Mice generated by in vitro fertilization exhibit vascular dysfunction and shortened life span

Journal of Clinical Investigation

Volumn 123, Issue 12, 2013, Pages 5052-5060

  Rexhaj, Emrush ^a   Paoloni Giacobino, Ariane ^b   Rimoldi, Stefano F ^a   Fuster, Daniel G ^c   Anderegg, Manuel ^c   Somm, Emmanuel ^a   Bouillet, Elisa ^d   Allemann, Yves ^a   Sartori, Claudio ^a,e   Scherrer, Urs ^a,f  

^a BERN UNIVERSITY HOSPITAL   (Switzerland)

^b GENEVA UNIVERSITY HOSPITALS   (Switzerland)

^c UNIVERSITY OF BERN   (Switzerland)

^d UNIVERSITY OF GENEVA MEDICAL SCHOOL   (Switzerland)

^e LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

^f UNIVERSIDAD DE TARAPACÁ   (Chile)

Author keywords

[No Author keywords available]

Indexed keywords

BUTYRIC ACID; DIPEPTIDYL CARBOXYPEPTIDASE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; ENDOTHELIN 1; MESSENGER RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERIAL PRESSURE; ARTERIAL STIFFNESS; ARTICLE; BLASTOCYST; CONTROLLED STUDY; DNA METHYLATION; DNA MODIFICATION; EMBRYO TRANSFER; ENDOTHELIAL DYSFUNCTION; EPIGENETICS; FEMALE; FERTILIZATION IN VITRO; GENOME IMPRINTING; HUMAN; HUMAN CELL; HYPERTENSION; IN VIVO STUDY; INFERTILITY THERAPY; LIFESPAN; LIPID DIET; MALE; MESENTERIC ARTERY; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OVULATION; PRIORITY JOURNAL; PROGENY; PROMOTER REGION; PROTEIN EXPRESSION; VASCULAR DISEASE; VASCULARIZATION;

ANIMALS; AORTA; BUTYRATES; CARDIOVASCULAR ABNORMALITIES; DIET, ATHEROGENIC; DISEASE SUSCEPTIBILITY; DNA METHYLATION; DOWN-REGULATION; ENDOTHELIUM, VASCULAR; FEMALE; FERTILIZATION IN VITRO; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HISTONE DEACETYLASE INHIBITORS; HYPERTENSION; LONGEVITY; MALE; MICE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE III; OVULATION INDUCTION; PROMOTER REGIONS, GENETIC; VASCULAR RESISTANCE; VASODILATION;

EID: 84890011316     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI68943     Document Type: Article

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