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Volumn , Issue , 2005, Pages 175-192

Unsupervised Machine Learning to Support Functional Characterization of Genes: Emphasis on Cluster Description and Class Discovery

Author keywords

Bayesian network; Cluster homogeneity; Data integration; Function prediction; Functional genomics; Gene function prediction; Genomic data analysis; Hierarchical clustering; High throughput experimental methods; MAGIC (Multi source Association of Genes by Integration of Clusters)

Indexed keywords


EID: 84889866266     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/0470094419.ch11     Document Type: Chapter
Times cited : (1)

References (86)
  • 1
    • 0034708480 scopus 로고    scopus 로고
    • The genome sequence of Drosophila melanogaster
    • Adams, M. D. et al. (2000) The genome sequence of Drosophila melanogaster. Science, 287 (5461): 2185-2195.
    • (2000) Science , vol.287 , Issue.5461 , pp. 2185-2195
    • Adams, M.D.1
  • 2
    • 0033536012 scopus 로고    scopus 로고
    • Broad patterns of gene expression revealed by clustering analysis of tumor and normal colon tissues probed by oligonucleotide arrays
    • Alon, U., Barkai, N. et al. (1999) Broad patterns of gene expression revealed by clustering analysis of tumor and normal colon tissues probed by oligonucleotide arrays. Proc Atal Acad Sci USA, 96 (12): 6745-50.
    • (1999) Proc Atal Acad Sci USA , vol.96 , Issue.12 , pp. 6745-6750
    • Alon, U.1    Barkai, N.2
  • 4
    • 0037245913 scopus 로고    scopus 로고
    • BIND: the Biomolecular Interaction Network Database
    • Bader, G. D., Betel, D. and Hague, C. W. (2003) BIND: the Biomolecular Interaction Network Database. Nucleic Acids Res, 31 (1): 248-250.
    • (2003) Nucleic Acids Res , vol.31 , Issue.1 , pp. 248-250
    • Bader, G.D.1    Betel, D.2    Hague, C.W.3
  • 5
    • 0037756723 scopus 로고    scopus 로고
    • Functional genomics and proteomics: charting a multidimensional map of the yeast cell
    • Bader, G. D., Heilbut, A. et al. (2003) Functional genomics and proteomics: charting a multidimensional map of the yeast cell. Trends Cell Biol, 13 (7): 344-356.
    • (2003) Trends Cell Biol , vol.13 , Issue.7 , pp. 344-356
    • Bader, G.D.1    Heilbut, A.2
  • 6
    • 0036789265 scopus 로고    scopus 로고
    • Analyzing yeast protein-protein interaction data obtained from different sources
    • Bader, G. D. and Hogue, C.W. (2002) Analyzing yeast protein-protein interaction data obtained from different sources. Nat Biotechnol, 20 (10): 991-997.
    • (2002) Nat Biotechnol , vol.20 , Issue.10 , pp. 991-997
    • Bader, G.D.1    Hogue, C.W.2
  • 7
    • 0025959707 scopus 로고
    • Use of a screen for synthetic lethal and multicopy suppressee mutants to identify two new genes involved in morphogenesis in Saccharmoyces cerevisiae
    • Bender, A. and Pringle, J. R. (1991) Use of a screen for synthetic lethal and multicopy suppressee mutants to identify two new genes involved in morphogenesis in Saccharmoyces cerevisiae. Mol Cell Biol, 11 (3): 1295-1305.
    • (1991) Mol Cell Biol , vol.11 , Issue.3 , pp. 1295-1305
    • Bender, A.1    Pringle, J.R.2
  • 8
    • 0037255072 scopus 로고    scopus 로고
    • The SWISS-PROT protein knowledgebase and its supplement TrEMBL in 2003
    • Boeckmann, B., Bairoch, A. et al. (2003) The SWISS-PROT protein knowledgebase and its supplement TrEMBL in 2003. Nucleic Acids Res, 31 (1): 365-370.
    • (2003) Nucleic Acids Res , vol.31 , Issue.1 , pp. 365-370
    • Boeckmann, B.1    Bairoch, A.2
  • 9
    • 0038210252 scopus 로고    scopus 로고
    • The GRID: The General Repository for Interaction Datasets
    • PREPRINT0013
    • Breitkreutz, B. J., Stark, C. and Tyers, M. (2002) The GRID: The General Repository for Interaction Datasets. Genome Biol 3 (12): PREPRINT0013.
    • (2002) Genome Biol , vol.3 , Issue.12
    • Breitkreutz, B.J.1    Stark, C.2    Tyers, M.3
  • 10
    • 0037264524 scopus 로고    scopus 로고
    • The GRID: The General Repository for Interaction Datasets
    • Breitkreutz, B. J., Stark, C. and Tyers, M. (2003) The GRID: The General Repository for Interaction Datasets. Genome Biol, 4 (3).
    • (2003) Genome Biol , vol.4 , Issue.3
    • Breitkreutz, B.J.1    Stark, C.2    Tyers, M.3
  • 11
    • 0033655775 scopus 로고    scopus 로고
    • Mutual information relevance networks: functional genomic clustering using pairwise entropy measurements
    • Butte, A. J. and Kohane, I. S. (2000) Mutual information relevance networks: functional genomic clustering using pairwise entropy measurements. Poc Symp Biocomput, 418-429.
    • (2000) Poc Symp Biocomput , pp. 418-429
    • Butte, A.J.1    Kohane, I.S.2
  • 12
    • 0141720418 scopus 로고    scopus 로고
    • Protein arrays and their role in proteomics
    • Cahill, D. J. and Nordhoff, E. (2003) Protein arrays and their role in proteomics. Adv Biochem Eng Biotechnol 83: 177-187.
    • (2003) Adv Biochem Eng Biotechnol , vol.83 , pp. 177-187
    • Cahill, D.J.1    Nordhoff, E.2
  • 13
    • 0036012375 scopus 로고    scopus 로고
    • Evaluation and comparison of clustering algorithms in analyzing ES cell gene expression data
    • Chen, G., Jaradat, S. A. et al. (2002) Evaluation and comparison of clustering algorithms in analyzing ES cell gene expression data. Statistica Sinica 12: 241-262.
    • (2002) Statistica Sinica , vol.12 , pp. 241-262
    • Chen, G.1    Jaradat, S.A.2
  • 14
    • 0038135024 scopus 로고    scopus 로고
    • Computational analyses of high-throughput protein-protein interaction data
    • Chen, Y. and Xu, D. (2003) Computational analyses of high-throughput protein-protein interaction data. Curr Protein Pept Sci, 4 (3): 159-181.
    • (2003) Curr Protein Pept Sci , vol.4 , Issue.3 , pp. 159-181
    • Chen, Y.1    Xu, D.2
  • 16
    • 0032509302 scopus 로고    scopus 로고
    • Genome sequence of the nematode C. elegans: a platform for investigating biology
    • Consortium, T. C. E. S. (1998) Genome sequence of the nematode C. elegans: a platform for investigating biology. Science, 282 (5396): 2012-2018.
    • (1998) Science , vol.282 , Issue.5396 , pp. 2012-2018
    • Consortium, T.C.E.S.1
  • 17
    • 0037253089 scopus 로고    scopus 로고
    • Protein arrays: the current state-of-the-art
    • Cutler, P. (2003) Protein arrays: the current state-of-the-art. Preteomics, 3 (1): 3-18.
    • (2003) Preteomics , vol.3 , Issue.1 , pp. 3-18
    • Cutler, P.1
  • 18
    • 0036580169 scopus 로고    scopus 로고
    • Protein interactions: two methods for assessment of the reliability of high throughput observations
    • Deance, C. M., L. Salwinski, et al. (2002) Protein interactions: two methods for assessment of the reliability of high throughput observations. Mol Cell Proteomics, 1 (5): 349-356.
    • (2002) Mol Cell Proteomics , vol.1 , Issue.5 , pp. 349-356
    • Deance, C.M.1    Salwinski, L.2
  • 19
    • 0036087548 scopus 로고    scopus 로고
    • Saccharomyces Genome Database (SGD) provides secondary gene annotation using the Gene Ontology (GO)
    • Dwight, S. S., M. A. Harris, et al. (2002) Saccharomyces Genome Database (SGD) provides secondary gene annotation using the Gene Ontology (GO). Nucleic Acids Res 30 (1): 69-72.
    • (2002) Nucleic Acids Res , vol.30 , Issue.1 , pp. 69-72
    • Dwight, S.S.1    Harris, M.A.2
  • 20
    • 0036081355 scopus 로고    scopus 로고
    • Gene Expression Omnibus: NCBI gene expression and hybridization array data repository
    • Edgar, R., Domrachev, M. and Lash, A. E. (2002) Gene Expression Omnibus: NCBI gene expression and hybridization array data repository. Nucleic Acids Res, 30 (1): 207-10.
    • (2002) Nucleic Acids Res , vol.30 , Issue.1 , pp. 207-210
    • Edgar, R.1    Domrachev, M.2    Lash, A.E.3
  • 21
    • 0036805329 scopus 로고    scopus 로고
    • Bridging structural biology and genomics: assessing protein interaction data with known complexes
    • Edwards, A. M., Kus, B. et al. (2002) Bridging structural biology and genomics: assessing protein interaction data with known complexes. Trends Genet, 18 (10): 529-36.
    • (2002) Trends Genet , vol.18 , Issue.10 , pp. 529-536
    • Edwards, A.M.1    Kus, B.2
  • 22
    • 0032441150 scopus 로고    scopus 로고
    • Cluster analysis and display of genome-wide expression patterns
    • Eisen, M. B., Spellman, P. T. et al. (1998) Cluster analysis and display of genome-wide expression patterns. Proc Nat Acad Sci USA 95 (25):, 14, 863-8.
    • (1998) Proc Nat Acad Sci USA 95 (25): , vol.14 , pp. 863-868
    • Eisen, M.B.1    Spellman, P.T.2
  • 23
    • 0033061199 scopus 로고    scopus 로고
    • An algorithmic approach to multiple complete digest mapping
    • Fasulo, D., T. Jiang, et al. (1999) An algorithmic approach to multiple complete digest mapping. J Comput Biol, 6 (2): 187-207.
    • (1999) J Comput Biol , vol.6 , Issue.2 , pp. 187-207
    • Fasulo, D.1    Jiang, T.2
  • 24
    • 0024406857 scopus 로고
    • A novel genetic system to detect protein-protein interactions
    • Fields, S. and Song, O. (1989) A novel genetic system to detect protein-protein interactions. Nature, 340 (6230): 245-6.
    • (1989) Nature , vol.340 , Issue.6230 , pp. 245-246
    • Fields, S.1    Song, O.2
  • 25
    • 0033707946 scopus 로고    scopus 로고
    • Using Bayesian networks to analyze expression data
    • Friedman, N., M. Linial, et al. (2000) Using Bayesian networks to analyze expression data. J Comput Biol 7 (3-4): 601-20.
    • (2000) J Comput Biol , vol.7 , Issue.3-4 , pp. 601-620
    • Friedman, N.1    Linial, M.2
  • 26
    • 0033637153 scopus 로고    scopus 로고
    • Genomic expression programs in the response of yeast cells to environments changes
    • Gasch, A. P., P. T. Spellman, et al. (2000) Genomic expression programs in the response of yeast cells to environments changes. Mol Biol Cell, 11 (12): 4241-57.
    • (2000) Mol Biol Cell , vol.11 , Issue.12 , pp. 4241-4257
    • Gasch, A.P.1    Spellman, P.T.2
  • 27
    • 0035733690 scopus 로고    scopus 로고
    • Correlation between transcriptome and interactome mapping data from Saccharomyces cerevisiae
    • Ge, H., Z. Liu et al. (2001) Correlation between transcriptome and interactome mapping data from Saccharomyces cerevisiae. Nat Genet, 29 (4): 482-6.
    • (2001) Nat Genet , vol.29 , Issue.4 , pp. 482-486
    • Ge, H.1    Liu, Z.2
  • 28
    • 0037059506 scopus 로고    scopus 로고
    • Proteomics. Integrating interactomes
    • Gerstein, M., Lan, N. and Jansen, R. (2002) Proteomics. Integrating interactomes. Science, 295 (5553): 284-7.
    • (2002) Science , vol.295 , Issue.5553 , pp. 284-287
    • Gerstein, M.1    Lan, N.2    Jansen, R.3
  • 29
    • 0036188158 scopus 로고    scopus 로고
    • Mixture modelling of gene expression data from microarray experiments
    • Ghosh, D. and Chinnaiyan, A. M. (2002) Mixture modelling of gene expression data from microarray experiments. Bioinformatics, 18 (2): 275-86.
    • (2002) Bioinformatics , vol.18 , Issue.2 , pp. 275-286
    • Ghosh, D.1    Chinnaiyan, A.M.2
  • 30
    • 0036798238 scopus 로고    scopus 로고
    • Judging the quality of gene expression-based clustering methods using gene annotation
    • Gibbons, F. D. and Roth, F. P. (2002) Judging the quality of gene expression-based clustering methods using gene annotation. Genome Res, 12 (10): 1574-81.
    • (2002) Genome Res , vol.12 , Issue.10 , pp. 1574-1581
    • Gibbons, F.D.1    Roth, F.P.2
  • 31
    • 10244239321 scopus 로고    scopus 로고
    • Life with 6000 genes
    • Goffeau, A., Barrell, B. G. et al. (1996) Life with 6000 genes. Science, 274 (5287): 546-567.
    • (1996) Science , vol.274 , Issue.5287 , pp. 546-567
    • Goffeau, A.1    Barrell, B.G.2
  • 32
    • 0036733722 scopus 로고    scopus 로고
    • Treasures and traps in genome-wide data sets: case examples from yeast
    • Grunenfelder, B. and Winzeler, E. A. (2002) Treasures and traps in genome-wide data sets: case examples from yeast. Nat Rev Genet, 3 (9): 653-61.
    • (2002) Nat Rev Genet , vol.3 , Issue.9 , pp. 653-661
    • Grunenfelder, B.1    Winzeler, E.A.2
  • 33
    • 0003505654 scopus 로고
    • Probabilistic Similarity Networks
    • MIT Press, Cambridge, MA
    • Heckerman, D. (1991) Probabilistic Similarity Networks. MIT Press, Cambridge, MA.
    • (1991)
    • Heckerman, D.1
  • 34
    • 0002370418 scopus 로고    scopus 로고
    • A tutorial on learning with Bayesian networks. Learning in Graphical Models
    • M. I. Jordan (ed.) MIT Press, Cambridge, MA
    • Heckerman, D. (1999) A tutorial on learning with Bayesian networks. Learning in Graphical Models, M. I. Jordan (ed.) MIT Press, Cambridge, MA, 301-354.
    • (1999) , pp. 301-354
    • Heckerman, D.1
  • 35
    • 0346423698 scopus 로고    scopus 로고
    • Protein arrays, an excellent tool in biomedical research
    • Huang, R. P. (2003) Protein arrays, an excellent tool in biomedical research. Front Biosci 8: d559-76.
    • (2003) Front Biosci , vol.8
    • Huang, R.P.1
  • 37
    • 0036699526 scopus 로고    scopus 로고
    • Revealing modular organization in the yeast transcriptional network
    • Ihmels, J., G. Friedlander, et al. (2002) Revealing modular organization in the yeast transcriptional network. Nat Genet, 31 (4): 370-7.
    • (2002) Nat Genet , vol.31 , Issue.4 , pp. 370-377
    • Ihmels, J.1    Friedlander, G.2
  • 38
    • 0036372453 scopus 로고    scopus 로고
    • Estimation of genetic networks and functional structures between genes by using Bayesian networks and nonparametric regression
    • Imoto, S., Goto, T. and Miyam, S. (2002) Estimation of genetic networks and functional structures between genes by using Bayesian networks and nonparametric regression. Pac Symp Biocomput. 175-86.
    • (2002) Pac Symp Biocomput. , pp. 175-186
    • Imoto, S.1    Goto, T.2    Miyam, S.3
  • 39
  • 40
    • 0035836765 scopus 로고    scopus 로고
    • A comprehensive two-hybrid analysis to explore the yeast protein interacetone
    • Ito, T., T. Chiba, et al. (2001) A comprehensive two-hybrid analysis to explore the yeast protein interacetone. Proc Natl Acad Sci USA, 98 (8): 4569-74.
    • (2001) Proc Natl Acad Sci USA , vol.98 , Issue.8 , pp. 4569-4574
    • Ito, T.1    Chiba, T.2
  • 41
    • 0036279153 scopus 로고    scopus 로고
    • Protein interaction verification and functional annotation by integrated analysis of genome-scale data
    • Kemmeren, P., N. L. Van Berkum, et al. (2002) Protein interaction verification and functional annotation by integrated analysis of genome-scale data. Mol Cell, 9 (5): 1133-43.
    • (2002) Mol Cell , vol.9 , Issue.5 , pp. 1133-1143
    • Kemmeren, P.1    Van Berkum, N.L.2
  • 42
    • 0035979259 scopus 로고    scopus 로고
    • Bootstrapping cluster analysis: assessing the reliability of conclusions from microarray experiments
    • Kerr, M. K. and Churchill, G. A. (2001) Bootstrapping cluster analysis: assessing the reliability of conclusions from microarray experiments. Proc Natl Acad Sci USA, 98 (16): 8961-5.
    • (2001) Proc Natl Acad Sci USA , vol.98 , Issue.16 , pp. 8961-8965
    • Kerr, M.K.1    Churchill, G.A.2
  • 43
    • 0036941857 scopus 로고    scopus 로고
    • Looking beyond the details: a rise in system-oriented approaches in genetics and molecular biology
    • Kitano, H. (2002) Looking beyond the details: a rise in system-oriented approaches in genetics and molecular biology. Curr Genet, 41 (1): 1-10.
    • (2002) Curr Genet , vol.41 , Issue.1 , pp. 1-10
    • Kitano, H.1
  • 44
    • 2042437650 scopus 로고    scopus 로고
    • Initial sequencing and analysis of the human genome
    • Lander, E. S., L. M. Linton et al. (2001) Initial sequencing and analysis of the human genome. Nature, 409 (6822): 860-921.
    • (2001) Nature , vol.409 , Issue.6822 , pp. 860-921
    • Lander, E.S.1    Linton, L.M.2
  • 45
    • 0018790602 scopus 로고
    • Affinity precipitation of enzymes
    • Larsson, P. O. and Mosbach, K. (1979) Affinity precipitation of enzymes. FEBS Lett, 98 (2): 333-338.
    • (1979) FEBS Lett , vol.98 , Issue.2 , pp. 333-338
    • Larsson, P.O.1    Mosbach, K.2
  • 46
    • 0003499480 scopus 로고    scopus 로고
    • Plaid models for gene expression data
    • Technical Report
    • Lazzeroni, L. and Owen, A. B. (2000) Plaid models for gene expression data. Technical Report.
    • (2000)
    • Lazzeroni, L.1    Owen, A.B.2
  • 47
    • 84984933234 scopus 로고    scopus 로고
    • High density synthetic oligonucleotide arrays
    • Lipshutz, R. J., S. P. Fodor, et al. (1999) High density synthetic oligonucleotide arrays. Nat Genet 21 (Suppl 1): 20-4.
    • (1999) Nat Genet , vol.21 , Issue.SUPPL. 1 , pp. 20-24
    • Lipshutz, R.J.1    Fodor, S.P.2
  • 48
    • 0035014159 scopus 로고    scopus 로고
    • Analysis of temporal gene expression profiles: clustering by simulated annealing and determining the optimal number of clusters
    • Lukashin, A. V. and R. Fuchs (2001) Analysis of temporal gene expression profiles: clustering by simulated annealing and determining the optimal number of clusters. Bioinformatics 17 (5): 405-14.
    • (2001) Bioinformatics , vol.17 , Issue.5 , pp. 405-414
    • Lukashin, A.V.1    Fuchs, R.2
  • 49
    • 0035755746 scopus 로고    scopus 로고
    • Exploiting big biology: integrating large-scale biological data for function inference
    • Marcotte, E. and Date, S. (2001) Exploiting big biology: integrating large-scale biological data for function inference. Brief Bioinform, 2 (4): 363-74.
    • (2001) Brief Bioinform , vol.2 , Issue.4 , pp. 363-374
    • Marcotte, E.1    Date, S.2
  • 50
    • 0033618555 scopus 로고    scopus 로고
    • Detecting protein function and protein-protein interactions from genome sequences
    • Marcotte, E. M., M. Pellegrini, et al. (1999a) Detecting protein function and protein-protein interactions from genome sequences. Science 285 (5428): 751-3.
    • (1999) Science , vol.285 , Issue.5428 , pp. 751-753
    • Marcotte, E.M.1    Pellegrini, M.2
  • 51
    • 0033523854 scopus 로고    scopus 로고
    • A combined algorithm for genome-wide prediction of protein function
    • Marcotte, E. M., M. Pellegrini, et al. (1999b) A combined algorithm for genome-wide prediction of protein function. Nature 402 (6757): 83-6.
    • (1999) Nature , vol.402 , Issue.6757 , pp. 83-86
    • Marcotte, E.M.1    Pellegrini, M.2
  • 52
    • 0036203115 scopus 로고    scopus 로고
    • A mixture model-based approach to the clustering of microarray expression data
    • McLachlan, G. J., Bean, R.W. and Peel, D. (2002) A mixture model-based approach to the clustering of microarray expression data. Bioinformatics, 18 (3): 413-22.
    • (2002) Bioinformatics , vol.18 , Issue.3 , pp. 413-422
    • McLachlan, G.J.1    Bean, R.W.2    Peel, D.3
  • 53
    • 0036081347 scopus 로고    scopus 로고
    • MIPS: a database for genomes and protein sequences
    • Mewes, H. W., D. Frishman, et al. (2002) MIPS: a database for genomes and protein sequences. Nucleic Acids Res, 30 (1): 31-4.
    • (2002) Nucleic Acids Res , vol.30 , Issue.1 , pp. 31-34
    • Mewes, H.W.1    Frishman, D.2
  • 54
    • 0035162931 scopus 로고    scopus 로고
    • A genomic study of the bipolar bud site selection pattern in Saccharomyces cerevisiae
    • Ni, L. and Snyder, M. (2001) A genomic study of the bipolar bud site selection pattern in Saccharomyces cerevisiae. Mol Biol Cell, 12 (7): 2147-70.
    • (2001) Mol Biol Cell , vol.12 , Issue.7 , pp. 2147-2170
    • Ni, L.1    Snyder, M.2
  • 55
    • 0024549504 scopus 로고
    • Suppressors of yeast actin mutations
    • Novick, P., Osmond, B. C. and Botstein, D. (1989) Suppressors of yeast actin mutations. Genetics, 121 (4): 659-74.
    • (1989) Genetics , vol.121 , Issue.4 , pp. 659-674
    • Novick, P.1    Osmond, B.C.2    Botstein, D.3
  • 56
    • 0041877535 scopus 로고    scopus 로고
    • Self-assembling protein arrays using electronic semiconductor microchips and in vitro translation
    • Oleinikov, A. V., M. D. Gray, et al. (2003) Self-assembling protein arrays using electronic semiconductor microchips and in vitro translation. J Proteome Res, 2 (3): 313-9.
    • (2003) J Proteome Res , vol.2 , Issue.3 , pp. 313-319
    • Oleinikov, A.V.1    Gray, M.D.2
  • 57
    • 0002887785 scopus 로고    scopus 로고
    • Gene functional classification from heterogeneous data
    • Pavlidis, P., J.Weston, et al. (2001) Gene functional classification from heterogeneous data. Proc Int Conf Intell Syst Mol Biol 5: 242-248.
    • (2001) Proc Int Conf Intell Syst Mol Biol , vol.5 , pp. 242-248
    • Pavlidis, P.1    Weston, J.2
  • 58
    • 0002887785 scopus 로고    scopus 로고
    • Gene functional classification from heterogeneous data
    • Pavlidis, P., J.Weston, et al. (2001) Gene functional classification from heterogeneous data. Proc Int Conf Intell Syst Mol Biol 5: 242-248.
    • (2001) Proc Int Conf Intell Syst Mol Biol , vol.5 , pp. 242-248
    • Pavlidis, P.1    Weston, J.2
  • 59
    • 0036100116 scopus 로고    scopus 로고
    • Learning gene functional classifications from multiple data types
    • Pavlidis, P., J.Weston, et al. (2002) Learning gene functional classifications from multiple data types. J Comput Biol, 9 (2): 401-11.
    • (2002) J Comput Biol , vol.9 , Issue.2 , pp. 401-411
    • Pavlidis, P.1    Weston, J.2
  • 60
    • 0003391330 scopus 로고
    • Probabilistic Reasoning in Intelligent Systems: Networks of Plausible Inference
    • Kaufmann, San Mateo, CA
    • Pearl, J. (1988) Probabilistic Reasoning in Intelligent Systems: Networks of Plausible Inference. Kaufmann, San Mateo, CA.
    • (1988)
    • Pearl, J.1
  • 61
    • 0013203966 scopus 로고    scopus 로고
    • FunSpec: a web-based cluster interpreter for yeast
    • Robinson, M. D., J. Grigull, et al. (2002) FunSpec: a web-based cluster interpreter for yeast. BMC Bioinformatics 3 (1): 35.
    • (2002) BMC Bioinformatics , vol.3 , Issue.1 , pp. 35
    • Robinson, M.D.1    Grigull, J.2
  • 62
    • 0035221559 scopus 로고    scopus 로고
    • Percolation clustering: a novel approach to the clustering of gene expression patterns in Dictyostelium development
    • Sasik, R., T. Hwa, et al. (2001) Percolation clustering: a novel approach to the clustering of gene expression patterns in Dictyostelium development. Pac Symp Biocomput, 335-47.
    • (2001) Pac Symp Biocomput , pp. 335-347
    • Sasik, R.1    Hwa, T.2
  • 63
    • 0028806048 scopus 로고
    • Quantitative monitoring of gene expression patterns with a complementary DNA microarray
    • Schena, M., D. Shalon, et al. (1995) Quantitative monitoring of gene expression patterns with a complementary DNA microarray. Science, 270 (5235): 467-70.
    • (1995) Science , vol.270 , Issue.5235 , pp. 467-470
    • Schena, M.1    Shalon, D.2
  • 64
    • 0033669189 scopus 로고    scopus 로고
    • A network of protein-protein interactions in yeast
    • Schwikowski, B., Uetz, P. and Fields, S. (2000) A network of protein-protein interactions in yeast. Nat Biotechnol, 18 (12): 1257-61.
    • (2000) Nat Biotechnol , vol.18 , Issue.12 , pp. 1257-1261
    • Schwikowski, B.1    Uetz, P.2    Fields, S.3
  • 65
    • 0037941585 scopus 로고    scopus 로고
    • Module networks: identifying regulatory modules and their condition-specific regulators from gene expression data
    • Segal, E., M. Shapira, et al (2003) Module networks: identifying regulatory modules and their condition-specific regulators from gene expression data. Nat Genet 34 (2): 166-76.
    • (2003) Nat Genet , vol.34 , Issue.2 , pp. 166-176
    • Segal, E.1    Shapira, M.2
  • 66
    • 0141506116 scopus 로고    scopus 로고
    • CLICK and EXPANDER: a system for clustering and visualizing gene expression data
    • Sharan, R., Maron-Katz, A. and Shamir, R. (2003) CLICK and EXPANDER: a system for clustering and visualizing gene expression data. Bioinformatics, 19 (14): 1787-99.
    • (2003) Bioinformatics , vol.19 , Issue.14 , pp. 1787-1799
    • Sharan, R.1    Maron-Katz, A.2    Shamir, R.3
  • 67
    • 0034565041 scopus 로고    scopus 로고
    • CLICK: a clustering algorithm with applications to gene expression analysis
    • Sharan, R. and Shamir, R. (2000) CLICK: a clustering algorithm with applications to gene expression analysis. Proc Int Conf Intell Syst Mol Biol, 8: 307-16.
    • (2000) Proc Int Conf Intell Syst Mol Biol , vol.8 , pp. 307-316
    • Sharan, R.1    Shamir, R.2
  • 68
    • 0034062083 scopus 로고    scopus 로고
    • Analysis of large-scale gene expression data
    • Sherlock, G. (2000) Analysis of large-scale gene expression data. Curr Opin Immunol, 12 (2): 201-5.
    • (2000) Curr Opin Immunol , vol.12 , Issue.2 , pp. 201-205
    • Sherlock, G.1
  • 70
    • 3042654830 scopus 로고    scopus 로고
    • Protein expression of profiling arrays: tools for the multiplexed highthroughput analysis of proteins
    • Sydor, J. R. and Nock, S. (2003) Protein expression of profiling arrays: tools for the multiplexed highthroughput analysis of proteins. Proteome Sci 1 (1): 3.
    • (2003) Proteome Sci , vol.1 , Issue.1 , pp. 3
    • Sydor, J.R.1    Nock, S.2
  • 71
    • 0033027794 scopus 로고    scopus 로고
    • Interpreting patterns of gene expression with self-organizing maps: methods and application to hematopoietic differentiation
    • Tamayo, P., D. Slonim, et al. (1999) Interpreting patterns of gene expression with self-organizing maps: methods and application to hematopoietic differentiation. Proc Natl Acad Sci USA, 96 (6): 2907-12.
    • (1999) Proc Natl Acad Sci USA , vol.96 , Issue.6 , pp. 2907-2912
    • Tamayo, P.1    Slonim, D.2
  • 72
    • 0037059461 scopus 로고    scopus 로고
    • A combined experimental and computational strategy to define protein interaction networks for peptide recognition modules
    • Tong, A. H., B. Drees, et al. (2002) A combined experimental and computational strategy to define protein interaction networks for peptide recognition modules. Science, 295 (5553): 321-4.
    • (2002) Science , vol.295 , Issue.5553 , pp. 321-324
    • Tong, A.H.1    Drees, B.2
  • 73
    • 0038492417 scopus 로고    scopus 로고
    • A Bayesian framework for combining heterogenous data sources for gene function prediction (in Saccharomyces cerevisiae)
    • Troyanskaya, O. G., K. Dolinski, et al. (2003) A Bayesian framework for combining heterogenous data sources for gene function prediction (in Saccharomyces cerevisiae) Proc Natl Acad Sci USA 100 (14): 8348-53.
    • (2003) Proc Natl Acad Sci USA , vol.100 , Issue.14 , pp. 8348-8353
    • Troyanskaya, O.G.1    Dolinski, K.2
  • 74
    • 0033515542 scopus 로고    scopus 로고
    • Cef1p is a component of the Prp 19p-associated complex and essential for pre-mRNA splicing
    • Tsai, W. Y., Y. T. Chow, et al. (1999) Cef1p is a component of the Prp 19p-associated complex and essential for pre-mRNA splicing. J Biol Chem, 274 (14): 9455-62.
    • (1999) J Biol Chem , vol.274 , Issue.14 , pp. 9455-9462
    • Tsai, W.Y.1    Chow, Y.T.2
  • 75
    • 0037192335 scopus 로고    scopus 로고
    • A role for Rad23 proteins in 26S proteasomedependent protein degradation?
    • Van Laar, T., Van der Eb, A. J. and Tevleth, C. (2002) A role for Rad23 proteins in 26S proteasomedependent protein degradation? Mutat Res 499 (1): 53-61.
    • (2002) Mutat Res , vol.499 , Issue.1 , pp. 53-61
    • Van Laar, T.1    Van der Eb, A.J.2    Tevleth, C.3
  • 76
    • 0035895505 scopus 로고    scopus 로고
    • The sequence of the human genome
    • Venter, J. C., M. D. Adams, et al. (2001) The sequence of the human genome. Science, 291 (5507): 1304-51.
    • (2001) Science , vol.291 , Issue.5507 , pp. 1304-1351
    • Venter, J.C.1    Adams, M.D.2
  • 77
    • 0037161731 scopus 로고    scopus 로고
    • Comparative assessment of large-scale data sets of protein-protein interactions
    • Von Mering, C., R. Krause, et al. (2002) Comparative assessment of large-scale data sets of protein-protein interactions. Nature, 417 (6887): 399-403.
    • (2002) Nature , vol.417 , Issue.6887 , pp. 399-403
    • Von Mering, C.1    Krause, R.2
  • 78
    • 0036796488 scopus 로고    scopus 로고
    • Comparative analysis of multiple genome-scale data sets
    • Werner-Washburne, M., B. Wylie, et al. (2002) Comparative analysis of multiple genome-scale data sets. Genome Res, 12 (10): 1564-73.
    • (2002) Genome Res , vol.12 , Issue.10 , pp. 1564-1573
    • Werner-Washburne, M.1    Wylie, B.2
  • 79
    • 0343907206 scopus 로고    scopus 로고
    • Protein functions in pre-mRNA splicing
    • Will, C. L. and Luhrmann, R. (1997) Protein functions in pre-mRNA splicing. Curr Opin Cell Biol, 9 (3): 320-8.
    • (1997) Curr Opin Cell Biol , vol.9 , Issue.3 , pp. 320-328
    • Will, C.L.1    Luhrmann, R.2
  • 80
    • 0037148758 scopus 로고    scopus 로고
    • The genome sequence of Schizosaccharomyces pombe
    • Wood, V., R. Gwilliam, et al. (2002) The genome sequence of Schizosaccharomyces pombe. Nature, 415 (6874): 871-80.
    • (2002) Nature , vol.415 , Issue.6874 , pp. 871-880
    • Wood, V.1    Gwilliam, R.2
  • 81
    • 0036088133 scopus 로고    scopus 로고
    • DIP, the Database of Interacting Proteins: a research tool for studying cellular networks of protein interactions
    • Xenarios, I., L. Salwinski, et al. (2002) DIP, the Database of Interacting Proteins: a research tool for studying cellular networks of protein interactions. Nucleic Acids Res, 30 (1): 303-5.
    • (2002) Nucleic Acids Res , vol.30 , Issue.1 , pp. 303-305
    • Xenarios, I.1    Salwinski, L.2
  • 82
    • 0034782618 scopus 로고    scopus 로고
    • Model-based clustering and data transformations for gene expression data
    • Yeung, K. Y., C. Fraley, et al. (2001) Model-based clustering and data transformations for gene expression data. Bioinformatics, 17 (10): 977-87.
    • (2001) Bioinformatics , vol.17 , Issue.10 , pp. 977-987
    • Yeung, K.Y.1    Fraley, C.2
  • 83
    • 0035024021 scopus 로고    scopus 로고
    • Validating clustering for gene expression data
    • Yeung, K. Y., Haynor, D. R. and Ruzzo, W. L. (2001) Validating clustering for gene expression data. Bioinformatics, 17 (4): 309-18.
    • (2001) Bioinformatics , vol.17 , Issue.4 , pp. 309-318
    • Yeung, K.Y.1    Haynor, D.R.2    Ruzzo, W.L.3
  • 84
    • 0035872073 scopus 로고    scopus 로고
    • An evaluation of the performance of cDNA microassays for detecting changes in global mRNA expression
    • Yue, H., P. S. Eastman, et al. (2001) An evaluation of the performance of cDNA microassays for detecting changes in global mRNA expression. Nucleic Acids Res 29 (8): E41-1.
    • (2001) Nucleic Acids Res , vol.29 , Issue.8
    • Yue, H.1    Eastman, P.S.2
  • 85
    • 0037138406 scopus 로고    scopus 로고
    • MINT: a Molecular INTeraction database
    • Zanzoni, A., L. Montecchi-Palazzi, et al. (2002) MINT: a Molecular INTeraction database. FEBS Lett, 513 (1): 135-40.
    • (2002) FEBS Lett , vol.513 , Issue.1 , pp. 135-140
    • Zanzoni, A.1    Montecchi-Palazzi, L.2
  • 86
    • 0032861774 scopus 로고    scopus 로고
    • SCPD: a promoter database of the yeast Saccharomyces cerevisiae
    • Zhu, J. and Zhang, M. Q. (1999) SCPD: a promoter database of the yeast Saccharomyces cerevisiae. Bioinformatics. 15 (7/8): 607-11.
    • (1999) Bioinformatics. , vol.15 , Issue.7-8 , pp. 607-611
    • Zhu, J.1    Zhang, M.Q.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.