-
1
-
-
17444409344
-
Epigenetic reprogramming in mammals
-
Spec No 1
-
Morgan H.D., Santos F., Green K., Dean W., and Reik W. Epigenetic reprogramming in mammals. Hum Mol Genet 14 (2005) R47-R58 Spec No 1
-
(2005)
Hum Mol Genet
, vol.14
-
-
Morgan, H.D.1
Santos, F.2
Green, K.3
Dean, W.4
Reik, W.5
-
2
-
-
38349100549
-
Epigenetic events in mammalian germ-cell development: reprogramming and beyond
-
Sasaki H., and Matsui Y. Epigenetic events in mammalian germ-cell development: reprogramming and beyond. Nat Rev Genet 2008 (2008) 129-140
-
(2008)
Nat Rev Genet
, vol.2008
, pp. 129-140
-
-
Sasaki, H.1
Matsui, Y.2
-
3
-
-
0021237658
-
Development of reconstituted mouse eggs suggests imprinting of the genome during gametogenesis
-
Surani M.A., Barton S.C., and Norris M.L. Development of reconstituted mouse eggs suggests imprinting of the genome during gametogenesis. Nature 308 (1984) 548-550
-
(1984)
Nature
, vol.308
, pp. 548-550
-
-
Surani, M.A.1
Barton, S.C.2
Norris, M.L.3
-
4
-
-
0021740225
-
Inability of mouse blastomere nuclei transferred to enucleated zygotes to support development in vitro
-
McGrath J., and Solter D. Inability of mouse blastomere nuclei transferred to enucleated zygotes to support development in vitro. Science 226 (1984) 1317-1319
-
(1984)
Science
, vol.226
, pp. 1317-1319
-
-
McGrath, J.1
Solter, D.2
-
5
-
-
0023220910
-
Degree of methylation of transgenes is dependent on gamete of origin
-
Sapienza C., Peterson A.C., Rossant J., and Balling R. Degree of methylation of transgenes is dependent on gamete of origin. Nature 328 (1987) 251-254
-
(1987)
Nature
, vol.328
, pp. 251-254
-
-
Sapienza, C.1
Peterson, A.C.2
Rossant, J.3
Balling, R.4
-
8
-
-
0023274924
-
Maternal inhibition of hepatitis B surface antigen gene expression in transgenic mice correlates with de novo methylation
-
Hadchouel M., Farza H., Simon D., Tiollais P., and Pourcel C. Maternal inhibition of hepatitis B surface antigen gene expression in transgenic mice correlates with de novo methylation. Nature 329 (1987) 454-456
-
(1987)
Nature
, vol.329
, pp. 454-456
-
-
Hadchouel, M.1
Farza, H.2
Simon, D.3
Tiollais, P.4
Pourcel, C.5
-
9
-
-
0029587022
-
Gametic imprinting in mammals
-
Barlow D.P. Gametic imprinting in mammals. Science 270 (1995) 1610-1613
-
(1995)
Science
, vol.270
, pp. 1610-1613
-
-
Barlow, D.P.1
-
10
-
-
33947310031
-
Environmental epigenomics and disease susceptibility
-
Jirtle R.L., and Skinner M.K. Environmental epigenomics and disease susceptibility. Nat Rev Genet 8 (2007) 253-262
-
(2007)
Nat Rev Genet
, vol.8
, pp. 253-262
-
-
Jirtle, R.L.1
Skinner, M.K.2
-
11
-
-
0023279926
-
The inheritance of epigenetic defects
-
Holliday R. The inheritance of epigenetic defects. Science 238 (1987) 163-170
-
(1987)
Science
, vol.238
, pp. 163-170
-
-
Holliday, R.1
-
12
-
-
0347991998
-
Age-associated activation of epigenetically repressed genes in the mouse
-
Bennett-Baker P.E., Wilkowski J., and Burke D.T. Age-associated activation of epigenetically repressed genes in the mouse. Genetics 165 (2003) 2055-2062
-
(2003)
Genetics
, vol.165
, pp. 2055-2062
-
-
Bennett-Baker, P.E.1
Wilkowski, J.2
Burke, D.T.3
-
13
-
-
0037371674
-
Epimutations in Prader-Willi and Angelman syndromes: a molecular study of 136 patients with an imprinting defect
-
Buiting K., Gross S., Lich C., Gillessen-Kaesbach G., el-Maarri O., and Horsthemke B. Epimutations in Prader-Willi and Angelman syndromes: a molecular study of 136 patients with an imprinting defect. Am J Hum Genet 72 (2003) 571-577
-
(2003)
Am J Hum Genet
, vol.72
, pp. 571-577
-
-
Buiting, K.1
Gross, S.2
Lich, C.3
Gillessen-Kaesbach, G.4
el-Maarri, O.5
Horsthemke, B.6
-
14
-
-
2442424419
-
Germline epimutation of MLH1 in individuals with multiple cancers
-
Suter C.M., Martin D.I., and Ward R.L. Germline epimutation of MLH1 in individuals with multiple cancers. Nat Genet 36 (2004) 497-501
-
(2004)
Nat Genet
, vol.36
, pp. 497-501
-
-
Suter, C.M.1
Martin, D.I.2
Ward, R.L.3
-
15
-
-
25144454048
-
Epimutation of the telomeric imprinting center region on chromosome 11p15 in Silver-Russell syndrome
-
Gicquel C., Rossignol S., Cabrol S., Houang M., Steunou V., Barbu V., Danton F., Thibaud N., Le Merrer M., Burglen L., et al. Epimutation of the telomeric imprinting center region on chromosome 11p15 in Silver-Russell syndrome. Nat Genet 37 (2005) 1003-1007
-
(2005)
Nat Genet
, vol.37
, pp. 1003-1007
-
-
Gicquel, C.1
Rossignol, S.2
Cabrol, S.3
Houang, M.4
Steunou, V.5
Barbu, V.6
Danton, F.7
Thibaud, N.8
Le Merrer, M.9
Burglen, L.10
-
16
-
-
33746513103
-
A naturally occurring epigenetic mutation in a gene encoding an SBP-box transcription factor inhibits tomato fruit ripening
-
Manning K., Tor M., Poole M., Hong Y., Thompson A.J., King G.J., Giovannoni J.J., and Seymour G.B. A naturally occurring epigenetic mutation in a gene encoding an SBP-box transcription factor inhibits tomato fruit ripening. Nat Genet 38 (2006) 948-952
-
(2006)
Nat Genet
, vol.38
, pp. 948-952
-
-
Manning, K.1
Tor, M.2
Poole, M.3
Hong, Y.4
Thompson, A.J.5
King, G.J.6
Giovannoni, J.J.7
Seymour, G.B.8
-
17
-
-
11844250659
-
The developmental origins of adult disease
-
Barker D.J. The developmental origins of adult disease. J Am Coll Nutr 23 (2004) 588S-595S
-
(2004)
J Am Coll Nutr
, vol.23
-
-
Barker, D.J.1
-
18
-
-
20444411948
-
Dietary protein restriction of pregnant rats induces and folic acid supplementation prevents epigenetic modification of hepatic gene expression in the offspring
-
Lillycrop K.A., Phillips E.S., Jackson A.A., Hanson M.A., and Burdge G.C. Dietary protein restriction of pregnant rats induces and folic acid supplementation prevents epigenetic modification of hepatic gene expression in the offspring. J Nutr 135 (2005) 1382-1386
-
(2005)
J Nutr
, vol.135
, pp. 1382-1386
-
-
Lillycrop, K.A.1
Phillips, E.S.2
Jackson, A.A.3
Hanson, M.A.4
Burdge, G.C.5
-
19
-
-
33750035153
-
Diagnosis of foetal alcohol syndrome and alcohol use in pregnancy: a survey of paediatricians' knowledge, attitudes and practice
-
Elliott E.J., Payne J., Haan E., and Bower C. Diagnosis of foetal alcohol syndrome and alcohol use in pregnancy: a survey of paediatricians' knowledge, attitudes and practice. J Paediatr Child Health 42 (2006) 698-703
-
(2006)
J Paediatr Child Health
, vol.42
, pp. 698-703
-
-
Elliott, E.J.1
Payne, J.2
Haan, E.3
Bower, C.4
-
20
-
-
0043093697
-
Transposable elements: targets for early nutritional effects on epigenetic gene regulation
-
Waterland R.A., and Jirtle R.L. Transposable elements: targets for early nutritional effects on epigenetic gene regulation. Mol Cell Biol 23 (2003) 5293-5300
-
(2003)
Mol Cell Biol
, vol.23
, pp. 5293-5300
-
-
Waterland, R.A.1
Jirtle, R.L.2
-
21
-
-
11144310595
-
Intergenerational consequences of fetal programming by in utero exposure to glucocorticoids in rats
-
Drake A.J., Walker B.R., and Seckl J.R. Intergenerational consequences of fetal programming by in utero exposure to glucocorticoids in rats. Am J Physiol Regul Integr Comp Physiol 288 (2005) R34-R38
-
(2005)
Am J Physiol Regul Integr Comp Physiol
, vol.288
-
-
Drake, A.J.1
Walker, B.R.2
Seckl, J.R.3
-
22
-
-
20344385787
-
Epigenetic transgenerational actions of endocrine disruptors and male fertility
-
Anway M.D., Cupp A.S., Uzumcu M., and Skinner M.K. Epigenetic transgenerational actions of endocrine disruptors and male fertility. Science 308 (2005) 1466-1469
-
(2005)
Science
, vol.308
, pp. 1466-1469
-
-
Anway, M.D.1
Cupp, A.S.2
Uzumcu, M.3
Skinner, M.K.4
-
23
-
-
35248840160
-
Diet-induced hypermethylation at agouti viable yellow is not inherited transgenerationally through the female
-
vy mice following dietary methyl supplementation, are not transgenerationally inherited.
-
vy mice following dietary methyl supplementation, are not transgenerationally inherited.
-
(2007)
FASEB J
, vol.21
, pp. 3380-3385
-
-
Waterland, R.A.1
Travisano, M.2
Tahiliani, K.G.3
-
24
-
-
3342989681
-
Epigenetic programming by maternal behavior
-
Weaver I.C., Cervoni N., Champagne F.A., D'Alessio A.C., Sharma S., Seckl J.R., Dymov S., Szyf M., and Meaney M.J. Epigenetic programming by maternal behavior. Nat Neurosci 7 (2004) 847-854
-
(2004)
Nat Neurosci
, vol.7
, pp. 847-854
-
-
Weaver, I.C.1
Cervoni, N.2
Champagne, F.A.3
D'Alessio, A.C.4
Sharma, S.5
Seckl, J.R.6
Dymov, S.7
Szyf, M.8
Meaney, M.J.9
-
25
-
-
35548941189
-
Epigenetic epidemiology of the developmental origins hypothesis
-
Waterland R.A., and Michels K.B. Epigenetic epidemiology of the developmental origins hypothesis. Annu Rev Nutr 27 (2007) 363-388
-
(2007)
Annu Rev Nutr
, vol.27
, pp. 363-388
-
-
Waterland, R.A.1
Michels, K.B.2
-
26
-
-
0028048664
-
Neomorphic agouti mutations in obese yellow mice
-
Duhl D.M., Vrieling H., Miller K.A., Wolff G.L., and Barsh G.S. Neomorphic agouti mutations in obese yellow mice. Nat Genet 8 (1994) 59-65
-
(1994)
Nat Genet
, vol.8
, pp. 59-65
-
-
Duhl, D.M.1
Vrieling, H.2
Miller, K.A.3
Wolff, G.L.4
Barsh, G.S.5
-
27
-
-
33646481643
-
Dynamic reprogramming of DNA methylation at an epigenetically sensitive allele in mice
-
Blewitt M.E., Vickaryous N.K., Paldi A., Koseki H., and Whitelaw E. Dynamic reprogramming of DNA methylation at an epigenetically sensitive allele in mice. PLoS Genet 2 (2006) e49
-
(2006)
PLoS Genet
, vol.2
-
-
Blewitt, M.E.1
Vickaryous, N.K.2
Paldi, A.3
Koseki, H.4
Whitelaw, E.5
-
29
-
-
28044436691
-
Reversal of maternal programming of stress responses in adult offspring through methyl supplementation: altering epigenetic marking later in life
-
Weaver I.C., Champagne F.A., Brown S.E., Dymov S., Sharma S., Meaney M.J., and Szyf M. Reversal of maternal programming of stress responses in adult offspring through methyl supplementation: altering epigenetic marking later in life. J Neurosci 25 (2005) 11045-11054
-
(2005)
J Neurosci
, vol.25
, pp. 11045-11054
-
-
Weaver, I.C.1
Champagne, F.A.2
Brown, S.E.3
Dymov, S.4
Sharma, S.5
Meaney, M.J.6
Szyf, M.7
-
30
-
-
0035874481
-
The marks, mechanisms and memory of epigenetic states in mammals
-
Rakyan V.K., Preis J., Morgan H.D., and Whitelaw E. The marks, mechanisms and memory of epigenetic states in mammals. Biochem J 356 (2001) 1-10
-
(2001)
Biochem J
, vol.356
, pp. 1-10
-
-
Rakyan, V.K.1
Preis, J.2
Morgan, H.D.3
Whitelaw, E.4
-
31
-
-
0021961665
-
Further segregation analysis of the fragile X syndrome with special reference to transmitting males
-
Sherman S.L., Jacobs P.A., Morton N.E., Froster-Iskenius U., Howard-Peebles P.N., Nielsen K.B., Partington M.W., Sutherland G.R., Turner G., and Watson M. Further segregation analysis of the fragile X syndrome with special reference to transmitting males. Hum Genet 69 (1985) 289-299
-
(1985)
Hum Genet
, vol.69
, pp. 289-299
-
-
Sherman, S.L.1
Jacobs, P.A.2
Morton, N.E.3
Froster-Iskenius, U.4
Howard-Peebles, P.N.5
Nielsen, K.B.6
Partington, M.W.7
Sutherland, G.R.8
Turner, G.9
Watson, M.10
-
32
-
-
0026339303
-
Instability of a 550-base pair DNA segment and abnormal methylation in fragile X syndrome
-
Oberle I., Rousseau F., Heitz D., Kretz C., Devys D., Hanauer A., Boue J., Bertheas M., and Mandel J. Instability of a 550-base pair DNA segment and abnormal methylation in fragile X syndrome. Science 252 (1991) 1097-1102
-
(1991)
Science
, vol.252
, pp. 1097-1102
-
-
Oberle, I.1
Rousseau, F.2
Heitz, D.3
Kretz, C.4
Devys, D.5
Hanauer, A.6
Boue, J.7
Bertheas, M.8
Mandel, J.9
-
33
-
-
16944362592
-
Characterization of FMR1 promoter elements by in vivo-footprinting analysis
-
Schwemmle S., de Graaff E., Deissler H., Glaser D., Wohrle D., Kennerknecht I., Just W., Oostra B.A., Doerfler W., Vogel W., et al. Characterization of FMR1 promoter elements by in vivo-footprinting analysis. Am J Hum Genet 60 (1997) 1354-1362
-
(1997)
Am J Hum Genet
, vol.60
, pp. 1354-1362
-
-
Schwemmle, S.1
de Graaff, E.2
Deissler, H.3
Glaser, D.4
Wohrle, D.5
Kennerknecht, I.6
Just, W.7
Oostra, B.A.8
Doerfler, W.9
Vogel, W.10
-
34
-
-
0021094659
-
Parental origin of chromosome 15 deletion in Prader-Willi syndrome
-
Butler M.G., and Palmer C.G. Parental origin of chromosome 15 deletion in Prader-Willi syndrome. Lancet 1 (1983) 1285-1286
-
(1983)
Lancet
, vol.1
, pp. 1285-1286
-
-
Butler, M.G.1
Palmer, C.G.2
-
35
-
-
0024619007
-
Angelman and Prader-Willi syndromes share a common chromosome 15 deletion but differ in parental origin of the deletion
-
Knoll J.H., Nicholls R.D., Magenis R.E., Graham Jr. J.M., Lalande M., and Latt S.A. Angelman and Prader-Willi syndromes share a common chromosome 15 deletion but differ in parental origin of the deletion. Am J Med Genet 32 (1989) 285-290
-
(1989)
Am J Med Genet
, vol.32
, pp. 285-290
-
-
Knoll, J.H.1
Nicholls, R.D.2
Magenis, R.E.3
Graham Jr., J.M.4
Lalande, M.5
Latt, S.A.6
-
36
-
-
0030458551
-
Parental imprinting and human disease
-
Lalande M. Parental imprinting and human disease. Annu Rev Genet 30 (1996) 173-195
-
(1996)
Annu Rev Genet
, vol.30
, pp. 173-195
-
-
Lalande, M.1
-
37
-
-
0036642103
-
Metastable epialleles in mammals
-
Rakyan V.K., Blewitt M.E., Druker R., Preis J.I., and Whitelaw E. Metastable epialleles in mammals. Trends Genet 18 (2002) 348-351
-
(2002)
Trends Genet
, vol.18
, pp. 348-351
-
-
Rakyan, V.K.1
Blewitt, M.E.2
Druker, R.3
Preis, J.I.4
Whitelaw, E.5
-
38
-
-
33745319337
-
RNA-mediated non-Mendelian inheritance of an epigenetic change in the mouse
-
Rassoulzadegan M., Grandjean V., Gounon P., Vincent S., Gillot I., and Cuzin F. RNA-mediated non-Mendelian inheritance of an epigenetic change in the mouse. Nature 441 (2006) 469-474
-
(2006)
Nature
, vol.441
, pp. 469-474
-
-
Rassoulzadegan, M.1
Grandjean, V.2
Gounon, P.3
Vincent, S.4
Gillot, I.5
Cuzin, F.6
-
39
-
-
1242296842
-
A comprehensive analysis of allelic methylation status of CpG islands on human chromosome 21q
-
Yamada Y., Watanabe H., Miura F., Soejima H., Uchiyama M., Iwasaka T., Mukai T., Sakaki Y., and Ito T. A comprehensive analysis of allelic methylation status of CpG islands on human chromosome 21q. Genome Res 14 (2004) 247-266
-
(2004)
Genome Res
, vol.14
, pp. 247-266
-
-
Yamada, Y.1
Watanabe, H.2
Miura, F.3
Soejima, H.4
Uchiyama, M.5
Iwasaka, T.6
Mukai, T.7
Sakaki, Y.8
Ito, T.9
-
40
-
-
34247641746
-
Modifiers of epigenetic reprogramming show paternal effects in the mouse
-
This is the first report of paternal affects in mammals that the untransmitted genotype of a male parent can influence the phenotype of their offspring.
-
Chong S., Vickaryous N., Ashe A., Zamudio N., Youngson N., Hemley S., Stopka T., Skoultchi A., Matthews J., Scott H.S., et al. Modifiers of epigenetic reprogramming show paternal effects in the mouse. Nat Genet 39 (2007) 614-622. This is the first report of paternal affects in mammals that the untransmitted genotype of a male parent can influence the phenotype of their offspring.
-
(2007)
Nat Genet
, vol.39
, pp. 614-622
-
-
Chong, S.1
Vickaryous, N.2
Ashe, A.3
Zamudio, N.4
Youngson, N.5
Hemley, S.6
Stopka, T.7
Skoultchi, A.8
Matthews, J.9
Scott, H.S.10
-
41
-
-
34848905626
-
Evidence for transgenerational transmission of epigenetic tumor susceptibility in Drosophila
-
This is a report of a paternal affect in Drosophila, involving tumour susceptibility.
-
Xing Y., Shi S., Le L., Lee C.A., Silver-Morse L., and Li W.X. Evidence for transgenerational transmission of epigenetic tumor susceptibility in Drosophila. PLoS Genet 3 (2007) 1598-1606. This is a report of a paternal affect in Drosophila, involving tumour susceptibility.
-
(2007)
PLoS Genet
, vol.3
, pp. 1598-1606
-
-
Xing, Y.1
Shi, S.2
Le, L.3
Lee, C.A.4
Silver-Morse, L.5
Li, W.X.6
-
42
-
-
33751242483
-
vy allele by nutritional supplementation
-
vy mice to demonstrate that exposure to methyl donor supplementation during midgestation shifts coat colour in F1 and F2 adult offspring.
-
vy mice to demonstrate that exposure to methyl donor supplementation during midgestation shifts coat colour in F1 and F2 adult offspring.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 17308-17312
-
-
Cropley, J.E.1
Suter, C.M.2
Beckman, K.B.3
Martin, D.I.4
-
44
-
-
37349004800
-
What is an epigenetic transgenerational phenotype? F3 or F2
-
Skinner M.K. What is an epigenetic transgenerational phenotype? F3 or F2. Reprod Toxicol 25 1 (2008) 2-6
-
(2008)
Reprod Toxicol
, vol.25
, Issue.1
, pp. 2-6
-
-
Skinner, M.K.1
-
45
-
-
33646391702
-
Glucose metabolism is altered in the adequately nourished grand-offspring (F3 generation) of rats malnourished during gestation and perinatal life
-
Benyshek D.C., Johnston C.S., and Martin J.F. Glucose metabolism is altered in the adequately nourished grand-offspring (F3 generation) of rats malnourished during gestation and perinatal life. Diabetologia 49 (2006) 1117-1119
-
(2006)
Diabetologia
, vol.49
, pp. 1117-1119
-
-
Benyshek, D.C.1
Johnston, C.S.2
Martin, J.F.3
-
46
-
-
0016168382
-
Greying with age: a coat-color variant in wild Australian populations of mice
-
Kirby G.C. Greying with age: a coat-color variant in wild Australian populations of mice. J Hered 65 (1974) 126-128
-
(1974)
J Hered
, vol.65
, pp. 126-128
-
-
Kirby, G.C.1
-
47
-
-
0022400529
-
Greying with age in mice: relation to expression of murine leukemia viruses
-
Morse III H.C., Yetter R.A., Stimpfling J.H., Pitts O.M., Fredrickson T.N., and Hartley J.W. Greying with age in mice: relation to expression of murine leukemia viruses. Cell 41 (1985) 439-448
-
(1985)
Cell
, vol.41
, pp. 439-448
-
-
Morse III, H.C.1
Yetter, R.A.2
Stimpfling, J.H.3
Pitts, O.M.4
Fredrickson, T.N.5
Hartley, J.W.6
-
48
-
-
0343621494
-
Aberrant CpG-island methylation has non-random and tumour-type-specific patterns
-
Costello J.F., Fruhwald M.C., Smiraglia D.J., Rush L.J., Robertson G.P., Gao X., Wright F.A., Feramisco J.D., Peltomaki P., Lang J.C., et al. Aberrant CpG-island methylation has non-random and tumour-type-specific patterns. Nat Genet 24 (2000) 132-138
-
(2000)
Nat Genet
, vol.24
, pp. 132-138
-
-
Costello, J.F.1
Fruhwald, M.C.2
Smiraglia, D.J.3
Rush, L.J.4
Robertson, G.P.5
Gao, X.6
Wright, F.A.7
Feramisco, J.D.8
Peltomaki, P.9
Lang, J.C.10
-
50
-
-
23044514626
-
Chromosome-wide and promoter-specific analyses identify sites of differential DNA methylation in normal and transformed human cells
-
Weber M., Davies J.J., Wittig D., Oakeley E.J., Haase M., Lam W.L., and Schubeler D. Chromosome-wide and promoter-specific analyses identify sites of differential DNA methylation in normal and transformed human cells. Nat Genet 37 (2005) 853-862
-
(2005)
Nat Genet
, vol.37
, pp. 853-862
-
-
Weber, M.1
Davies, J.J.2
Wittig, D.3
Oakeley, E.J.4
Haase, M.5
Lam, W.L.6
Schubeler, D.7
-
51
-
-
33749122904
-
Heritable germline epimutation of MSH2 in a family with hereditary nonpolyposis colorectal cancer
-
This is a report of a family where individuals in three successive generations show germline and somatic epimutation at the MSH2 gene. It remains unclear whether this is an example of a primary or a secondary epimutation.
-
Chan T.L., Yuen S.T., Kong C.K., Chan Y.W., Chan A.S., Ng W.F., Tsui W.Y., Lo M.W., Tam W.Y., Li V.S., et al. Heritable germline epimutation of MSH2 in a family with hereditary nonpolyposis colorectal cancer. Nat Genet 38 (2006) 1178-1183. This is a report of a family where individuals in three successive generations show germline and somatic epimutation at the MSH2 gene. It remains unclear whether this is an example of a primary or a secondary epimutation.
-
(2006)
Nat Genet
, vol.38
, pp. 1178-1183
-
-
Chan, T.L.1
Yuen, S.T.2
Kong, C.K.3
Chan, Y.W.4
Chan, A.S.5
Ng, W.F.6
Tsui, W.Y.7
Lo, M.W.8
Tam, W.Y.9
Li, V.S.10
-
52
-
-
27744447434
-
MLH1 germline epimutations as a factor in hereditary nonpolyposis colorectal cancer
-
Hitchins M., Williams R., Cheong K., Halani N., Lin V.A., Packham D., Ku S., Buckle A., Hawkins N., Burn J., et al. MLH1 germline epimutations as a factor in hereditary nonpolyposis colorectal cancer. Gastroenterology 129 (2005) 1392-1399
-
(2005)
Gastroenterology
, vol.129
, pp. 1392-1399
-
-
Hitchins, M.1
Williams, R.2
Cheong, K.3
Halani, N.4
Lin, V.A.5
Packham, D.6
Ku, S.7
Buckle, A.8
Hawkins, N.9
Burn, J.10
-
53
-
-
33846973361
-
Inheritance of a cancer-associated MLH1 germ-line epimutation
-
This is the most convincing case to date for transgenerational inheritance of a primary epimutation in humans. An epimutation at the MLH1 allele of a mother persisted in one of three sons who inherited the allele.
-
Hitchins M.P., Wong J.J., Suthers G., Suter C.M., Martin D.I., Hawkins N.J., and Ward R.L. Inheritance of a cancer-associated MLH1 germ-line epimutation. N Engl J Med 356 (2007) 697-705. This is the most convincing case to date for transgenerational inheritance of a primary epimutation in humans. An epimutation at the MLH1 allele of a mother persisted in one of three sons who inherited the allele.
-
(2007)
N Engl J Med
, vol.356
, pp. 697-705
-
-
Hitchins, M.P.1
Wong, J.J.2
Suthers, G.3
Suter, C.M.4
Martin, D.I.5
Hawkins, N.J.6
Ward, R.L.7
-
54
-
-
34247619416
-
Heritable germline epimutation is not the same as transgenerational epigenetic inheritance
-
author reply 575-576
-
Chong S., Youngson N.A., and Whitelaw E. Heritable germline epimutation is not the same as transgenerational epigenetic inheritance. Nat Genet 39 (2007) 574-575 author reply 575-576
-
(2007)
Nat Genet
, vol.39
, pp. 574-575
-
-
Chong, S.1
Youngson, N.A.2
Whitelaw, E.3
-
55
-
-
34247642769
-
Inherited epimutation or a haplotypic basis for the propensity to silence?
-
author reply 576
-
Suter C.M., and Martin D.I. Inherited epimutation or a haplotypic basis for the propensity to silence?. Nat Genet 39 (2007) 573 author reply 576
-
(2007)
Nat Genet
, vol.39
, pp. 573
-
-
Suter, C.M.1
Martin, D.I.2
-
56
-
-
34247645078
-
Heritable germline epimutations in humans
-
author reply 575-576
-
Horsthemke B. Heritable germline epimutations in humans. Nat Genet 39 (2007) 573-574 author reply 575-576
-
(2007)
Nat Genet
, vol.39
, pp. 573-574
-
-
Horsthemke, B.1
-
57
-
-
33750212321
-
Nuclear organization of active and inactive chromatin domains uncovered by chromosome conformation capture-on-chip (4C)
-
Simonis M., Klous P., Splinter E., Moshkin Y., Willemsen R., de Wit E., van Steensel B., and de Laat W. Nuclear organization of active and inactive chromatin domains uncovered by chromosome conformation capture-on-chip (4C). Nat Genet 38 (2006) 1348-1354
-
(2006)
Nat Genet
, vol.38
, pp. 1348-1354
-
-
Simonis, M.1
Klous, P.2
Splinter, E.3
Moshkin, Y.4
Willemsen, R.5
de Wit, E.6
van Steensel, B.7
de Laat, W.8
-
58
-
-
33750203582
-
Circular chromosome conformation capture (4C) uncovers extensive networks of epigenetically regulated intra- and interchromosomal interactions
-
Zhao Z., Tavoosidana G., Sjolinder M., Gondor A., Mariano P., Wang S., Kanduri C., Lezcano M., Sandhu K.S., Singh U., et al. Circular chromosome conformation capture (4C) uncovers extensive networks of epigenetically regulated intra- and interchromosomal interactions. Nat Genet 38 (2006) 1341-1347
-
(2006)
Nat Genet
, vol.38
, pp. 1341-1347
-
-
Zhao, Z.1
Tavoosidana, G.2
Sjolinder, M.3
Gondor, A.4
Mariano, P.5
Wang, S.6
Kanduri, C.7
Lezcano, M.8
Sandhu, K.S.9
Singh, U.10
-
59
-
-
0033539183
-
An epigenetic mutation responsible for natural variation in floral symmetry
-
Cubas P., Vincent C., and Coen E. An epigenetic mutation responsible for natural variation in floral symmetry. Nature 401 (1999) 157-161
-
(1999)
Nature
, vol.401
, pp. 157-161
-
-
Cubas, P.1
Vincent, C.2
Coen, E.3
-
60
-
-
17044426694
-
Advances in sequencing technology
-
Chan E.Y. Advances in sequencing technology. Mutat Res 573 (2005) 13-40
-
(2005)
Mutat Res
, vol.573
, pp. 13-40
-
-
Chan, E.Y.1
-
61
-
-
34447569298
-
Copy number variants and genetic traits: closer to the resolution of phenotypic to genotypic variability
-
Beckmann J.S., Estivill X., and Antonarakis S.E. Copy number variants and genetic traits: closer to the resolution of phenotypic to genotypic variability. Nat Rev Genet 8 (2007) 639-646
-
(2007)
Nat Rev Genet
, vol.8
, pp. 639-646
-
-
Beckmann, J.S.1
Estivill, X.2
Antonarakis, S.E.3
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