Carbon monoxide form of PEGylated hemoglobin protects myocardium against ischemia/reperfusion injury in diabetic and normal mice

Artificial Cells, Nanomedicine and Biotechnology

Volumn 41, Issue 6, 2013, Pages 428-436

  Ananthakrishnan, Radha ^a   Li, Qing ^a   O'Shea, Karen M ^a   Quadri, Nosirudeen ^a   Wang, Lingjie ^b   Abuchowski, Abraham ^c   Schmidt, Ann Marie ^a   Ramasamy, Ravichandran ^a  

^a NEW YORK UNIVERSITY MEDICAL CENTER   (United States)

^b SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^c Prolong Pharmaceuticals   (United States)

Author keywords

Blood; Carbon monoxide; Diabetes; Myocardial infarction; PEGylated hemoglobin; Substitute

Indexed keywords

ACUTE CORONARY SYNDROMES; CORONARY ARTERIES; INFARCT SIZE; ISCHEMIA/REPERFUSION; LEFT ANTERIOR DESCENDING; MYOCARDIAL INFARCTION; PEGYLATED HEMOGLOBINS; SUBSTITUTE;

BLOOD; HEMOGLOBIN; MAMMALS; MEDICAL PROBLEMS;

CARBON MONOXIDE;

ADENOSINE TRIPHOSPHATE; BUPRENORPHINE; CARBON MONOXIDE; GLUCOSE; HEMOGLOBIN DERIVATIVE; MALONALDEHYDE; PEGYLATED HEMOGLOBIN; SANGUINATE; STREPTOZOCIN; TROPONIN C; TROPONIN I; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY LIGATION; DRUG DOSAGE FORM; DRUG EFFICACY; ENERGY METABOLISM; GLUCOSE BLOOD LEVEL; HEART FUNCTION; HEART INFARCTION; HEART INFARCTION SIZE; HEART LEFT VENTRICLE EJECTION FRACTION; HEART MUSCLE; HEART MUSCLE REPERFUSION; HEART PROTECTION; IN VIVO STUDY; MOUSE; NONHUMAN; OXIDATIVE STRESS; POSTOPERATIVE PAIN; PROTEIN BLOOD LEVEL; REPERFUSION INJURY; SINGLE DRUG DOSE; STREPTOZOCIN DIABETES; TRANSTHORACIC ECHOCARDIOGRAPHY;

ANIMALS; BIOLOGICAL MARKERS; BLOOD SUBSTITUTES; CARBON MONOXIDE; DIABETES COMPLICATIONS; ENERGY METABOLISM; HEART; HEMOGLOBINS; MICE; MYOCARDIAL INFARCTION; MYOCARDIAL REPERFUSION INJURY; OXIDATIVE STRESS; POLYETHYLENE GLYCOLS; TIME FACTORS;

EID: 84889684370     PISSN: 21691401     EISSN: 2169141X     Source Type: Journal    
DOI: 10.3109/21691401.2012.762370     Document Type: Article

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