Bacteria clustering by polymers induces the expression of quorum-sensing-controlled phenotypes

Nature Chemistry

Volumn 5, Issue 12, 2013, Pages 1058-1065

  Lui, Leong T ^a   Xue, Xuan ^a   Sui, Cheng ^a   Brown, Alan ^a   Pritchard, David I ^a   Halliday, Nigel ^a   Winzer, Klaus ^a   Howdle, Steven M ^a   Fernandez Trillo, Francisco ^a   Krasnogor, Natalio ^b   Alexander, Cameron ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^b NEWCASTLE UNIVERSITY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

POLYMER;

ARTICLE; BACTERIUM; BACTERIUM ADHERENCE; BIOLOGICAL MODEL; CHEMISTRY; CYTOLOGY; DRUG EFFECT; LUMINESCENCE; METABOLISM; PHENOTYPE; PHYSIOLOGY; QUORUM SENSING; VIBRIO; BACTERIA; DRUG EFFECTS;

BACTERIA; BACTERIAL ADHESION; LUMINESCENCE; LUMINESCENT MEASUREMENTS; MODELS, BIOLOGICAL; PHENOTYPE; POLYMERS; QUORUM SENSING; VIBRIO;

EID: 84890032059     PISSN: 17554330     EISSN: 17554349     Source Type: Journal    
DOI: 10.1038/nchem.1793     Document Type: Article

References (50)

1. Clatworthy, A. E., Pierson, E. & Hung, D. T. Targeting virulence: A new paradigm for antimicrobial therapy. Nature Chem. Biol. 3, 541-548 (2007
2. Nathan, C. Fresh approaches to anti-infective therapies. Sci. Transl. Med. 4, 140sr2 (2012
3. Hancock, R. E. W., Nijnik, A. & Philpott, D. J. Modulating immunity as a therapy for bacterial infections. Nature Rev. Microbiol. 10, 243-254 (2012
4. Wei, P. et al. Bacterial virulence proteins as tools to rewire kinase pathways in yeast and immune cells. Nature 488, 384-388 (2012
5. Klemm, P., Vejborg, R. M. & Hancock, V. Prevention of bacterial adhesion. Appl. Microb. Biotechnol. 88, 451-459 (2010
6. Bricarello, D. A., Patel, M. A. & Parikh, A. N. Inhibiting host-pathogen interactions using membrane-based nanostructures. Trends Biotechnol. 30, 323-330 (2012
7. Kaufmann, G. F., Park, J. & Janda, K. D. Bacterial quorum sensing: A new target for anti-infective immunotherapy. Exp. Opin. Biol. Ther. 8, 719-724 (2008
8. Park, J. et al. Infection control by antibody disruption of bacterial quorum sensing signaling. Chem. Biol. 14, 1119-1127 (2007
9. Hancock, R. E. W. & Sahl, H-G. Antimicrobial and host-defense peptides as new anti-infective therapeutic strategies. Nature Biotechnol. 24, 1551-1557 (2006
10. Nederberg, F. et al. Biodegradable nanostructures with selective lysis of microbial membranes. Nature Chem. 3, 409-414 (2011
11. Liu, L. et al. Self-Assembled cationic peptide nanoparticles as an efficient antimicrobial agent. Nature Nanotech. 4, 457-463 (2009
12. Alexander, C., Pasparakis, G. & Cockayne, A. Control of bacterial aggregation by thermoresponsive glycopolymers. J. Am. Chem.Soc. 129, 11014-11015 (2007
13. Shepherd, J. et al. Hyperbranched poly(NIPAM) polymers modified with antibiotics for the reduction of bacterial burden in infected human tissue engineered skin. Biomaterials 32, 258-267 (2011
14. Lee, D-W., Kim, T., Park, I-S., Huang, Z. & Lee, M. Multivalent nanofibers of a controlled length: Regulation of bacterial cell agglutination. J. Am. Chem. Soc 134, 14722-14725 (2012
15. Rai, P. et al. Statistical pattern matching facilitates the design of polyvalent inhibitors of anthrax and cholera toxins. Nature Biotechnol. 24, 582-586 (2006
16. Piletska, E. V. et al. Attenuation of Vibrio fischeri quorum sensing using rationally designed polymers. Biomacromolecules 11, 975-980 (2010
17. Bush, K. et al. Tackling antibiotic resistance. Nature Rev. Microbiol. 9, 894-896 (2011
18. Garner, A. L. et al. A multivalent probe for AI-2 quorum-sensing receptors. J. Am. Chem. Soc. 133, 15934-15937 (2011
19. Cossart, P. & Sansonetti, P. J. Bacterial invasion: The paradigms of enteroinvasive pathogens. Science 304, 242-248 (2004
20. Hook, A. L. et al. Combinatorial discovery of polymers resistant to bacterial attachment. Nature Biotechnol. 30, 868-875 (2012
21. Smith, R. S. et al. Vascular catheters with a nonleaching poly-sulfobetaine surface modification reduce thrombus formation and microbial attachment. Sci. Transl. Med. 4, 153ra132 (2012
22. Epstein, A. K., Wong, T-S., Belisle, R. A., Boggs, E. M. & Aizenberg, J. Liquid-infused structured surfaces with exceptional anti-biofouling performance. Proc. Natl Acad. Sci. USA 109, 13182-13187 (2012
23. Kastrup, C. J. et al. Spatial localization of bacteria controls coagulation of human blood by 'quorum acting'. Nature Chem. Biol 4, 742-750 (2008
24. Carnes, E. C. et al. Confinement-induced quorum sensing of individual Staphylococcus aureus bacteria. Nature Chem. Biol. 6, 41-45 (2010
25. Alberghini, S. et al. Consequences of relative cellular positioning on quorum sensing and bacterial cell-To-cell communication. FEMS Microbiol. Lett. 292, 149-161 (2009
26. Goryachev, A. B. Understanding bacterial cell-cell communication with computational modeling. Chem. Rev. 111, 238-250 (2011
27. Flickinger, S. T. et al. Quorum sensing between Pseudomonas aeruginosa biofilms accelerates cell growth. J. Am. Chem. Soc. 133, 5966-5975 (2011
28. Boedicker, J. Q., Vincent, M. E. & Ismagilov, R. F. Microfluidic confinement of single cells of bacteria in small volumes initiates high-density behavior of quorum sensing and growth and reveals its variability. Angew. Chem. Int. Ed. 48, 5908-5911 (2009
29. Lowery, C. A., Dickerson, T. J. & Janda, K. D. Interspecies and interkingdom communication mediated by bacterial quorum sensing. Chem. Soc. Rev. 37, 1337-1346 (2008
30. Atkinson, S. & Williams, P. Quorum sensing and social networking in the microbial world. J. R. Soc. Interface 6, 959-978 (2009
31. Miller, M. B. & Bassler, B. L. Quorum sensing in bacteria. Annu. Rev. Microbiol. 55, 165-199 (2001
32. Camilli, A. & Bassler, B. L. Bacterial small-molecule signaling pathways. Science 311, 1113-1116 (2006
33. Williams, P. Quorum sensing, communication and cross-kingdom signaling in the bacterial world. Microbiology 153, 3923-3938 (2007
34. Williams, P., Winzer, K., Chan, W. C. & Camara, M. Look who's talking: Communication and quorum sensing in the bacterial world. Phil. Trans. R. Soc. B 362, 1119-1134 (2007
35. Antunes, L. C. M. & Ferreira, R. B. R. Intercellular communication in bacteria. Crit. Rev. Microbiol. 35, 69-80 (2009
36. Fuqua, C. & Greenberg, E. P. Listening in on bacteria: Acyl-homoserine lactone signaling. Nature Rev. Mol. Cell Biol. 3, 685-695 (2002
37. Redfield, R J. Is quorum sensing a side effect of diffusion sensing? Trends Microbiol. 10, 365-370 (2002
38. Federle, M. J. & Bassler, B. L. Interspecies communication in bacteria. J. Clin. Invest. 112, 1291-1299 (2003
39. Xue, X. et al. Synthetic polymers for simultaneous bacterial sequestration and quorum sense interference. Angew. Chem. Int. Ed. 50, 9852-9856 (2011
40. Barnard, A. M. L. et al. Quorum sensing, virulence and secondary metabolite production in plant soft-rotting bacteria. Phil. Trans. R. Soc. B 362, 1165-1183 (2007
41. Fineran, P. C., Slater, H., Everson, L., Hughes, K. & Salmond, G. P. C. Biosynthesis of tripyrrole and beta-lactam secondary metabolites in Serratia: Integration of quorum sensing with multiple new regulatory components in the control of prodigiosin and carbapenem antibiotic production. Mol. Microbiol. 56, 1495-1517 (2005
42. Kenawy, E-R., Worley, S. D. & Broughton, R. The chemistry and applications of antimicrobial polymers: A state-of-The-Art review. Biomacromolecules 8, 1359-1384 (2007
43. Engler, A. C. et al. Emerging trends in macromolecular antimicrobials to fight multi-drug-resistant infections. Nano Today 7, 201-222 (2012
44. Winson, M. K. et al. Construction and analysis of luxCDABE-based plasmid sensors for investigating N-Acyl homoserine lactone-mediated quorum sensing. FEMS Microbiol. Lett. 163, 185-192 (1998
45. Swift, S. et al. Quorum sensing in Aeromonas hydrophila and Aeromonas salmonicida: Identification of the LuxRI homologs AhyRI and AsaRI and their cognate N-Acylhomoserine lactone signal molecules. J. Bacteriol. 179, 5271-5281 (1997
46. Pearson, J. P. et al. Structure of the autoinducer required for expression of Pseudomonas aeruginosa virulence genes. Proc. Natl Acad. Sci. USA 91, 197-201 (1994
47. Winson, M. K. et al. Multiple N-Acyl-L-homoserine lactone signal molecules regulate production of virulence determinants and secondary metabolites in Pseudomonas aeruginosa. Proc. Natl Acad. Sci. USA 92, 9427-9431 (1995
48. Diggle, S. P. et al. The Pseudomonas aeruginosa 4-quinolone signal molecules HHQ and PQS play multifunctional roles in quorum sensing and iron entrapment. Chem. Biol. 14, 87-96 (2007
49. Pesci, E. C. et al. Quinolone signaling in the cell-To-cell communication system of Pseudomonas aeruginosa. Proc. Natl Acad. Sci. USA 96, 11229-11234 (1999
50. Krasnogor, N. et al. An appealing computational mechanism drawn from bacterial quorum sensing. Bull. Eur. Assoc. Theor. Comput. Sci. 85, 135-148 (2005