Rapid detection of ampicillin resistance in Escherichia coli by quantitative mass spectrometry

Journal of Clinical Microbiology

Volumn 50, Issue 5, 2012, Pages 1727-1729

  Grundt, A ^a   Findeisen, P ^a   Miethke, T ^b   Jager E ^a   Ahmad Nejad, P ^a   Neumaier, M ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMPICILLIN; EXTENDED SPECTRUM BETA LACTAMASE;

ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL GROWTH; BACTERIAL STRAIN; BACTERIUM DETECTION; BACTERIUM ISOLATE; CLINICAL EFFECTIVENESS; ESCHERICHIA COLI; MASS SPECTROMETRY; NONHUMAN; PENICILLIN RESISTANCE; PHENOTYPE; PRIORITY JOURNAL; QUANTITATIVE STUDY; SIGNAL NOISE RATIO; TURNAROUND TIME;

AMPICILLIN; AMPICILLIN RESISTANCE; ANTI-BACTERIAL AGENTS; ESCHERICHIA COLI; HUMANS; MASS SPECTROMETRY; MICROBIAL SENSITIVITY TESTS; TIME FACTORS;

EID: 84859966515     PISSN: 00951137     EISSN: 1098660X     Source Type: Journal    
DOI: 10.1128/JCM.00047-12     Document Type: Article

References (12)

1. Beekmann SE, Diekema DJ, Chapin KC, Doern GV. 2003. Effects of rapid detection of bloodstream infections on length of hospitalization and hospital charges. J. Clin. Microbiol. 41:3119-3125. (Pubitemid 36842309)
2. Coleman RW, Rodondi LC, Kaubisch S, Granzella NB, O'Hanley PD. 1991. Cost-effectiveness of prospective and continuous parenteral antibiotic control: experience at the Palo Alto Veterans Affairs Medical Center from 1987 to 1989. Am. J. Med. 90:439-444.
3. Fraser A, et al. 2006. Benefit of appropriate empirical antibiotic treatment: thirty-day mortality and duration of hospital stay. Am. J. Med. 119:970-976. (Pubitemid 44634308)
4. Gherardi G, et al. 2011. Comparative evaluation of the Vitek-2 Compact and Phoenix systems for rapid identification and antibiotic susceptibility testing directly from blood cultures of Gram-negative and Gram-positive isolates. Diagn. Microbiol. Infect. Dis. 72:20-31.
5. Goldmann DA, et al. 1996. Strategies to prevent and control the emergence and spread of antimicrobial-resistant microorganisms in hospitals. A challenge to hospital leadership. JAMA 275:234-240. (Pubitemid 26028565)
6. Hooff GP, et al. 2011. Characterization of beta-lactamase enzyme activity in bacterial lysates using MALDI-mass spectrometry. J. Proteome Res. 11:79-84.
7. Kerremans JJ, et al. 2008. Rapid identification and antimicrobial susceptibility testing reduce antibiotic use and accelerate pathogen-directed antibiotic use. J. Antimicrob. Chemother. 61:428-435.
8. Leibovici L, et al. 1998. The benefit of appropriate empirical antibiotic treatment in patients with bloodstream infection. J. Intern. Med. 244:379-386. (Pubitemid 28513125)
9. Lodise TP, McKinnon PS, Swiderski L, Rybak MJ. 2003. Outcomes analysis of delayed antibiotic treatment for hospital-acquired Staphylococcus aureus bacteremia. Clin. Infect. Dis. 36:1418-1423. (Pubitemid 36702876)
10. McGowan JE, Jr. 1994. Do intensive hospital antibiotic control programs prevent the spread of antibiotic resistance? Infect. Control Hosp. Epidemiol. 15:478-483.
11. Pfaller MA, Segreti J. 2006. Overview of the epidemiological profile and laboratory detection of extended-spectrum beta-lactamases. Clin. Infect. Dis. 42(Suppl 4):S153-S163.
12. Tumbarello M, et al. 2010. Costs of bloodstream infections caused by Escherichia coli and influence of extended-spectrum-beta-lactamase production and inadequate initial antibiotic therapy. Antimicrob. Agents Chemother. 54:4085-4091.