
    • (2007) Methods Mol. Biol. Clifton NJ , vol.391 , pp. 29-49
    • Bou, G.1
  • 59
    • 77955435461 scopus 로고    scopus 로고
    • Comparison of BD Phoenix, Vitek 2, and MicroScan automated systems for detection and inference of mechanisms responsible for carbapenem resistance in Enterobacteriaceae
    • Woodford, N., Eastaway, A. T., Ford, M., Leanord, A. et al., Comparison of BD Phoenix, Vitek 2, and MicroScan automated systems for detection and inference of mechanisms responsible for carbapenem resistance in Enterobacteriaceae. J. Clin. Microbiol. 2010, 48, 2999-3002.
    • (2010) J. Clin. Microbiol. , vol.48 , pp. 2999-3002
    • Woodford, N.1    Eastaway, A.T.2    Ford, M.3    Leanord, A.4
  • 60
    • 84876776956 scopus 로고    scopus 로고
    • Optimized method for acinetobacter species carbapenemase detection and identification by matrix-assisted laser desorption ionization-time of flight mass spectrometry
    • Alvarez-Buylla, A., Picazo, J. J., Culebras, E., Optimized method for acinetobacter species carbapenemase detection and identification by matrix-assisted laser desorption ionization-time of flight mass spectrometry. J. Clin. Microbiol. 2013, 51, 1589-1592.
    • (2013) J. Clin. Microbiol. , vol.51 , pp. 1589-1592
    • Alvarez-Buylla, A.1    Picazo, J.J.2    Culebras, E.3
  • 61
    • 84857129819 scopus 로고    scopus 로고
    • Rapid detection of carbapenem resistance in Acinetobacter baumannii using matrix-assisted laser desorption ionization-time of flight mass spectrometry
    • Kempf, M., Bakour, S., Flaudrops, C., Berrazeg, M. et al., Rapid detection of carbapenem resistance in Acinetobacter baumannii using matrix-assisted laser desorption ionization-time of flight mass spectrometry. PloS One 2012, 7, e31676.
    • (2012) PloS One , vol.7
    • Kempf, M.1    Bakour, S.2    Flaudrops, C.3    Berrazeg, M.4
  • 62
    • 84862732255 scopus 로고    scopus 로고
    • Detection of NDM-1, VIM-1, KPC, OXA-48, and OXA-162 carbapenemases by matrix-assisted laser desorption ionization-time of flight mass spectrometry
    • Hrabák, J., Studentová, V., Walková, R., Zemlicková, H. et al., Detection of NDM-1, VIM-1, KPC, OXA-48, and OXA-162 carbapenemases by matrix-assisted laser desorption ionization-time of flight mass spectrometry. J. Clin. Microbiol. 2012, 50, 2441-2443.
    • (2012) J. Clin. Microbiol. , vol.50 , pp. 2441-2443
    • Hrabák, J.1    Studentová, V.2    Walková, R.3    Zemlicková, H.4
  • 63
    • 33750347317 scopus 로고    scopus 로고
    • Localization of noncovalent complexes in MALDI-preparations by CLSM
    • Horneffer, V., Strupat, K., Hillenkamp, F., Localization of noncovalent complexes in MALDI-preparations by CLSM. J. Am. Soc. Mass Spectrom. 2006, 17, 1599-1604.
    • (2006) J. Am. Soc. Mass Spectrom. , vol.17 , pp. 1599-1604
    • Horneffer, V.1    Strupat, K.2    Hillenkamp, F.3
  • 64
    • 84855522034 scopus 로고    scopus 로고
    • Characterization of β-lactamase enzyme activity in bacterial lysates using MALDI-mass spectrometry
    • Hooff, G. P., van Kampen, J. J. A., Meesters, R. J. W., van Belkum, A. et al., Characterization of β-lactamase enzyme activity in bacterial lysates using MALDI-mass spectrometry. J. Proteome Res. 2012, 11, 79-84.
    • (2012) J. Proteome Res. , vol.11 , pp. 79-84
    • Hooff, G.P.1    van Kampen, J.J.A.2    Meesters, R.J.W.3    van Belkum, A.4
  • 65
    • 0038168181 scopus 로고    scopus 로고
    • Evaluation of the NCCLS extended-spectrum beta-lactamase confirmation methods for Escherichia coli with isolates collected during Project ICARE
    • Tenover, F. C., Raney, P. M., Williams, P. P., Rasheed, J. K. et al., Evaluation of the NCCLS extended-spectrum beta-lactamase confirmation methods for Escherichia coli with isolates collected during Project ICARE. J. Clin. Microbiol. 2003, 41, 3142-3146.
    • (2003) J. Clin. Microbiol. , vol.41 , pp. 3142-3146
    • Tenover, F.C.1    Raney, P.M.2    Williams, P.P.3    Rasheed, J.K.4
  • 66
    • 84858601716 scopus 로고    scopus 로고
    • Phenotypic screening of carbapenemases and associated β-lactamases in carbapenem-resistant Enterobacteriaceae
    • Birgy, A., Bidet, P., Genel, N., Doit, C. et al., Phenotypic screening of carbapenemases and associated β-lactamases in carbapenem-resistant Enterobacteriaceae. J. Clin. Microbiol. 2012, 50, 1295-1302.
    • (2012) J. Clin. Microbiol. , vol.50 , pp. 1295-1302
    • Birgy, A.1    Bidet, P.2    Genel, N.3    Doit, C.4
  • 67
    • 80051913896 scopus 로고    scopus 로고
    • A simple test for the detection of KPC and metallo-β-lactamase carbapenemase-producing Pseudomonas aeruginosa isolates with the use of meropenem disks supplemented with aminophenylboronic acid, dipicolinic acid and cloxacillin
    • Pasteran, F., Veliz, O., Faccone, D., Guerriero, L. et al., A simple test for the detection of KPC and metallo-β-lactamase carbapenemase-producing Pseudomonas aeruginosa isolates with the use of meropenem disks supplemented with aminophenylboronic acid, dipicolinic acid and cloxacillin. Clin. Microbiol. Infect. Off. Publ. Eur. Soc. Clin. Microbiol. Infect. Dis. 2011, 17, 1438-1441.
    • (2011) Clin. Microbiol. Infect. Off. Publ. Eur. Soc. Clin. Microbiol. Infect. Dis. , vol.17 , pp. 1438-1441
    • Pasteran, F.1    Veliz, O.2    Faccone, D.3    Guerriero, L.4
  • 68
    • 77954187385 scopus 로고    scopus 로고
    • Inhibitor-based methods for the detection of KPC carbapenemase-producing Enterobacteriaceae in clinical practice by using boronic acid compounds
    • Pournaras, S., Poulou, A., Tsakris, A., Inhibitor-based methods for the detection of KPC carbapenemase-producing Enterobacteriaceae in clinical practice by using boronic acid compounds. J. Antimicrob. Chemother. 2010, 65, 1319-1321.
    • (2010) J. Antimicrob. Chemother. , vol.65 , pp. 1319-1321
    • Pournaras, S.1    Poulou, A.2    Tsakris, A.3
  • 69
    • 73949146997 scopus 로고    scopus 로고
    • Mass spectrometry tools for the classification and identification of bacteria
    • Sauer, S., Kliem, M., Mass spectrometry tools for the classification and identification of bacteria. Nat. Rev. Microbiol. 2010, 8, 74-82.
    • (2010) Nat. Rev. Microbiol. , vol.8 , pp. 74-82
    • Sauer, S.1    Kliem, M.2
  • 71
    • 33745270570 scopus 로고    scopus 로고
    • Mechanisms of antimicrobial resistance in bacteria
    • discussion S62-S70.
    • Tenover, F. C., Mechanisms of antimicrobial resistance in bacteria. Am. J. Med. 2006, 119, S3-S10; discussion S62-S70.
    • (2006) Am. J. Med. , vol.119
    • Tenover, F.C.1
  • 72
    • 34247568394 scopus 로고    scopus 로고
    • Efflux pumps as antimicrobial resistance mechanisms
    • Poole, K., Efflux pumps as antimicrobial resistance mechanisms. Ann. Med. 2007, 39, 162-176.
    • (2007) Ann. Med. , vol.39 , pp. 162-176
    • Poole, K.1
  • 73
    • 84869212340 scopus 로고    scopus 로고
    • Rapid identification of carbapenemase types in Enterobacteriaceae and Pseudomonas spp. by using a biochemical test
    • Dortet, L., Poirel, L., Nordmann, P., Rapid identification of carbapenemase types in Enterobacteriaceae and Pseudomonas spp. by using a biochemical test. Antimicrob. Agents Chemother. 2012, 56, 6437-6440.
    • (2012) Antimicrob. Agents Chemother. , vol.56 , pp. 6437-6440
    • Dortet, L.1    Poirel, L.2    Nordmann, P.3
  • 74
    • 84859966515 scopus 로고    scopus 로고
    • Rapid detection of ampicillin resistance in Escherichia coli by quantitative mass spectrometry
    • Grundt, A., Findeisen, P., Miethke, T., Jäger, E. et al., Rapid detection of ampicillin resistance in Escherichia coli by quantitative mass spectrometry. J. Clin. Microbiol. 2012, 50, 1727-1729.
    • (2012) J. Clin. Microbiol. , vol.50 , pp. 1727-1729
    • Grundt, A.1    Findeisen, P.2    Miethke, T.3    Jäger, E.4
  • 75
    • 84867557710 scopus 로고    scopus 로고
    • Rapid detection of carbapenemase-producing Pseudomonas spp
    • Dortet, L., Poirel, L., Nordmann, P., Rapid detection of carbapenemase-producing Pseudomonas spp. J. Clin. Microbiol. 2012, 50, 3773-3776.
    • (2012) J. Clin. Microbiol. , vol.50 , pp. 3773-3776
    • Dortet, L.1    Poirel, L.2    Nordmann, P.3
  • 76
    • 0030792311 scopus 로고    scopus 로고
    • Bacterial resistance to aminoglycoside antibiotics
    • Davies, J., Wright, G. D., Bacterial resistance to aminoglycoside antibiotics. Trends Microbiol. 1997, 5, 234-240.
    • (1997) Trends Microbiol. , vol.5 , pp. 234-240
    • Davies, J.1    Wright, G.D.2
  • 77
    • 22144476125 scopus 로고    scopus 로고
    • Bacterial resistance to antibiotics: enzymatic degradation and modification
    • Wright, G. D., Bacterial resistance to antibiotics: enzymatic degradation and modification. Adv. Drug Deliv. Rev. 2005, 57, 1451-1470.
    • (2005) Adv. Drug Deliv. Rev. , vol.57 , pp. 1451-1470
    • Wright, G.D.1
  • 78
    • 75649101296 scopus 로고    scopus 로고
    • Exploring the substrate promiscuity of drug-modifying enzymes for the chemoenzymatic generation of N-acylated aminoglycosides
    • Green, K. D., Chen, W., Houghton, J. L., Fridman, M., Garneau-Tsodikova, S., Exploring the substrate promiscuity of drug-modifying enzymes for the chemoenzymatic generation of N-acylated aminoglycosides. Chembiochem Eur. J. Chem. Biol. 2010, 11, 119-126.
    • (2010) Chembiochem Eur. J. Chem. Biol. , vol.11 , pp. 119-126
    • Green, K.D.1    Chen, W.2    Houghton, J.L.3    Fridman, M.4    Garneau-Tsodikova, S.5


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