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Volumn 18, Issue 3-4, 2013, Pages 333-343

Impact of obesity on development and progression of mammary tumors in preclinical models of breast cancer

Author keywords

Animal models; Aromatase; Breast cancer; High fat diets; Leptin; Mammary tumors; Mice; Obesity; Obesity prone; Overweight; Rats

Indexed keywords

ESTROGEN; ESTROGEN RECEPTOR; EVEROLIMUS; FAT; GROWTH FACTOR; INSULIN; LEPTIN; LEPTIN RECEPTOR; METHYLNITROSOUREA; PROGESTERONE RECEPTOR; SOMATOMEDIN C;

EID: 84890016588     PISSN: 10833021     EISSN: 15737039     Source Type: Journal    
DOI: 10.1007/s10911-013-9300-x     Document Type: Article
Times cited : (25)

References (79)
  • 1
    • 78449271818 scopus 로고    scopus 로고
    • Obesity and breast cancer: Status of leptin and adiponectin in pathological processes
    • 20821253 10.1007/s10555-010-9252-1 1:CAS:528:DC%2BC3cXhtlant7zM
    • Grossmann ME, Ray A, Nkhata KJ, Malakhov DA, Rogozina OP, Dogan S, et al. Obesity and breast cancer: status of leptin and adiponectin in pathological processes. Cancer Metastasis Rev. 2010;29:641-53.
    • (2010) Cancer Metastasis Rev. , vol.29 , pp. 641-653
    • Grossmann, M.E.1    Ray, A.2    Nkhata, K.J.3    Malakhov, D.A.4    Rogozina, O.P.5    Dogan, S.6
  • 2
    • 0030984458 scopus 로고    scopus 로고
    • The role of body mass index in the relative risk of developing premenopausal versus postmenopausal breast cancer
    • 9316608 10.3181/00379727-216-44153B 1:CAS:528:DyaK2sXmtlOmsbg%3D
    • Cleary MP, Maihle NJ. The role of body mass index in the relative risk of developing premenopausal versus postmenopausal breast cancer. Proc Soc Exp Biol Med. 1997;216:28-43.
    • (1997) Proc. Soc. Exp. Biol. Med. , vol.216 , pp. 28-43
    • Cleary, M.P.1    Maihle, N.J.2
  • 3
    • 77950861428 scopus 로고    scopus 로고
    • Interaction between menopausal status and obesity in affecting breast cancer risk
    • 20181446 10.1016/j.maturitas.2010.01.019
    • Rose DP, Vona-Davis L. Interaction between menopausal status and obesity in affecting breast cancer risk. Maturitas. 2010;66:33-8.
    • (2010) Maturitas , vol.66 , pp. 33-38
    • Rose, D.P.1    Vona-Davis, L.2
  • 4
    • 84871783047 scopus 로고    scopus 로고
    • Obesity as a risk factor for triple-negative breast cancers: A systematic review and meta-analysis
    • 23179600 10.1007/s10549-012-2339-3
    • Pierobon M, Frankenfeld CL. Obesity as a risk factor for triple-negative breast cancers: a systematic review and meta-analysis. Breast Cancer Res Treat. 2013;137:307-14.
    • (2013) Breast Cancer Res. Treat. , vol.137 , pp. 307-314
    • Pierobon, M.1    Frankenfeld, C.L.2
  • 5
    • 84876429890 scopus 로고    scopus 로고
    • Obesity/weight gain and breast cancer risk: Findings from the Japan Collaborative Cohort Study for the Evaluation of Cancer Risk
    • 23438695 10.2188/jea.JE20120102
    • Suzuki S, Kojima M, Tokudome S, Mori M, Sakauchi F, Wakai K, et al. Obesity/weight gain and breast cancer risk: findings from the Japan Collaborative Cohort Study for the Evaluation of Cancer Risk. J Epidemiol. 2013;23:139-45.
    • (2013) J. Epidemiol. , vol.23 , pp. 139-145
    • Suzuki, S.1    Kojima, M.2    Tokudome, S.3    Mori, M.4    Sakauchi, F.5    Wakai, K.6
  • 6
    • 77956671253 scopus 로고    scopus 로고
    • Body mass index at the time of diagnosis and the risk of advanced stages and poorly differentiated cancers of the breast: Findings from a case-series study
    • 10.1038/ijo.2010.69 1:STN:280:DC%2BC3cfit1aqsA%3D%3D
    • Stark A, Stahl MS, Kirchner HL, Krum S, Prichard J, Evans J. Body mass index at the time of diagnosis and the risk of advanced stages and poorly differentiated cancers of the breast: findings from a case-series study. Int J Obesity. 2010;34:1381-6.
    • (2010) Int. J. Obesity , vol.34 , pp. 1381-1386
    • Stark, A.1    Stahl, M.S.2    Kirchner, H.L.3    Krum, S.4    Prichard, J.5    Evans, J.6
  • 7
    • 84871339514 scopus 로고    scopus 로고
    • Survival from breast cancer in relation to access to tertiary healthcare, body mass index, tumor characteristics and treatment: A Hellenic Cooperative Oncology Group (HeCOG) study
    • 10.1007/s10654-012-9737-z
    • Panagoupoulou P, Gogas H, Dessypris N, Maniadakdis N, Fountzilas G, Petridou ET. Survival from breast cancer in relation to access to tertiary healthcare, body mass index, tumor characteristics and treatment: a Hellenic Cooperative Oncology Group (HeCOG) study. Eur J Epidemiol. 2012;27:857-66.
    • (2012) Eur. J. Epidemiol. , vol.27 , pp. 857-866
    • Panagoupoulou, P.1    Gogas, H.2    Dessypris, N.3    Maniadakdis, N.4    Fountzilas, G.5    Petridou, E.T.6
  • 8
    • 84869507377 scopus 로고    scopus 로고
    • Obesity at diagnosis is associated with inferior outcomes in hormone-receptor-positive operable breast cancer
    • 22926690 10.1002/cncr.27527 1:CAS:528:DC%2BC38Xhs12itLbO
    • Sparano JA, Wang M, Zhao F, Stearns V, Martino S, Ligibel JA, et al. Obesity at diagnosis is associated with inferior outcomes in hormone-receptor-positive operable breast cancer. Cancer. 2012;118:5937-46.
    • (2012) Cancer , vol.118 , pp. 5937-5946
    • Sparano, J.A.1    Wang, M.2    Zhao, F.3    Stearns, V.4    Martino, S.5    Ligibel, J.A.6
  • 9
    • 79960820132 scopus 로고    scopus 로고
    • The growing challenge of obesity and cancer: An inflammatory issue
    • 10.1111/j.1749-6632.2011.06096.x 1:CAS:528:DC%2BC3MXhtFOqtbfN
    • Harvey AE, Lashinger LM, Hursting SD. The growing challenge of obesity and cancer: an inflammatory issue. Annals N Y Acad Sci. 2011;1229:45-52.
    • (2011) Annals N. Y. Acad. Sci. , vol.1229 , pp. 45-52
    • Harvey, A.E.1    Lashinger, L.M.2    Hursting, S.D.3
  • 10
    • 80053319523 scopus 로고    scopus 로고
    • Pro-inflammatory and tumour proliferative properties of excess visceral adipose tissue
    • 21890265 10.1016/j.canlet.2011.07.034 1:CAS:528:DC%2BC3MXht1GhsLfN
    • Lysaght J, van der Stok EP, Allott EH, Casey R, Donohoe CL, Howard JM, et al. Pro-inflammatory and tumour proliferative properties of excess visceral adipose tissue. Cancer Lett. 2011;312:62-72.
    • (2011) Cancer Lett. , vol.312 , pp. 62-72
    • Lysaght, J.1    Van Der Stok, E.P.2    Allott, E.H.3    Casey, R.4    Donohoe, C.L.5    Howard, J.M.6
  • 11
    • 84864391107 scopus 로고    scopus 로고
    • Adipose tissue and breast epithelial cells: A dangerous dynamic duo in breast cancer
    • 22643115 10.1016/j.canlet.2012.05.019 1:CAS:528:DC%2BC38XoslGktbs%3D
    • Wang Y-Y, Lehuéde C, Laurent V, Dirat B, Dauvillier S, Bochet L, et al. Adipose tissue and breast epithelial cells: a dangerous dynamic duo in breast cancer. Cancer Lett. 2012;324:142-51.
    • (2012) Cancer Lett. , vol.324 , pp. 142-151
    • Wang, Y.-Y.1    Lehuéde, C.2    Laurent, V.3    Dirat, B.4    Dauvillier, S.5    Bochet, L.6
  • 12
    • 47349129465 scopus 로고    scopus 로고
    • Obesity and cancer: Pathophysiological and biological mechanisms
    • 18465361 10.1080/13813450801954303 1:CAS:528:DC%2BD1cXotlKlsL4%3D
    • Renehan AG, Roberts DL, Dive C. Obesity and cancer: pathophysiological and biological mechanisms. Arch Physiol Biochem. 2008;114:71-83.
    • (2008) Arch. Physiol. Biochem. , vol.114 , pp. 71-83
    • Renehan, A.G.1    Roberts, D.L.2    Dive, C.3
  • 13
    • 0033547260 scopus 로고    scopus 로고
    • Physiological consequences of ectopic agouti gene expression: The yellow obese mouse syndrome
    • 11015573 1:CAS:528:DC%2BD3cXlt12isb0%3D
    • Wolff GL, Roberts DW, Mountjoy KG. Physiological consequences of ectopic agouti gene expression: the yellow obese mouse syndrome. Physiol Genomics. 1999;1:151-63.
    • (1999) Physiol. Genomics , vol.1 , pp. 151-163
    • Wolff, G.L.1    Roberts, D.W.2    Mountjoy, K.G.3
  • 14
    • 0037476566 scopus 로고
    • y gene on mammary-gland tumors, hepatomas, and normal growth in mice
    • 13713953 1:STN:280:DyaF3c%2FjtlGjtg%3D%3D
    • y gene on mammary-gland tumors, hepatomas, and normal growth in mice. J Natl Cancer Inst. 1961;26:969-83.
    • (1961) J. Natl. Cancer Inst. , vol.26 , pp. 969-983
    • Heston, W.E.1    Vlahakis, G.2
  • 15
    • 0014293748 scopus 로고
    • vy- a high hepatoma and mammary tumor strain of mice
    • 4298250 1:STN:280:DyaF1czhvVyntg%3D%3D
    • vy- a high hepatoma and mammary tumor strain of mice. J Natl Cancer Inst. 1968;40:1161-6.
    • (1968) J. Natl. Cancer Inst. , vol.40 , pp. 1161-1166
    • Heston, W.E.1    Vlahakis, G.2
  • 16
    • 0018674099 scopus 로고
    • Manifestation of hyperplastic alveolar modules and mammary tumors in "viable yellow" and non-yellow mice
    • 288935 1:STN:280:DyaE1M3kt1Kjug%3D%3D
    • Wolff GL, Medina D, Umholtz RL. Manifestation of hyperplastic alveolar modules and mammary tumors in "viable yellow" and non-yellow mice. J Natl Cancer Inst. 1979;63:781-5.
    • (1979) J. Natl. Cancer Inst. , vol.63 , pp. 781-785
    • Wolff, G.L.1    Medina, D.2    Umholtz, R.L.3
  • 18
    • 0000736325 scopus 로고
    • Obese, a new mutation in the house mouse
    • 1:STN:280:DyaG3M%2FlsVSrtQ%3D%3D
    • Ingalls AM, Dickie MM, Snell GD. Obese, a new mutation in the house mouse. J Heredity. 1950;41:317-8.
    • (1950) J. Heredity , vol.41 , pp. 317-318
    • Ingalls, A.M.1    Dickie, M.M.2    Snell, G.D.3
  • 19
    • 0028139089 scopus 로고
    • Positional cloning of the mouse obese gene and its human homologue
    • 7984236 10.1038/372425a0 1:CAS:528:DyaK2MXisVGqsbs%3D
    • Zhang Y, Proenca R, Maffei M, Barone M, Leopold L, Friedman JM. Positional cloning of the mouse obese gene and its human homologue. Nature. 1994;372:425-32.
    • (1994) Nature , vol.372 , pp. 425-432
    • Zhang, Y.1    Proenca, R.2    Maffei, M.3    Barone, M.4    Leopold, L.5    Friedman, J.M.6
  • 20
    • 0000613070 scopus 로고
    • Genetic obesity and neoplasia
    • 13907025 1:STN:280:DyaF38%2FkvVCjuw%3D%3D
    • Heston WE, Vlahakis G. Genetic obesity and neoplasia. J Natl Cancer Inst. 1962;29:197-209.
    • (1962) J. Natl. Cancer Inst. , vol.29 , pp. 197-209
    • Heston, W.E.1    Vlahakis, G.2
  • 21
    • 0026650727 scopus 로고
    • Distinctive patterns of hyperplasia in transgenic mice with mouse mammary tumor virus transforming growth factor-α. Characterization of mammary gland and skin proliferations
    • 1316084 1:STN:280:DyaK383lsV2gsA%3D%3D
    • Halter SA, Dempsey PJ, Matsui Y, Stokes K, Graves-Deal R, Hogan BLM, et al. Distinctive patterns of hyperplasia in transgenic mice with mouse mammary tumor virus transforming growth factor-α. Characterization of mammary gland and skin proliferations. Am J Pathol. 1992;140:1131-46.
    • (1992) Am. J. Pathol. , vol.140 , pp. 1131-1146
    • Halter, S.A.1    Dempsey, P.J.2    Matsui, Y.3    Stokes, K.4    Graves-Deal, R.5    Hogan, B.L.M.6
  • 23
    • 0028793697 scopus 로고
    • Leptin levels reflect body lipid content in mice: Evidence for diet-induced resistance to leptin action
    • 7489415 10.1038/nm1295-1311 1:CAS:528:DyaK2MXpslGhur8%3D
    • Frederich RC, Hamann A, Anderson S, Lollmann B, Lowell BB, Flier JS. Leptin levels reflect body lipid content in mice: evidence for diet-induced resistance to leptin action. Nat Med. 1995;1:1311-4.
    • (1995) Nat. Med. , vol.1 , pp. 1311-1314
    • Frederich, R.C.1    Hamann, A.2    Anderson, S.3    Lollmann, B.4    Lowell, B.B.5    Flier, J.S.6
  • 25
    • 0037146224 scopus 로고    scopus 로고
    • Leptin- a growth factor for normal and malignant breast cells and normal mammary gland development
    • 12441326 10.1093/jnci/94.22.1704 1:CAS:528:DC%2BD38Xpslequrs%3D
    • Hu X, Juneja SC, Maihle NJ, Cleary MP. Leptin- a growth factor for normal and malignant breast cells and normal mammary gland development. J Natl Cancer Inst. 2002;94:1704-11.
    • (2002) J. Natl. Cancer Inst. , vol.94 , pp. 1704-1711
    • Hu, X.1    Juneja, S.C.2    Maihle, N.J.3    Cleary, M.P.4
  • 27
    • 0037169828 scopus 로고    scopus 로고
    • Identification of leptin receptors in human breast cancer: Functional activity in the T47-D breast cancer cell line
    • 11911959 10.1016/S0303-7207(01)00678-5 1:CAS:528:DC%2BD38XitFWnt7o%3D
    • Laud K, Gourdou I, Pessemesse L, Peyrat JP, Dijane J. Identification of leptin receptors in human breast cancer: functional activity in the T47-D breast cancer cell line. Mol Cell Endocrinol. 2002;188:219-26.
    • (2002) Mol. Cell Endocrinol. , vol.188 , pp. 219-226
    • Laud, K.1    Gourdou, I.2    Pessemesse, L.3    Peyrat, J.P.4    Dijane, J.5
  • 28
    • 0025780434 scopus 로고
    • Reduction of enhanced mammary carcinogenesis in LA/N-cp (corpulent) rats by energy restriction
    • 1901169 10.3181/00379727-196-43202 1:CAS:528:DyaK3MXhvVCiu7w%3D
    • Klurfeld DM, Lloyd LM, Welch CB, Davis MJ, Tulp OL, Kritchevsky D. Reduction of enhanced mammary carcinogenesis in LA/N-cp (corpulent) rats by energy restriction. Proc Soc Exp Biol Med. 1991;196:381-4.
    • (1991) Proc. Soc. Exp. Biol. Med. , vol.196 , pp. 381-384
    • Klurfeld, D.M.1    Lloyd, L.M.2    Welch, C.B.3    Davis, M.J.4    Tulp, O.L.5    Kritchevsky, D.6
  • 29
    • 33644877245 scopus 로고    scopus 로고
    • Obesity promotes 7,12-dimethylbenz(a)anthracene-induced mammary tumor development in female zucker rats
    • 16168107 10.1186/bcr1263 1:CAS:528:DC%2BD2MXls1Gitb4%3D
    • Hakkak R, Holley AW, MacLeod SL, Simpson PM, Fuchs GJ, Jo CH, et al. Obesity promotes 7,12-dimethylbenz(a)anthracene-induced mammary tumor development in female zucker rats. Breast Cancer Res. 2005;7:R627-33.
    • (2005) Breast Cancer Res. , vol.7
    • Hakkak, R.1    Holley, A.W.2    Macleod, S.L.3    Simpson, P.M.4    Fuchs, G.J.5    Jo, C.H.6
  • 30
    • 33947714739 scopus 로고    scopus 로고
    • Obesity increases the incidence of 7,12-dimthylbenz(a)anthracene-induced mammary tumors in an ovariectomized Zucker rat model
    • 17273756 1:CAS:528:DC%2BD2sXjtFGgtrc%3D
    • Hakkak R, MacLeod S, Shaaf S, Holley AW, Simpson P, Fuchs G, et al. Obesity increases the incidence of 7,12-dimthylbenz(a)anthracene-induced mammary tumors in an ovariectomized Zucker rat model. Int J Oncol. 2007;30:557-63.
    • (2007) Int. J. Oncol. , vol.30 , pp. 557-563
    • Hakkak, R.1    Macleod, S.2    Shaaf, S.3    Holley, A.W.4    Simpson, P.5    Fuchs, G.6
  • 31
    • 33645517432 scopus 로고    scopus 로고
    • Excessive weight gain during pregnancy increases carcinogen-induced mammary tumorigenesis in Sprague-Dawley and lean and obese Zucker rats
    • 16549464
    • de Assis S, Wang M, Goel S, Foxworth A, Helferich WG, Hilakivi-Clarke L. Excessive weight gain during pregnancy increases carcinogen-induced mammary tumorigenesis in Sprague-Dawley and lean and obese Zucker rats. J Nutr. 2006;136:998-1004.
    • (2006) J. Nutr. , vol.136 , pp. 998-1004
    • De Assis, S.1    Wang, M.2    Goel, S.3    Foxworth, A.4    Helferich, W.G.5    Hilakivi-Clarke, L.6
  • 32
    • 0035951686 scopus 로고    scopus 로고
    • Susceptibility of lean and obese Zucker rats to tumorigenesis induced by N-methyl-N-nitrosurea
    • 11146220 10.1016/S0304-3835(00)00635-2 1:CAS:528:DC%2BD3MXotVWh
    • Lee WM, Lu S, Medline A, Archer MC. Susceptibility of lean and obese Zucker rats to tumorigenesis induced by N-methyl-N-nitrosurea. Cancer Lett. 2001;162:155-60.
    • (2001) Cancer Lett. , vol.162 , pp. 155-160
    • Lee, W.M.1    Lu, S.2    Medline, A.3    Archer, M.C.4
  • 33
    • 0025133166 scopus 로고
    • Analysis of dietary fat, calories, body weight, and the development of mammary tumors in rats and mice: A review
    • 2203521 1:CAS:528:DyaK3cXmtFSmsbk%3D
    • Freedman LS, Clifford C, Messina M. Analysis of dietary fat, calories, body weight, and the development of mammary tumors in rats and mice: a review. Cancer Res. 1990;50:5710-9.
    • (1990) Cancer Res. , vol.50 , pp. 5710-5719
    • Freedman, L.S.1    Clifford, C.2    Messina, M.3
  • 34
    • 0023227110 scopus 로고
    • Total calories, body weight, and tumor incidence in mice
    • 3828987 1:STN:280:DyaL2s7lvFamtQ%3D%3D
    • Albanes D. Total calories, body weight, and tumor incidence in mice. Cancer Res. 1987;47:1987-92.
    • (1987) Cancer Res. , vol.47 , pp. 1987-1992
    • Albanes, D.1
  • 35
    • 0026583808 scopus 로고
    • Relationship between dietary fat and experimental mammary tumorigenesis: A review and critique
    • 1544139 1:CAS:528:DyaK38XhvFaqurk%3D
    • Welsch CW. Relationship between dietary fat and experimental mammary tumorigenesis: a review and critique. Cancer Res. 1992;52:2040s-8s.
    • (1992) Cancer Res. , vol.52
    • Welsch, C.W.1
  • 36
    • 0028015901 scopus 로고
    • Interrelationship between dietary lipids and calories and experimental mammary gland tumorigenesis
    • 8039139 10.1002/1097-0142(19940801)74:3+<1055: AID- CNCR2820741513>3.0.CO;2-0 1:CAS:528:DyaK2MXnslWmtw%3D%3D
    • Welsch CW. Interrelationship between dietary lipids and calories and experimental mammary gland tumorigenesis. Cancer. 1994;74:1055-62.
    • (1994) Cancer , vol.74 , pp. 1055-1062
    • Welsch, C.W.1
  • 37
    • 0023210951 scopus 로고
    • Fat, calories, and mammary carcinogenesis: Net energy effects
    • 3799517 1:STN:280:DyaL2s%2FpslSruw%3D%3D
    • Pariza MW. Fat, calories, and mammary carcinogenesis: net energy effects. Am J Clin Nutr. 1987;45:261-3.
    • (1987) Am. J. Clin. Nutr. , vol.45 , pp. 261-263
    • Pariza, M.W.1
  • 38
    • 3242887042 scopus 로고    scopus 로고
    • Effect of a high fat diet on body weight and mammary tumor latency in MMTV-TGF-α mice
    • 10.1038/sj.ijo.0802664 1:CAS:528:DC%2BD2cXls1eqtr8%3D
    • Cleary MP, Grande JP, Maihle NJ. Effect of a high fat diet on body weight and mammary tumor latency in MMTV-TGF-α mice. Int J Obesity. 2004;28:956-62.
    • (2004) Int. J. Obesity , vol.28 , pp. 956-962
    • Cleary, M.P.1    Grande, J.P.2    Maihle, N.J.3
  • 39
    • 12744274885 scopus 로고    scopus 로고
    • Effect of dietary-induced obesity and mammary tumor development in MMTV-neu female mice
    • 15623464 10.1207/s15327914nc5002-7
    • Cleary MP, Grande JP, Juneja SC, Maihle NJ. Effect of dietary-induced obesity and mammary tumor development in MMTV-neu female mice. Nutr Cancer. 2004;50:174-80.
    • (2004) Nutr. Cancer , vol.50 , pp. 174-180
    • Cleary, M.P.1    Grande, J.P.2    Juneja, S.C.3    Maihle, N.J.4
  • 40
    • 40349108630 scopus 로고    scopus 로고
    • Effects of high fat diet and/or body weight on mammary tumor leptin and apoptosis signaling pathways in MMTV-TGF-α mice
    • 18162139 10.1186/bcr1840
    • Dogan S, Hu X, Zhang Y, Maihle NJ, Grande JP, Cleary MP. Effects of high fat diet and/or body weight on mammary tumor leptin and apoptosis signaling pathways in MMTV-TGF-α mice. Breast Cancer Res. 2007;9:R91.
    • (2007) Breast Cancer Res. , vol.9 , pp. 91
    • Dogan, S.1    Hu, X.2    Zhang, Y.3    Maihle, N.J.4    Grande, J.P.5    Cleary, M.P.6
  • 41
    • 77955551255 scopus 로고    scopus 로고
    • Evidence for tumor promoting effect of high-fat diet independent of insulin resistance in HER2/Neu mammary carcinogenesis
    • 19851863 10.1007/s10549-009-0586-8 1:CAS:528:DC%2BC3cXoslehsrg%3D
    • Khalid S, Hwang D, Babichev Y, Kolli R, Altamentova S, Koren S, et al. Evidence for tumor promoting effect of high-fat diet independent of insulin resistance in HER2/Neu mammary carcinogenesis. Breast Cancer Res Treat. 2010;122:647-65.
    • (2010) Breast Cancer Res. Treat. , vol.122 , pp. 647-665
    • Khalid, S.1    Hwang, D.2    Babichev, Y.3    Kolli, R.4    Altamentova, S.5    Koren, S.6
  • 42
    • 77950188357 scopus 로고    scopus 로고
    • A surprising link between the energetics of ovariectomy-induced weight gain and mammary tumor progression in obese rats
    • 19798068 10.1038/oby.2009.307
    • MacLean PS, Giles ED, Johnson GC, McDaniel SM, Fleming-Elder BK, Gilman KA, et al. A surprising link between the energetics of ovariectomy-induced weight gain and mammary tumor progression in obese rats. Obesity. 2010;18:696-703.
    • (2010) Obesity , vol.18 , pp. 696-703
    • Maclean, P.S.1    Giles, E.D.2    Johnson, G.C.3    McDaniel, S.M.4    Fleming-Elder, B.K.5    Gilman, K.A.6
  • 43
    • 84871252548 scopus 로고    scopus 로고
    • Obesity and overfeeding affecting both tumor and systemic metabolism activates the progesterone receptor to contribute to postmenopausal breast cancer
    • 23222299 10.1158/0008-5472.CAN-12-1653 1:CAS:528:DC%2BC38XhvVyns7jN
    • Giles ED, Wellberg EA, Astling DP, Anderson SM, Thor AD, Jindal S, et al. Obesity and overfeeding affecting both tumor and systemic metabolism activates the progesterone receptor to contribute to postmenopausal breast cancer. Cancer Res. 2012;72:6490-501.
    • (2012) Cancer Res. , vol.72 , pp. 6490-6501
    • Giles, E.D.1    Wellberg, E.A.2    Astling, D.P.3    Anderson, S.M.4    Thor, A.D.5    Jindal, S.6
  • 44
    • 0030774390 scopus 로고    scopus 로고
    • Selective breeding for diet-induced obesity and resistance in Sprague-Dawley rats
    • 9277561 1:CAS:528:DyaK2sXls12nurs%3D
    • Levin BE, Dunn-Meynell AA, Balkan B, Keesey RE. Selective breeding for diet-induced obesity and resistance in Sprague-Dawley rats. Am J Physiol. 1997;273:R725-30.
    • (1997) Am. J. Physiol. , vol.273
    • Levin, B.E.1    Dunn-Meynell, A.A.2    Balkan, B.3    Keesey, R.E.4
  • 45
    • 77955612057 scopus 로고    scopus 로고
    • Long-term characterization of diet-induced obese and diet-resistant rat model: A polygenetic rat model mimicking the human obesity syndrome
    • 20508079 10.1677/JOE-10-0004 1:CAS:528:DC%2BC3cXhtFensLvO
    • Madsen AN, Hansen G, Paulsen SJ, Lykkegaard K, Madsen AN, Hansen G, et al. Long-term characterization of diet-induced obese and diet-resistant rat model: a polygenetic rat model mimicking the human obesity syndrome. JEndocrinol. 2010;206:287-96.
    • (2010) J.Endocrinol , vol.206 , pp. 287-296
    • Madsen, A.N.1    Hansen, G.2    Paulsen, S.J.3    Lykkegaard, K.4    Madsen, A.N.5    Hansen, G.6
  • 46
    • 0041919296 scopus 로고    scopus 로고
    • Ontology of diet-induced obesity in selectively bred Sprague-Dawley rats
    • Ricci MR, Levin BE. Ontology of diet-induced obesity in selectively bred Sprague-Dawley rats. Am J Physiol. 2003;285:R610-8.
    • (2003) Am. J. Physiol. , vol.285
    • Ricci, M.R.1    Levin, B.E.2
  • 47
    • 75749136091 scopus 로고    scopus 로고
    • Characterization of β-cell mass and insulin resistance in diet-induced obese and diet-resistant rats
    • 19661956 10.1038/oby.2009.245 1:CAS:528:DC%2BC3cXht1KksL8%3D
    • Paulsen SJ, Jelsing J, Madsen AN, Hansen G, Lykkegaard K, Larsen LK, et al. Characterization of β-cell mass and insulin resistance in diet-induced obese and diet-resistant rats. Obesity. 2010;18:266-73.
    • (2010) Obesity , vol.18 , pp. 266-273
    • Paulsen, S.J.1    Jelsing, J.2    Madsen, A.N.3    Hansen, G.4    Lykkegaard, K.5    Larsen, L.K.6
  • 48
    • 0028785824 scopus 로고
    • Rapid induction of mammary intraductal proliferations, ductal carcinoma in situ and carcinomas by the injection of sexually immature female rats with 1-methyl-1-nitrosourea
    • 7586143 10.1093/carcin/16.10.2407 1:CAS:528:DyaK2MXovFyku74%3D
    • Thompson HJ, McGinley JN, Rothhammer K, Singh M. Rapid induction of mammary intraductal proliferations, ductal carcinoma in situ and carcinomas by the injection of sexually immature female rats with 1-methyl-1-nitrosourea. Carcinogenesis. 1995;16:2407-11.
    • (1995) Carcinogenesis , vol.16 , pp. 2407-2411
    • Thompson, H.J.1    McGinley, J.N.2    Rothhammer, K.3    Singh, M.4
  • 49
    • 0031594617 scopus 로고    scopus 로고
    • Pathogenetic characterization of 1-methyl-1-nitrosourea-induced mammary carcinomas in the rat
    • 9472716 10.1093/carcin/19.1.223 1:CAS:528:DyaK1cXpsVCltg%3D%3D
    • Lu J, Jiang C, Mitrenga T, Cutter G, Thompson HJ. Pathogenetic characterization of 1-methyl-1-nitrosourea-induced mammary carcinomas in the rat. Carcinogenesis. 1998;19:223-7.
    • (1998) Carcinogenesis , vol.19 , pp. 223-227
    • Lu, J.1    Jiang, C.2    Mitrenga, T.3    Cutter, G.4    Thompson, H.J.5
  • 50
    • 0034048976 scopus 로고    scopus 로고
    • A comparison of the histopathology of premalignant and malignant mammary gland lesions induced in sexually immature rats with those occurring the human
    • 10701691 10.1038/labinvest.3780025 1:STN:280:DC%2BD3c7mtlKhtA%3D%3D
    • Singh M, McGinley JN, Thompson HJ. A comparison of the histopathology of premalignant and malignant mammary gland lesions induced in sexually immature rats with those occurring the human. Lab Invest. 2000;80:221-31.
    • (2000) Lab. Invest. , vol.80 , pp. 221-231
    • Singh, M.1    McGinley, J.N.2    Thompson, H.J.3
  • 51
    • 84890081714 scopus 로고    scopus 로고
    • Excess weight gain accelerates carcinogenesis in pemenopausal breast cancer model
    • (in press)
    • Matthews SB, Zhu Z, Jiang W, McGinley J, Thompson HJ. Excess weight gain accelerates carcinogenesis in pemenopausal breast cancer model. Cancer Prev Res. 2013; (in press).
    • (2013) Cancer Prev Res
    • Matthews, S.B.1    Zhu, Z.2    Jiang, W.3    McGinley, J.4    Thompson, H.J.5
  • 52
    • 70449635843 scopus 로고    scopus 로고
    • Obesity and the associated mediators leptin, estrogen and IGF-I enhance proliferation and early tumorigenesis of breast cancer cells
    • 19838920 10.1080/01635580802610115 1:CAS:528:DC%2BD1MXhtVGrtbbE
    • Lautenbach A, Budde A, Wrann CD, Teichmann B, Vieten G, Karl T, et al. Obesity and the associated mediators leptin, estrogen and IGF-I enhance proliferation and early tumorigenesis of breast cancer cells. Nutr Cancer. 2009;61:484-91.
    • (2009) Nutr. Cancer , vol.61 , pp. 484-491
    • Lautenbach, A.1    Budde, A.2    Wrann, C.D.3    Teichmann, B.4    Vieten, G.5    Karl, T.6
  • 53
    • 0031766722 scopus 로고    scopus 로고
    • Hyperphagia and weight gain after gold-thioglucose: Relation to hypothalamic neuropeptide y and propiomelanocortin
    • 9794456 10.1210/en.139.11.4483 1:CAS:528:DyaK1cXntFWltrY%3D
    • Bergen HT, Mizuno TM, Taylor J, Mobbs CV. Hyperphagia and weight gain after gold-thioglucose: relation to hypothalamic neuropeptide Y and propiomelanocortin. Endocrinology. 1998;139:4483-8.
    • (1998) Endocrinology , vol.139 , pp. 4483-4488
    • Bergen, H.T.1    Mizuno, T.M.2    Taylor, J.3    Mobbs, C.V.4
  • 54
    • 0042540940 scopus 로고
    • Obesity and food requirements in albino mice following administration of gold thioglucose
    • 15432717 1:CAS:528:DyaG3cXlslWisA%3D%3D
    • Waxler SH, Brecher G. Obesity and food requirements in albino mice following administration of gold thioglucose. Am J Physiol. 1950;162:428-33.
    • (1950) Am. J. Physiol. , vol.162 , pp. 428-433
    • Waxler, S.H.1    Brecher, G.2
  • 55
    • 0036100581 scopus 로고    scopus 로고
    • Dietary modulation of cirulating leptin levels: Site-specific changes in fat deposition and Ob mRNA expression
    • 11987025 10.1055/s-2002-26707 1:CAS:528:DC%2BD38Xkt1entLY%3D
    • Walker CG, Bryson JM, Phuyal JL, Caterson ID. Dietary modulation of cirulating leptin levels: site-specific changes in fat deposition and Ob mRNA expression. Horm Metab Res. 2002;34:176-81.
    • (2002) Horm. Metab. Res. , vol.34 , pp. 176-181
    • Walker, C.G.1    Bryson, J.M.2    Phuyal, J.L.3    Caterson, I.D.4
  • 56
    • 0032748597 scopus 로고    scopus 로고
    • 22-5β = taurocholenic acid on hepatic cholesterol fatty acid in goldthioglucose obese mice fed low- or high-fat diets
    • 22-5β = taurocholenic acid on hepatic cholesterol fatty acid in goldthioglucose obese mice fed low- or high-fat diets. J Nutr Biochem. 1999;10:638-43.
    • (1999) J Nutr Biochem , vol.10 , pp. 638-643
    • Jansen, G.R.1
  • 57
    • 0023929610 scopus 로고
    • Effects of litter size and subsequent gold-thioglucose-induced obesity on adipose tissue weight, distribution and cellularity in male and female mice: An age study
    • 3134938 10.1079/BJN19880061 1:CAS:528:DyaL1cXktVGls70%3D
    • Roberts JL, Whittington FM, Enser M. Effects of litter size and subsequent gold-thioglucose-induced obesity on adipose tissue weight, distribution and cellularity in male and female mice: an age study. Brit J Nutr. 1988;59:519-33.
    • (1988) Brit. J. Nutr. , vol.59 , pp. 519-533
    • Roberts, J.L.1    Whittington, F.M.2    Enser, M.3
  • 58
    • 0001540069 scopus 로고
    • Obesity and the time of appearance of spontaneous mammary carcinoma in C3H mice
    • 13042818 1:CAS:528:DyaG3sXlt1eqtw%3D%3D
    • Waxler SH, Tabar P, Melcher LP. Obesity and the time of appearance of spontaneous mammary carcinoma in C3H mice. Cancer Res. 1953;13:276-8.
    • (1953) Cancer Res. , vol.13 , pp. 276-278
    • Waxler, S.H.1    Tabar, P.2    Melcher, L.P.3
  • 59
    • 0013908917 scopus 로고
    • Augmentation of mammary tumors in castrated obese C3H mice
    • 5934796 1:STN:280:DyaF287jsVynuw%3D%3D
    • Waxler SH, Leef MF. Augmentation of mammary tumors in castrated obese C3H mice. Cancer Res. 1966;26:860-2.
    • (1966) Cancer Res. , vol.26 , pp. 860-862
    • Waxler, S.H.1    Leef, M.F.2
  • 60
    • 58849105532 scopus 로고    scopus 로고
    • Mammary tumor development from T47D human breast cancer cells in obese ovariectomized mice with and without estradiol supplements
    • 18392696 10.1007/s10549-008-9991-7 1:CAS:528:DC%2BD1MXhtVehsLs%3D
    • Nkhata KJ, Ray A, Dogan S, Grande JP, Cleary MP. Mammary tumor development from T47D human breast cancer cells in obese ovariectomized mice with and without estradiol supplements. Breast Cancer Res Treat. 2009;114:71-83.
    • (2009) Breast Cancer Res. Treat. , vol.114 , pp. 71-83
    • Nkhata, K.J.1    Ray, A.2    Dogan, S.3    Grande, J.P.4    Cleary, M.P.5
  • 61
    • 34347355253 scopus 로고    scopus 로고
    • Diet-induced obesity and mammary tumor development in relation to estrogen receptor status
    • 17399892 10.1016/j.canlet.2007.02.005 1:CAS:528:DC%2BD2sXnsFKqsLY%3D
    • Ray A, Nkhata KJ, Grande JP, Cleary MP. Diet-induced obesity and mammary tumor development in relation to estrogen receptor status. Cancer Letters. 2007;253:291-300.
    • (2007) Cancer Letters , vol.253 , pp. 291-300
    • Ray, A.1    Nkhata, K.J.2    Grande, J.P.3    Cleary, M.P.4
  • 62
    • 34347355253 scopus 로고    scopus 로고
    • Diet-induced obesity and mammary tumor development in relation to estrogen receptor status
    • 17399892 10.1016/j.canlet.2007.02.005 1:CAS:528:DC%2BD2sXnsFKqsLY%3D
    • Ray A, Nkhata K, Grande JP, Cleary MP. Diet-induced obesity and mammary tumor development in relation to estrogen receptor status. Cancer Lett. 2007;253:291-300.
    • (2007) Cancer Lett. , vol.253 , pp. 291-300
    • Ray, A.1    Nkhata, K.2    Grande, J.P.3    Cleary, M.P.4
  • 63
    • 80054817965 scopus 로고    scopus 로고
    • Estrogen inhibits the effects of obesity and alcohol on mammary tumors and fatty liver
    • 21850368 1:CAS:528:DC%2BC3MXhs1SlsLfM
    • Hong J, Holcomb VB, Kushiro K, Nunez NP. Estrogen inhibits the effects of obesity and alcohol on mammary tumors and fatty liver. Int J Oncol. 2011;39:1443-53.
    • (2011) Int. J. Oncol. , vol.39 , pp. 1443-1453
    • Hong, J.1    Holcomb, V.B.2    Kushiro, K.3    Nunez, N.P.4
  • 65
    • 84876438500 scopus 로고    scopus 로고
    • The enhancing effects of obesity on mammary tumor growth and Akt/mTor pathway activation persist after weight loss and are reversed by RAD001
    • 22290600 10.1002/mc.21878
    • De Angel RE, Conti CJ, Wheatley KE, Brenner AJ, Otto G, DeGraffenried LA, et al. The enhancing effects of obesity on mammary tumor growth and Akt/mTor pathway activation persist after weight loss and are reversed by RAD001. Mol Carcinog. 2013;52:446-58.
    • (2013) Mol. Carcinog. , vol.52 , pp. 446-458
    • De Angel, R.E.1    Conti, C.J.2    Wheatley, K.E.3    Brenner, A.J.4    Otto, G.5    Degraffenried, L.A.6
  • 66
    • 79957533706 scopus 로고    scopus 로고
    • Postmenopausal obesity promotes tumor angiogenesis and breast cancer progression in mice
    • 21451264 10.4161/cbt.11.10.15473 1:CAS:528:DC%2BC38XnsValuw%3D%3D
    • Gu J-W, Young E, Patterson SG, Makey KL, Wells J, Huang M, et al. Postmenopausal obesity promotes tumor angiogenesis and breast cancer progression in mice. Cancer Biol Ther. 2011;11:910-7.
    • (2011) Cancer Biol. Ther. , vol.11 , pp. 910-917
    • Gu, J.-W.1    Young, E.2    Patterson, S.G.3    Makey, K.L.4    Wells, J.5    Huang, M.6
  • 67
    • 80052155796 scopus 로고    scopus 로고
    • Leptin deficiency suppresses MMTV-Wnt-1 mammary tumor growth in obese mice and abrogates tumor initiating cell survival
    • 21636700 10.1530/ERC-11-0102 1:CAS:528:DC%2BC3MXhtlShsbzK
    • Zheng Q, Dunlap SM, Zhu J, Downs-Kelly E, Rich J, Hursting SD, et al. Leptin deficiency suppresses MMTV-Wnt-1 mammary tumor growth in obese mice and abrogates tumor initiating cell survival. Endocrine-Related Cancer. 2011;18:491-503.
    • (2011) Endocrine-Related Cancer , vol.18 , pp. 491-503
    • Zheng, Q.1    Dunlap, S.M.2    Zhu, J.3    Downs-Kelly, E.4    Rich, J.5    Hursting, S.D.6
  • 68
    • 0031125661 scopus 로고    scopus 로고
    • Aromatase in the normal breast and breast cancer
    • 9365202 10.1016/S0960-0760(97)80024-6 1:CAS:528:DyaK2sXnt1Cqtr4%3D
    • Brodie A, Lu Q, Nakamura J. Aromatase in the normal breast and breast cancer. J Steroid Biochem Molec Biol. 1997;61:281-6.
    • (1997) J. Steroid Biochem. Molec. Biol. , vol.61 , pp. 281-286
    • Brodie, A.1    Lu, Q.2    Nakamura, J.3
  • 69
    • 0023210536 scopus 로고
    • Adipose tissue as a source of hormones
    • 3541569 1:CAS:528:DyaL2sXhtFels7k%3D
    • Siiteri PK. Adipose tissue as a source of hormones. Am J Clin Nutr. 1987;45:277-82.
    • (1987) Am. J. Clin. Nutr. , vol.45 , pp. 277-282
    • Siiteri, P.K.1
  • 70
    • 79955862214 scopus 로고    scopus 로고
    • Obesity is associated with inflammation and elevated aromatase expression in the mouse mammary gland
    • 10.1158/1940-6207.CAPR-10-0381 1:CAS:528:DC%2BC3MXktl2ltb0%3D
    • Subbaramaiah K, Howe LR, Bhardwaj P, Du B, Gravaghi C, Yantiss RK, et al. Obesity is associated with inflammation and elevated aromatase expression in the mouse mammary gland. Cancer Prev Res. 2011;4:329-46.
    • (2011) Cancer Prev. Res. , vol.4 , pp. 329-346
    • Subbaramaiah, K.1    Howe, L.R.2    Bhardwaj, P.3    Du, B.4    Gravaghi, C.5    Yantiss, R.K.6
  • 71
    • 77956702041 scopus 로고    scopus 로고
    • Pubertal exposure to high fat diet causes mouse strain-dependent alterations in mammary gland development and estrogen responsiveness
    • 10.1038/ijo.2010.51 1:CAS:528:DC%2BC3cXhtFChtL3K
    • Olson LK, Tan Y, Zhao Y, Aupperlee MD, Haslam SZ. Pubertal exposure to high fat diet causes mouse strain-dependent alterations in mammary gland development and estrogen responsiveness. Int J Obesity. 2010;34:1415-56.
    • (2010) Int. J. Obesity , vol.34 , pp. 1415-1456
    • Olson, L.K.1    Tan, Y.2    Zhao, Y.3    Aupperlee, M.D.4    Haslam, S.Z.5
  • 72
    • 66149086187 scopus 로고    scopus 로고
    • Diet-induced obesity disrupts ductal development in the mammary glands of nonpregnanct mice
    • 10.1002/dvdy.21947 1:CAS:528:DC%2BD1MXmtV2jtb4%3D
    • Kamikawa A, Ichii O, Yamaji D, Imao T, Suzuki C, Okamatsu-Ogura Y, et al. Diet-induced obesity disrupts ductal development in the mammary glands of nonpregnanct mice. Dev Dynamics. 2009;238:1092-9.
    • (2009) Dev. Dynamics , vol.238 , pp. 1092-1099
    • Kamikawa, A.1    Ichii, O.2    Yamaji, D.3    Imao, T.4    Suzuki, C.5    Okamatsu-Ogura, Y.6
  • 73
    • 0025903895 scopus 로고
    • Body conformation, diet, and risk of breast cancer in pet dogs: A case-control study
    • 2018024 1:STN:280:DyaK3M3gs1ersg%3D%3D
    • Sonnenschein EG, Glickman LT, Goldschmidt LT, McKee LJ. Body conformation, diet, and risk of breast cancer in pet dogs: a case-control study. Am J Epidemiol. 1991;133:694-703.
    • (1991) Am. J. Epidemiol. , vol.133 , pp. 694-703
    • Sonnenschein, E.G.1    Glickman, L.T.2    Goldschmidt, L.T.3    McKee, L.J.4
  • 74
    • 0032063386 scopus 로고    scopus 로고
    • Relation between habitual diet and canine mammary tumors in a case-control study
    • 10.1111/j.1939-1676.1998.tb02108.x
    • Alenza DP, Rutterman GR, Peña L, Beynen AC, Cuesta P. Relation between habitual diet and canine mammary tumors in a case-control study. J Vet Intern Med. 1998;12:132-9.
    • (1998) J. Vet. Intern. Med , vol.12 , pp. 132-139
    • Alenza, D.P.1    Rutterman, G.R.2    Peña, L.3    Beynen, A.C.4    Cuesta, P.5
  • 76
    • 82555201367 scopus 로고    scopus 로고
    • Adipocyte is a non-trivial, dynamic partner of breast cancer cells
    • 21948738 10.1387/ijdb.113365jt
    • Tan J, Buache E, Chenard M-P, Dali-Youcef N, Rio M-C. Adipocyte is a non-trivial, dynamic partner of breast cancer cells. Int J Dev Biol. 2011;55:851-9.
    • (2011) Int. J. Dev. Biol. , vol.55 , pp. 851-859
    • Tan, J.1    Buache, E.2    Chenard, M.-P.3    Dali-Youcef, N.4    Rio, M.-C.5
  • 77
    • 34547741589 scopus 로고    scopus 로고
    • Adipokines as endocrine, paracrine, and autocrine factors in breast cancer risk and progression
    • 17639037 10.1677/ERC-06-0068 1:CAS:528:DC%2BD2sXhtV2lsr%2FE
    • Vona-Davis L, Rose DP. Adipokines as endocrine, paracrine, and autocrine factors in breast cancer risk and progression. Endocrine-Related Cancer. 2007;14:189-206.
    • (2007) Endocrine-Related Cancer , vol.14 , pp. 189-206
    • Vona-Davis, L.1    Rose, D.P.2
  • 78
    • 84875227258 scopus 로고    scopus 로고
    • Adipocytes: Impact on tumor growth and potential sites for therapeutic intervention
    • 10.1016/j.pharmthera.2013.01.008 1:CAS:528:DC%2BC3sXitlaqsbs%3D
    • Hefetz-Sela S, Scherer PE. Adipocytes: impact on tumor growth and potential sites for therapeutic intervention. Pharmac Ther. 2013;138:197-210.
    • (2013) Pharmac. Ther. , vol.138 , pp. 197-210
    • Hefetz-Sela, S.1    Scherer, P.E.2
  • 79
    • 84885409872 scopus 로고    scopus 로고
    • Local adipocytes enable estrogen-dependent breast cancer growth. Role of leptin and aromatase
    • 10.4161/adip.23645 1:CAS:528:DC%2BC3sXisVersLY%3D
    • Liu E, Samad F, Mueller BM. Local adipocytes enable estrogen-dependent breast cancer growth. Role of leptin and aromatase. Adipocyte. 2013;2:1-5.
    • (2013) Adipocyte , vol.2 , pp. 1-5
    • Liu, E.1    Samad, F.2    Mueller, B.M.3


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