The Rapid Identification of Intact Microorganisms Using Mass Spectrometry

Nature Biotechnology

Volumn 14, Issue 11, 1996, Pages 1584-1586

  Claydon, Martin A ^a   Davey, Simon N ^a   Edwards Jones, Valerie ^a   Gordon, Derek B ^a  

^a MANCHESTER METROPOLITAN UNIVERSITY   (United Kingdom)

Author keywords

MALDI TOF; Mass spectrometry; Microorganisms

Indexed keywords

ANTIBIOTIC RESISTANCE; BACTERIAL COLONIZATION; BACTERIUM CULTURE; BACTERIUM IDENTIFICATION; DIAGNOSTIC ACCURACY; ESCHERICHIA COLI; KLEBSIELLA AEROGENES; MASS SPECTROMETRY; MYCOBACTERIUM SMEGMATIS; NONHUMAN; PRIORITY JOURNAL; REVIEW; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS EPIDERMIDIS; STAPHYLOCOCCUS SAPROPHYTICUS; STRAIN DIFFERENCE;

COUMARIC ACIDS; DRUG RESISTANCE, MICROBIAL; GRAM-NEGATIVE BACTERIA; GRAM-POSITIVE BACTERIA; REPRODUCIBILITY OF RESULTS; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; KLEBSIELLA AEROGENES; MYCOBACTERIUM SMEGMATIS; NEGIBACTERIA; POSIBACTERIA; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS EPIDERMIDIS; STAPHYLOCOCCUS SAPROPHYTICUS;

EID: 0029998033     PISSN: 10870156     EISSN: 15461696     Source Type: Journal    
DOI: 10.1038/nbt1196-1584     Document Type: Article

References (16)

1. Morse, A. 1995. Classification of bacteria, Chapter 3, pp. 35-43 in Medical microbiology, 20th ed. Jawetz, E., Melnick, J.L., and Adelberg, E.A. (eds.). Lange Medical, London.
2. Gallagher, R.T., Davey, S.N., and Derrick, P.J. 1996. pp. 329-364 in Biomedical applications of spectroscopy advances in spectroscopy, Vol. 25. Clark, R.J.H. and Hester, R.E. (eds.). John Wiley and Sons, Chichester, UK.
3. Fenselau, C. (ed.). 1994. Mass spectrometry for the characterization of microorganisms, ACS symposium series, Vol. 541. ACS, Washington, DC.
4. Heller, D.N., Fenselau, C., Cotter, R.J., Demirev, R., Olthoff, J.K., Honovich, J., et al. 1987. Mass spectral analysis of complex lipids desorbed directly from Iyophilised membranes and cells. Biochem. Biophys. Res. Com. 142:194-199.
5. Matsuo, T., Caprioli, R.M., and Gross, M.L., (eds.). 1994. Biological mass spectrometry. John Wiley and Sons, Chichester, UK.
6. Hillenkamp, F., Karas, M., Beavis, R.C., and Chait, B.T. 1991. Matrix assisted laser desorption ionization mass spectrometry of biopolymers. Anal. Chem. 63: 1193A-1202A.
7. Cotter, R.J. 1992. Time of flight mass spectrometry for the structural analysis of biological molecules. Anal. Chem. 64:1027A-1039A.
8. Liang, X., Zheng, K., Qian, M.G., and Lubman, D.M. 1996. Determination of bacterial protein profiles by matrix assisted laser desorption ionization mass spectrometry with high performance liquid chromatography. Rapid Commun. Mass Spectrom. 10:1219-1226.
9. Krishnamurthy, T., Ross, P.L., and Rajamani, U. 1996. Detection of pathogenic and non-pathogenic bacteria by matrix assisted laser desorption ionization time of flight mass spectrometry. Rapid Commun. Mass Spectrom. 10:883-888.
10. Holland, R.D., Wilkes, J.G., Rafii, F., Sutherland, J.B., Persons, C.C., Voorhees, K.J., et al. 1996. Rapid identification of intact whole bacteria based on spectral patterns using matrix assisted laser desorption ionization with time of flight mass spectrometry. Rapid Commun. Mass Spectrom. 10:1227-1232.
11. Ewing, W.H. 1986. Edwards and Ewings identification of enterobacteriacae, 4th ed., Elsevier, Amsterdam.
12. Zubay, G. 1993. Biochemistry, 3rd ed., pp. 138-160. Wm. C. Brown, Dubuque, IA.
13. Butler, W.R., Jost Jr., K.C., and Kilburn, J.O. 1991. Identification of mycobacteria by high performance liquid chromatography. J. Clin. Microbiol. 29:2468-2472.
14. Hagen, S.R. and Thompson, J.D. 1995. Analysis of mycolic acids by high performance liquid chromatography and fluorimetric detection—applications for the identification of mycobacteria in clinical samples. J. Chromatog. A. 693:167-172.
15. Dobson, G., Minnikin, D.E., Minnikin, S.M., Parlett, J.H., Goodfellow, M., Ridell, M. 1985. Systematic analysis of complex mycobacterial liquids, pp. 237-265 in Chemical Methods in Bacterial Systematics, Society of Applied Bacteriology, UK.
16. Brennan, P.J. and Nikaido, H. 1995. The envelope of mycobacteria. Ann. Rev. Biochem. 64:29-63.